专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2012054297A3 INTRAGASTRIC IMPLANTS WITH COLLAPSIBLE FRAMES 审中-公开
标题翻译：具有可拉框的INTRAGASTRIC植入物
公开(公告)号：WO2012054297A3
公开(公告)日：2012-08-02
申请号：PCT/US2011056167
申请日：2011-10-13
申请人： ALLERGAN INC , DOMINGUEZ ZACHARY P , BABKES MITCHELL H , SCHWAB JUSTIN J , MUDD CHRISTOPHER S , HOOVER JASON
发明人： DOMINGUEZ ZACHARY P , BABKES MITCHELL H , SCHWAB JUSTIN J , MUDD CHRISTOPHER S , HOOVER JASON
IPC分类号： A61F5/00
CPC分类号： A61F5/0036 , A61F5/0033 , A61F5/0079 , A61F5/0086 , A61F5/0089
摘要： Transoral obesity treatment devices and related methods for operation thereof are described which occupy space within a stomach and/or stimulate the stomach wall. The transoral obesity treatment devices and related methods are intended to assist a patient in maintaining a healthy body weight. Features of the devices include insertion transorally and without invasive surgery, without associated patient risks of invasive surgery, and without substantial patient discomfort. The life span of these devices may be material-dependent upon long-term survivability within an acidic stomach, but is intended to last one year or longer. The devices have the capacity to vary in size and are desirably self-actuating in that they change shape and/or volume using internal motors or actuators. The changing character of the devices helps prevent the person's stomach from compensating for the implant, such as sometimes happens with static intragastric devices.
摘要翻译：描述了跨腹部肥胖症治疗装置及其相关操作方法，其占据胃内的空间和/或刺激胃壁。经腹肥胖治疗装置和相关方法旨在帮助患者保持健康的体重。器件的特征包括经皮插入和无侵入性手术，无相关患者的侵入性手术风险，无明显的患者不适。这些装置的使用寿命可能依赖于酸性胃内的长期生存能力，但意图持续一年或更长时间。这些装置具有在尺寸上变化的能力，并且希望是自动致动，因为它们使用内部电动机或致动器改变形状和/或体积。设备的变化特性有助于防止人的胃部补偿植入物，例如有时会发生静态胃内装置。

2. 发明申请

WO2012054410A3 INTRAGASTRIC IMPLANTS WITH MULTIPLE FLUID CHAMBERS 审中-公开
公开(公告)号：WO2012054410A3
公开(公告)日：2012-04-26
申请号：PCT/US2011/056605
申请日：2011-10-18
申请人： ALLERGAN, INC. , BABKES, Mitchell H. , DOMINGUEZ, Zachary P. , MUDD, Christopher S. , OLROYD, Craig , D'AUGUSTA, Jonathan M.
发明人： BABKES, Mitchell H. , DOMINGUEZ, Zachary P. , MUDD, Christopher S. , OLROYD, Craig , D'AUGUSTA, Jonathan M.
IPC分类号： A61F5/00 , A61B10/00
摘要： An intragastric obesity treatment implant promotes a feeling of satiety in the patient by contacting the insides of the stomach wall, reducing the space in the stomach, or otherwise reducing the amount of food consumed. One intragastric obesity treatment implant two inflatable balloons coupled via a flow restrictor through which fluid may flow in response to peristaltic motions of a patient's stomach. Additionally, one implant comprises a pumping chamber coupled to a reservoir, where the pumping chamber moves stomach fluids into the reservoir in response to peristaltic motions of the patient's stomach.

3. 发明申请

WO2010065649A1 INJECTION DEVICE 审中-公开
标题翻译：注射装置
公开(公告)号：WO2010065649A1
公开(公告)日：2010-06-10
申请号：PCT/US2009/066427
申请日：2009-12-02
申请人： ALLERGAN, INC. , TEZEL, Ahmet , MCNERNEY, Kevin , MUDD, Christopher, S. , STORIE, Blake, R. , MANDAROUX, Bastien
发明人： TEZEL, Ahmet , MCNERNEY, Kevin , MUDD, Christopher, S. , STORIE, Blake, R. , MANDAROUX, Bastien
IPC分类号： A61M5/34
CPC分类号： A61M5/347 , A61M5/3293 , A61M2210/04
摘要： An injection device (10) includes a syringe (12) having a body (14) with a piston (18) disposed therein with an open end along with a viscous fluid disposed in the body for injection by the piston. A needle assembly (26) is provided which includes a cannula (30) having a luer connection engageable with the syringe distal end with the luer connector including a hub. Mating engagement is provided by way of internal threads at the syringe distal end and external treads of a hub with a pitch sufficient to prevent detachment of the hub from the syringe distal end during ejection of the viscous fluid. In addition, a stepped cavity, disposed in the hub, further prevents detachment of the hub from the syringe distal end during ejection of the viscous fluid.
摘要翻译：注射装置（10）包括具有本体（14）的注射器（12），其具有设置在其中的活塞（18），开口端与设置在主体中用于由活塞注射的粘性流体连接。提供一种针组件（26），其包括套管（30），所述套管具有可与注射器远端接合的鲁尔连接件，鲁尔连接器包括轮毂。配合接合通过注射器远端的内螺纹和具有足以防止在排出粘性流体期间将轮毂从注射器远端分离的间距的毂的外胎面提供。此外，设置在轮毂中的阶梯式空腔进一步防止在排出粘性流体期间轮毂从注射器远端脱离。

4. 发明申请

WO2009073437A1 POLYSACCHARIDE GEL FORMULATION 审中-公开
标题翻译：多糖凝胶配方
公开(公告)号：WO2009073437A1
公开(公告)日：2009-06-11
申请号：PCT/US2008/084515
申请日：2008-11-24
申请人： ALLERGAN, INC. , STROUMPOULIS, Dimitrios , MUDD, Christopher, S. , TEZEL, Ahmet
发明人： STROUMPOULIS, Dimitrios , MUDD, Christopher, S. , TEZEL, Ahmet
IPC分类号： A61K8/60 , A61K8/73 , A61K8/04 , A61Q19/00 , A61Q19/08 , A61K9/10 , A61K31/738 , C08B37/00 , A61K9/00
CPC分类号： A61L27/26 , A61K8/042 , A61K8/492 , A61K8/60 , A61K8/602 , A61K8/676 , A61K8/678 , A61K8/73 , A61K8/731 , A61K8/735 , A61K8/736 , A61K31/715 , A61K31/717 , A61K31/721 , A61K31/727 , A61K31/728 , A61K31/737 , A61K31/738 , A61K47/183 , A61K47/26 , A61K47/36 , A61K47/38 , A61K47/42 , A61K2800/522 , A61L27/505 , A61Q19/08 , C08B37/0072 , C08J3/075 , C08J2305/08 , C08K5/053 , C08L5/08 , C08L2205/02
摘要： Described herein are polysaccharide gel formulations including at least one inhibitor of polysaccharide degradation and methods of making the same. The methods described herein involve the steps of providing at least one polysaccharide and incorporating at least one inhibitor of degradation into the polysaccharide. In some embodiments, the incorporating step comprises 1 ) mixing the at least one inhibitor with the at least one polysaccharide at a highly hydrated state thereby encapsulating the at least one inhibitor in a polysaccharide network, and 2) dehydrating the polysaccharide network thereby controlling release kinetics or final swell ratio. In another embodiment, the incorporating step comprises 1) encapsulating at least one inhibitor into a biocompatible or biodegradable vessel and 2) combining the polysaccharide and the vessel into a gel formulation. The polysaccharide gel formulations described herein can be used for a variety of cosmetic applications.
摘要翻译：本文描述的是多糖凝胶制剂，其包括至少一种多糖降解抑制剂及其制备方法。本文描述的方法包括提供至少一种多糖并将至少一种降解抑制剂并入多糖中的步骤。在一些实施方案中，掺入步骤包括：1）以高水合状态将至少一种抑制剂与至少一种多糖混合，从而将至少一种抑制剂包封在多糖网络中，以及2）使多糖网络脱水从而控制释放动力学或最终膨胀比。在另一个实施方案中，掺入步骤包括：1）将至少一种抑制剂包封在生物相容性或可生物降解的容器中，和2）将多糖和血管结合成凝胶制剂。本文所述的多糖凝胶制剂可用于各种化妆品应用。

5. 发明申请

WO2012054522A3 ANCHORED NON- PIERCING DUODENAL SLEEVE 审中-公开
标题翻译：锚定式非刺激式套管
公开(公告)号：WO2012054522A3
公开(公告)日：2012-07-05
申请号：PCT/US2011056765
申请日：2011-10-18
申请人： ALLERGAN INC , BABKES MITCHELL H , DOMINGUEZ ZACHARY P , MUDD CHRISTOPHER S
发明人： BABKES MITCHELL H , DOMINGUEZ ZACHARY P , MUDD CHRISTOPHER S
IPC分类号： A61F5/00
CPC分类号： A61F5/0079 , A61F5/0076
摘要： An intragastric implant for obesity treatment is disclosed. The device delays digestion by providing a duodenal sleeve, and may also slows gastric emptying by limiting flow through the pyloric sphincter. The implant includes an elongated axially-compressible duodenal sleeve having a non-tissue-piercing anchor on a proximal end sized to lodge within the duodenal bulb. The anchor may have oppositely-directed anchoring flanges to resists migration in both directions. The sleeve may also have barbed ribs to resist proximal movement back up into the stomach. A method of implant includes collapsing/compressing the device and transorally advancing it through the esophagus to be deployed within the duodenum. A dissolvable jacket may constrain the implant for delivery and naturally dissolve upon implant. Removal of the implant may occur in the reverse.
摘要翻译：公开了一种用于肥胖症治疗的胃内植入物。该装置通过提供十二指肠套管来延迟消化，并且还可以通过限制通过幽门括约肌的流动来减缓胃排空。植入物包括细长的可轴向压缩的十二指肠套管，其具有在近端上的非组织穿刺锚固件，其尺寸设置成保持在十二指肠球囊内。锚固件可以具有相反方向的锚固凸缘以抵抗两个方向上的迁移。套筒还可以具有倒钩肋，以抵抗近端移动回到胃中。一种植入物的方法包括塌缩/压缩装置并将其经过食道通过食管进行部署在十二指肠内。可溶解的护套可以限制植入物用于递送，并且在植入时自然地溶解。相反，可能会发生植入物的移除。

6. 发明申请

WO2012054522A2 ANCHORED NON-PIERCING DUODENAL SLEEVE AND DELIVERY SYSTEMS 审中-公开
标题翻译：锚定式非连接套管和输送系统
公开(公告)号：WO2012054522A2
公开(公告)日：2012-04-26
申请号：PCT/US2011/056765
申请日：2011-10-18
申请人： ALLERGAN, INC. , BABKES, Mitchell H. , DOMINGUEZ, Zachary P. , MUDD, Christopher S.
发明人： BABKES, Mitchell H. , DOMINGUEZ, Zachary P. , MUDD, Christopher S.
IPC分类号： A61F5/00
CPC分类号： A61F5/0079 , A61F5/0076
摘要： An intragastric implant for obesity treatment is disclosed. The device delays digestion by providing a duodenal sleeve, and may also slows gastric emptying by limiting flow through the pyloric sphincter. The implant includes an elongated axially-compressible duodenal sleeve having a non-tissue-piercing anchor on a proximal end sized to lodge within the duodenal bulb. The anchor may have oppositely-directed anchoring flanges to resists migration in both directions. The sleeve may also have barbed ribs to resist proximal movement back up into the stomach. A method of implant includes collapsing/compressing the device and transorally advancing it through the esophagus to be deployed within the duodenum. A dissolvable jacket may constrain the implant for delivery and naturally dissolve upon implant. Removal of the implant may occur in the reverse.
摘要翻译：公开了一种用于肥胖症治疗的胃内植入物。该装置通过提供十二指肠套管来延缓消化，并且还可以通过限制通过幽门括约肌的流动来减缓胃排空。植入物包括细长的可轴向压缩的十二指肠套管，其具有在近端上的非组织刺穿锚固件，其大小设置在十二指肠球囊内。锚固件可以具有相反方向的锚固凸缘以抵抗两个方向的迁移。套筒还可以具有倒钩肋，以抵抗近端移动回到胃中。一种植入物的方法包括塌缩/压缩装置，并将其经过食道通过其前端部署在十二指肠内。可溶解的护套可以限制植入物用于递送，并且在植入时自然地溶解。相反，可能会发生植入物的移除。

7. 发明申请

WO2009158145A2 INJECTION DEVICE FOR SOFT-TISSUE AUGMENTATION FILLERS, BIOACTIVE AGENTS AND OTHER BIOCOMPATIBLE MATERIALS IN LIQUID OR GEL FORM 审中-公开
标题翻译：用于软组织填充填料，生物剂和液体或凝胶形式中的其他生物成分材料的注射装置
公开(公告)号：WO2009158145A2
公开(公告)日：2009-12-30
申请号：PCT/US2009/045831
申请日：2009-06-01
申请人： ALLERGAN, INC. , MUDD, Christopher, S. , TEZEL, Ahmet
发明人： MUDD, Christopher, S. , TEZEL, Ahmet
IPC分类号： A61M5/20
CPC分类号： A61M5/2053 , A61B5/150129 , A61M5/19 , A61M5/20 , A61M5/24 , A61M5/2448 , A61M5/31575 , A61M5/422 , A61M5/427 , A61M5/46 , A61M39/24 , A61M2005/2006 , A61M2005/2411 , A61M2005/3125 , A61M2005/3126 , A61M2005/3128 , A61M2005/31588 , A61M2202/0007 , A61M2202/049 , A61M2202/09 , A61M2202/20 , A61M2205/19 , A61M2205/3569 , A61M2205/36 , A61M2205/3606 , A61M2205/502 , A61M2205/52 , A61M2205/586 , A61M2205/587 , A61M2205/6045 , A61M2205/6063 , A61M2205/8206 , A61M2205/8212 , A61M2205/8237 , A61M2205/8243 , A61M2210/04
摘要： Described herein are injection devices capable of automatically injecting substances into the soft tissue of a patient. The devices can inject low to high viscosity materials at predetermined, user selected injection rates, allowing the operator more control than a traditional syringe. The devices can allow mixing of more than one substance and/or reconstitution of a solid substance for injection. The injection devices described herein can allow the operator to easily inject one or more low to high viscosity liquid or gel soft-tissue augmentation fillers, one or more drugs, one or more other biocompatible materials, or combinations thereof.
摘要翻译：这里描述的是能够将物质自动注射到患者的软组织中的注射装置。这些装置可以以预定的用户选择的注射速率注入低至高粘度的材料，使得操作者比传统注射器更加控制。该装置可以允许多于一种物质的混合和/或用于注射的固体物质的重建。本文所述的注射装置可以允许操作者容易地注入一种或多种低至高粘度液体或凝胶软组织增强填料，一种或多种药物，一种或多种其它生物相容性材料或其组合。

8. 发明申请

WO2011084504A1 SYRINGE COMPRISING TWO PLUNGERS WITH LOCKING MEANS 审中-公开
标题翻译：包装两个枕头的锁紧装置
公开(公告)号：WO2011084504A1
公开(公告)日：2011-07-14
申请号：PCT/US2010/060553
申请日：2010-12-15
申请人： ALLERGAN, INC. , STROUMPOULIS, Dimitrios , MUDD, Christopher, S.
发明人： STROUMPOULIS, Dimitrios , MUDD, Christopher, S.
IPC分类号： A61M5/19 , A61M5/315 , A61F2/00
CPC分类号： A61M5/31501 , A61M5/19 , A61M5/31511 , A61M5/3158 , A61M5/31596 , A61M2005/31508 , A61M2005/31598
摘要： The syringe includes a syringe body (101) with a fluid chamber and with an extrusion opening (104) at the proximal end (401); a dividing wall disposed within the fluid chamber, defining a first fluid chamber (302) and a second fluid chamber (303), the first fluid chamber and the second fluid chamber in communication with the extrusion opening; a first plunger (102) disposed in a distal end of the first chamber, the first plunger including a first locking mechanism (402) configured to prevent the first plunger from sliding away from the proximal end of the syringe body, when the first plunger is in a first initial position and the second plunger is being depressed; and a second plunger disposed in a distal end of the second chamber, the second plunger including a second locking mechanism (402) configured to prevent the second plunger from sliding away from the proximal end of the syringe body when the second plunger is in a second initial position and the first plunger is being depressed.
摘要翻译：注射器包括具有流体室的注射器主体（101）和在近端（401）处的挤出开口（104）; 分隔壁，其设置在所述流体室内，限定第一流体室（302）和第二流体室（303），所述第一流体室和所述第二流体室与所述挤出口连通; 设置在所述第一腔室的远端中的第一柱塞（102），所述第一柱塞包括第一锁定机构（402），所述第一锁定机构构造成当所述第一柱塞为所述第一柱塞时，防止所述第一柱塞从所述注射器主体的近端滑离; 在第一初始位置和第二柱塞被压下; 以及设置在所述第二腔室的远端中的第二柱塞，所述第二柱塞包括第二锁定机构（402），所述第二锁定机构构造成当所述第二柱塞处于第二柱塞时，所述第二锁定机构被构造成防止所述第二柱塞从所述注射器主体的近端滑离初始位置和第一柱塞被压下。

9. 发明申请

WO2011071654A1 SLOTTED SYRINGE 审中-公开
标题翻译：缝制的SYRINGE
公开(公告)号：WO2011071654A1
公开(公告)日：2011-06-16
申请号：PCT/US2010/056304
申请日：2010-11-11
申请人： ALLERGAN, INC. , MUDD, Christopher S.
发明人： MUDD, Christopher S.
IPC分类号： A61M5/178 , A61M5/31
CPC分类号： A61M5/3137 , A61M5/3129 , A61M5/3135 , A61M5/31511 , A61M5/3158 , A61M2005/3139 , A61M2005/31518 , A61M2005/5006 , A61M2202/06
摘要： A syringe is disclosed. The syringe may include a syringe body (101) with a fluid chamber, the syringe body having a proximal end and a distal end, with an extrusion opening at the proximal end; a first slot (102) formed in the syringe body, starting near the proximal end of the syringe body and ending near the distal end of the syringe body; a first sleeve covering the first slot; a thumb grip, the thumb grip including a first slot guide disposed in the first slot, the thumb grip shaped to slide from a first position near the distal end of the syringe body toward a second position near the proximal end of the syringe body; and a plunger disposed in the fluid chamber of the syringe body, the plunger configured to move towards the proximal end of the syringe body in response to pressure applied by a user to the thumb grip, the plunger including a first plunger slot guide disposed in the first slot.
摘要翻译：公开了一种注射器。注射器可以包括具有流体室的注射器主体（101），注射器主体具有近端和远端，在近端具有挤出开口; 形成在注射器主体中的第一槽（102），从注射器主体的近端开始并在注射器主体的远端附近结束; 覆盖所述第一槽的第一套筒; 拇指手柄，包括设置在第一槽中的第一槽导向件，该拇指夹被成形为从注射器主体的远端附近的第一位置朝向靠近注射器本体的近端的第二位置滑动; 以及设置在所述注射器主体的流体室中的柱塞，所述柱塞构造成响应于由使用者施加到所述拇指把手的压力而朝向所述注射器本体的近端移动，所述柱塞包括设置在所述注射器主体中的第一柱塞狭槽引导件第一个插槽

10. 发明申请

WO2011059909A1 POLYSACCHARIDE GEL FORMULATION HAVING MULTI-STAGE BIOACTIVE AGENT DELIVERY 审中-公开
标题翻译：具有多阶段生物交换剂的多糖凝胶配方
公开(公告)号：WO2011059909A1
公开(公告)日：2011-05-19
申请号：PCT/US2010/055801
申请日：2010-11-08
申请人： ALLERGAN, INC. , STROUMPOULIS, Dimitrios , LESLIE, Dustin B. , MUDD, Christopher S. , TEZEL, Ahmet
发明人： STROUMPOULIS, Dimitrios , LESLIE, Dustin B. , MUDD, Christopher S. , TEZEL, Ahmet
IPC分类号： A61K8/60 , A61K8/73 , A61K8/04 , A61K8/34 , A61K9/10 , A61K47/36 , A61K47/10 , A61K47/26 , A61K31/728 , A61K31/738
CPC分类号： A61K8/042 , A61K8/492 , A61K8/60 , A61K8/602 , A61K8/676 , A61K8/678 , A61K8/73 , A61K8/731 , A61K8/735 , A61K8/736 , A61K9/0024 , A61K31/715 , A61K31/717 , A61K31/721 , A61K31/727 , A61K31/728 , A61K31/737 , A61K31/738 , A61K47/12 , A61K47/36 , A61K2800/522 , A61Q19/08 , C08B37/0072 , C08J3/075 , C08J3/12 , C08J3/128 , C08J3/24 , C08J2351/02 , C08K5/0025 , C08L1/02 , C08L5/04 , C08L5/08 , C08L5/10
摘要： Described herein are polysaccharide gel formulations including at least one inhibitor of polysaccharide degradation and methods of making the same. The methods described herein involve the steps of providing at least one polysaccharide and incorporating at least one inhibitor of degradation into the polysaccharide.
摘要翻译：本文描述的是多糖凝胶制剂，其包括至少一种多糖降解抑制剂及其制备方法。本文描述的方法包括提供至少一种多糖并将至少一种降解抑制剂并入多糖中的步骤。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式