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1. 发明申请

WO2009070240A3 SEPARATION OF NANOSTRUCTURES 审中-公开
标题翻译：纳米结构的分离
公开(公告)号：WO2009070240A3
公开(公告)日：2009-07-16
申请号：PCT/US2008012980
申请日：2008-11-21
申请人： MASSACHUSETTS INST TECHNOLOGY , STRANO MICHAEL S , KIM WOO JAE
发明人： STRANO MICHAEL S , KIM WOO JAE
IPC分类号： B82B3/00 , B82B1/00
CPC分类号： B82B3/00 , B82Y30/00 , B82Y40/00 , C01B32/172 , C01B32/174 , C01B32/18 , C01B2202/02 , C01B2202/06 , C01B2202/26 , C01B2202/36
摘要： The present invention generally relates to the separation of one or more populations of nanostructures from one or more other populations of nanostructures based upon differences in density. An overall mixture of very similar or identical nanostructures may be exposed to a set of conditions under which one population of the nanostructures is affected differently than the other, allowing separating on the basis of differences in density.
摘要翻译：本发明总体上涉及基于密度差异从一个或多个纳米结构群体中分离一个或多个纳米结构群体。非常相似或相同的纳米结构的整体混合物可以暴露于一组纳米结构受到不同影响的一组条件下，从而允许基于密度差异进行分离。

2. 发明申请

WO2009070240A2 SEPARATION OF NANOSTRUCTURES 审中-公开
标题翻译：分离纳米结构
公开(公告)号：WO2009070240A2
公开(公告)日：2009-06-04
申请号：PCT/US2008/012980
申请日：2008-11-21
申请人： MASSACHUSETTS INSTITUTE OF TECHNOLOGY , STRANO, Michael, S. , KIM, Woo, Jae
发明人： STRANO, Michael, S. , KIM, Woo, Jae
IPC分类号： H01L21/00
CPC分类号： B82B3/00 , B82Y30/00 , B82Y40/00 , C01B32/172 , C01B32/174 , C01B32/18 , C01B2202/02 , C01B2202/06 , C01B2202/26 , C01B2202/36
摘要： The present invention generally relates to the separation of one or more populations of nanostructures from one or more other populations of nanostructures based upon differences in density. An overall mixture of very similar or identical nanostructures may be exposed to a set of conditions under which one population of the nanostructures is affected differently than the other, allowing separating on the basis of differences in density.
摘要翻译：本发明一般涉及基于密度差异从纳米结构的一个或多个其它群体分离一个或多个纳米结构群。非常相似或相同的纳米结构的总体混合物可以暴露于一组条件，在这些条件下，一组纳米结构受到不同的影响，允许基于密度差异进行分离。

3. 发明申请

WO2011072228A1 SPECTRAL IMAGING OF PHOTOLUMINESCENT MATERIALS 审中-公开
标题翻译：光致变色材料的光谱成像
公开(公告)号：WO2011072228A1
公开(公告)日：2011-06-16
申请号：PCT/US2010/059897
申请日：2010-12-10
申请人： MASSACHUSETTS INSTITUTE OF TECHNOLOGY , HELLER, Daniel, A. , STRANO, Michael, S.
发明人： HELLER, Daniel, A. , STRANO, Michael, S.
IPC分类号： G01N21/64
CPC分类号： G01N21/6456 , B82Y15/00 , G01N21/6408 , G01N21/6452 , G01N21/6458 , G01N33/22 , G01N2021/6421 , G01N2021/6423
摘要： A system for infrared spectroscopic imaging comprises a light source (10) for illuminating an object to induce luminescent emission in the infrared wavelength range, an optical separator (40), for example a dichroic mirror or a beam splitter in combination with spectral filters, for spatially separating the emission into a first spectral image and a second spectral image, the first spectral image being formed from a shorter wavelength range of light than the second spectral image, and a detector (60) for detecting the first spectral image (70) and the second spectral image (75). The system is used for detecting fluorescence from nanostructures, such as carbon nanotubes, single walled nanotubes SWNT, or quantum dots, wherein a change in fluorescence intensity and/or wavelength is induced by an interaction of an analyte with said nanostructure. The nanostructure may be provided in a biological fluid or within a living or non-living cell.
摘要翻译：用于红外光谱成像的系统包括用于照亮物体以在红外波长范围内引发发光的光源（10），光学分离器（40），例如与分光滤光器组合的分色镜或分束器，用于将所述发射空间分离为第一光谱图像和第二光谱图像，所述第一光谱图像由比所述第二光谱图像的较短的波长范围形成，以及检测器（60），用于检测所述第一光谱图像（70）和第二光谱图像（75）。该系统用于检测来自纳米结构的荧光，例如碳纳米管，单壁纳米管SWNT或量子点，其中通过分析物与所述纳米结构的相互作用诱导荧光强度和/或波长的变化。纳米结构可以设置在生物流体中或生物或非活细胞内。

4. 发明申请

WO2010047772A3 DEPOSITION OF NANOWIRES AND OTHER NANOSCALE OBJECTS ON SURFACES 审中-公开
标题翻译：纳米级和其他纳米材料对表面的沉积
公开(公告)号：WO2010047772A3
公开(公告)日：2010-09-23
申请号：PCT/US2009005695
申请日：2009-10-20
申请人： MASSACHUSETTS INST TECHNOLOGY , STRANO MICHAEL S , SHARMA RICHA
发明人： STRANO MICHAEL S , SHARMA RICHA
IPC分类号： B81B3/00
CPC分类号： B81B3/0089 , B82Y10/00 , H01L51/0003 , H01L51/0012 , H01L51/0049 , Y10T428/24488 , Y10T428/24802 , Y10T428/24917
摘要： The present invention generally relates to the deposition of nanowires and other nanoparticles on surfaces. According to one aspect of the invention, a fluid containing nanoscale objects, such as nanowires, is deposited on a surface having one or more relatively hydrophilic regions and one or more relatively hydrophobic regions. If the fluid is hydrophilic, it will preferentially be located in the relatively hydrophilic regions (or vice versa if the fluid is relatively hydrophobic). The fluid is then allowed to evaporate to cause the nanoscale objects to deposit. For instance, the rate of evaporation may be controlled so as to allow the nanoscale objects to substantially deposit at the centers of the regions and/or at a rate that causes the nanoscale objects to become substantially aligned. In some cases, the regions may be relatively small, e.g., having a minimum surface dimension of less than about 3000 nm. In one set of embodiments, one or more cylindrical droplets may be formed on the surface. For example, the surface may contain a relatively hydrophilic region, having a large surface aspect ratio, surrounded by a relatively hydrophobic region, such that an aqueous fluid deposited on the relatively hydrophilic region forms a cylindrical droplet. Other aspects of the present invention are directed to methods for creating and using such articles, methods for promoting such articles, or the like.
摘要翻译：本发明一般涉及纳米线和其它纳米颗粒在表面上的沉积。根据本发明的一个方面，含有纳米尺度物体（如纳米线）的流体沉积在具有一个或多个相对亲水区域和一个或多个相对疏水区域的表面上。如果流体是亲水性的，它将优先位于相对亲水区域（反之亦然，如果流体相对疏水）。然后允许流体蒸发以使纳米级物体沉积。例如，可以控制蒸发速率，以便允许纳米级物体基本上沉积在区域的中心和/或以导致纳米尺度物体基本对准的速率。在一些情况下，区域可以相对较小，例如具有小于约3000nm的最小表面尺寸。在一组实施例中，可以在表面上形成一个或多个圆柱形液滴。例如，表面可以包含相对亲水的区域，其具有大的表面纵横比，被相对疏水的区域包围，使得沉积在相对亲水区域上的水性流体形成圆柱形液滴。本发明的其它方面涉及用于制造和使用这些物品的方法，用于促进这些制品的方法等。

5. 发明申请

WO2010047772A2 DEPOSITION OF NANOWIRES AND OTHER NANOSCALE OBJECTS ON SURFACES 审中-公开
标题翻译：纳米线和其他纳米级物体在表面的沉积
公开(公告)号：WO2010047772A2
公开(公告)日：2010-04-29
申请号：PCT/US2009/005695
申请日：2009-10-20
申请人： MASSACHUSETTS INSTITUTE OF TECHNOLOGY , STRANO, Michael, S. , SHARMA, Richa
发明人： STRANO, Michael, S. , SHARMA, Richa
IPC分类号： B81C1/00 , B82B3/00
CPC分类号： B81B3/0089 , B82Y10/00 , H01L51/0003 , H01L51/0012 , H01L51/0049 , Y10T428/24488 , Y10T428/24802 , Y10T428/24917
摘要： The present invention generally relates to the deposition of nanowires and other nanoparticles on surfaces. According to one aspect of the invention, a fluid containing nanoscale objects, such as nanowires, is deposited on a surface having one or more relatively hydrophilic regions and one or more relatively hydrophobic regions. If the fluid is hydrophilic, it will preferentially be located in the relatively hydrophilic regions (or vice versa if the fluid is relatively hydrophobic). The fluid is then allowed to evaporate to cause the nanoscale objects to deposit. For instance, the rate of evaporation may be controlled so as to allow the nanoscale objects to substantially deposit at the centers of the regions and/or at a rate that causes the nanoscale objects to become substantially aligned. In some cases, the regions may be relatively small, e.g., having a minimum surface dimension of less than about 3000 nm. In one set of embodiments, one or more cylindrical droplets may be formed on the surface. For example, the surface may contain a relatively hydrophilic region, having a large surface aspect ratio, surrounded by a relatively hydrophobic region, such that an aqueous fluid deposited on the relatively hydrophilic region forms a cylindrical droplet. Other aspects of the present invention are directed to methods for creating and using such articles, methods for promoting such articles, or the like.
摘要翻译：本发明总体上涉及纳米线和其他纳米颗粒在表面上的沉积。根据本发明的一个方面，含纳米尺度物体例如纳米线的流体沉积在具有一个或多个相对亲水区域和一个或多个相对疏水区域的表面上。如果流体是亲水性的，则它将优先位于相对亲水区域中（或者如果流体相对疏水，反之亦然）。然后使流体蒸发以引起纳米级物体沉积。例如，可以控制蒸发速率以便纳米尺度物体基本上在区域的中心沉积和/或以使纳米尺度物体基本对齐的速率沉积。在一些情况下，这些区域可能相对较小，例如具有小于约3000nm的最小表面尺寸。在一组实施例中，可以在表面上形成一个或多个圆柱形液滴。例如，表面可以包含相对亲水的区域，其具有大的表面纵横比，被相对疏水的区域包围，使得沉积在相对亲水的区域上的水性流体形成圆柱形液滴。本发明的其他方面涉及用于创建和使用这种物品的方法，用于促销这种物品的方法等。

6. 发明申请

WO2007013872A3 SENSORS EMPLOYING SINGLE-WALLED CARBON NANOTUBES 审中-公开
公开(公告)号：WO2007013872A3
公开(公告)日：2007-02-01
申请号：PCT/US2005/026074
申请日：2005-07-22
申请人： THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS , STRANO, Michael, S. , BAIK, Seunghyun , BARONE, Paul
发明人： STRANO, Michael, S. , BAIK, Seunghyun , BARONE, Paul
IPC分类号： G01N33/50 , G01N33/52 , G01N33/53 , G01N33/543 , G01N33/548 , G01N33/553 , G01N33/566 , G01N33/573 , G01N33/577 , G01N33/66
摘要： Sensing compositions, sensing element, sensing systems and sensing devices for the detection and/or quantitation of one or more analytes, Compositions comprising carbon nanotubes in which the carbon nanotubes retain their ability to luminesce and in which that luminescence is rendered selectively sensitive to the presence of an analyte. Compositions comprising individually dispersed carbon nanotubes, which are electronically isolated from other carbon nanotubes, yet which are associated with chemical selective species, such as polymers, particularly biological polymers, for example proteins, which can interact selectively with, or more specifically selectivity bind to, an analyte of interest. Chemically selective species bind, preferably non-covalently, to the carbon nanotube and function to provide for analyte selectivity. Chemically selective species include polymers to which one or more chemically selective groups are covalently attached. Chemically selective polymers include, for example, proteins and polysaccharides.

7. 发明申请

WO2003084869A3 METHOD FOR SEPARATING SINGLE-WALL CARBON NANOTUBES AND COMPOSITIONS THEREOF 审中-公开
公开(公告)号：WO2003084869A3
公开(公告)日：2003-10-16
申请号：PCT/US2003/006536
申请日：2003-03-04
申请人： WILLIAM MARSH RICE UNIVERSITY , SMALLEY, Richard E., , HAUGE, Robert H., , KITTRELL, W. Carter, , SIVARAJAN, Ramesh , STRANO, Michael S., , BACHILO, Sergei M., , WEISMAN, R. Bruce,
发明人： SMALLEY, Richard E., , HAUGE, Robert H., , KITTRELL, W. Carter, , SIVARAJAN, Ramesh , STRANO, Michael S., , BACHILO, Sergei M., , WEISMAN, R. Bruce,
IPC分类号： C01B31/02
摘要： The invention relates to a process for sorting and separating a mixture of (n, m) type single-wall carbon nanotubes according to (n, m) type. A mixture of (n, m) type single-wall carbon nanotubes is suspended such that the single-wall carbon nanotubes are individually dispersed. The nanotube suspension can be done in a surfactant-water solution and the surfactant surrounding the nanotubes keeps the nanotube isolated and from aggregating with other nanotubes. The nanotube suspension is acidified to protonate a fraction of the nanotubes. An electric field is applied and the protonated nanotubes migrate in the electric fields at different rates dependent on their (n, m) type. Fractions of nanotubes are collected at different fractionation times. The process of protonation, applying an electric field, and fractionation is repeated at increasingly higher pH to separated the (n, m) nanotube mixture into individual (n, m) nanotube fractions. The separation enables new electronic devices requiring selected (n, m) nanotube types.

8. 发明申请

WO2012030961A2 A NANOTUBE ARRAY FOR OPTICAL DETECTION OF PROTEIN-PROTEIN INTERACTIONS 审中-公开
标题翻译：用于光学检测蛋白质 - 蛋白质相互作用的纳米管阵列
公开(公告)号：WO2012030961A2
公开(公告)日：2012-03-08
申请号：PCT/US2011/049965
申请日：2011-08-31
申请人： MASSACHUSETTS INSTITUTE OF TECHNOLOGY , STRANO, Michael, S. , AHN, Jin-ho , KIM, Jong-Ho , BARONE, Paul, W. , REUEL, Nigel, F.
发明人： STRANO, Michael, S. , AHN, Jin-ho , KIM, Jong-Ho , BARONE, Paul, W. , REUEL, Nigel, F.
IPC分类号： G01N33/543
CPC分类号： G01N33/54373 , B82Y5/00 , B82Y15/00 , G01N33/54353
摘要： A composition can include a nanostructure, and a linker associated with the nanostructure, wherein the linker is configured to interact with a capture protein. The nanostructure can include a single-walled carbon nanotube. A plurality of the compositions can be configured in an array.
摘要翻译：组合物可以包括纳米结构和与纳米结构相关联的接头，其中接头构造成与捕获蛋白相互作用。纳米结构可以包括单壁碳纳米管。多个组合物可以配置成阵列。

9. 发明申请

WO2011022072A3 SYSTEMS AND METHODS FOR HANDLING AND/OR ISOLATING NANOTUBES AND OTHER NANOSTRUCTURES 审中-公开
标题翻译：用于处理和/或分离纳米管和其他纳米结构的系统和方法
公开(公告)号：WO2011022072A3
公开(公告)日：2011-09-09
申请号：PCT/US2010002299
申请日：2010-08-20
申请人： MASSACHUSETTS INST TECHNOLOGY , STRANO MICHAEL S , KIM WOO-JAE , BARONE PAUL W
发明人： STRANO MICHAEL S , KIM WOO-JAE , BARONE PAUL W
IPC分类号： B82B3/00
CPC分类号： B82Y30/00 , B82Y40/00 , C01B32/168 , C01B32/17 , C01B32/174
摘要： Systems and methods related to handling and/or isolating nanotubes and other nanostructures are generally described. In some embodiments, a polymer can be exposed to a collection of agglomerated nanostructures to produce individuated nanostructures. The polymer can comprise one or more pendant groups capable of participating in a pi-pi interaction with at least a portion of the agglomerated nanostructures to produce individuated nanostructures. Individuated nanostructures can be isolated from nanostructures that remain agglomerated. In some cases, individuated nanostructures can be freeze dried to provide, for example, a plurality of nanostructures in solid form. The systems and methods described herein may be so effective in maintaining separation between individuated nanostructures that pluralities of dried nanostructures can be re- suspended in a fluid after they are dried, in some cases with relatively low forces applied during re-suspension.
摘要翻译：通常描述与处理和/或分离纳米管和其他纳米结构有关的系统和方法。在一些实施方案中，聚合物可暴露于聚集的纳米结构集合以产生个体化的纳米结构。聚合物可以包含一个或多个能够与至少一部分团聚纳米结构参与π-π相互作用以产生个体化纳米结构的侧基。个体化的纳米结构可以从纳米结构中分离出来，从而保持凝聚。在一些情况下，可将个体纳米结构冷冻干燥以提供例如多个固体形式的纳米结构。本文所述的系统和方法可以如此有效地维持个别纳米结构之间的分离，使得多个干燥的纳米结构在干燥后可以重新悬浮在流体中，在一些情况下在再悬浮期间施加相对低的力。

10. 发明申请

WO2011081659A1 DEGRADABLE POLYMER NANOSTRUCTURE MATERIALS 审中-公开
标题翻译：可降解聚合物纳米结构材料
公开(公告)号：WO2011081659A1
公开(公告)日：2011-07-07
申请号：PCT/US2010/003189
申请日：2010-12-15
申请人： MASSACHUSETTS INSTITUTE OF TECHNOLOGY , LANGER, Robert, S. , JAKLENEC, Ana , HELLER, Daniel, Alan , ANDERSON, Daniel, Griffith , STRANO, Michael, S.
发明人： LANGER, Robert, S. , JAKLENEC, Ana , HELLER, Daniel, Alan , ANDERSON, Daniel, Griffith , STRANO, Michael, S.
IPC分类号： C08J5/00
CPC分类号： C08J5/005 , B82Y30/00 , C08J2379/00
摘要： This invention relates generally to composites comprising a plurality of nanostructures, and methods of making the same. In some embodiments, the composites further comprise a polymer. In some embodiments, the composites may have desirable properties such as, for example, biodegradability, biocompatibility, and/or high tensile strength. In one embodiment, the plurality of nanostructures comprises carbon nanotubes, and the polymer comprises a poly(beta-amino ester). Various methods are provided for preparing the composites. For example, the polymer and the plurality of nanostructures may, in some embodiments, be combined in a layer-by-layer process to form the composite. High throughput methods for preparing composites having different compositions also are provided for screening composites for desirable properties.
摘要翻译：本发明一般涉及包含多个纳米结构的复合材料及其制备方法。在一些实施方案中，复合材料还包含聚合物。在一些实施方案中，复合材料可具有期望的性质，例如生物降解性，生物相容性和/或高拉伸强度。在一个实施方案中，多个纳米结构包含碳纳米管，并且聚合物包含聚（β-氨基酯）。提供了各种制备复合材料的方法。例如，在一些实施方案中，聚合物和多个纳米结构可以以逐层方法组合以形成复合材料。还提供了用于制备具有不同组成的复合材料的高通量方法用于筛选复合材料以获得所需性能。

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