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1. 发明申请

WO2017145119A1 ESTIMATION OF GLUCOSE RATE OF APPEARANCE FROM CGS AND SUBCUTANEOUS INSULIN DELIVERY IN TYPE 1 DIABETES 审中-公开
标题翻译： 1型糖尿病患者CGS和皮下注射胰岛素释放的葡萄糖率评估
公开(公告)号：WO2017145119A1
公开(公告)日：2017-08-31
申请号：PCT/IB2017/051100
申请日：2017-02-24
申请人： KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY , PRINCE SULTAN UNIVERSITY
发明人： LALEG, Taous Meriem , AL-MATOUQ, Ali Ahmed
IPC分类号： A61B5/00 , A61B5/145 , G06F19/00
CPC分类号： A61B5/4839 , A61B5/14532 , A61B5/7278 , A61M5/00 , A61M5/14244 , A61M2205/3303 , A61M2205/3523 , A61M2205/50 , A61M2205/52 , A61M2230/005 , A61M2230/201 , G06F19/00 , G06F19/3468 , G16H50/50
摘要： Method and System for providing estimates of Glucose Rate of Appearance from the intestine (GRA) using continuous glucose sensor measurements (CGS) taken from the subcutaneous of a diabetes patient and the amount of insulin administered to the patient.
摘要翻译：用于使用从糖尿病患者的皮下采集的连续葡萄糖传感器测量值（CGS）和施用给患者的胰岛素的量来提供来自肠的葡萄糖出现率（GRA）的估计的方法和系统

2. 发明申请

WO2020170090A1 MODEL PREDICTIVE CONTROL PARADIGMS FOR DIRECT CONTACT MEMBRANE DISTILLATION 审中-公开
公开(公告)号：WO2020170090A1
公开(公告)日：2020-08-27
申请号：PCT/IB2020/051219
申请日：2020-02-13
申请人： KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY
发明人： LALEG, Taous Meriem , ALBALAWI, Fahad , GUO, Xingang
IPC分类号： B01D61/36 , G05B13/04 , G05B17/02
摘要： A method for controlling a direct contact membrane distillation (DCMD) system (500), the method including modeling (1700) the DCMD system (500) with differential-algebraic equations (DAEs), wherein the DAEs include process states x( t k ) and an input state u(t k ); selecting (1702) a value for the input variable u(t k ) for a time t k ; estimating (1704) the process states x( t k ) based on the DAEs and the input state u(t k ); checking (1706) that a boundedness function G applied to the process states x (t k ) is smaller than a desired steady-state point ρ e ; and minimizing (1708) an objective function, which depends on the process states x( t k ) and the input state u(t k ), to determine an updated input state u(t k+1 ) for a next time t k+1 . The process states x( t k ) include temperatures and heat flow rates.

3. 发明申请

WO2019077449A1 MAGNETIC RESONANCE SPECTROSCOPY WATER SUPPRESSION METHOD AND DEVICE 审中-公开
公开(公告)号：WO2019077449A1
公开(公告)日：2019-04-25
申请号：PCT/IB2018/057899
申请日：2018-10-11
申请人： KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY , UNIVERSITEIT GENT (RUG)
发明人： LALEG, Taous Meriem , SERRAI, Hacene , CHAHID, Abderrazak
IPC分类号： G01R33/46
CPC分类号： G01R33/4625
摘要： A method for suppressing a water line in an acquired magnetic resonance spectra (MRS) y, the method including receiving (800) the acquired MRS spectra y; estimating (802) a water peak ywp for the acquired MRS spectra y using squared eigenfunctions ( ψ ) of a Schrodinger operator H; and removing (804) the water peak y wp from the acquired MRS y to obtain a suppressed water MRS spectra y ws . The suppressed water MRS spectra y ws includes a signature of one or more metabolites.

4. 发明申请

WO2020170101A1 REDUCED FEATURE GENERATION FOR SIGNAL CLASSIFICATION BASED ON A POSITION WEIGHT MATRIX 审中-公开
公开(公告)号：WO2020170101A1
公开(公告)日：2020-08-27
申请号：PCT/IB2020/051272
申请日：2020-02-14
申请人： KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY
发明人： LALEG, Taous Meriem , ALBALAWI, Fahad Ali , CHAHID, Abderrazak
IPC分类号： G06K9/00 , A61B5/055
摘要： A method for classifying input data includes receiving (1000) the input data (104) that describe an object (101), wherein the input data (104) corresponds to plural classes; associating (1002) the input data (104) with voxels (106) that describe the object (101); calculating (1004) a real-number sequence X(n), which is associated with a measured parameter P that describes the object (101); quantizing (1006) the real-number sequence X(n) to generate a finite set sequence Q(n), where n describes a number of levels; generating (1008) a voxel-based weight matrix for each class of the input data; and calculating (1010) a score S for each class of the plural classes, based on a corresponding voxel-based weight matrix. The score S is a number that indicates a likelihood that the input data associated with a given sample belongs to a class of the plural classes.

5. 发明申请

WO2017029600A1 ROBUST LYAPUNOV CONTROLLER FOR UNCERTAIN SYSTEMS 审中-公开
标题翻译：用于不确定系统的稳健LYAPUNOV控制器
公开(公告)号：WO2017029600A1
公开(公告)日：2017-02-23
申请号：PCT/IB2016/054884
申请日：2016-08-13
申请人： KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY
发明人： LALEG, Taous Meriem , ELMETENNANI, Shahrazed
IPC分类号： G05B13/04 , G05B17/02
CPC分类号： G05B13/048 , G05B17/02
摘要： Various examples of systems and methods are provided for Lyapunov control for uncertain systems. In one example, a system includes a process plant and a robust Lyapunov controller configured to control an input of the process plant. The robust Lyapunov controller includes an inner closed loop Lyapunov controller and an outer closed loop error stabilizer. In another example, a method includes monitoring a system output of a process plant; generating an estimated system control input based upon a defined output reference; generating a system control input using the estimated system control input and a compensation term; and adjusting the process plant based upon the system control input to force the system output to track the defined output reference. An inner closed loop Lyapunov controller can generate the estimated system control input and an outer closed loop error stabilizer can generate the system control input.
摘要翻译：为不确定系统的Lyapunov控制提供了各种系统和方法的例子。在一个示例中，系统包括处理设备和被配置为控制过程工厂的输入的鲁棒的Lyapunov控制器。鲁棒的Lyapunov控制器包括内部闭环Lyapunov控制器和外部闭环误差稳定器。在另一示例中，一种方法包括监视过程工厂的系统输出; 基于定义的输出参考生成估计的系统控制输入; 使用估计的系统控制输入和补偿项产生系统控制输入; 以及基于系统控制输入来调整过程工厂，以迫使系统输出跟踪定义的输出参考。内部闭环Lyapunov控制器可以生成估计的系统控制输入，外部闭环误差稳定器可以产生系统控制输入。

6. 发明申请

WO2020170102A1 FEATURE GENERATION BASED ON EIGENFUNCTIONS OF THE SCHRÖDINGER OPERATOR 审中-公开
公开(公告)号：WO2020170102A1
公开(公告)日：2020-08-27
申请号：PCT/IB2020/051275
申请日：2020-02-14
申请人： KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY
发明人： LALEG, Taous Meriem , CHAHID, Abderrazak
IPC分类号： G16H50/20 , G16H50/70
摘要： A method for generating a feature (330) associated with input data includes receiving (900) the input data (300); projecting (902) the input data (300) with a set of square functions ψ 2 nh of the Schrödinger operator; selecting (904) the feature (330) to be a number of the negative eigenvalues λ nh of the Schrödinger operator; and classifying (906) the input data (300) based on the feature (330).

7. 发明申请

WO2017175115A1 SMART MEMBRANES FOR MONITORING MEMBRANE BASED DESALINATION PROCESSES 审中-公开
标题翻译：用于监测膜基脱盐过程的智能膜
公开(公告)号：WO2017175115A1
公开(公告)日：2017-10-12
申请号：PCT/IB2017/051894
申请日：2017-04-03
申请人： KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY
发明人： LALEG, Taous Meriem , KARAM, Ayman Mustafa
IPC分类号： B01D61/36 , B01D65/10
摘要： Various examples are related to smart membranes for monitoring membrane based process such as, e.g., membrane distillation processes. In one example, a membrane, includes a porous surface and a plurality of sensors (e.g., temperature, flow and/or impedance sensors) mounted on the porous surface. In another example, a membrane distillation (MD) process includes the membrane. Processing circuitry can be configured to monitor outputs of the plurality of sensors. The monitored outputs can be used to determine membrane degradation, membrane fouling, or to provide an indication of membrane replacement or cleaning. The sensors can also provide temperatures or temperature differentials across the porous surface, which can be used to improve modeling or control the MD process.
摘要翻译：各种实例涉及用于监测基于膜的工艺的智能膜，例如膜蒸馏工艺。在一个示例中，膜包括多孔表面和安装在多孔表面上的多个传感器（例如，温度，流量和/或阻抗传感器）。在另一个实例中，膜蒸馏（MD）工艺包括膜。处理电路可以被配置成监视多个传感器的输出。监测的输出可用于确定膜降解，膜污染或提供膜置换或清洁的指示。传感器还可以提供多孔表面的温度或温差，可用于改善建模或控制MD过程。

8. 发明申请

WO2017002077A1 CONTROL OF DISTRIBUTED HEAT TRANSFER MECHANISMS IN MEMBRANE DISTILLATION PLANTS 审中-公开
标题翻译：膜分散植物分布式热转移机理的控制
公开(公告)号：WO2017002077A1
公开(公告)日：2017-01-05
申请号：PCT/IB2016/053946
申请日：2016-06-30
申请人： KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY
发明人： LALEG, Taous Meriem , ELEIWI, Fadi , KARAM, Ayman
IPC分类号： B01D61/36 , G05B17/00
CPC分类号： B01D61/364 , B01D61/366 , G05B17/00
摘要： Various examples are provided that are related to boundary control in membrane distillation (MD) processes. In one example, a system includes a membrane distillation (MD) process comprising a feed side and a permeate side separated by a membrane boundary layer; and processing circuitry configured to control a water production rate of the MD process based at least in part upon a distributed heat transfer across the membrane boundary layer. In another example, a method includes determining a plurality of estimated temperature states of a membrane boundary layer separating a feed side and a permeate side of a membrane distillation (MD) process; and adjusting inlet flow rate or inlet temperature of at least one of the feed side or the permeate side to maintain a difference temperature along the membrane boundary layer about a defined reference temperature based at least in part upon the plurality of estimated temperature states.
摘要翻译：提供了与膜蒸馏（MD）工艺中的边界控制有关的各种实例。在一个实例中，系统包括膜蒸馏（MD）方法，其包括由膜边界层分离的进料侧和渗透侧; 以及处理电路，其被配置为至少部分地基于跨越所述膜边界层的分布式热传递来控制所述MD过程的产水率。在另一个实例中，一种方法包括确定分离膜蒸馏（MD）方法的进料侧和渗透侧的膜边界层的多个估计温度状态; 以及调节进料侧或渗透侧中的至少一个的入口流速或入口温度，以至少部分地基于所述多个估计的温度状态，将围绕所述膜边界层的差温度围绕限定的参考温度维持。

9. 发明申请

WO2022190006A1 CENTRAL BLOOD PRESSURE ESTIMATION BASED ON PHOTOPLETHYSMOGRAPHY DATA 审中-公开
公开(公告)号：WO2022190006A1
公开(公告)日：2022-09-15
申请号：PCT/IB2022/052116
申请日：2022-03-09
申请人： KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY
发明人： LALEG, Taous Meriem , LI, Peihao
IPC分类号： A61B5/021 , A61B5/00
摘要： A method for estimating blood pressure related quantities associated with a patient includes receiving (1300) a photoplethysmography, PPG, signal (132), wherein the PPG signal (132) is collected with a single PPG sensor; extracting (1302) plural semi-classical signal analysis, SCSA, features (128) from the PPG signal (132), by using a Schrodinger operator; processing (1304) the plural SCSA features (128) at processor (122) with a machine learning algorithm module (130), to calculate negative eigenvalues (kn) and associated eigenfunctions (ψn ) of the Schrodinger operator, wherein n varies between 1 and Nh, Nh is a total number of negative eigenvalues (kn ), and h is a semi-classical constant; and calculating (1306) the blood pressure related quantities (132, 134) based on (1) the calculated negative eigenvalues (kn) and (2) the associated eigenfunctions (ψn) of the Schrodinger operator.

10. 发明申请

WO2020079528A1 MATHEMATICAL BIOMARKER FOR ARTERIAL VISCOELASTICITY ASSESSMENT 审中-公开
公开(公告)号：WO2020079528A1
公开(公告)日：2020-04-23
申请号：PCT/IB2019/058566
申请日：2019-10-08
申请人： KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY
发明人： LALEG, Taous Meriem , BAHLOUL, Mohamed Abdelwaheb
IPC分类号： A61B5/02
摘要： A method for assessing a state of a cardiovascular system includes receiving (1600) a blood pressure Pa and a blood flow Qa of the cardiovascular system; calculating (1602) with a fractional-order, viscoelastic Windkessel model (400) an arterial compliance C α of the cardiovascular system; and evaluating (1604) the state of the cardiovascular system based on a fractional-order parameter α associated with the fractional-order, viscoelastic Windkessel model (400).

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