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1. 发明申请

US20040135080A1 Rectilinear ion trap and mass analyzer system and method 有权
标题翻译：直线离子阱和质量分析仪系统及方法
公开(公告)号：US20040135080A1
公开(公告)日：2004-07-15
申请号：US10656667
申请日：2003-09-04
发明人： Zheng Ouyang , Rober t G. Cooks
IPC分类号： H01J049/42
CPC分类号： H01J49/422
摘要： A new geometry ion trap and its use as a mass spectrometer is described. The ion traps can be combined linearly and in parallel to form systems for mass storage, analysis, fragmentation, separation, etc. of ions. The ion trap has a simple rectilinear geometry with a high trapping capacity. It can be operated to provide mass analysis in the mass-selective instability mode as well as the mass-selective stability mode. Arrays of multiple ion traps allow combinations of multiple gas-phase processes to be applied to the trapped ions to achieve high sensitivity, high selectivity and/or higher throughput in the analysis of ions.
摘要翻译：描述了一种新的几何离子阱及其作为质谱仪的用途。离子阱可以线性并联并联以形成离子的大容量存储，分析，分离，分离等的系统。离子阱具有简单的直线几何形状，具有高捕集能力。可以在质量选择不稳定模式以及质量选择稳定模式下进行质量分析。多个离子阱的阵列允许将多个气相过程的组合施加到捕获的离子上，以在离子分析中实现高灵敏度，高选择性和/或更高的通量。

2. 发明申请

US20030219572A1 Direct write lithography system 失效
标题翻译：直写光刻系统
公开(公告)号：US20030219572A1
公开(公告)日：2003-11-27
申请号：US10391956
申请日：2003-03-19
发明人： Pieter Kruit
IPC分类号： B32B003/10 , G03F007/20 , G21K001/08 , H01J003/14 , H01J003/26 , H01J049/42 , G21G005/00
CPC分类号： B82Y10/00 , B82Y40/00 , G03F7/70375 , H01J37/3174 , H01J37/3177 , H01J2237/31774 , H01J2237/31777 , H01J2237/31779 , Y10S438/942 , Y10S438/949 , Y10T428/24802
摘要： The invention pertains to a direct write lithography system comprising: A converter comprising an array of light controllable electron sources, each field emitter being arranged for converting light into an electron beam, the field emitters having an element distance between each two adjacent field emitters, each field emitter having an activation area; A plurality of individually controllable light sources, each light source arranged for activating one field emitter; Controller means for controlling each light source individually; Focussing means for focussing each electron beam from the field emitters With a diameter smaller than the diameter of a light source on an object plane.
摘要翻译：本发明涉及一种直写式光刻系统，包括：A转换器，包括一组光可控电子源，每个场发射器布置成将光转换成电子束，场发射器在每两个相邻的场发射器之间具有元件距离，每个场发射器具有激活区域; 多个可单独控制的光源，每个光源被布置用于激活一个场发射器; 用于单独控制每个光源的控制器装置; 用于聚焦来自场发射器的每个电子束的聚焦装置，其直径小于物平面上光源的直径。

3. 发明申请

US20030189168A1 Fragmentation of ions by resonant excitation in a low pressure ion trap 审中-公开
标题翻译：在低压离子阱中通过共振激发分离离子
公开(公告)号：US20030189168A1
公开(公告)日：2003-10-09
申请号：US10310000
申请日：2002-12-04
发明人： Frank Londry , Bruce A. Collings , William R. Stott
IPC分类号： H01J049/42
CPC分类号： H01J49/4225 , H01J49/0063 , H01J49/421
摘要： In the field of mass spectrometry, a method and apparatus for fragmenting ions with a relatively high degree of resolution. The technique includes trapping the ions in an ion trap, preferably a linear ion trap, in which the background or neutral gas pressure is preferably on the order of 10null5 Torr. The trapped ions are resonantly excited for a relatively extended period of time, e.g., exceeding 50 ms, at relatively low excitation levels, e.g., less than 1V(0nullpk). The technique allows selective dissociation of ions with a discrimination of at least about 1 m/z at a practical fragmentation efficiencies. Apparatus and related methods are also disclosed for obtaining MS, MS2, MS3 and MSn spectrums at relatively high resolutions using the low pressure fragmentation technique.
摘要翻译：在质谱领域中，以分辨率较高的方式分离离子的方法和装置。该技术包括将离子俘获在离子阱中，优选线性离子阱，其中背景或中性气体压力优选在10 -5 Torr量级。被俘获的离子在相对较低的激发水平（例如小于1V（0-pk））下相对延长的时间段（例如超过50ms）被共振激发。该技术允许在实际的分裂效率下以至少约1m / z的区别选择性离解离子。还公开了使用低压碎裂技术以相对高分辨率获得MS，MS 2，MS 3和MS n谱的装置和相关方法。

4. 发明申请

US20030071210A1 Ion trap device 有权
标题翻译：离子阱装置
公开(公告)号：US20030071210A1
公开(公告)日：2003-04-17
申请号：US10244534
申请日：2002-09-17
申请人： SHIMADZU CORPORATION
发明人： Eizo Kawato
IPC分类号： H01J049/42
CPC分类号： H01J49/4205 , H01J49/022
摘要： In an ion trap device using an RF electric field to trap ions, when the amplitude of the RF voltage for generating the RF electric field is changed from a first value to a second value, it is changed according to the exponential function of time. And the time constant of the exponential function is set equal to or longer than the time constant of the resonant circuit for generating the RF voltage. Owing to this, the time necessary to change the RF voltage is shortened, and an overshoot, undershoot, or ringing of an actual RF voltage on the electrode or electrodes of an ion trap is avoided when the RF voltage setting value is changed, so that the movement of ions in the ion trap is not disturbed and the throughput of the ion trap device is improved.
摘要翻译：在使用RF电场捕获离子的离子阱装置中，当用于产生RF电场的RF电压的幅度从第一值变为第二值时，根据时间的指数函数来改变。并且将指数函数的时间常数设定为等于或大于用于产生RF电压的谐振电路的时间常数。因此，改变RF电压所需的时间被缩短，并且当RF电压设定值改变时，避免了离子阱的电极或电极上的实际RF电压的过冲，下冲或振铃，使得离子阱中的离子的运动不受干扰，并且提高了离子阱装置的生产量。

5. 发明申请

US20030042415A1 Method of reducing space charge in a linear ion trap mass spectrometer 有权
公开(公告)号：US20030042415A1
公开(公告)日：2003-03-06
申请号：US10232588
申请日：2002-08-30
申请人： MDS Inc., doing business as MDS Sciex
发明人： James W. Hager
IPC分类号： H01J049/42
CPC分类号： H01J49/4265 , H01J49/4225 , Y10S430/143
摘要： A method of setting a fill time for a mass spectrometer including a linear ion is provided. The mass spectrometer is operated first in a transmission mode and ions are supplied to the mass spectrometer. Ions are detected as they pass through at least part of the mass spectrometer in a preset time period, to determine the ion current. From a desired maximum charge density for the ion trap and the ion current, a fill time for the ion trap is determined. The mass spectrometer is operated in a trapping mode to trap ions in the ion trap, and the ion trap is filled for the fill time, as just determined. This utilizes the ion trap to its maximum, while avoiding problems due to overfilling the trap, causing space charge effects.

6. 发明申请

US20020195559A1 Ion trap mass spectrometer 有权
标题翻译：离子阱质谱仪
公开(公告)号：US20020195559A1
公开(公告)日：2002-12-26
申请号：US10170687
申请日：2002-06-14
申请人： Shimadzu Corporation
发明人： Kozo Miseki
IPC分类号： H01J049/42
CPC分类号： H01J49/424 , H01J49/428
摘要： In an ion trap mass spectrometer including an ion trap space surrounded by a ring electrode and two end cap electrodes placed opposite each other with the ring electrode between them, a method of trapping object ions of a predetermined mass-to-charge ratio in the ion trap space more assuredly and effectively. The method includes the steps of: applying an RF voltage to the ring electrode to trap the object ions; and applying an auxiliary AC voltage to the end cap electrodes, where the auxiliary voltage has a frequency spectrum with a first notch at the basic frequency of the object ions and a second notch at a a beat frequency. Then the second stage is performed where another auxiliary AC voltage of the beat frequency is applied to the end cap electrodes to expel non-object ions still remaining in the ion trap space.
摘要翻译：在离子阱质谱仪中，包括由环形电极和两个端盖电极围绕的离子阱空间，两个端盖电极与它们之间的环形电极相对放置，在离子中捕获预定质荷比的物体离子的方法陷阱空间更加放心和有效。该方法包括以下步骤：向环形电极施加RF电压以捕获物体离子; 以及向所述端盖电极施加辅助AC电压，其中所述辅助电压具有在所述物体离子的基本频率处具有第一陷波的频谱和以拍频的第二陷波。然后执行第二阶段，其中将拍频的另一辅助AC电压施加到端帽电极以排出仍然留在离子阱空间中的非对象离子。

7. 发明申请

US20020109099A1 Apparatus for magnetically scanning and/or switching a charged-particle beam 有权
标题翻译：用于磁扫描和/或切换带电粒子束的装置
公开(公告)号：US20020109099A1
公开(公告)日：2002-08-15
申请号：US09949072
申请日：2001-09-07
申请人： Diamond Semiconductor Group, LLC
发明人： Nicholas White , Edward Bell , Philip Harvey
IPC分类号： G21K001/08 , H01J003/14 , H01J003/26 , H01J049/42
CPC分类号： H01J37/1475 , H01J37/147 , H01J2237/31701
摘要： An apparatus is provided for one-dimensional magnetic scanning or switching of a charged particle beam. The apparatus can be extended to two dimensions at the cost of added complexity.
摘要翻译：提供了用于一维磁扫描或带电粒子束切换的装置。该装置可以以增加的复杂性为代价扩展到两个维度。

8. 发明申请

US20010040220A1 Methods and apparatus for operating high energy accelerator in low energy mode 有权
标题翻译：在低能量模式下运行高能量加速器的方法和装置
公开(公告)号：US20010040220A1
公开(公告)日：2001-11-15
申请号：US09779243
申请日：2001-02-08
申请人： Varian Semiconductor Equipment Associates, Inc.
发明人： Bjorn O. Pedersen , Peter E. Maciejowski , William G. Goodenough , Paul J. Murphy , Charles M. McKenna
IPC分类号： G21K001/08 , H01J003/14 , H01J003/26 , H01J049/42
CPC分类号： H01J37/3171 , H01J2237/04735 , H05H5/06
摘要： Methods and apparatus are provided for efficiently operating an ion implanter which includes a charged particle accelerator in a high energy mode and in a low energy mode. The charged particle accelerator includes a high voltage power supply, an accelerator column coupled to the high voltage power supply and a switching assembly. The accelerator column includes a plurality of accelerator electrodes. The high voltage power supply is disabled from energizing the accelerator column in the low energy mode. The switching assembly includes switching elements for electrically connecting the accelerator electrodes to a reference potential in the low energy mode and for electrically isolating the accelerator electrodes from the reference potential in the high energy mode. The switching assembly prevents positive potentials on the accelerator electrodes and thus minimizes space charge expansion of the beam when transporting positive ion beams in the low energy mode.
摘要翻译：提供了用于有效地操作离子注入机的方法和装置，其包括高能量模式和低能量模式的带电粒子加速器。带电粒子加速器包括高压电源，耦合到高压电源的加速器柱和开关组件。加速器柱包括多个加速器电极。在低能量模式下，高压电源禁止加速器柱通电。开关组件包括用于将加速器电极电连接到低能量模式中的参考电位并且用于将加速器电极与高能量模式中的参考电位电隔离的开关元件。开关组件防止加速器电极上的正电位，从而当以低能量模式传输正离子束时，使光束的空间电荷膨胀最小化。

9. 发明申请

US20010000618A1 Mass spectrometer 有权
标题翻译：质谱仪
公开(公告)号：US20010000618A1
公开(公告)日：2001-05-03
申请号：US09739217
申请日：2000-12-19
申请人： Hitachi, Ltd.
发明人： Yasuaki Takada , Minoru Sakairi , Takayuki Nabeshima , Yukiko Hirabayashi , Hideaki Koizumi
IPC分类号： H01J049/42
CPC分类号： H01J49/067 , H01J49/04
摘要： A mass spectrometer comprising an ionization means For ionizing sample compounds to be analyzed mass spectro-scopically in an atmospheric pressure, a sample solution supply means for supplying a solution containing the sample compounds to the ionization means, means for feeding the ions formed by the ionization means through an aperture disposed in an electrode into a vacuum region and a ion trap type mass spectroscopic means for mass spectroscopically analyzing ions entered through the aperture into the vacuum region, in which an ion decelerating electric field forming means is disposed between the electrode disposed with the aperture and an electrode disposed with an ion entrance opening for entering the ions into the ion trap type mass spectroscopic means for forming an electric field for decelerating the ions, and the ions injected to the ion trap mass spectroscopic means is lowered. This facilitates accumulation ions in the ion crap mass spectralyzing means even if a high drift voltage is used thereby enabling high sensitivity analysis for polar compounds such as peptides.
摘要翻译：一种包含电离装置的质谱仪用于在大气压下电离质谱分析的样品化合物，向离子化装置供给含有样品化合物的溶液的样品溶液供给装置，用于将由离子化形成的离子进料的装置意味着通过设置在电极中的孔进入真空区域和离子阱型质谱分析装置，用于质谱分析通过孔进入真空区域的离子，其中离子减速电场形成装置设置在设置有所述孔和电极设置有离子入口，用于将离子进入离子阱型质谱分析装置，用于形成用于使离子减速的电场，以及注入离子阱质谱分析装置的离子。即使使用高漂移电压，也有利于离子废物质谱分析手段中的积聚离子，从而能够对极性化合物如肽进行高灵敏度分析。

10. 发明申请

US20040245460A1 Integrated shield in multipole rod assemblies for mass spectrometers 有权
标题翻译：用于质谱仪的多极杆组件中集成屏蔽
公开(公告)号：US20040245460A1
公开(公告)日：2004-12-09
申请号：US10456894
申请日：2003-06-05
发明人： Berg A. Tehlirian , Michael W. Senko , Nigel P. Gore
IPC分类号： H01J049/42
CPC分类号： H01J49/4225 , H01J49/063
摘要： Multipole rod assemblies for guiding or trapping ions in a mass spectrometer. A multipole rod assembly includes a plurality of modules. Each module includes a shield element, one or more insulating elements coupled to the shield element, and one or more multipole rods mounted on the insulating elements, wherein the modules are coupled together to form the multipole rod assembly such that the multipole rods of the modules define an interior volume for guiding or trapping ions.
摘要翻译：用于在质谱仪中引导或捕获离子的多极杆组件。多极杆组件包括多个模块。每个模块包括屏蔽元件，耦合到屏蔽元件的一个或多个绝缘元件和安装在绝缘元件上的一个或多个多极棒，其中模块耦合在一起以形成多极杆组件，使得模块的多极杆限定用于引导或捕获离子的内部容积。

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