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91. 发明申请

WO2013019994A3 HEMODIALYSIS SYSTEM HAVING A FLOW PATH WITH A CONTROLLED COMPLIANT VOLUME 审中-公开
标题翻译：具有控制合格体积的流路的血液透析系统
公开(公告)号：WO2013019994A3
公开(公告)日：2013-04-25
申请号：PCT/US2012049398
申请日：2012-08-02
申请人： MEDTRONIC INC , KELLY THOMAS D , LYU SUPING , PUDIL BRYANT J , MEYER THOMAS E
发明人： KELLY THOMAS D , LYU SUPING , PUDIL BRYANT J , MEYER THOMAS E
IPC分类号： A61M1/34 , A61M1/16 , A61M1/38
CPC分类号： A61M1/3482 , A61M1/1696 , A61M2202/0021 , A61M2202/0413
摘要： Systems and methods for the performance of kidney replacement therapy having or using a dialyzer, control components, sorbent cartridge and fluid reservoirs configured to be of a weight and size suitable to be worn or carried by an individual requiring treatment are disclosed. The system for performing kidney replacement therapy has a controlled compliance dialysis circuit, where a control pump controls the bi-directional movement of fluid across a dialysis membrane. The dialysis circuit and an extracorporeal circuit for circulating blood are in fluid communication through the dialysis membrane. The flux of fluid moving between the extracorporeal circuit and the dialysis circuit is modified by the rate at which the control pump is operating such that a rate of ultrafiltration and convective clearance can be controlled. The system provides for the monitoring of an inlet and outlet conductivity of the sorbent cartridge to provide a facility to quantify or monitor the removal of urea by the sorbent cartridge.
摘要翻译：公开了用于执行肾脏替代疗法的系统和方法，其具有或使用透析器，控制组件，吸附剂盒和流体储存器，其被配置为适于被需要治疗的个体穿戴或携带的重量和尺寸。用于执行肾脏替代治疗的系统具有受控的依从性透析电路，其中控制泵控制流体穿过透析膜的双向运动。透析电路和用于循环血液的体外循环通过透析膜流体连通。在体外循环和透析回路之间移动的流体通量由控制泵运行的速率改变，从而可以控制超滤速率和对流间隙。该系统提供对吸附剂盒的入口和出口导电性的监测，以提供量化或监测吸附剂盒去除尿素的设施。

92. 发明申请

WO2013008168A1 DUAL CHAMBER BLOOD RESERVOIR 审中-公开
标题翻译：双室血液储存
公开(公告)号：WO2013008168A1
公开(公告)日：2013-01-17
申请号：PCT/IB2012/053497
申请日：2012-07-09
申请人： SORIN GROUP ITALIA S.R.L. , SILVESTRI, Claudio , TOMMASI, Gabriele
发明人： SILVESTRI, Claudio , TOMMASI, Gabriele
IPC分类号： A61M1/36
CPC分类号： A61M1/3638 , A61M1/1698 , A61M1/3627 , A61M1/3632 , A61M1/3666 , A61M2202/0413 , A61M2205/75
摘要： A blood reservoir (24; 25) may be used in combination with other elements such as a heart lung machine (HLM)(12), oxygenator(14), heat exchanger, arterial filter and the like to form an extracorporeal blood circuit (10) that may be employed in a procedure such as a bypass procedure. The blood reservoir (24; 25) may be configured to receive, filter and store blood from a number of sources including vent blood (from within the heart), venous blood (from a major vein), purge blood (from a sampling line) and cardiotomy or suction blood (from the surgical field).
摘要翻译：血液储存器（24; 25）可以与诸如心肺机（HLM）（12），氧合器（14），热交换器，动脉过滤器等其他元件组合使用，以形成体外血液回路），其可以在诸如旁路过程的过程中使用。血液储存器（24; 25）可以构造成接收，过滤和储存来自多个来源的血液，包括排出血液（来自心脏内），静脉血（来自主静脉），清除血液（来自取样管线）和心脏切开术或吸血（来自外科手术领域）。

93. 发明申请

WO2009072006A3 A CENTRIFUGE FOR SEPARATING A SAMPLE INTO AT LEAST TWO COMPONENTS 审中-公开
标题翻译：将样品分离成至少两个组分的离心机
公开(公告)号：WO2009072006A3
公开(公告)日：2009-08-06
申请号：PCT/IB2008003845
申请日：2008-12-08
申请人： MILTENYI BIOTEC GMBH , MILTENYI STEFAN , SCHIMMELPFENNIG WINFRIED , LANTOW HOLGER , NEUSCHAEFER ELMAR NIKLAS , BIEHL MARTIN , KABAHA EIAD , SCHULZ JUERGEN
发明人： MILTENYI STEFAN , SCHIMMELPFENNIG WINFRIED , LANTOW HOLGER , NEUSCHAEFER ELMAR NIKLAS , BIEHL MARTIN , KABAHA EIAD , SCHULZ JUERGEN
IPC分类号： B04B5/04 , B04B13/00 , G01N15/04
CPC分类号： G01N33/58 , A61M1/0209 , A61M1/3618 , A61M1/3633 , A61M1/3679 , A61M1/3692 , A61M1/3693 , A61M1/3696 , A61M2202/0071 , A61M2202/0413 , A61M2202/0427 , A61M2202/10 , B01D15/3809 , B01D15/3885 , B01D21/26 , B03C1/002 , B03C1/027 , B03C1/032 , B03C1/0332 , B03C1/0335 , B03C1/034 , B03C1/288 , B03C2201/18 , B03C2201/26 , B04B1/12 , B04B5/00 , B04B5/04 , B04B5/0442 , B04B5/10 , B04B7/08 , B04B13/00 , B04B2005/0464 , B04B2013/006 , C12M23/28 , C12M33/10 , C12M41/48 , C12M47/04 , C12N5/0636 , C12N5/0646 , C12N5/0647 , C12N5/0669 , G01N35/0098 , G01N2333/70596
摘要： The invention relates to a centrifuge for separating a sample into at least two components, comprising a chamber for receiving a sample to be centrifuged. According to the invention, the centrifuge further comprises a means for controlling the progress of the sample separation is located at the chamber.
摘要翻译：本发明涉及一种用于将样品分离成至少两个组分的离心机，包括用于接收要离心的样品的室。根据本发明，离心机还包括用于控制样品分离进度位于腔室的装置。

95. 发明申请

WO2007131611A3 METHOD FOR FILLING AND RINSING A SET OF BLOOD LINES 审中-公开
标题翻译：方法填充和冲洗血液管组的
公开(公告)号：WO2007131611A3
公开(公告)日：2008-01-10
申请号：PCT/EP2007003767
申请日：2007-04-27
申请人： FRESENIUS MEDICAL CARE DE GMBH , FISCHER MAX
发明人： FISCHER MAX
IPC分类号： A61M1/36 , A61M1/34
CPC分类号： A61M1/3649 , A61M1/1601 , A61M1/1603 , A61M1/267 , A61M1/3431 , A61M1/3627 , A61M1/3643 , A61M1/3644 , A61M1/3647 , A61M2202/0413 , A61M2205/33 , A61M2205/3337 , A61M2205/50
摘要： The invention relates to a method for filling and rinsing a set of blood lines, comprising a pump segment for a blood pump, an arterial line connected to an input of a dialysis machine and a venous line connected to the output of a dialysis machine, by means of a substitute line. Said method comprises the steps of connecting the arterial line to the venous line and connecting both lines to a rinse port, connecting the substitute line to a substitute port, opening the rinse port, filling the arterial and venous line, rinsing the arterial and venous line, closing the rinse port, circulating the substitute in the circuit of arterial line, dialysis machine, and venous line by means of the blood pump, characterised in that the filling and/or rinsing of the venous and the arterial line occurs simultaneously wherein substitute is introduced from the substitute line. The invention further relates to a set of blood lines.
摘要翻译：本发明涉及一种用于填充和血液管道组，其包括用于血液泵的泵送段，连接到动脉线路的输入的透析器和装置，连接到透析器的静脉线的输出的潮红，通过代替物管线的方法。它包括动脉线路连接到静脉管路，和连接这两条线与冲洗端口，具有代替物端口连接代替物，打开冲洗端口，填充所述动脉和静脉管线，冲洗步骤动脉和静脉线，关闭冲洗端口，在动脉管线，通过血液泵的透析器和静脉线路的循环中循环的代替物，且其特征在于：所述动脉和静脉线路的同时，填充物和/或漂洗，由此置换从置换提供。本发明还涉及一种血液管道组。

96. 发明申请

WO2007131611A2 VERFAHREN ZUR FÜLLUNG UND SPÜLUNG EINES BLUTSCHLAUCHSATZES 审中-公开
标题翻译：方法填充和冲洗血液管组的
公开(公告)号：WO2007131611A2
公开(公告)日：2007-11-22
申请号：PCT/EP2007/003767
申请日：2007-04-27
申请人： FRESENIUS MEDICAL CARE DEUTSCHLAND GMBH , FISCHER, Max
发明人： FISCHER, Max
IPC分类号： A61M1/36 , A61M1/34
CPC分类号： A61M1/3649 , A61M1/1601 , A61M1/1603 , A61M1/267 , A61M1/3431 , A61M1/3627 , A61M1/3643 , A61M1/3644 , A61M1/3647 , A61M2202/0413 , A61M2205/33 , A61M2205/3337 , A61M2205/50
摘要： Die Erfindung betrifft ein Verfahren zur Füllung und Spülung eines Blutschlauchsatzes, der ein Pumpsegment für eine Blutpumpe, eine mit einem Eingang eines Dialysators verbundene arterielle Leitung und eine mit einem Ausgang eines Dialysators verbundene venöse Leitung umfasst, über eine Substituatleitung. Es umfasst dabei die Schritte des Verbindens der arteriellen Leitung mit der venösen Leitung sowie Verbinden dieser beiden Leitungen mit einem Rinse-Port, Verbinden der Substituatleitung mit einem Substituat-Port, Öffnen des Rinse-Ports, Füllen der arteriellen und der venösen Leitung, Spülen der arteriellen und der venösen Leitung, Schließen des Rinse-Ports, Zirkulieren des Substituats im Kreislauf aus arterieller Leitung, Dialysator und venöser Leitung durch die Blutpumpe, wobei es dadurch gekennzeichnet ist, dass das Füllen und/oder das Spülen der arteriellen und der venösen Leitung gleichzeitig erfolgt, wobei Substituat aus der Substituatleitung zugeführt wird. Die Erfindung betrifft ausserdem einen Blutschlauchsatz.
摘要翻译：本发明涉及一种用于填充和血液管道组，其包括用于血液泵的泵送段，连接到动脉线路的输入的透析器和装置，连接到透析器的静脉线的输出的潮红，通过代替物管线的方法。它包括动脉线路连接到静脉管路，和连接这两条线与冲洗端口，具有代替物端口连接代替物，打开冲洗端口，填充所述动脉和静脉管线，冲洗步骤动脉和静脉线，关闭冲洗端口，在动脉管线，通过血液泵的透析器和静脉线路的循环中循环的代替物，且其特征在于：所述动脉和静脉线路的同时，填充物和/或漂洗，由此置换从置换提供。本发明还涉及一种血液管道组。

97. 发明申请

WO2004011058A3 BLOOD ASPIRATION SYSTEM AND METHODS OF USE 审中-公开
标题翻译：血液吸入系统及其使用方法
公开(公告)号：WO2004011058A3
公开(公告)日：2005-03-31
申请号：PCT/US0323163
申请日：2003-07-25
申请人： ARTERIA MEDICAL SCIENCE INC
发明人： HOGENDIJK MICHAEL
IPC分类号： A61B17/22 , A61M1/00 , A61M25/00 , A61M5/00 , A61M37/00
CPC分类号： A61M1/3621 , A61B17/22 , A61M1/0066 , A61M1/0068 , A61M25/00 , A61M2025/1052 , A61M2202/0413 , A61M2202/06 , A61M2205/7545
摘要： The present invention is directed to a blood aspiration system that is configured to enable various types of aspiration through a working lumen of a catheter. The blood aspiration system facilitates natural aspiration by providing a circuit between a patient's arterial and venous vasculature, and also comprises a manually actuated pump configured to selectively vary rates of aspiration in the working lumen. The blood aspiration system further comprises an external port that allows suction-assisted aspiration or infusion through the working lumen, and further comprises a detachable filter that removes emboli prior to reperfusing blood into a patient's venous vasculature.
摘要翻译：本发明涉及一种血液抽吸系统，其被配置为能够通过导管的工作腔进行各种类型的抽吸。血液抽吸系统通过在患者的动脉和静脉脉管系统之间提供电路来促进自然抽吸，并且还包括构造成选择性地改变工作腔中的抽吸速率的手动致动泵。血液抽吸系统还包括外部端口，其允许抽吸辅助抽吸或输注通过工作腔，并且还包括可分离的过滤器，其在将血液再次灌注到患者的静脉血管中之前去除栓塞。

98. 发明申请

WO2004009158A2 SYSTEMS AND METHODS FOR PERFORMING PERITONEAL DIALYSIS 审中-公开
标题翻译：用于执行腹膜透析的系统和方法
公开(公告)号：WO2004009158A2
公开(公告)日：2004-01-29
申请号：PCT/US0322267
申请日：2003-07-16
申请人： BAXTER INT , BAXTER HEALTHCARE SA
发明人： CHILDERS ROBERT W , BROWN DAVID S , WARIAR RAMESH , KAROOR SUJATHA , DIN SHAHID , MARTIS LEO , BUCHMANN CODY , SOLTYS PAUL
IPC分类号： A61M1/14 , A61M1/16 , A61M1/28
CPC分类号： A61M1/1696 , A61M1/1656 , A61M1/1658 , A61M1/166 , A61M1/28 , A61M1/284 , A61M1/285 , A61M1/287 , A61M1/288 , A61M2202/0413 , A61M2205/12 , A61M2205/3306 , A61M2205/3327
摘要： In a peritoneal dialysis embodiment of the present invention, spent dialysate from the patient's peritoneal cavity passes, along a patient loop, through a dialyzer having a membrane that separates waste components from the spent dialysate, wherein the patient loop returns fresh dialysate to the patient's peritoneal cavity. The waste components are carried away in a second regeneration loop to a regeneration unit or sorbent cartridge, which absorbs the waste components. The regeneration unit removes undesirable components in the dialysate that were removed from the patient loop by the dialyzer, for example, excess water (ultrafiltrate or UF), toxins and metabolic wastes. Desirable components can be added to the dialysate by the system, such as glucose and electrolytes. The additives assist in maintaining the proper osmotic gradients in the patient to perform dialysis and provide the necessary compounds to the patient.
摘要翻译：在本发明的腹膜透析实施方案中，来自患者腹膜腔的用过的透析液沿着患者环路通过具有膜的透析器，该膜将废组分与用过的透析液分开，其中患者环路将新鲜透析液返回至患者的腹膜腔。废物组分在第二再生回路中被带走到吸收废物组分的再生单元或吸附剂盒。再生单元除去透析器中由透析器移除的透析液中不需要的成分，例如过量的水（超滤液或UF），毒素和代谢废物。理想的组分可以通过该系统添加到透析液中，例如葡萄糖和电解质。添加剂有助于维持患者适当的渗透梯度以进行透析并向患者提供必需的化合物。

99. 发明申请

WO2003063945A1 IRREVERSIBLY CLOSABLE FLOW CONTROL CLAMP 审中-公开
标题翻译：不可逆转的流量控制夹
公开(公告)号：WO2003063945A1
公开(公告)日：2003-08-07
申请号：PCT/US2003/001758
申请日：2003-01-21
申请人： BAXTER INTERNATIONAL INC. , MATHIAS, Jean-Marie , DI STEFANI, Gianni
发明人： MATHIAS, Jean-Marie , DI STEFANI, Gianni
IPC分类号： A61M37/00
CPC分类号： A61M39/284 , A61J1/10 , A61M39/08 , A61M2202/0413 , F16K7/063
摘要： A flow control clamp (30) having first and second legs (36, 38) disposed in a generally facing relationahip. The clamp includes apertures (40, 44) for receiving a flexible tube therethrough. The first and second legs include surfaces disposed to irreversibly secure the legs together in the closed position.
摘要翻译：流量控制夹具（30）具有以大致面对的关系设置的第一和第二腿部（36,38）。夹具包括用于容纳穿过其中的柔性管的孔（40,44）。第一和第二腿包括设置成在闭合位置不可逆地将腿固定在一起的表面。

100. 发明申请

WO2003006098A1 METHODS FOR STERILE ASPIRATION/REINJECTION OF BODILY FLUID 审中-公开
标题翻译：方法吸收/吸收体液
公开(公告)号：WO2003006098A1
公开(公告)日：2003-01-23
申请号：PCT/US2002/021744
申请日：2002-07-10
申请人： MYOCARDIAL THERAPEUTICS, INC.
发明人： EPSTEIN, Stephen , FUCHS, Shmuel , KORNOWSKI, Ran
IPC分类号： A61M31/00
CPC分类号： A61M5/1456 , A61B2090/062 , A61M1/0005 , A61M5/14566 , A61M25/0084 , A61M2025/0089 , A61M2202/0413 , A61M2205/75 , Y10S977/906 , A61M2202/0021
摘要： Methods for aspiration and filtering (95) of a bodily fluid containing undesired components are provided and for treatment of the bodily fluids in a sterile environment (100) in preparation for reinjection of treated aspirate into a donor subject. The invention methods are particularly designed to facilitate transfection of aspirated cells with angiogenesis promoting molecules without danger to the technician or the donor prior to reinjection of the treated cells, either percutaneously or via a surgical opening via catheter or injection needle (72).
摘要翻译：提供了含有不需要的组分的体液的抽吸和过滤（95）的方法，并用于在无菌环境（100）中处理体液，以准备将经处理的抽吸物再注入供体受试者。本发明的方法特别设计用于促进经血管生成促进分子的吸入细胞的转染，而不经由经皮或通过导管或注射针（72）通过外科手术开口重新注射处理的细胞而对技术人员或供体造成危险。

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