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1. 发明申请

US20130320205A1 HIGH FIELD ASYMMETRIC ION MOBILITY SPECTROMETRY (FAIMS) METHODS AND DEVICES WITH VOLTAGE-GAS COMPOSITION LINKED SCANS 有权
标题翻译：具有电压气体组成的高场非对称离子光谱（FAIMS）方法和装置连接扫描
公开(公告)号：US20130320205A1
公开(公告)日：2013-12-05
申请号：US13485346
申请日：2012-05-31
申请人： Gary Glish , Mark Ridgeway , Alice Pilo
发明人： Gary Glish , Mark Ridgeway , Alice Pilo
IPC分类号： H01J49/40 , B01D59/46
CPC分类号： G01N27/624
摘要： Improved methods and devices for analysis of gas phase ions via ion mobility type analyzers, particularly high field asymmetric waveform ion mobility analyzers (FAIMS), by linking gas composition and/or flow rate with the scanning of compensation voltage or asymmetric waveform amplitude are provided. Linking these parameters results in improvements in resolution, sensitivity, and selectivity. The methods and devices according to the presently disclosed subject matter provide for the improvement in resolution for specific ions without affecting the entire FAIMS spectrum.
摘要翻译：提供了通过将气体组成和/或流速与补偿电压扫描或非对称波形幅度相连接的离子迁移率型分析仪，特别是高场不对称波形离子迁移率分析仪（FAIMS）来分析气相离子的改进方法和装置。链接这些参数可以提高分辨率，灵敏度和选择性。根据目前公开的主题的方法和装置提供特定离子的分辨率的改进而不影响整个FAIMS光谱。

2. 发明申请

US20110139973A1 TOF MASS SPECTROMETER FOR STIGMATIC IMAGING AND ASSOCIATED METHOD 有权
标题翻译：用于静态成像和相关方法的TOF质谱仪
公开(公告)号：US20110139973A1
公开(公告)日：2011-06-16
申请号：US13054295
申请日：2009-07-16
申请人： Andrew Bowdler
发明人： Andrew Bowdler
IPC分类号： H01J49/40 , B01D59/46 , G01D18/00
CPC分类号： H01J49/40 , H01J49/0004 , H01J49/067
摘要： The present invention is concerned with improving the focusing of ions having a particular mass to charge ratio by optimising the electric field for the focusing of ions having that particular mass to charge ratio. In particular, the stigmatic focusing of ions can be improved by adjusting a voltage applied to an ion-optical lens 50 for ions of different mass to charge ratios as those ions pass through the lens. In one embodiment, a digital to analogue converter 32 and amplifier 34 are AC coupled to a high voltage DC power supply unit 38 by high voltage capacitor 36. The digital to analogue converter 32 generates a low voltage wave form which is amplified by the amplifier 34 and then added to the output of the high voltage supply 38 so that the desired voltage waveform is generated and applied to ion-optical lens 50 as ions pass through the lens.
摘要翻译：本发明涉及通过优化具有该特定质荷比的离子的聚焦的电场来改进具有特定质荷比的离子的聚焦。特别地，通过调节离子光学透镜50对于离子通过透镜而具有不同质荷比的离子的电压，可以提高离子的眩光聚焦。在一个实施例中，数模转换器32和放大器34通过高电压电容器36与高电压DC电源单元38交流耦合。数模转换器32产生由放大器34放大的低电压波形然后添加到高压电源38的输出端，使得产生期望的电压波形并且当离子通过透镜时将其施加到离子光学透镜50。

3. 发明授权

US09458543B2 Active matrix electrowetting-on-dielectric device 有权
标题翻译：有源矩阵电润湿介电器件
公开(公告)号：US09458543B2
公开(公告)日：2016-10-04
申请号：US13693250
申请日：2012-12-04
申请人： SHARP KABUSHIKI KAISHA
发明人： Benjamin James Hadwen
IPC分类号： G01R27/28 , B01D59/46 , G06F3/038 , C25B9/04 , B01L3/00 , G02B26/00
CPC分类号： C25B9/04 , B01L3/502792 , B01L2300/0816 , B01L2300/0887 , B01L2400/0427 , G02B26/005 , G09G3/348
摘要： An active matrix electrowetting on dielectric (AM-EWOD) device includes a plurality of array elements configured to manipulate one or more droplets of fluid on an array, each of the array elements including a corresponding array element circuit. Each array element circuit includes write circuitry configured to write data to the corresponding array element for controlling the manipulation of the droplets of fluid, and sensor circuitry configured to sense an impedance present at the corresponding array element. The sensor circuitry is configured to operate in one of a normal mode of sensitivity for detection of a droplet, or a high mode of sensitivity to detect an electric property of an array element hydrophobic surface. The sensor circuitry includes an active element, such as an active capacitor or active transistor, and a capacitance across the active element is different in the normal sensitivity mode as compared to the high sensitivity mode.
摘要翻译：在电介质（AM-EWOD）器件上的有源矩阵电润湿包括多个阵列元件，其被配置为操纵阵列上的一个或多个液滴，每个阵列元件包括相应的阵列元件电路。每个阵列元件电路包括写入电路，其被配置为将数据写入对应的阵列元件，以控制流体液滴的操纵;以及传感器电路，其被配置为感测存在于相应的阵列元件上的阻抗。传感器电路被配置为以用于检测液滴的正常灵敏模式或高灵敏度模式中的一种操作，以检测阵列元件疏水表面的电性质。传感器电路包括有源元件，例如有源电容器或有源晶体管，并且与高灵敏度模式相比，有源元件上的电容在正常灵敏度模式中是不同的。

4. 发明申请

US20120305762A1 ION ISOLATION METHOD AND MASS SPECTROMETER 审中-公开
标题翻译：离子分离方法和质谱仪
公开(公告)号：US20120305762A1
公开(公告)日：2012-12-06
申请号：US13579334
申请日：2010-12-13
申请人： Akihito Kaneko , Atsumu Hirabayashi
发明人： Akihito Kaneko , Atsumu Hirabayashi
IPC分类号： H01J49/42 , B01D59/46
CPC分类号： H01J49/427
摘要： Disclosed is a method whereby predetermined ions are isolated and ions to be left in an ion trap are left at the time of performing mass spectrometry using the ion trap. In order to have high ion isolation accuracy and to shorten a time necessary for ion isolation, a first time wherein ions having a lower mass than the ions to be left are isolated is set shorter than a second time wherein ions having a higher mass than the ions to be left are isolated.
摘要翻译：公开了一种使用离子阱进行质谱分析的方法，其中分离预定离子并留下离子阱中的离子。为了具有高的离子隔离精度并缩短离子分离所需的时间，其中离子离子质量比离开离子质量低的离子的第一次被设定为比第二次时间短，其中离子质量比要离开的离子是孤立的。

5. 发明申请

US20110031389A1 System and Method for Trapping and Measuring a Charged Particle in a Liquid 有权
标题翻译：用于捕集和测量液体中带电粒子的系统和方法
公开(公告)号：US20110031389A1
公开(公告)日：2011-02-10
申请号：US12730226
申请日：2010-03-23
申请人： Mark A. Reed , Predrag S. Krstic , Weihua Guan , Xiongce Zhao
发明人： Mark A. Reed , Predrag S. Krstic , Weihua Guan , Xiongce Zhao
IPC分类号： B01D59/46
CPC分类号： G01N33/48721
摘要： A system and method for trapping a charged particle is disclosed. A time-varying periodic multipole electric potential is generated in a trapping volume. A charged particle under the influence of the multipole electric field is confined to the trapping volume. A three electrode configuration giving rise to a 3D Paul trap and a four planar electrode configuration giving rise to a 2D Paul trap are disclosed.
摘要翻译：公开了一种用于捕获带电粒子的系统和方法。在捕集体积中产生时变周期性多极电位。在多极电场影响下的带电粒子被限制在捕获体积上。公开了产生3D保护陷阱的三电极配置和引起2D保护陷阱的四个平面电极配置。

6. 发明授权

US2606291A Method and apparatus for material separation 失效
标题翻译：材料分离方法和装置
公开(公告)号：US2606291A
公开(公告)日：1952-08-05
申请号：US65351846
申请日：1946-03-11
申请人： WILSON ROBERT R
发明人： WILSON ROBERT R
IPC分类号： B01D59/46 , H01J49/34
CPC分类号： H01J49/34 , B01D59/46

7. 发明授权

US09070543B2 Ion mobility separator with variable effective length 有权
标题翻译：具有可变有效长度的离子迁移分离器
公开(公告)号：US09070543B2
公开(公告)日：2015-06-30
申请号：US14479805
申请日：2014-09-08
申请人： Micromass UK Limited
发明人： Martin Raymond Green , David J. Langridge , Jason Lee Wildgoose
IPC分类号： B01D59/44 , B01D59/46 , B01D59/50 , H01J49/26 , H01J49/36 , G01N27/62 , H01J49/42 , H01J49/06
CPC分类号： H01J49/36 , G01N27/624 , H01J49/06 , H01J49/42 , H01J49/426
摘要： An ion mobility separator or spectrometer is disclosed comprising an inner cylinder and an outer cylinder defining an annular volume through which ions are transmitted. Spiral electrodes a-f are arranged on a surface of the inner cylinder and/or on a surface of the outer cylinder. A first device is arranged and adapted to maintain a DC electric field and/or a pseudo-potential force which acts to urge ions from a first end of the ion mobility separator or spectrometer to a second end of the ion mobility separator or spectrometer. A second device is arranged and adapted to apply transient DC voltages to the one or more spiral electrodes in order to urge ions towards the first end of the ion mobility separator or spectrometer. The net effect is to extend the effective path length of the ion mobility separator.
摘要翻译：公开了一种离子迁移率分离器或光谱仪，其包括限定通过离子传播的环形体积的内圆筒和外圆筒。螺旋电极a-f布置在内筒的表面上和/或外筒的表面上。第一装置被布置和适于维持DC电场和/或伪电势力，其用于将离子从离子迁移率分离器或光谱仪的第一端推动到离子迁移率分离器或光谱仪的第二端。第二装置被布置并适于将瞬态DC电压施加到一个或多个螺旋电极，以便促使离子朝向离子迁移率分离器或光谱仪的第一端。净效应是延长离子迁移率分离器的有效路径长度。

8. 发明申请

US20090014646A1 Method and apparatus for incorporating electrostatic concentrators and/or ion mobility separators with Raman, IR, UV, XRF, LIF and LIBS spectroscopy and /or other spectroscopic techniques 有权
标题翻译：使用拉曼，IR，UV，XRF，LIF和LIBS光谱学和/或其他光谱技术并入静电浓缩器和/或离子迁移率分离器的方法和装置
公开(公告)号：US20090014646A1
公开(公告)日：2009-01-15
申请号：US11706043
申请日：2007-02-13
申请人： Daryoosh Vakhshoori , Peili Chen
发明人： Daryoosh Vakhshoori , Peili Chen
IPC分类号： B01D59/46
CPC分类号： G01N15/0205 , G01N15/0266 , G01N15/0612 , G01N21/31 , G01N21/65 , G01N21/718 , G01N21/85 , G01N2001/4038 , G01N2021/8411 , G01N2021/8477
摘要： The present invention provides a novel approach for reliably and accurately detecting and identifying airborne particles. This is done by providing a novel system which incorporates electrostatic concentrators and/or ion mobility separators with Raman, IR, UV, XRF, LIF and LIBS spectroscopy and/or other spectroscopic techniques.
摘要翻译：本发明提供了可靠且准确地检测和识别空气中的颗粒的新方法。这是通过提供一种新颖的系统，其结合具有拉曼，IR，UV，XRF，LIF和LIBS光谱学和/或其他光谱技术的静电浓缩器和/或离子迁移率分离器。

9. 发明申请

US20080290272A1 MASS SPECTROSCOPY DEVICE AND MASS SPECTROSCOPY SYSTEM 失效
标题翻译：大众光谱仪器和质谱系统
公开(公告)号：US20080290272A1
公开(公告)日：2008-11-27
申请号：US12126067
申请日：2008-05-23
申请人： Masayuki NAYA , Jingbo Li
发明人： Masayuki NAYA , Jingbo Li
IPC分类号： B01D59/46
CPC分类号： H01J49/164
摘要： A mass spectroscopy device constituted by a first reflector which is partially transparent and partially reflective, a transparent body, and a second reflector which is reflective. The first reflector and the second reflector are arranged on opposite sides of the transparent body so as to form an optical resonator in such a manner that when a specimen containing an analyte subject to mass spectroscopy is arranged in contact with a surface of the first reflector, and the surface is irradiated with measurement light, optical resonance occurs in the optical resonator, and intensifies an electric field on the surface, and the intensified electric field desorbs the analyte from the surface.
摘要翻译：一种由部分透明和部分反射的第一反射器，透明体和反射性的第二反射器构成的质谱仪。第一反射器和第二反射器布置在透明体的相对侧上，以便形成光学谐振器，使得当含有质谱分析物的样本被布置成与第一反射器的表面接触时，并且用测量光照射表面，在光谐振器中发生光共振，并且强化表面上的电场，并且强化的电场从表面解吸分析物。

10. 发明申请

US20080277579A1 MASS ANALYZING APPARATUS 有权
标题翻译：质量分析仪
公开(公告)号：US20080277579A1
公开(公告)日：2008-11-13
申请号：US11778666
申请日：2007-07-17
申请人： Che-Hsin LIN , Jen-Taie SHIEA , Wei-Jen HSU , Liang-Tsuen CHEN
发明人： Che-Hsin LIN , Jen-Taie SHIEA , Wei-Jen HSU , Liang-Tsuen CHEN
IPC分类号： B01D59/46
CPC分类号： H01J49/12
摘要： The present invention relates to a mass analyzing apparatus, comprising a first metal electrode plate, a second metal electrode plate, an RF power supply, a reactant gas and a mass spectrometry. The second metal electrode plate is grounded. There is a gap between the first metal electrode plate and the second metal electrode plate. The RF power supply is electrically connected to the first metal electrode plate. Electric discharge is caused between the first metal electrode plate and the second metal electrode plate, so that the reactant gas becomes dissociation plasma. The dissociation plasma reacts with a gas analyte from a sample and then enters the mass spectrometry for a mass analysis. In addition, since the dissociation plasma is generated under low temperature and atmospheric pressure, the mass analyzing apparatus of the present invention is applicable for biological samples that need to be analyzed at a low temperature.
摘要翻译：本发明涉及一种质量分析装置，包括第一金属电极板，第二金属电极板，RF电源，反应气体和质谱。第二金属电极板接地。在第一金属电极板和第二金属电极板之间存在间隙。 RF电源电连接到第一金属电极板。在第一金属电极板和第二金属电极板之间产生放电，使得反应气体变为解离等离子体。解离等离子体与来自样品的气体分析物反应，然后进入质谱进行质量分析。此外，由于解离等离子体在低温和大气压下产生，本发明的质量分析装置适用于需要在低温下分析的生物样品。

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