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    • 93. 发明申请
    • MEDICAMENT DELIVERY DEVICE
    • 药物递送装置
    • WO2013178512A1
    • 2013-12-05
    • PCT/EP2013/060466
    • 2013-05-22
    • CAREBAY EUROPE LTD
    • BRUNNBERG, LennartOLSON, Stephan
    • A61M5/20A61M5/315
    • A61M5/2033A61M5/3157A61M2005/2013A61M2005/206A61M2005/2086
    • A medicament delivery device wherein a drive mechanism comprises a first resilient member 91 and a delay plunger rod assembly; wherein the delay plunger rod assembly comprises a proximal plunger 96, a distal plunger 90, a chamber 95 formed between the proximal and the distal plungers, an aperture, and delay means contained within the chamber; the distal plunger being positioned and configured in relation to a hold and release mechanism such that, as the drive mechanism exerts a pressure on the medicament container, the distal plunger acts against the delay means whereby a release of a signal generating member is delayed after the release of the drive mechanism to allow remaining contents of medicament in a medicament container to be completely expelled before the signal generating member is released.
    • 一种药物输送装置,其中驱动机构包括第一弹性构件91和延迟柱塞杆组件; 其中延迟柱塞杆组件包括近端柱塞96,远端柱塞90,形成在近端和远端柱塞之间的腔室95,孔和容纳在腔室内的延迟装置; 所述远端柱塞相对于保持和释放机构定位和构造,使得当所述驱动机构对所述药物容器施加压力时,所述远端柱塞对着所述延迟装置起作用,由此在所述信号发生构件的释放之后被延迟 释放驱动机构以允许药物容器内的药物的剩余内容物在释放信号产生元件之前被完全排出。
    • 94. 发明申请
    • INJEKTIONSVORRICHTUNG MIT EINEM DOSIERGLIED UND EINER VORGESPANNTEN AUSSCHÜTTFEDER
    • 具有计量和预应力分配弹簧注射装置
    • WO2013144021A1
    • 2013-10-03
    • PCT/EP2013/056095
    • 2013-03-22
    • TECPHARMA LICENSING AG
    • SCHENKER, SusanneSTREIT, Ursina
    • A61M5/315
    • A61M5/3155A61M5/20A61M5/31501A61M5/31553A61M5/31563A61M5/3157A61M5/31583A61M5/31593A61M2005/2026A61M2005/2407A61M2005/3126A61M2205/581A61M2205/582
    • Antriebs- und Dosiervorrichtung für eine Injektionsvorrichtung zur Verabreichung eines flüssigen Produkts, insbesondere eines Medikaments, wobei mit der Antriebs- und Dosiervorrichtung eine zu verabreichende Produktdosis einstellbar ist, umfassend: a) ein Gehäuse (4), b) ein Dosisanzeigeelement (10), über dessen Umfang eine Dosisskala (10b) angeordnet ist, c) eine Zeigeeinrichtung (4d) und ein insbesondere vom Verwender der Antriebs- und Dosiervorrichtung greifbares Dosierglied (3), wobei zur Einstellung der zu verabreichenden Dosis durch Drehung des Dosierglieds (3) relativ zu der Zeigeeinrichtung (4d) das Dosisanzeigeelement (10) relativ zu der Zeigeeinrichtung (4d) und um eine Drehachse (L) drehbar, insbesondere schraubbar ist und mittels der Zeigeeinrichtung (4d) ein Wert der Dosisskala (10b) ablesbar ist, welcher der eingestellten Dosis entspricht, d) ein Lagerelement (9), mit dem das Dosisanzeigeelement (10) in einem Eingriff ist, der die Dreh- oder Schraubbewegung des Dosisanzeigeelements (10) relativ zu der Zeigeeinrichtung (4d) bewirkt, dadurch gekennzeichnet, dass e) das Lagerelement (9) zusammen mit dem Dosisanzeigeelement (10) relativ zu dem Gehäuse (4) und entlang der Drehachse (L) verschiebbar ist.
    • 驱动和计量装置用于注射装置用于施用流体的产品,特别是药剂,其中一种产品被施用剂量被连接至驱动器和计量调节的,其包括:a)壳体(4)中,b)的剂量显示元件(10),用 其中一个剂量刻度(10B)布置在所述周缘,c)一种指向装置(4D),并且通过驱动器和计量定量给料件(3)的用户,尤其是有形其中,对于所述剂量通过定量给料件的旋转被施用调节(3)相对于所述 指向装置(4D)的剂量显示元件(10)相对于所述指示装置(4D),并绕旋转轴线(L)旋转,特别是可以拧,并且由指示设备(4D)的剂量刻度(10b)中的一个值的装置可以对应于所述设定剂量被读取 ,D)的轴承元件(9),这是在Dosisa的接合,旋转或螺旋运动剂量指示器元件(10) nzeigeelements(10)相对于所述指示装置(4D),其特征在于,E)的支承元件(9)(连同剂量指示器元件10)相对于所述壳体(4)和(沿旋转轴线L)是可移动的。
    • 95. 发明申请
    • MEDICAMENT DELIVERY DEVICE
    • 药物递送装置
    • WO2013077800A1
    • 2013-05-30
    • PCT/SE2012/051283
    • 2012-11-21
    • SHL GROUP AB
    • OLSON, Stephan
    • A61M5/315A61M5/20A61M5/24A61M5/28
    • A61M5/31568A61M5/20A61M5/2033A61M5/24A61M5/31501A61M5/3157A61M5/31586A61M2205/581A61M2205/582A61M2205/583
    • The present invention relates to an Injection device comprising a housing (2, 3, 4, 5), a container holder (10), said container holder (10) being configured for accommodating a medicament container (12) having a needle (13) attached to one end thereof and a stopper sealingly and slidable arranged inside said medicament container (12) at the other end thereof, a drive unit comprising a plunger rod (60) and plunger drive means (50, 70), said drive unit further comprising a first energy accumulating member (40), wherein said plunger drive means (50, 70) is operationally associated with said first energy accumulating member (40), and an injection indication mechanism (182, 204, 212), wherein the injection indication mechanism (182, 204, 212) comprises a tactile signalling element (204, 212) and a drive mechanism (182) for driving said tactile signalling member, said drive mechanism (182) being coupled to said plunger drive means (50, 70).
    • 本发明涉及一种包括壳体(2,3,4,5),容器保持器(10)的注射装置,所述容器保持器(10)构造成容纳具有针头(13)的药物容器(12) 附着于其一端和在其另一端密封且滑动地布置在所述药物容器(12)的内部的驱动单元,包括柱塞杆(60)和柱塞驱动装置(50,70)的驱动单元,所述驱动单元还包括 第一能量存储构件(40),其中所述柱塞驱动装置(50,70)在操作上与所述第一能量存储构件(40)相关联,以及注射指示机构(182,204,212),其中所述注射指示机构 (182,204,212)包括用于驱动所述触觉信号构件的触觉信号元件(204,212)和驱动机构(182),所述驱动机构(182)联接到所述柱塞驱动装置(50,70)。
    • 99. 发明申请
    • AUTO-INJECTOR
    • 自动注射器
    • WO2012110579A1
    • 2012-08-23
    • PCT/EP2012/052648
    • 2012-02-16
    • SANOFI-AVENTIS DEUTSCHLAND GMBHBRERETON, Simon FrancisKEMP, ThomasBURNELL, RosieEKMAN, Matthew
    • BRERETON, Simon FrancisKEMP, ThomasBURNELL, RosieEKMAN, Matthew
    • A61M5/20A61M5/315A61M5/32A61M5/50
    • A61M5/3158A61M5/2033A61M5/31501A61M5/31511A61M5/3157A61M5/3202A61M5/3204A61M5/3257A61M5/326A61M5/46A61M5/5086A61M2005/2013A61M2005/206A61M2005/208A61M2005/3247A61M2205/581A61M2205/582F04C2270/0421Y10T403/32501
    • The invention relates to an auto-injector (1) for administering a dose of a liquid medicament (M), comprising: -an elongate tubular case (12), -a carrier subassembly comprising a tubular carrier (7) slidably arranged inside the case (12), the carrier (7) adapted to contain a syringe (3) with a hollow injection needle (4), a drive spring (8) and a plunger (9) for forwarding load of the drive spring (8) to a stopper (6) of the syringe (3), wherein the syringe (3) is lockable for joint axial translation with the carrier (7), wherein the drive spring (8) acts between the carrier (7) and the plunger (9), wherein the plunger (9) in an initial state is locked to the carrier (7) by a ramped engagement to the carrier (7) and by being prevented from rotating out of this ramped engagement depending on a relative longitudinal position of the carrier (7) in the case (12), wherein the plunger (9) is arranged to be released for rotating out of the ramped engagement upon the needle (4) reaching at least nearly a predefined injection depth on translation of the carrier (7) in the proximal direction (P) for advancing the needle (4) beyond a proximal end of the auto-injector (1).
    • 本发明涉及一种用于给药剂量的液体药物(M)的自动注射器(1),包括: - 细长的管状壳体(12), - 载体子组件,其包括可滑动地布置在壳体内的管状载体(7) (12),所述载体(7)适于容纳具有中空注射针(4)的注射器(3),驱动弹簧(8)和用于将所述驱动弹簧(8)的载荷传递到 所述注射器(3)的止动器(6),其中所述注射器(3)可锁定用于与所述承载件(7)的关节轴向平移,其中所述驱动弹簧(8)作用在所述托架(7)和所述柱塞(9)之间, ,其中处于初始状态的所述柱塞(9)通过与所述托架(7)的倾斜接合而被锁定到所述托架(7),并且根据所述托架的相对纵向位置被阻止从所述倾斜接合中旋转出 如图7所示,在(12)的情况下,其中柱塞(9)被布置成被释放以在针(4)到达lea处的倾斜接合中旋转 在近端方向(P)上平移载体(7)几乎预定的注射深度,用于将针(4)推进超过自动注射器(1)的近端。
    • 100. 发明申请
    • AUTO-INJECTOR
    • 自动注射器
    • WO2012110575A1
    • 2012-08-23
    • PCT/EP2012/052643
    • 2012-02-16
    • SANOFI-AVENTIS DEUTSCHLAND GMBHBRERETON, Simon FrancisKEMP, ThomasBURNELL, RosieEKMAN, Matthew
    • BRERETON, Simon FrancisKEMP, ThomasBURNELL, RosieEKMAN, Matthew
    • A61M5/20A61M5/32
    • A61M5/3158A61M5/2033A61M5/31501A61M5/31511A61M5/3157A61M5/3202A61M5/3204A61M5/3257A61M5/326A61M5/46A61M5/5086A61M2005/2013A61M2005/206A61M2005/208A61M2005/3247A61M2205/581A61M2205/582F04C2270/0421Y10T403/32501
    • An Auto-injector (1) for administering a dose of a liquid medicament (M) comprises: - an elongate case (12), - a carrier subassembly comprising a tubular carrier (7) slidably arranged inside the case (12), the carrier (7) adapted to contain a syringe (3) with a hollow injection needle (4), a drive spring (8) and a plunger (9) for forwarding load of the drive spring (8) to a stopper (6) of the syringe (3), wherein the syringe (3) is lockable for joint axial translation with the carrier (7), - a control spring (19) arranged around the carrier (7) for translating the carrier (7) in a proximal direction (P) for advancing the needle (4) beyond a proximal end of the auto-injector (1), - a trigger button (13) for releasing the control spring (19) on actuation. The drive spring (8) biases the plunger (9) in the proximal direction (P) against the carrier (7). At least one resilient arm (15) is arranged on either the carrier (7) or the plunger (9) and in a ramped engagement to the other of the carrier (7) or the plunger (9) so as to disengage them under load of the drive spring (8). A peg (14) is arranged to be coupled to the case (12) at least after actuation of the trigger button (13) so as to be positioned to support the resilient arm (15) preventing disengagement of the carrier (7) from the plunger (9) and thus release of the drive spring (8) when the carrier (7) is in a distal position. The peg (14) is arranged to remain in position when the carrier (7) is translated for advancing the needle (4) so as to pull the resilient arm (15) away from the peg (14) thus allowing deflection of the resilient arm (15) due to the ramped engagement under load of the drive spring (8) for disengaging the plunger (9) from the carrier (7) and releasing the drive spring (8) for drug delivery when the carrier (7) has reached a predefined position during needle advancement.
    • 一种用于施用剂量的液体药物(M)的自动注射器(1)包括: - 细长壳体(12), - 载体子组件,其包括可滑动地布置在所述壳体(12)内的管状载体(7),所述载体 (7),其适于容纳具有中空注射针(4)的注射器(3),驱动弹簧(8)和用于将所述驱动弹簧(8)的载荷传递到所述驱动弹簧的止动件(6)的活塞(9) 注射器(3),其中所述注射器(3)可锁定用于与所述载体(7)的关节轴向平移; - 控制弹簧(19),布置在所述载体(7)周围,用于在所述载体(7)的近端方向 P),用于将针(4)推进超过自动注射器(1)的近端; - 触发按钮(13),用于在致动时释放控制弹簧(19)。 驱动弹簧(8)将柱塞(9)沿近端方向(P)偏压在托架(7)上。 至少一个弹性臂(15)布置在载体(7)或柱塞(9)上,并且与载体(7)或柱塞(9)中的另一个倾斜接合,以便在载荷 的驱动弹簧(8)。 至少在触发按钮(13)的致动之后,销钉(14)被布置成联接到壳体(12),以便定位成支撑弹性臂(15),防止承载件(7)脱离 柱塞(9),从而当托架(7)处于远端位置时释放驱动弹簧(8)。 当托架(7)被平移以使针(4)前进时,钉(14)被布置成保持就位,以便将弹性臂(15)拉离钉(14),从而允许弹性臂 (8)的负载下由于斜拉接合而使柱塞(9)与载体(7)脱离并释放驱动弹簧(8)以用于当载体(7)达到 提针期间预定位置。