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1. 发明申请

WO2011092522A3 ANTI-MICROBIAL GLASS COMPOSITION 审中-公开
标题翻译：抗微生物玻璃组合物
公开(公告)号：WO2011092522A3
公开(公告)日：2011-11-24
申请号：PCT/GB2011050163
申请日：2011-02-01
申请人： GILTECH LTD , HEALY DAVID MICHAEL , YOUNG IAIN , GILCHRIST THOMAS
发明人： HEALY DAVID MICHAEL , YOUNG IAIN , GILCHRIST THOMAS
IPC分类号： A01P1/00 , A01N25/08 , A01N59/06 , A01N59/16 , A01N59/20
CPC分类号： A01N59/16 , A01N25/08 , A01N2300/00
摘要： There is described a water-soluble glass composition able to release molybdenum ions in an aqueous environment. In combination with an anti-microbial agent, the glass of the invention provides improved anti¬ microbial activity. Suitable anti-microbial agents include metal ions such as silver, copper, zinc, magnesium, tin or gallium or any combination thereof. Optionally, the metal ions are present as part of the water-soluble glass.
摘要翻译：描述了能够在含水环境中释放钼离子的水溶性玻璃组合物。结合抗微生物剂，本发明的玻璃提供改善的抗微生物活性。合适的抗微生物剂包括金属离子如银，铜，锌，镁，锡或镓或其任何组合。任选地，金属离子作为水溶性玻璃的一部分存在。

2. 发明申请

WO2011092522A2 ANTI-MICROBIAL GLASS COMPOSITION 审中-公开
标题翻译：抗微生物玻璃组合物
公开(公告)号：WO2011092522A2
公开(公告)日：2011-08-04
申请号：PCT/GB2011/050163
申请日：2011-02-01
申请人： GILTECH LIMITED , HEALY, David Michael , YOUNG, Iain , GILCHRIST, Thomas
发明人： HEALY, David Michael , YOUNG, Iain , GILCHRIST, Thomas
CPC分类号： A01N59/16 , A01N25/08 , A01N2300/00
摘要： There is described a water-soluble glass composition able to release molybdenum ions in an aqueous environment. In combination with an anti-microbial agent, the glass of the invention provides improved anti¬ microbial activity. Suitable anti-microbial agents include metal ions such as silver, copper, zinc, magnesium, tin or gallium or any combination thereof. Optionally, the metal ions are present as part of the water-soluble glass.
摘要翻译：描述了一种能够在水性环境中释放钼离子的水溶性玻璃组合物。与抗微生物剂组合，本发明的玻璃提供改善的抗微生物活性。合适的抗微生物剂包括金属离子如银，铜，锌，镁，锡或镓或它们的组合。任选地，金属离子作为水溶性玻璃的一部分存在。

3. 发明申请

WO1996021485A1 HEATING OF PHYSIOLOGICAL FLUIDS 审中-公开
标题翻译：生理流体加热
公开(公告)号：WO1996021485A1
公开(公告)日：1996-07-18
申请号：PCT/GB1996000031
申请日：1996-01-10
申请人： GILTECH LIMITED , GILCHRIST, Thomas , SCOTT, Allan
发明人： GILTECH LIMITED
IPC分类号： A61M05/44
CPC分类号： A61M5/44 , A61M2205/3653
摘要： There is provided an apparatus (1) for warming a physiological fluid, such as blood or a blood product. The apparatus (1) comprises a solid heating body (10) and a heat exchange unit (11) arranged to be engageable with the heating body (10). The apparatus (1) also contains a fluid-tight conduit (19) through which the physiological fluid is carried, the conduit (19) being provided with a pre-formed passageway through the heat exchange unit (11). Heat is passed directly from the heating body (10) (which may be, for example, one or more hot plates (12, 13)) to the heat exchange unit (11) which is desirably disposable. The conduit (19) preferably follows a tortuous path within the apparatus (1), and the temperature of the fluid may be monitored. The apparatus (1) may be portable and may be battery-powered.
摘要翻译：提供了一种用于加热生理液体如血液或血液制品的装置（1）。装置（1）包括固体加热体（10）和布置成可与加热体（10）接合的热交换单元（11）。装置（1）还包含流体密封的管道（19），生理流体通过所述导管（19）被输送，所述管道（19）设置有通过所述热交换单元（11）的预先形成的通道。热量从加热体（10）（其可以是例如一个或多个热板（12,13））直接通到期望为一次性的热交换单元（11）。导管（19）优选地沿着设备（1）内的曲折路径，并且可以监测流体的温度。装置（1）可以是便携式的并且可以是电池供电的。

4. 发明申请

WO0118174A3 CELL GROWTH SUBSTRATE 审中-公开
标题翻译：细胞生长基质
公开(公告)号：WO0118174A3
公开(公告)日：2001-09-27
申请号：PCT/GB0003424
申请日：2000-09-07
申请人： GILTECH LTD , GILCHRIST THOMAS , HEALY DAVID MICHAEL
发明人： GILCHRIST THOMAS , HEALY DAVID MICHAEL
IPC分类号： C12N5/02 , A61L27/38 , C03C3/19 , C03C13/00 , C12N5/00
CPC分类号： C12N5/0068 , A61L27/38 , C03C3/19 , C03C13/00 , C12N2533/12
摘要： A cell culture growth substrate comprising a water soluble glass matrix adapted to sustain growth of living cells. Preferably the substrate comprises or is coated with living cells. The water-soluble glass is advantageously phosphate based and comprises glass fibres or finely comminuted particles. The invention also relates to the use of the growth substrate as an implant to replace or promote repair of damaged tissue in a patient and to a method to encourage growth of living tissue.
摘要翻译：一种细胞培养生长基质，其包含适于维持活细胞生长的水溶性玻璃基质。优选地，底物包含或涂覆有活细胞。水溶性玻璃有利的是磷酸盐基，并且包含玻璃纤维或细粉碎的颗粒。本发明还涉及使用生长衬底作为植入物来替代或促进患者中受损组织的修复以及促进生物体组织生长的方法。

5. 发明申请

WO9733632A3 ALGINATE CONTAINING ANTIMICROBIAL COMPOSITION 审中-公开
标题翻译：含有抗微生物成分的ALGINATE
公开(公告)号：WO9733632A3
公开(公告)日：1997-10-23
申请号：PCT/GB9700715
申请日：1997-03-13
申请人： GILTECH LTD , GILCHRIST EILIDH , GILCHRIST THOMAS
发明人： GILCHRIST EILIDH , GILCHRIST THOMAS
IPC分类号： A61K9/06 , A61K47/12 , A61L15/44 , A61L26/00 , C08K3/40 , C08L5/04
CPC分类号： A61L26/0095 , A61L26/0023 , C08L5/04
摘要： There is provided a composition comprising an admixture of a finely divided alginate (or a salt or derivative thereof) together with a finely divided carrier material. The composition overcomes the problems associated with applying gel-forming alginates to a body surface without formation of a clumpy paste that leads to local irritation. An admixture of sodium alginate and a water-soluble glass carrier material is preferred. Optionally, the alginate and carrier material each have a particle size of less than 150 νm diameter and are present in a weight ratio of 20:80 to 80:20. The presence of the carrier aids even gel formation and also promotes wound healing.

6. 发明申请

WO1996024364A2 ANTIMICROBIAL COMPOSITION COMPOSED OF CONTROLLED RELEASE GLASSES 审中-公开
标题翻译：由控制释放玻璃组成的抗微生物组合物
公开(公告)号：WO1996024364A2
公开(公告)日：1996-08-15
申请号：PCT/GB1996000267
申请日：1996-02-06
申请人： GILTECH LIMITED , HEALY, David, Michael , GILCHRIST, Thomas
发明人： GILTECH LIMITED
IPC分类号： A61K33/38
CPC分类号： C03C3/16 , A61K33/22 , A61K33/245 , A61K33/30 , A61K33/32 , A61K33/34 , A61K33/38 , C03C2204/02 , A61K33/24 , A61K33/06 , A61K33/04 , A61K2300/00
摘要： There is provided an antimicrobial composition for combatting infections. The material is a controlled release glass having two or more agents selected from the group consisting of metals, selenium and boron. Preferably the agents are selected from the group consisting of copper, silver, magnesium, zinc, cerium, manganese bismuth, selenium and boron. The combinations of copper and silver and of copper and zinc are particularly preferred and exhibit synergistic activity. The antimicrobial composition is effective against infections due to Proteus spp.
摘要翻译：提供了用于对抗感染的抗微生物组合物。该材料是具有两种或更多种选自金属，硒和硼的试剂的控释玻璃。优选地，试剂选自铜，银，镁，锌，铈，锰铋，硒和硼。铜和银以及铜和锌的组合是特别优选的并且表现出协同的活性。抗微生物组合物可有效抵抗由于变形杆菌属引起的感染。

7. 发明申请

WO1996017595A1 FOAMABLE FORMULATION AND FOAM 审中-公开
标题翻译：可塑配方和泡沫
公开(公告)号：WO1996017595A1
公开(公告)日：1996-06-13
申请号：PCT/GB1995002830
申请日：1995-12-05
申请人： GILTECH LIMITED , GILCHRIST, Thomas , GILCHRIST, Eilidh
发明人： GILTECH LIMITED
IPC分类号： A61K09/12
CPC分类号： A61K9/122 , A61L15/425 , A61L15/44 , A61L15/46 , A61L15/60 , Y10S514/938 , Y10S514/944 , Y10S514/945
摘要： There is described a foamable formulation comprising a foamable carrier and an active ingredient which may be admixed with the carrier or packaged separately and dispersed into the carrier during the foaming process. Alginate gel is a preferred foamable carrier. The foam produced from such a formulation, and a foam sheet produced by drying the foam, also form part of the invention. The formulation, foam and foam sheet are especially useful for medical applications, for example in treating burns. An apparatus to store the components of the formulation and to generate the foam is also described.
摘要翻译：描述了可发泡制剂，其包含可发泡载体和活性成分，其可以与载体混合或分开包装，并在发泡过程中分散于载体中。藻酸盐凝胶是优选的可发泡载体。由这种配方产生的泡沫和通过干燥泡沫制成的泡沫片也构成了本发明的一部分。制剂，泡沫和泡沫片材对于医疗应用尤其有用，例如在治疗烧伤中。还描述了存储制剂的组分并产生泡沫的装置。

8. 发明申请

WO2003092761A1 SURGICAL MATERIAL COMPRISING WATER GLASS FIBRES 审中-公开
标题翻译：包含水玻璃纤维的外科材料
公开(公告)号：WO2003092761A1
公开(公告)日：2003-11-13
申请号：PCT/GB2003/001918
申请日：2003-05-02
申请人： FITE HOLDINGS LIMITED , GILCHRIST, Thomas , HEALY, David
发明人： GILCHRIST, Thomas , HEALY, David
IPC分类号： A61L27/12
CPC分类号： C03C3/19 , A61L27/12 , A61L27/425 , A61L31/02 , A61L31/123 , Y10T442/2525
摘要： There is provided a surgical material formed using water soluble glass fibres, optionally together with a binding material such as polycaprolactone. One or more layers of non-woven glass fibre material may be present. The material, which is usually in sheet form, can be folded around a defective area of tissue to promote healing, or may be used to prevent adhesion formation following surgery. A method of forming the surgical material is also described.
摘要翻译：提供了使用水溶性玻璃纤维形成的手术材料，任选地与诸如聚己内酯的结合材料一起形成。可以存在一层或多层非织造玻璃纤维材料。通常为片状的材料可以在组织的缺陷区域周围折叠以促进愈合，或者可以用于防止手术后的粘连形成。还描述了形成手术材料的方法。

9. 发明申请

WO1997033632A2 ALGINATE CONTAINING ANTIMICROBIAL COMPOSITION 审中-公开
标题翻译：含有抗微生物成分的ALGINATE
公开(公告)号：WO1997033632A2
公开(公告)日：1997-09-18
申请号：PCT/GB1997000715
申请日：1997-03-13
申请人： GILTECH LIMITED , GILCHRIST, Eilidh , GILCHRIST, Thomas
发明人： GILTECH LIMITED
IPC分类号： A61L15/44
CPC分类号： A61L26/0095 , A61L26/0023 , C08L5/04
摘要： There is provided a composition comprising an admixture of a finely divided alginate (or a salt or derivative thereof) together with a finely divided carrier material. The composition overcomes the problems associated with applying gel-forming alginates to a body surface without formation of a clumpy paste that leads to local irritation. An admixture of sodium alginate and a water-soluble glass carrier material is preferred. Optionally, the alginate and carrier material each have a particle size of less than 150 mu m diameter and are present in a weight ratio of 20:80 to 80:20. The presence of the carrier aids even gel formation and also promotes wound healing.
摘要翻译：提供了一种组合物，其包含细分散的藻酸盐（或其盐或衍生物）与细分散的载体材料的混合物。该组合物克服了将凝胶形成藻酸盐施用于身体表面而不形成导致局部刺激的团块状糊剂的问题。优选藻酸钠和水溶性玻璃载体材料的混合物。任选地，藻酸盐和载体材料各自具有小于150μm直径的粒度，并且以20:80至80:20的重量比存在。载体的存在有助于甚至形成凝胶并且还促进伤口愈合。

10. 发明申请

WO1996021410A1 SELF-ADHESIVE LAMINATE 审中-公开
标题翻译：自粘层压板
公开(公告)号：WO1996021410A1
公开(公告)日：1996-07-18
申请号：PCT/GB1996000055
申请日：1996-01-12
申请人： GILTECH LIMITED , GILCHRIST, Thomas , HEALY, David, Michael
发明人： GILTECH LIMITED
IPC分类号： A61F13/02
CPC分类号： A61F13/023 , A61F2013/00153 , A61F2013/00523 , A61F2013/00731 , A61F2013/00748 , A61F2013/00804 , A61F2013/00817 , A61F2013/00829 , A61F2013/00846 , A61F2013/00863 , A61F2013/00868 , A61F2013/00906 , A61F2013/0091 , A61F2013/00927
摘要： There is provided a laminate suitable for use as a wound dressing or as a transdermal medicament delivery system. The laminate is comprised of a carrier sheet sandwiched between a removable cover sheet and a removable backing sheet. The laminate has a cover sheet tab and a backing sheet tab, both tabs extending away from the carrier sheet. The laminate also comprises a holding portion. The holding portion and the two tabs facilitate application of the carrier sheet, which is normally in polyurethane film, to a surface of the patient and avoids stretching or wrinkling the carrier sheet. The carrier sheet will normally comprise a therapeutic agent, such as a bacteriostat and may be provided with an adhesive island to cover the wound.
摘要翻译：提供了适合用作伤口敷料或透皮药物递送系统的层压材料。层压体由夹在可移除的覆盖片和可移除的背衬片之间的载体片构成。层压板具有盖板凸片和背板薄片，两个凸片远离载体片延伸。层压板还包括保持部分。保持部分和两个舌片有助于将通常在聚氨酯膜中的载体片材施加到患者的表面，并避免载体片材的拉伸或起皱。载体片通常包含治疗剂，例如抑菌剂，并且可以设置有用于覆盖伤口的粘合岛。

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