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    • 5. 发明授权
    • Process for the preparation of hydrazones
    • 制备腙的方法
    • US3943132A
    • 1976-03-09
    • US406467
    • 1973-10-15
    • Jean-Pierre SchirmannHenri MathaisPierre TellierFrancis Weiss
    • Jean-Pierre SchirmannHenri MathaisPierre TellierFrancis Weiss
    • C07D213/77C07B43/00C07C20060101C07C67/00C07C241/00C07C251/76C07C251/82C07C251/84C07C251/86C07D20060101C07C109/14C07C109/16C07C109/18
    • C07C249/16C07C251/76C07C251/84
    • This invention relates to a method of preparing hydrazones of the formula ##EQU1## in which R.sub.1 and R.sub.2, which may be identical or different, represent a linear alkyl radical of from 1 to 12 carbon atoms, a branched alkyl or cycloalkyl radical of from 3 to 12 carbon atoms, an aromatic radical of from 6 to 12 carbon atoms having a benzene or naphthalene nucleus, or a radical of from 5 to 12 carbon atoms having a pyridine nucleus, or R.sub.1 and R.sub.2 together form a linear or branched alkylene radical of from 3 to 12 carbon atoms in which one of the carbon atoms of the chain may be replaced by an oxygen atom, all of the above radicals being unsubstituted or substituted by one or more atoms or groups such as chlorine, bromine, fluorine, or iodine atoms or hydroxy, ether, carboxylic acid, carboxylic amide or ester, nitrile, nitro, or sulphonic acid or amide groups, or one of the two radicals R.sub.1 and R.sub.2 may be a hydrogen atom, and in which R.sub.3 and R.sub.4, which may be identical or different, represent a hydrogen atom, a linear alkyl or cycloalkyl radical of from 3 to 12 carbon atoms, in which one of the carbon atoms of the cycloalkyl radical may be replaced by an oxygen atom, or an aromatic hydrocarbon radical of from 6 to 12 carbon atoms or R.sub.3 and R.sub.4 together represent a linear or branched alkylene radical of from 3 to 11 carbon atoms, the above radicals being unsubstituted or substituted by atoms or groups such as chlorine, bromine, fluorine, ethylenic groups, nitro, hydroxy, alkoxy, or carboxylic acid or ester radicals , which comprises reacting a primary or secondary amine of the formulaWherein R.sub.1 and R.sub.2 are as defined above, ammonia, and a carbonyl compound of the formulaWherein R.sub.3 and R.sub.4 are as defined above, with a peroxide compound.
    • 本发明涉及制备式R 1 R 3 ANGLE NN = C ANGLE(I)R 2 R 4的腙的方法,其中可以相同或不同的R 1和R 2表示1至12个碳原子的直链烷基,支链 具有3至12个碳原子的烷基或环烷基,具有苯或萘核的6至12个碳原子的芳族基团或具有吡啶核的5至12个碳原子的基团,或者R 1和R 2一起形成 具有3至12个碳原子的直链或支链亚烷基,其中链中的一个碳原子可以被氧原子代替,所有上述基团都是未取代的或被一个或多个原子或基团取代,例如氯 ,溴,氟或碘原子或羟基,醚,羧酸,羧酰胺或酯,腈,硝基或磺酸或酰胺基,或两个基团R 1和R 2之一可以是氢原子,其中 R3和R4可以相同或相同 不同的是氢原子,具有3-12个碳原子的直链烷基或环烷基,其中环烷基的一个碳原子可以被氧原子取代,或6-12的芳族烃基 碳原子或R3和R4一起表示具有3至11个碳原子的直链或支链亚烷基,上述基团是未取代的或被诸如氯,溴,氟,烯基,硝基,羟基,烷氧基, 或羧酸或酯基,其包括使式WHEREIN R 1和R 2如上所定义的伯胺或仲胺与氨过氧化合物与式WHEREIN R 3和R 4如上定义的羰基化合物反应。