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    • 15. 发明申请
    • INTRAGASTRIC IMPLANTS WITH COLLAPSIBLE FRAMES
    • 具有可折叠框架的INTRAGASTRIC植入物
    • WO2012054297A4
    • 2012-09-20
    • PCT/US2011056167
    • 2011-10-13
    • ALLERGAN INCDOMINGUEZ ZACHARY PBABKES MITCHELL HSCHWAB JUSTIN JMUDD CHRISTOPHER SHOOVER JASON
    • DOMINGUEZ ZACHARY PBABKES MITCHELL HSCHWAB JUSTIN JMUDD CHRISTOPHER SHOOVER JASON
    • A61F5/00
    • A61F5/0036A61F5/0033A61F5/0079A61F5/0086A61F5/0089
    • Transoral obesity treatment devices and related methods for operation thereof are described which occupy space within a stomach and/or stimulate the stomach wall. The transoral obesity treatment devices and related methods are intended to assist a patient in maintaining a healthy body weight. Features of the devices include insertion transorally and without invasive surgery, without associated patient risks of invasive surgery, and without substantial patient discomfort. The life span of these devices may be material-dependent upon long-term survivability within an acidic stomach, but is intended to last one year or longer. The devices have the capacity to vary in size and are desirably self-actuating in that they change shape and/or volume using internal motors or actuators. The changing character of the devices helps prevent the person's stomach from compensating for the implant, such as sometimes happens with static intragastric devices.
    • 描述了口腔肥胖治疗装置及其操作的相关方法,其占据胃内空间和/或刺激胃壁。 口腔肥胖治疗装置和相关方法旨在帮助患者维持健康的体重。 这些装置的特征包括经口插入并且没有侵入性手术,没有相关的患者侵入性手术风险,并且没有实质性的患者不适。 这些装置的使用寿命可能与材料有关,因为这些装置在酸性胃中具有长期生存能力,但意图持续一年或更长时间。 这些装置具有能够在尺寸上变化的能力,并且期望自动致动,因为它们使用内部马达或致动器改变形状和/或体积。 装置的变化特征有助于防止人的胃部补偿植入物,例如有时会发生静态的胃内装置。
    • 16. 发明申请
    • RE-SHAPING INTRAGASTRIC IMPLANTS
    • 重新形成INTRAGASTRIC植入物
    • WO2012051108A4
    • 2012-08-23
    • PCT/US2011055598
    • 2011-10-10
    • ALLERGAN INCBABKES MITCHELL HDOMINGUEZ ZACHARY PMUDD CHRISTOPHER SRAVEN JOSEPH S
    • BABKES MITCHELL HDOMINGUEZ ZACHARY PMUDD CHRISTOPHER SRAVEN JOSEPH S
    • A61F5/00
    • A61F5/0036
    • The present application provides implantable intragastric devices for the treatment of obesity. The intragastric devices advantageously act as a volume-occupying device, and is able to survive implantation in a patient's stomach for a year or longer. In addition, the intragastric devices may be configured to stimulate an inner stomach wall and/or temporarily block the pylorus to slow gastric emptying and/or be rotationally variant, thereby encouraging different stimulation points on the inner wall of the stomach and limiting the stomach's ability to adapt over long term implantation. The intragastric devices may reshape the stomach cavity, such as by pushing on opposite sides so as to "planarize" the stomach. For instance, the device may be an inflated disk, or an implantable loop or a springy coil that may be straightened for delivery/extraction yet assume the loop or coil shape upon implant.
    • 本申请提供了用于治疗肥胖的可植入胃内装置。 胃内装置有利地用作体积占有装置,并且能够在患者的胃中植入一年或更长时间。 此外,胃内装置可以被配置为刺激内部胃壁和/或临时阻塞幽门以减缓胃排空和/或旋转变异,由此鼓励胃内壁上的不同刺激点并限制胃的能力 适应长期植入。 胃内装置可以重新形成胃腔,例如通过推动相对侧以便使胃平坦化。 例如,该装置可以是充气盘,或可植入环或弹性线圈,其可以被拉直以用于递送/提取,但在植入时呈现环或线圈形状。
    • 17. 发明申请
    • RE-SHAPING INTRAGASTRIC IMPLANTS
    • 重新形成的INTRAGASTRIC植入
    • WO2012051108A3
    • 2012-07-05
    • PCT/US2011055598
    • 2011-10-10
    • ALLERGAN INCBABKES MITCHELL HDOMINGUEZ ZACHARY PMUDD CHRISTOPHER SRAVEN JOSEPH S
    • BABKES MITCHELL HDOMINGUEZ ZACHARY PMUDD CHRISTOPHER SRAVEN JOSEPH S
    • A61F5/00
    • A61F5/0036
    • The present application provides implantable intragastric devices for the treatment of obesity. The intragastric devices advantageously act as a volume-occupying device, and is able to survive implantation in a patient's stomach for a year or longer. In addition, the intragastric devices may be configured to stimulate an inner stomach wall and/or temporarily block the pylorus to slow gastric emptying and/or be rotationally variant, thereby encouraging different stimulation points on the inner wall of the stomach and limiting the stomach's ability to adapt over long term implantation. The intragastric devices may reshape the stomach cavity, such as by pushing on opposite sides so as to "planarize" the stomach. For instance, the device may be an inflated disk, or an implantable loop or a springy coil that may be straightened for delivery/extraction yet assume the loop or coil shape upon implant.
    • 本申请提供了用于治疗肥胖症的可植入胃内装置。 胃内装置有利地用作体积占用装置,并且能够在患者的胃中植入一年或更长时间。 此外,胃内装置可构造成刺激胃内壁和/或暂时阻塞幽门以减缓胃排空和/或旋转变化,从而促进胃内壁上的不同刺激点并限制胃的能力 以适应长期植入。 胃内装置可以重塑胃腔,例如通过推动相对侧以便“平面化”胃。 例如,该装置可以是充气盘,或者可植入环或弹性线圈,其可以被拉直以用于递送/提取,但在植入时呈现环或线圈形状。