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1. 发明申请

WO2018089234A1 TELESCOPING CATHETER 审中-公开
标题翻译：望远镜导管
公开(公告)号：WO2018089234A1
公开(公告)日：2018-05-17
申请号：PCT/US2017/059353
申请日：2017-10-31
申请人： MEDTRONIC VASCULAR INC.
发明人： MAUCH, Kevin
IPC分类号： A61F2/24 , A61F2/95 , A61M25/00 , A61M25/06 , A61M25/01
摘要： A telescoping catheter including an elongated tubular member having a proximal end, a distal end, and a passageway extending between the proximal end and the distal end. The tubular member includes a first tubular segment and a second tubular segment. The first tubular segment and the second tubular segment are slidable relative to one another to vary a length of the tubular member. The first tubular segment includes a first connector mateable with a second connector of the second tubular segment to selectively maintain the first and second tubular segments in an extended position. The second tubular segment includes a second proximal end that is mateable with a handle.
摘要翻译：包括具有近端，远端和在近端和远端之间延伸的通道的细长管状构件的伸缩式导管。该管状构件包括第一管状节段和第二管状节段。第一管状段和第二管状段可相对于彼此滑动以改变管状构件的长度。第一管状节段包括可与第二管状节段的第二连接器匹配的第一连接器，以选择性地将第一和第二管状节段保持在伸出位置。第二管状段包括可与手柄配合的第二近端。

2. 发明申请

WO2017106156A1 DEVICES AND METHODS FOR TRANSCATHETER VALVE LOADING AND IMPLANTATION 审中-公开
标题翻译：装置和方法传输线阀加载和植入
公开(公告)号：WO2017106156A1
公开(公告)日：2017-06-22
申请号：PCT/US2016/066313
申请日：2016-12-13
申请人： MEDTRONIC VASCULAR INC.
发明人： ROTHSTEIN, Paul , BARAJAS-TORRES, Martha , MAUCH, Kevin , SANDSTROM, Jeffrey , MENDELSON, Jill , TRAN, Don
IPC分类号： A61F2/24
CPC分类号： A61F2/2439 , A61F2/2415 , A61F2/2418
摘要： The present disclosure relates to numerous delivery devices (10) and methods for transcatheter prosthetic heart valve (100) loading, deployment and delivery utilizing at least one suture (20, 22, 24). Disclosed delivery devices utilize improved suture routing methods and configurations that reduce suture tangling and also provide the ability to adjust the prosthetic heart valve expansion and contraction prior to the final release of the prosthetic heart valve from the delivery device.
摘要翻译：本公开涉及利用至少一根缝合线（20,22,24）的多种输送装置（10）和用于经导管人工心脏瓣膜（100）装载，展开和输送的方法。公开的输送装置利用改进的缝合线路线方法和构造，其减少缝合线缠结，并且还提供在假体心脏瓣膜从输送装置最终释放之前调节假体心脏瓣膜膨胀和收缩的能力。

3. 发明申请

WO2011102958A1 APPARATUS FOR CREATING A VENOUS VALVE FROM AUTOLOGOUS TISSUE 审中-公开
标题翻译：用于从自动组织创建静脉瓣的装置
公开(公告)号：WO2011102958A1
公开(公告)日：2011-08-25
申请号：PCT/US2011/023168
申请日：2011-01-27
申请人： MEDTRONIC VASCULAR INC. , MAUCH, Kevin , JEFFRIES, Melissa , BIENVENU, Ryan , ARREGUIN, Maria
发明人： MAUCH, Kevin , JEFFRIES, Melissa , BIENVENU, Ryan , ARREGUIN, Maria
IPC分类号： A61F2/24 , A61B17/00
CPC分类号： A61F2/2475 , A61B2017/00783 , A61F2/2427 , A61F2/2442
摘要： An implantable prosthesis (316) for percutaneous placement within a vein (400) that forces opposing portions of the vessel wall of a vein together to create a new valve of autologous vein tissue to be operable to alternate between a valve closed configuration and a valve open configuration. When in a preset closed configuration, the implantable prosthesis pushes or pulls portions of the vessel wall of the vein together to substantially close the vein lumen and prevent retrograde blood flow from backflowing through the new valve in the valve closed configuration. The implantable prosthesis has leg portions (319, 323) that may be pushed apart in response to antegrade blood flow through the vein to allow the new valve to achieve the valve open configuration.
摘要翻译：一种植入式假体（316），用于经皮置于静脉内（400），其将静脉血管壁的相对部分压在一起，以创建自动静脉组织的新阀，以可操作地在阀关闭构型和阀打开之间交替组态。当处于预设的闭合配置中时，可植入假体将静脉血管壁的一部分推入或拉出，以基本上关闭静脉腔，并防止逆流血流在阀关闭构型中回流通过新阀。可植入假体具有腿部（319,323），其可以响应于穿过静脉的顺行血液流动被推开而允许新阀实现阀打开构造。

4. 发明申请

WO2010074853A1 APPARATUS FOR PERCUTANEOUSLY CREATING NATIVE TISSUE VENOUS VALVES 审中-公开
标题翻译：用于创造本质组织静脉瓣的装置
公开(公告)号：WO2010074853A1
公开(公告)日：2010-07-01
申请号：PCT/US2009/065177
申请日：2009-11-19
申请人： MEDTRONIC VASCULAR INC. , MAUCH, Kevin , ARREGUIN, Maria
发明人： MAUCH, Kevin , ARREGUIN, Maria
IPC分类号： A61B17/32 , A61F2/24 , A61M25/10
CPC分类号： A61B17/320016 , A61B2017/22044 , A61B2017/22048 , A61B2017/22061 , A61B2017/22072 , A61F2/2412 , A61F2/2415 , A61F2/2475 , A61M25/1002 , A61M25/1011 , A61M2025/0034 , A61M2025/0037 , A61M2025/1045 , A61M2025/1047 , A61M2025/1081 , A61M2025/1093
摘要： Percutaneous apparatus for forming a bicuspid venous valve from autologous tissue are disclosed. A multilumen catheter is disclosed that includes a delivery shaft positioned on either side of the balloon. When the balloon is inflated within the vein at a treatment location where a bicuspid valve is to be created, the delivery shafts are pressed into the wall of the vein by the inflated balloon so that exit ports in the delivery shafts are at diametrically opposed locations. The delivery shafts may than be used to deliver puncture elements through the exit ports and into the vessel wall to gain access to a subintimal layer of the vein wall. In this manner, the inventive multilumen catheter aids in making properly positioned flaps of venous tissue for creating a bicuspid venous valve from autologous tissue.
摘要翻译：公开了用于从自体组织形成双尖静脉瓣的经皮装置。公开了一种多腔导管，其包括位于气囊两侧的输送轴。当气囊在要产生二尖瓣的治疗位置在静脉内膨胀时，输送轴通过膨胀的气囊被压入静脉的壁中，使得输送轴中的出口处于直径相对的位置。输送轴可以不用于将穿刺元件通过出口端口输送到血管壁中，以进入静脉壁的内膜层。以这种方式，本发明的多腔导管有助于制造适当定位的静脉组织瓣，用于从自体组织产生二尖瓣静脉瓣。

5. 发明申请

WO2009088783A2 OBSTRUCTION REMOVAL SYSTEM 审中-公开
标题翻译：取走系统
公开(公告)号：WO2009088783A2
公开(公告)日：2009-07-16
申请号：PCT/US2008/088234
申请日：2008-12-23
申请人： MEDTRONIC VASCULAR INC. , THOMPSON, Dustin , PERKINS, DH , JOHNSON, Jeremy , SILVER, Michele , MAUCH, Kevin , MACAULAY, Patrick
发明人： THOMPSON, Dustin , PERKINS, DH , JOHNSON, Jeremy , SILVER, Michele , MAUCH, Kevin , MACAULAY, Patrick
IPC分类号： A61B17/22 , A61B17/00 , A61B17/32 , A61B10/02
CPC分类号： A61B17/320758 , A61B10/0266 , A61B17/320708 , A61B17/320725 , A61B2010/0225 , A61B2017/00345 , A61B2017/00398 , A61B2017/00867 , A61B2017/320008 , A61B2017/320012 , A61B2017/32006 , A61B2017/320064 , A61B2017/320741
摘要： An obstruction removal system for percutaneous removal of clots or obstructions within the vascular system is disclosed. The obstruction removal system includes a multi-lumen catheter with a plurality of circulating capture devices attached to or integral with a drive belt. The circulating capture or interference devices affect removal of the clot or obstruction bit-by-bit through a series of passes. The obstruction removal system may include one or more drive mechanisms, such as a pulley system and/or a vacuum source and/or a pressurization source, on its proximal end for driving the drive belt and capture devices through the catheter in a circulating manner. The obstruction removal system may also include one or more cleaning mechanisms, such as a vacuum chamber and/or a fluid rinse chamber, for removing the captured clot pieces from the capture devices.
摘要翻译：公开了一种用于经皮去除血管系统内的血块或障碍物的阻塞去除系统。阻塞去除系统包括多腔导管，其具有附接到驱动带或与传动带一体的多个循环捕获装置。循环捕获或干扰装置通过一系列通路影响凝块的清除或逐位阻塞。障碍物移除系统可以在其近端包括一个或多个驱动机构，例如皮带轮系统和/或真空源和/或加压源，用于驱动驱动带并以循环方式通过导管捕获装置。阻塞去除系统还可以包括一个或多个清洁机构，例如真空室和/或流体冲洗室，用于从捕获装置移除捕获的凝块。

6. 发明申请

WO2018165020A1 DELIVERY SYSTEM HAVING A SHORT CAPSULE SEGMENT AND A CINCH MECHANISM AND METHODS OF USE THEREOF 审中-公开
公开(公告)号：WO2018165020A1
公开(公告)日：2018-09-13
申请号：PCT/US2018/020913
申请日：2018-03-05
申请人： MEDTRONIC VASCULAR, INC.
发明人： DUFFY, Niall , MAUCH, Kevin
IPC分类号： A61F2/24
摘要： A delivery system including a heart valve prosthesis and a delivery catheter. The delivery catheter includes an outer shaft component, an inner shaft component and a cinch mechanism. The outer shaft component has a capsule segment configured to encircle a first portion of the heart valve prosthesis and to thereby hold the first portion of the heart valve prosthesis in a reduced diameter state for delivery to a treatment site. The cinch mechanism surrounds a second portion of the heart valve prosthesis and is configured to hold the remainder of the heart valve prosthesis in a reduced diameter state for delivery to the treatment site. The capsule segment ends proximal of the cinch mechanism when the delivery catheter is in a delivery configuration. The capsule segment and the cinch mechanism in tandem hold the heart valve prosthesis in the reduced diameter state.

7. 发明申请

WO2017106161A3 DEVICES AND METHODS FOR TRANSCATHETER VALVE LOADING AND IMPLANTATION 审中-公开
公开(公告)号：WO2017106161A3
公开(公告)日：2017-06-22
申请号：PCT/US2016/066323
申请日：2016-12-13
申请人： MEDTRONIC VASCULAR INC.
发明人： BARAJAS-TORRES, Martha , MAUCH, Kevin , SANDSTROM, Jeffrey , MENDELSON, Jill , TRAN, Don
IPC分类号： A61F2/24
摘要： The present disclosure relates to numerous devices and methods for transcatheter stented prosthetic heart valve loading and delivery. Such devices and methods reduce suture tangling and also provide the ability to adjust the stented prosthetic heart valve expansion and contraction prior to the final release of the stented prosthetic heart valve (100) from the delivery device (200).

8. 发明申请

WO2017106161A2 DEVICES AND METHODS FOR TRANSCATHETER VALVE LOADING AND IMPLANTATION 审中-公开
标题翻译：装置和方法传输线阀加载和植入
公开(公告)号：WO2017106161A2
公开(公告)日：2017-06-22
申请号：PCT/US2016/066323
申请日：2016-12-13
申请人： MEDTRONIC VASCULAR INC.
发明人： ROTHSTEIN, Paul , BARAJAS-TORRES, Martha , MAUCH, Kevin , SANDSTROM, Jeffrey , MENDELSON, Jill , TRAN, Don
CPC分类号： A61F2/2439 , A61F2/2415 , A61F2/2418
摘要： The present disclosure relates to numerous devices and methods for transcatheter stented prosthetic heart valve loading and delivery. Such devices and methods reduce suture tangling and also provide the ability to adjust the stented prosthetic heart valve expansion and contraction prior to the final release of the stented prosthetic heart valve from the delivery device.
摘要翻译：本公开涉及用于经导管支架假体心脏瓣膜装载和输送的多种装置和方法。这种装置和方法减少了缝合线缠结，并且还提供了在支架假体心脏瓣膜从输送装置最终释放之前调整支架假体心脏瓣膜扩张和收缩的能力。

9. 发明申请

WO2011126676A1 STENT WITH THERAPEUTIC SUBSTANCE 审中-公开
标题翻译：具有治疗药物的STENT
公开(公告)号：WO2011126676A1
公开(公告)日：2011-10-13
申请号：PCT/US2011/028349
申请日：2011-03-14
申请人： MEDTRONIC VASCULAR INC. , THOMPSON, Dustin , ADLER, Paus , ARREGUIN, Maria , MAUCH, Kevin , STORMENT, Christopher , ENSIGN, Lance , ZIMMERMAN, Stephen
发明人： THOMPSON, Dustin , ADLER, Paus , ARREGUIN, Maria , MAUCH, Kevin , STORMENT, Christopher , ENSIGN, Lance , ZIMMERMAN, Stephen
IPC分类号： A61F2/90 , A61F2/00
CPC分类号： A61F2/90 , A61F2250/0067 , A61F2250/0068 , B21F45/008
摘要： A stent (10) includes a wave form that includes a cable (14) including a plurality of strands (316). The wave form has a plurality of struts (18) and a plurality of crowns (20), with each crown connecting two adjacent struts. The wave form is wrapped around a longitudinal axis at a pitch to define a plurality of helical turns. The stent includes a filler located within the cable. The filler includes a therapeutic substance.
摘要翻译：支架（10）包括波形，其包括包括多个股线（316）的电缆（14）。波形具有多个支柱（18）和多个冠部（20），每个冠部连接两个相邻的支柱。波形以间距缠绕在纵向轴线上以限定多个螺旋形匝。支架包括位于电缆内的填充物。填料包括治疗物质。

10. 发明申请

WO2011035222A1 METHOD OF FORMING HOLLOW TUBULAR DRUG ELUTING MEDICAL DEVICES 审中-公开
标题翻译：形成中空管药液治疗医疗器械的方法
公开(公告)号：WO2011035222A1
公开(公告)日：2011-03-24
申请号：PCT/US2010/049439
申请日：2010-09-20
申请人： MEDTRONIC VASCULAR INC. , MAUCH, Kevin , WARD, Sean , JAMOUS, Aram
发明人： MAUCH, Kevin , WARD, Sean , JAMOUS, Aram
IPC分类号： A61L31/16 , A61F2/86
CPC分类号： A61M31/002 , A61F2/88 , A61F2220/0041 , A61F2220/005 , A61F2220/0058 , A61F2220/0075 , A61F2240/001 , A61F2250/0068 , A61L31/16 , Y10T29/49995
摘要： A method of a forming a hollow, drug-eluting medical device includes utilizing a hollow wire having an outer member and a lumen of the outer member, and filling the lumen with a fluid to form a supported hollow wire. The supported hollow wire is shaped into a stent pattern. Openings are formed through the outer member. The supported hollow wire is processed to remove the fluid from the lumen of the outer member without adversely affecting the outer member, leaving the hollow wire shaped into a stent pattern. The lumen is filled with a biologically or pharmacologically active substance.
摘要翻译：形成中空的药物洗脱医疗装置的方法包括利用具有外部构件的外部构件和内腔的中空丝，并且用流体填充内腔以形成支撑的中空丝。支撑的中空丝被成形为支架图案。开口通过外部构件形成。处理支撑的中空丝线以从外部构件的内腔中除去流体，而不会对外部构件产生不利影响，从而将空心线材成形为支架图案。管腔充满生物或药理活性物质。

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