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11. 发明申请

WO1995030169A1 STEREOGRAPHIC BOOK 审中-公开
公开(公告)号：WO1995030169A1
公开(公告)日：1995-11-09
申请号：PCT/US1995005411
申请日：1995-05-02
申请人： JONES, Charles, W.
IPC分类号： G02B27/22
CPC分类号： G02B27/22 , G02B27/2257
摘要： A stereographic book (10) includes a base portion (16), a plurality of pages (41) having text and stereographic imagery (44) thereon, and a fastener (36) for coupling the plurality of pages (41) to the base portion (16) about a page pivotal axis (40). The stereographic book (10) also includes a stereoscopic viewer (50) having a viewer body and a lens system (56), and a coupling section (52) formed integrally with the base portion (16) and the viewer body for pivotably coupling the stereoscopic viewer (50) to the base portion (16).
摘要翻译：立体书（10）包括基部（16），在其上具有文本和立体图像（44）的多页（41）和用于将多页（41）连接到基部（16）围绕页面枢转轴线（40）。立体书（10）还包括具有观看者主体和透镜系统（56）的立体观察器（50），以及与基部（16）和观察体一体地形成的耦合部分（52），用于可枢转地联接立体观察器（50）连接到基部（16）。

12. 发明申请

WO1995021070A1 CLUTCH CONTROL SYSTEM 审中-公开
标题翻译：离合器控制系统
公开(公告)号：WO1995021070A1
公开(公告)日：1995-08-10
申请号：PCT/GB1995000184
申请日：1995-01-30
申请人： AUTOMOTIVE PRODUCTS PLC , JARVIS, Roger, Porter , JONES, Charles, John
发明人： AUTOMOTIVE PRODUCTS PLC
IPC分类号： B60K41/02
CPC分类号： B60W10/06 , B60W10/02 , B60W10/04 , B60W30/18 , B60W30/1819 , B60W2510/0604 , B60W2710/022 , B60W2710/023 , F16H59/0217 , F16H2059/6823 , F16H2061/047 , F16H2312/02 , Y10T477/6422 , Y10T477/6437
摘要： A clutch control system for the automatic control of a motor vehicle clutch (14) which connects an engine (10) with a gearbox (12) under the control of a driver-operated gear ratio selector lever (24). The control system controls both initial clutch take-up on starting of the vehicle, clutch re-engagement following each ratio change, clutch disengagement on movement of the gear selector lever to change the operative ratio of the gearbox, and clutch disengagement on the coming to rest etc of the vehicle. Additionally the clutch control system includes an anti-baulking routine which is enabled if the gear selector lever (24) is in its neutral position and which when enabled allows engagement of the clutch (14) by increasing the engine speed (Ve) above an idle level.
摘要翻译：一种用于在驾驶员操作的变速比选择杆（24）的控制下自动控制机动车辆离合器（14）的离合器控制系统，其将发动机（10）与齿轮箱（12）相连接。控制系统控制车辆启动时的初始离合器吸收，每个比率变化后的离合器重新接合，变速杆移动时的离合器分离以改变变速箱的操作比，以及离合器脱离接合休息等车辆。另外，离合器控制系统包括防抱死程序，如果换档杆（24）处于其中立位置，则能够进行启用，并且当启动时，允许离合器（14）通过将发动机转速（Ve）增加到高于空转水平。

13. 发明申请

WO9514028A3 COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT AND PROPHYLAXIS OF BACTERIAL INFECTIONS 审中-公开
标题翻译：用于治疗和预防细菌感染的化合物和药物组合物
公开(公告)号：WO9514028A3
公开(公告)日：1995-06-15
申请号：PCT/US9413455
申请日：1994-11-18
申请人： UNIV WASHINGTON , SYMBICOM AB , HULTGREN SCOTT , KUEHN META , XU ZHENG , OGG DEREK , HARRIS MARK , LEPISTO MATTI , JONES CHARLES HAL , KIHLBERG JAN
发明人： HULTGREN SCOTT , KUEHN META , XU ZHENG , OGG DEREK , HARRIS MARK , LEPISTO MATTI , JONES CHARLES HAL , KIHLBERG JAN
IPC分类号： C12N15/09 , A61K31/165 , A61K31/18 , A61K31/43 , A61K31/545 , A61K31/65 , A61K31/70 , A61K31/7008 , A61K31/7028 , A61K38/00 , A61K45/00 , A61P1/00 , A61P31/04 , C07H1/00 , C07H5/06 , C07H15/04 , C07K5/06 , C07K9/00 , G01N33/569 , G01N33/68 , C07H15/203 , C07H23/00
CPC分类号： A61K31/7004 , C07H1/00 , G01N33/56911 , G01N33/68 , G01N2500/20 , Y10S435/849
摘要： Novel methods for the treatment and/or prophylaxis of diseases caused by tissue-adhering bacteria are disclosed. By interacting with periplasmic molecular chaperones it is achieved that the assembly of pili is prevented or inhibited and thereby the infectivity of the bacteria is diminished. Also disclosed are methods for screening for drugs as well as methods for the de novo design of such drugs, methods which rely on novel computer drug modelling methods involving an approximative calculation of binding free energy between macromolecules. Finally, novel pyranosides which are believed to be capable of interacting with periplasmic molecular chaperones are also disclosed.

14. 发明申请

WO2013036809A2 CASE FOR STORING VIALS 审中-公开
标题翻译：案例储存小米
公开(公告)号：WO2013036809A2
公开(公告)日：2013-03-14
申请号：PCT/US2012/054227
申请日：2012-09-07
申请人： J.L. CLARK, INC. , HANNAH, Detrick D. , JONES, Charles R.
发明人： HANNAH, Detrick D. , JONES, Charles R.
IPC分类号： B65D85/42
CPC分类号： B65D85/42 , B65D25/103 , B65D81/3832
摘要： In one embodiment, a case for storing vials comprising a cover, a container bottom, and top and bottom tray portions is provided. The container bottom provides a storage cavity in which vials can be stored. The cover is movable relative to the container bottom to provide selective access to the storage cavity. The top tray portion defines a first top surface including a plurality of top tray slots. Each top tray slot is configured for receiving a first portion of a vial. The top tray portion defines at least a portion of a first cavity storing a first cooling material therein. The bottom tray portion defines a second top surface including a plurality of bottom tray slots. Each bottom tray slot is configured for receiving a second portion of a vial. The bottom tray portion defines at least a portion of a second cavity storing a second cooling material therein.
摘要翻译：在一个实施例中，提供了用于存储包括盖子，容器底部以及顶部和底部托盘部分的小瓶的壳体。容器底部提供储存腔，小瓶可以储存在该储存腔中。盖可相对于容器底部移动以提供对储存腔的选择性入口。顶部托盘部分限定包括多个顶部托盘槽的第一顶部表面。每个顶部托盘槽被构造成用于接收小瓶的第一部分。顶部托盘部分限定其中存储第一冷却材料的第一腔体的至少一部分。底部托盘部分限定包括多个底部托盘狭槽的第二顶部表面。每个底部托盘槽被构造成用于接收小瓶的第二部分。底部托盘部分限定在其中存储第二冷却材料的第二腔体的至少一部分。

15. 发明申请

WO2012094249A3 AUTOMATED PICK AND STOW SYSTEM 审中-公开
标题翻译：自动拍摄和展示系统
公开(公告)号：WO2012094249A3
公开(公告)日：2012-11-01
申请号：PCT/US2011068137
申请日：2011-12-30
申请人： JACK MAX LLC , JONES CHARLES A , ORTNER EARL
发明人： JONES CHARLES A , ORTNER EARL
IPC分类号： B65G1/12 , B65G1/127
CPC分类号： B65G1/127
摘要： A pick and stow system includes a conveyor system having a plurality of interconnected modules forming a continuous conveyor, each module having a first side and a second side and each configured for forming a shelf on both the first side and the second side. The system also includes a conveyor driver coupled with the conveyor and configured for driving the conveyor, thereby presenting one of the plurality of modules at a loading location for loading or removing an item onto or from the shelf of the module. In some embodiments, a first wheel and a second wheel are each configured for coupling with each of the plurality of modules of the conveyor as the conveyor is driven about the first wheel and the second wheel, such that the conveyor has two substantially vertical sections and a curved section at each of the first and second wheels.
摘要翻译：拾取和收起系统包括具有形成连续输送机的多个互连模块的输送机系统，每个模块具有第一侧面和第二侧面，并且每个模块构造成用于在第一侧面和第二侧面上形成搁板。该系统还包括与输送机联接并被配置为用于驱动输送机的输送机驱动器，从而在装载位置处呈现多个模块中的一个，用于将物品装载或从模块的搁板上取出。在一些实施例中，当传送器围绕第一轮和第二轮被驱动时，第一轮和第二轮分别构造成与输送机的多个模块中的每一个联接，使得输送机具有两个基本垂直的部分，在第一和第二轮的每一个处的弯曲部分。

16. 发明申请

WO2005051893A2 VITAMIN D RECEPTOR MODULATORS 审中-公开
标题翻译：维生素D受体调节剂
公开(公告)号：WO2005051893A2
公开(公告)日：2005-06-09
申请号：PCT/US2004/037182
申请日：2004-11-16
申请人： ELI LILLY AND COMPANY , BUNEL, Emilio, Enrique , GAJEWSKI, Robert, Peter , JONES, Charles, David , LU, Jianliang , NAGPAL, Sunil , MA, Tianwei , YEE, Ying, Kwong
发明人： BUNEL, Emilio, Enrique , GAJEWSKI, Robert, Peter , JONES, Charles, David , LU, Jianliang , NAGPAL, Sunil , MA, Tianwei , YEE, Ying, Kwong
IPC分类号： C07C235/00
CPC分类号： C07C235/42 , C07C65/19 , C07C69/92 , C07C235/84 , C07C2601/08 , C07C2601/14 , C07D257/04 , C07D257/06
摘要： The present invention relates to novel, non-secosteroidal, hydroxyl substituted, carbon- linked diaryl compounds with vitamin D receptor (VDR) modulating activity that are less hypercalcemic than 1?,25 dihydroxy vitamin D3. These compounds are useful for treating bone disease and psoriasis.
摘要翻译：本发明涉及具有维生素D受体（VDR）调节活性的新颖的非甾体，羟基取代的碳键二芳基化合物，其比1α，25二羟基维生素D3低钙血红素。这些化合物可用于治疗骨病和牛皮癣。

17. 发明申请

WO1997041851A1 BENZOTHIOPHENES, FORMULATIONS CONTAINING SAME, AND METHODS 审中-公开
标题翻译：苯并噻唑类，含有它们的制剂和方法
公开(公告)号：WO1997041851A1
公开(公告)日：1997-11-13
申请号：PCT/US1997007547
申请日：1997-05-05
申请人： ELI LILLY AND COMPANY , CLAY, Michael, P. , FROLIK, Charles, A. , JONES, Charles, D. , LINDSTROM, Terry, D.
发明人： ELI LILLY AND COMPANY
IPC分类号： A61K31/34
CPC分类号： C07D333/56
摘要： This invention provides compounds of formula (I) wherein R is hydrogen, hydroxy, C1-C4 alkoxy, -OCOO(C1-C6 alkyl), -OCO(C1-C6 alkyl), -OCOAr wherein Ar is phenyl or optionally substituted phenyl, -OSO2 (C4-C6 straight chain alkyl), or -OSO3H; R is R , C1 or F; with the proviso that at least one of R or R is -OSO3H; R is 1-piperidinyl, 1-pyrrolidinyl, methyl-1-pyrrolidinyl, dimethyl-1-pyrrolidino, 4-morpholino, dimethylamino, diethylamino, diisopropylamino, or 1-hexamethyleneimino; and n is 2 or 3; or a pharmaceutically acceptable salt or solvate thereof. The present invention further relates to pharmaceutical compositions containing compounds of formula (I), optionally containing estrogen or progestin, and the use of such compounds, alone, or in combination with estrogen or progestin, for alleviating the symptoms of post-menopausal syndrome, particularly osteoporosis, cardiovascular related pathological conditions, and estrogen-dependent cancer. The compounds of the present invention also are useful for inhibiting uterine fibroid disease and endometriosis in women and aortal smooth muscle cell proliferation, particularly restenosis, in humans.
摘要翻译：本发明提供式（I）化合物，其中R 1是氢，羟基，C 1 -C 4烷氧基，-OCOO（C 1 -C 6烷基），-OCO（C 1 -C 6烷基），-OCOAr，其中Ar是苯基或任选地取代的苯基，-OSO 2（C 4 -C 6直链烷基）或-OSO 3 H; R 2是R 1，C 1或F; 条件是R 1或R 2中的至少一个是-OSO 3 H; R 3是1-哌啶基，1-吡咯烷基，甲基-1-吡咯烷基，二甲基-1-吡咯烷子基，4-吗啉代，二甲基氨基，二乙基氨基，二异丙基氨基或1-六亚甲基亚氨基; n为2或3; 或其药学上可接受的盐或溶剂合物。本发明还涉及包含式（I）化合物，任选地含有雌激素或孕激素的药物组合物，以及这些化合物单独或与雌激素或孕激素组合用于减轻绝经后综合征症状的用途，特别是骨质疏松症，心血管相关病理状况和雌激素依赖性癌症。本发明的化合物还可用于抑制妇女子宫肌瘤和子宫内膜异位症以及主动脉平滑肌细胞增殖，特别是人类的再狭窄。

18. 发明申请

WO1996017351A1 LIGHTWEIGHT SOLID-CORE VIDEO CASSETTE CARTRIDGE 审中-公开
标题翻译：轻巧的固体视频卡西尔盒
公开(公告)号：WO1996017351A1
公开(公告)日：1996-06-06
申请号：PCT/US1995014890
申请日：1995-11-15
申请人： V-LITE CORPORATION , KRANTZ, Kermit, T. , JONES, Charles, R., Jr.
发明人： V-LITE CORPORATION
IPC分类号： G11B23/087
CPC分类号： G11B23/08785 , G11B23/08728
摘要： A lightweight solid-core video cassette cartridge (10) includes a cartridge shell and a solid core structural member (16). The cartridge shell includes spaced apart top and bottom panels (12, 14) which define an interior hollow chamber therebetween. A pair of video tape reels (18, 20) are positioned within the hollow chamber for winding video tape. The solid core structural member (16) is provided for maintaining the spaced relationship of the top and bottom panels (12, 14). The solid core structural member is formed of styrofoam, cardboard or synthetic resin. The solid core structural member (16) and the video tape reels (18, 20) fill substantially the entire volume of the cartridge shell hollow chamber.
摘要翻译：一种轻巧的实心盒式磁带（10）包括一个盒壳和一个实芯结构件（16）。盒壳包括间隔开的顶部和底部面板（12,14），其在它们之间限定内部中空室。一对录像带（18,20）位于中空室内，用于卷绕录像带。实心芯结构构件（16）被设置用于保持顶板和底板（12,14）的间隔关系。实芯结构件由聚苯乙烯泡沫塑料，纸板或合成树脂制成。固体芯结构构件（16）和录像带卷轴（18,20）基本上填充盒壳中空室的整个体积。

19. 发明申请

WO1995022014A1 CLUTCH CONTROL SYSTEM 审中-公开
标题翻译：离合器控制系统
公开(公告)号：WO1995022014A1
公开(公告)日：1995-08-17
申请号：PCT/GB1995000267
申请日：1995-02-10
申请人： AUTOMOTIVE PRODUCTS PLC , JONES, Charles, John , KENNEDY, Ian, Duncan
发明人： AUTOMOTIVE PRODUCTS PLC
IPC分类号： F16D48/08
CPC分类号： F16D48/08 , B60W2510/0638 , B60W2540/16 , B60W2710/023 , F16D48/066 , F16D48/068 , F16D2500/1026 , F16D2500/30426 , F16D2500/3067 , F16D2500/30806 , F16D2500/30816 , F16D2500/31466 , F16D2500/50224 , F16D2500/50296 , F16D2500/5124 , F16D2500/70235 , F16D2500/7041 , F16D2500/70454 , F16D2500/7101 , F16D2500/7109 , Y10T477/689 , Y10T477/6934 , Y10T477/75
摘要： A clutch control system for the automatic control of a motor vehicle clutch which connects an engine with a gearbox under the control of a driver operated gear ratio selector lever. The control system controls both initial clutch take-up on starting of the vehicle, clutch re-engagement following each ratio change, clutch disengagement on movement of the gear selector lever to change the operative ratio of the gearbox, and clutch disengagement on the coming to rest of the vehicle. The clutch control system also warms (50, c) the operator if he attempts to drive away in a designated non take-up gear or in any gear in a predetermined abusive manner and may be arranged to promote rapid engagement or disengagement of the clutch in certain abusive conditions to reduce energy generation in the clutch.
摘要翻译：一种用于在驾驶员操作的变速比选择杆的控制下将发动机与变速箱连接的机动车辆离合器的自动控制的离合器控制系统。控制系统控制车辆启动时的初始离合器吸收，每个比率变化后的离合器重新接合，变速杆移动时的离合器分离以改变变速箱的操作比，以及离合器脱离接合其余车辆。如果离合器控制系统试图以指定的非卷绕装置或任何齿轮以预定的侮辱方式驾驶，那么离合器控制系统还会加热（50，c）操作员，并且可以设置成促进离合器的快速接合或脱离某些滥用条件来减少离合器中的能量产生。

20. 发明申请

WO1995014028A2 COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT AND PROPHYLAXIS OF BACTERIAL INFECTIONS 审中-公开
标题翻译：用于治疗和预防细菌感染的化合物和药物组合物
公开(公告)号：WO1995014028A2
公开(公告)日：1995-05-26
申请号：PCT/US1994013455
申请日：1994-11-18
申请人： WASHINGTON UNIVERSITY , SYMBICOM AKTIEBOLAG , HULTGREN, Scott , KUEHN, Meta , XU, Zheng , OGG, Derek , HARRIS, Mark , LEPISTO, Matti , JONES, Charles, Hal , KIHLBERG, Jan
发明人： WASHINGTON UNIVERSITY , SYMBICOM AKTIEBOLAG
IPC分类号： C07H15/203
CPC分类号： A61K31/7004 , C07H1/00 , G01N33/56911 , G01N33/68 , G01N2500/20 , Y02A50/481 , Y10S435/849
摘要： Novel methods for the treatment and/or prophylaxis of diseases caused by tissue-adhering bacteria are disclosed. By interacting with periplasmic molecular chaperones it is achieved that the assembly of pili is prevented or inhibited and thereby the infectivity of the bacteria is diminished. Also disclosed are methods for screening for drugs as well as methods for the de novo design of such drugs, methods which rely on novel computer drug modelling methods involving an approximative calculation of binding free energy between macromolecules. Finally, novel pyranosides which are believed to be capable of interacting with periplasmic molecular chaperones are also disclosed.
摘要翻译：公开了用于治疗和/或预防由组织粘附细菌引起的疾病的新方法。通过与周质分子伴侣相互作用，可以防止或抑制毛细血管的组装，从而减少细菌的感染性。还公开了用于筛选药物的方法以及用于从头设计这些药物的方法，这些方法依赖于涉及大分子之间的结合自由能的近似计算的新型计算机药物建模方法。最后，还公开了被认为能够与周质分子伴侣相互作用的新型吡喃糖苷。

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