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11. 发明申请

WO2011076103A1 METHOD AND DEVICE FOR DETECTING PWM WAVE 审中-公开
标题翻译：用于检测PWM波的方法和装置
公开(公告)号：WO2011076103A1
公开(公告)日：2011-06-30
申请号：PCT/CN2010/080050
申请日：2010-12-21
申请人： BYD COMPANY LIMITED , LIU, Yu , SHEN, Xiaofeng , ZHANG, Jianhua
发明人： LIU, Yu , SHEN, Xiaofeng , ZHANG, Jianhua
IPC分类号： G01R29/02
CPC分类号： G01R29/0273 , G01R29/02
摘要： A method for detecting PWM wave comprises: starting counting when a PWM wave is detected; interrupting the counting when a value of the counting reaches a predetermined value; determining whether electric level of the PWM wave during the interruption is high electric level or low electric level; clearing the value of the counting, starting a next counting and interrupting the next counting when a value of the next counting reaches the predetermined value; determining whether the electric level of the PWM wave during the interruption of the next counting is high electric level or low electric level; clearing the value of the counting and repeating the counting and the determining until one period of the PWM wave; and calculating a duty ratio of the PWM wave based on a number of high electric level and a number of low electric level determined within one period of the PWM wave.
摘要翻译：一种用于检测PWM波的方法包括：当检测到PWM波时开始计数; 当计数值达到预定值时中断计数; 确定中断期间PWM波的电平是高电平还是低电平; 清除计数值，开始下一个计数，并且当下次计数的值达到预定值时中断下一个计数; 确定下次计数中断期间的PWM波的电平是高电平还是低电平; 清除计数值，重复计数和确定直到PWM波的一个周期; 以及基于在PWM波的一个周期内确定的高电平和低电平的数量来计算PWM波的占空比。

12. 发明申请

WO2011060342A3 CARDIAC DIFFERENTIATION OF HUMAN PLURIPOTENT STEM CELLS UNDER DEFINED CONDITIONS USING MATRIX OVERLAY METHODS 审中-公开
标题翻译：定义条件下基质重叠法分化人多能干细胞的心肌细胞分化
公开(公告)号：WO2011060342A3
公开(公告)日：2011-05-19
申请号：PCT/US2010/056653
申请日：2010-11-15
申请人： WISCONSIN ALUMNI RESEARCH FOUNDATION , KAMP, Timothy, J. , ZHANG, Jianhua , AZARIN, Samira , PALECEK, Sean , LIAN, Xiaojun
发明人： KAMP, Timothy, J. , ZHANG, Jianhua , AZARIN, Samira , PALECEK, Sean , LIAN, Xiaojun
IPC分类号： C12N5/077
摘要： Methods for culturing the pluripotent stem cells to undergo epithelial-to-mesenchymal transition and for generating high-yield, high-purity cardiomyocyte cultures from pluripotent stem cells are described. Pluripotent stem cells are cultured on a support with an overlaid matrix and, optionally, exposed to one or more factors to induce epithelial-to-mesenchymal transition and cardiogenesis.
摘要翻译：描述了培养多能干细胞进行上皮 - 间质转化并用于从多能干细胞产生高产量，高纯度心肌细胞培养物的方法。将多能干细胞在具有覆盖基质的支持物上培养，并任选地暴露于一种或多种因子以诱导上皮 - 间质转化和心脏发生。

13. 发明申请

WO2008066635A1 OPPOSED PUMPING LOAD HIGH PRESSURE COMMON RAIL FUEL PUMP 审中-公开
标题翻译：对位泵送高压普通铁路燃油泵
公开(公告)号：WO2008066635A1
公开(公告)日：2008-06-05
申请号：PCT/US2007/022740
申请日：2007-10-26
申请人： CATERPILLAR INC. , SHAFER, Scott, F. , TRUBNIKOV, Timur , LOVE V, William, John , REBHOLZ, Heather , ZHANG, Jianhua
发明人： SHAFER, Scott, F. , TRUBNIKOV, Timur , LOVE V, William, John , REBHOLZ, Heather , ZHANG, Jianhua
IPC分类号： F04B1/04 , F04B1/053 , F04B9/04 , F04B49/24 , F02M59/06 , F04B1/02
CPC分类号： F04B1/0413 , F02M59/06 , F02M59/366 , F02M63/0295 , F02M2200/03 , F04B1/02 , F04B1/0538 , F04B9/042 , F04B49/24 , F04B2201/1202 , F04B2201/1207
摘要： A high volume high pressure common rail (16, 17) pump (12) for a fuel system (10) includes pairs of pump head assemblies in phase with each other but oriented in opposition to one another about a rotating cam shaft (52). Pump pistons (91, 95) in the pump head assemblies simultaneously undergo pumping strokes via a shared two lobe cam (68, 69) of the rotating cam shaft (52). The pump (12) may include two pairs of pump head assemblies, and each head assembly may include two pump pistons (91, 95). The cam shaft (52) includes two cams (68, 69) sufficiently out of phase with one another that the cam shaft (52) always has a positive torque even when the cam lobes (68, 69) are symmetrical. In addition, because the pumping is done simultaneously on opposite sides of the cam shaft (52), the forces on the cam shaft (52) are balanced and its support bearings experience less wear and tear.
摘要翻译：用于燃料系统（10）的高容量高压共轨（16,17）泵（12）包括彼此同相的但相对于旋转的凸轮轴（52）相对定向的一对泵头组件。泵头组件中的泵活塞（91,95）同时通过旋转的凸轮轴（52）的共享的两个凸角（68,69）进行泵送冲程。泵（12）可以包括两对泵头组件，并且每个头组件可以包括两个泵活塞（91,95）。凸轮轴（52）包括彼此充分异相的两个凸轮（68,69），即使当凸轮凸角（68,69）对称时，凸轮轴（52）总是具有正转矩。此外，由于在凸轮轴（52）的相对侧同时进行泵送，所以凸轮轴（52）上的力是平衡的，并且其支撑轴承经历较少的磨损。

14. 发明申请

WO2011060342A8 CARDIAC DIFFERENTIATION OF HUMAN PLURIPOTENT STEM CELLS UNDER DEFINED CONDITIONS USING MATRIX OVERLAY METHODS 审中-公开
标题翻译：使用矩阵覆盖方法定义的条件下人类间质干细胞的心脏分化
公开(公告)号：WO2011060342A8
公开(公告)日：2012-05-03
申请号：PCT/US2010056653
申请日：2010-11-15
申请人： WISCONSIN ALUMNI RES FOUND , KAMP TIMOTHY J , ZHANG JIANHUA , AZARIN SAMIRA , PALECEK SEAN , LIAN XIAOJUN
发明人： KAMP TIMOTHY J , ZHANG JIANHUA , AZARIN SAMIRA , PALECEK SEAN , LIAN XIAOJUN
IPC分类号： C12N5/077
CPC分类号： C12N5/0657 , C12N2501/155 , C12N2501/16 , C12N2501/727 , C12N2506/02 , C12N2506/45
摘要： Methods for culturing the pluripotent stem cells to undergo epithelial-to-mesenchymal transition and for generating high-yield, high-purity cardiomyocyte cultures from pluripotent stem cells are described. Pluripotent stem cells are cultured on a support with an overlaid matrix and, optionally, exposed to one or more factors to induce epithelial-to-mesenchymal transition and cardiogenesis.
摘要翻译：描述了培养多能干细胞进行上皮 - 间质转化和从多能干细胞产生高产量，高纯度心肌细胞培养物的方法。多能干细胞在具有重叠基质的载体上培养，并且任选地暴露于一种或多种因子以诱导上皮 - 间质转化和心脏发生。

15. 发明申请

WO2010081427A1 BATTERY MANAGING DEVICE, METHOD OF USING THE SAME AND CHARGING MANAGEMENT METHOD OF BATTERY PACK 审中-公开
标题翻译：电池管理装置，使用该电池的方法和电池组的充电管理方法
公开(公告)号：WO2010081427A1
公开(公告)日：2010-07-22
申请号：PCT/CN2010/070217
申请日：2010-01-15
申请人： BYD COMPANY LIMITED , DENG, Linwang , WU, Xuejian , ZHANG, Jianhua
发明人： DENG, Linwang , WU, Xuejian , ZHANG, Jianhua
IPC分类号： H02J7/00
CPC分类号： H02J7/0052 , H02J7/045 , H02J7/047 , H02J2007/005
摘要： A battery managing device, a method of using the same and a charging management method of a battery pack. The battery managing device comprises a single-chip (25) for determining a charging voltage and a charging current according to a remaining capacity of the battery pack and controlling a charging device coupled to the battery managing device to charge the battery pack with the charging voltage and the charging current determined by the single-chip (25).
摘要翻译：电池管理装置，其使用方法和电池组的充电管理方法。电池管理装置包括用于根据电池组的剩余容量来确定充电电压和充电电流的单芯片（25），并控制耦合到电池管理装置的充电装置以对充电电压进行充电和由单片（25）确定的充电电流。

16. 发明申请

WO2009073131A2 SYNCHRONIZING COMMON RAIL PUMPING EVENTS WITH ENGINE OPERATION 审中-公开
标题翻译：与发动机运行同步通用铁路泵送事件
公开(公告)号：WO2009073131A2
公开(公告)日：2009-06-11
申请号：PCT/US2008013140
申请日：2008-11-25
申请人： CATERPILLAR INC , SHAFER SCOTT , ZHANG JIANHUA , IBRAHIM DANIEL
发明人： SHAFER SCOTT , ZHANG JIANHUA , IBRAHIM DANIEL
IPC分类号： F02M37/04
CPC分类号： F02M63/0225 , F02M39/00
摘要： Noise and vibrations associated with a common rail fuel system (12) drive linkage (31) are reduced by synchronizing a high pressure common rail (24) supply pump with engine operation. This may be accomplished by selecting a linkage (31) associated with a desired ratio of engine speed to pump speed along with selecting a number of pump plungers and cam lobes (35) that results in synchronizing action of the pump with engine combustion events. In particular, a pattern of pumping events (80) per engine cycle repeats during each engine cycle. In a more sophisticated version, the pattern of pumping events (80) per engine cycle includes a sub-pattern of pumping events (80) that repeats an integer number of times each engine cycle, where the integer number equals the number of engine cylinders (15).
摘要翻译：通过使高压共轨（24）供应泵与发动机操作同步，减少与共轨燃料系统（12）驱动联动装置（31）相关联的噪声和振动。这可以通过选择与期望的发动机转速与泵速的比率相关联的联动装置（31）以及选择一些泵柱塞和凸轮凸角（35）来实现，这导致泵与发动机燃烧事件的同步动作。特别地，每个发动机循环的泵送事件（80）的模式在每个发动机循环期间重复。在更复杂的版本中，每个发动机循环的泵送事件（80）的模式包括泵送事件的子模式（80），其重复每个发动机循环的整数次，其中整数等于发动机气缸的数量 15）。

17. 发明申请

WO2006041829A3 ANTAGONIST PEPTIDES TO THE C5A CHEMOTACTIC FUNCTION OF VITAMIN D BINDING PROTEIN 审中-公开
标题翻译：维生素D结合蛋白C5A化学功能的拮抗剂
公开(公告)号：WO2006041829A3
公开(公告)日：2009-04-16
申请号：PCT/US2005035653
申请日：2005-10-05
申请人： KEW RICHARD R , ZHANG JIANHUA
发明人： KEW RICHARD R , ZHANG JIANHUA
IPC分类号： C07K14/00
CPC分类号： C07K14/57 , A61K38/00
摘要： It has been demonstrated that one of Vitamin D Binding Protein (DBP) biological functions is to enhance the chemotactic activity of C5a and C5a des Arg. The present invention has found that peptides having sequences that substantially correspond to a specific region in the N-terminal domain I of DBP can block the DBP enhancement of C5a or C5a des Arg chemotactic activity. Based in this discovery the present invention provides DBP antagonist peptides and the use thereof for the treatment C5a or C5a des Arg-mediated disorders.
摘要翻译：已经证明维生素D结合蛋白（DBP）生物学功能之一是提高C5a和C5a des Arg的趋化活性。本发明已经发现，具有基本上对应于DBP的N末端结构域I中的特定区域的序列的肽可以阻断C5a或C5a des Arg趋化活性的DBP增强。基于该发现，本发明提供DBP拮抗剂肽及其用于治疗C5a或C5a des Arg介导的病症的用途。

18. 发明申请

WO2009009378A2 CATHEPSIN-D NEUROPROTECTION 审中-公开
标题翻译： CATHEPSIN-D神经保护
公开(公告)号：WO2009009378A2
公开(公告)日：2009-01-15
申请号：PCT/US2008069041
申请日：2008-07-02
申请人： UAB RESEARCH FOUNDATION , UNIV ALABAMA , ZHANG JIANHUA , CALDWELL GUY
发明人： ZHANG JIANHUA , CALDWELL GUY
IPC分类号： A61K31/47 , A61K38/00 , C07K5/12
CPC分类号： A61K31/47 , A61K38/488 , G01N33/5023 , G01N33/5088
摘要： Provided herein are methods and compositions for promoting neuroprotection in a subject and for treating a neural disorder associated with protein aggregation comprising administering to the subject an agent that increases expression or activity of cathepsin-D. Also provided are methods of screening for agents that increase expression or activity of cathepsin-D and methods of screening for neuroprotective agents.
摘要翻译：本文提供用于促进受试者中的神经保护并用于治疗与蛋白质聚集相关的神经疾病的方法和组合物，所述方法和组合物包含向所述受试者施用增加组织蛋白酶-D表达或活性的试剂。还提供筛选增加组织蛋白酶-D的表达或活性的试剂的方法和筛选神经保护剂的方法。

19. 发明申请

WO2008077346A1 HYBRID POWER OUTPUT SYSTEM 审中-公开
标题翻译：混合动力输出系统
公开(公告)号：WO2008077346A1
公开(公告)日：2008-07-03
申请号：PCT/CN2007/071298
申请日：2007-12-21
申请人： BYD COMPANY LIMITED , WANG, Chuanfu , LUO, Hongbin , CHEN, Wei , ZHANG, Jianhua , LIAO, Yunhao , SONG, Youchuan
发明人： WANG, Chuanfu , LUO, Hongbin , CHEN, Wei , ZHANG, Jianhua , LIAO, Yunhao , SONG, Youchuan
IPC分类号： B60K6/387 , B60K6/442
CPC分类号： B60K6/387 , B60K1/02 , B60K6/40 , B60K6/442 , B60L3/0061 , B60L11/123 , B60L11/1868 , B60L15/2045 , B60L2210/40 , B60L2220/14 , B60L2220/46 , B60L2240/12 , B60L2240/421 , B60L2240/423 , B60L2240/441 , B60L2240/443 , Y02T10/6217 , Y02T10/6234 , Y02T10/645 , Y02T10/7005 , Y02T10/7066 , Y02T10/7077 , Y02T10/7241 , Y02T10/7283
摘要： A hybrid power output system fore outputting the power to the wheel driving shaft (8), comprising an engine (1), a first motor (2), a second motor (3), a battery (6), a first clutch (4), a second clutch (5) and a third clutch (11), wherein: the first motor (2) and second motor (3) are connected electrically with the battery (6); the engine (1) is connected to the first motor (2) via the first clutch (4); the first motor (2) is connected to a wheel driving shaft (8) via the second clutch (4); the second motor (3) is connected to the wheel driving shaft via the third clutch (11); the second clutch and the third clutch are arranged between the first motor and second motor. This hybrid power output system is compact in structure, can increase the power efficiency and reduce the fuel consumption, and can realize multiple drive modes.
摘要翻译：一种混合动力输出系统，其将动力输出到车轮驱动轴（8），包括发动机（1），第一电动机（2），第二电动机（3），电池（6），第一离合器（4）），第二离合器（5）和第三离合器（11），其中：第一马达（2）和第二马达（3）与电池（6）电连接; 发动机（1）经由第一离合器（4）连接到第一电动机（2）; 第一马达（2）经由第二离合器（4）连接到车轮驱动轴（8）; 第二电动机（3）经由第三离合器（11）连接到车轮驱动轴; 第二离合器和第三离合器布置在第一马达和第二马达之间。该混合动力输出系统结构紧凑，可提高功率效率，降低燃油消耗，实现多种驱动模式。

20. 发明申请

WO2006136100A1 POWER SUPPLYING DEVICE AND POWER SUPPLYING METHOD 审中-公开
标题翻译：电源设备和供电方法
公开(公告)号：WO2006136100A1
公开(公告)日：2006-12-28
申请号：PCT/CN2006/001407
申请日：2006-06-21
申请人： BYD COMPANY LIMITED , ZHANG, Jianhua , YU, Hongbo , QI, Jun , LI, Lin
发明人： ZHANG, Jianhua , YU, Hongbo , QI, Jun , LI, Lin
IPC分类号： H02J7/00
CPC分类号： H02J7/0068 , H02J7/0065
摘要： A power supplying device comprises a DC/DC power supplying module, a storage battery, a charging module and an isolating diode. The input terminal of the DC/DC power supplying module is connected to the input terminal of the charging module to receive the electric power from an external DC power source. The output terminal of the charging module is connected to the positive electrodes of both the isolating diode and the storage battery. The negative electrode of the storage battery is grounded. The negative electrode of the isolating diode is connected to the output terminal of the DC/DC power supplying module to supply electric power to a load.
摘要翻译：供电装置包括DC / DC供电模块，蓄电池，充电模块和隔离二极管。 DC / DC供电模块的输入端子连接到充电模块的输入端子，以从外部直流电源接收电力。充电模块的输出端子连接到隔离二极管和蓄电池的正电极。蓄电池的负极接地。隔离二极管的负极连接到DC / DC供电模块的输出端，向负载供电。

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