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1. 发明申请

US20070039616A1 Portable liquid oxygen delivery system 有权
标题翻译：便携式液氧输送系统
公开(公告)号：US20070039616A1
公开(公告)日：2007-02-22
申请号：US11493151
申请日：2006-07-26
申请人： Roy Hughes , Jonathan McLellan , Margaret McLellan
发明人： Roy Hughes , Jonathan McLellan , Margaret McLellan
IPC分类号： A62B7/06 , B65B1/04 , F17C7/02
CPC分类号： F17C7/02 , F17C6/00 , F17C7/04 , F17C9/00 , F17C2201/0109 , F17C2201/032 , F17C2201/056 , F17C2201/058 , F17C2203/0391 , F17C2205/0157 , F17C2205/0165 , F17C2205/0169 , F17C2205/0308 , F17C2205/0332 , F17C2221/011 , F17C2223/0161 , F17C2223/033 , F17C2223/047 , F17C2227/0311 , F17C2250/01 , F17C2250/034 , F17C2250/036 , F17C2250/0413 , F17C2250/043 , F17C2250/0439 , F17C2250/0443 , F17C2250/0452 , F17C2250/075 , F17C2270/025 , Y10S128/27
摘要： A portable liquid oxygen medical delivery system including a portable liquid oxygen delivery apparatus and a portable liquid oxygen recharger. The portable liquid oxygen delivery apparatus contains an initial quantity of liquid oxygen. The liquid oxygen delivery apparatus is sufficiently lightweight for portability by an ambulatory patient and has a fill port for receiving liquid oxygen. The liquid oxygen recharger stores a supplemental quantity of liquid oxygen and is also sufficiently lightweight for portability by an ambulatory individual. The liquid oxygen recharger has an interface for interfacing the liquid oxygen recharger with the portable liquid oxygen delivery apparatus for delivering the supplemental quantity of liquid oxygen to the portable liquid oxygen delivery apparatus.
摘要翻译：一种便携式液氧医疗输送系统，包括便携式液氧输送装置和便携式液氧充气器。便携式液氧输送装置含有初始量的液氧。液体氧输送装置足够轻便，由便携式患者携带，并具有用于接收液氧的填充口。液体充氧器存储补充量的液氧，并且对于移动个体的便携性也是足够轻的。液体充氧器具有用于将液体充氧器与便携式液氧输送装置连接的接口，用于将补充量的液氧输送到便携式液氧输送装置。

2. 发明申请

US20050098174A1 Portable liquid oxygen unit with multiple operational orientations 有权
标题翻译：便携式液氧机组，具有多种操作方向
公开(公告)号：US20050098174A1
公开(公告)日：2005-05-12
申请号：US11008134
申请日：2004-12-10
申请人： Mark Frye , Leonardo Toma , Richard Remes
发明人： Mark Frye , Leonardo Toma , Richard Remes
IPC分类号： A61M16/10 , F17C3/08 , F17C9/02 , F17C13/00 , F17C13/08 , A62B7/00 , F25J3/00
CPC分类号： F17C13/006 , F17C3/08 , F17C7/04 , F17C9/02 , F17C13/005 , F17C13/084 , F17C2221/011 , F17C2223/0153 , F17C2223/047 , F17C2225/0123 , F17C2260/027 , F17C2270/02 , F17C2270/025 , Y10S128/27
摘要： A portable liquid oxygen (LOX) storage/delivery apparatus is provided, including an insulated (LOX) container having an interior, a bottom portion and a sidewall, the sidewall including a first side portion and a second side portion, both extending between the top portion and the bottom portion, and a port system in communication with the interior of the container for charging the container and for withdrawing LOX and gaseous oxygen from the container. The gaseous oxygen is withdrawn from the container through a first outlet and LOX is withdrawn from the container through a second outlet. Gaseous oxygen can be withdrawn from the container through the first outlet and LOX can be withdrawn from the container through the second outlet when the container is positioned in a first orientation with the sidewall vertically oriented, as well as when the container is positioned in a second orientation with the second side portion oriented downwardly and with the first side portion oriented upwardly and overlying the second side portion, and any position in between.
摘要翻译：提供便携式液氧（LOX）储存/输送装置，其包括具有内部，底部和侧壁的绝缘（LOX）容器，所述侧壁包括第一侧部和第二侧部，两者在顶部部分和底部，以及与容器内部连通的端口系统，用于对容器充电并从容器中取出LOX和气态氧。气态氧通过第一出口从容器中排出，LOX通过第二出口从容器中取出。气体氧可以通过第一出口从容器中取出，并且当容器定位在侧壁垂直定向的第一方位时，以及当容器位于第二出口处时，LOX可以通过第二出口从容器中取出其中第二侧部分向下取向并且第一侧部分向上取向并覆盖第二侧部，以及其间的任何位置。

3. 发明申请

US20020029034A1 METHOD AND APPARATUS FOR RUPTURING TARGETED CELLS 失效
标题翻译：破坏目标细胞的方法和装置
公开(公告)号：US20020029034A1
公开(公告)日：2002-03-07
申请号：US09188915
申请日：1998-11-09
发明人： PROSERFINA R. TORTAL , GRACE TORTAL-QUIRONG , ROLANDO A. QUIRONG , ELEAZAR R. TORTAL , JOCELYN FONACIER TORTAL
IPC分类号： A61B018/02
CPC分类号： A61B18/02 , A61B2018/0262 , Y10S128/27
摘要： A probe contacts targeted tissue, sometimes while positioned adjacent to nontargeted live tissues. In preferred forms, the probe includes a support that only minimally conducts heat from nontargeted tissues. A very conductive targeted-tissue-contacting element, at an end of the support, is immersed in a liquid cryogen (preferably nitrogen) and then removed for contacting with (e. g., insertion into) the targeted tissue. An ultrathin highly thermoconductive polymeric tubing holds both a very conductive, cold material, forming the targeted-tissue-contacting element, and fine insulating material (e. g. highly insulating elastomer) forming part of the support. The targeted-tissue-contacting element is fashioned to fit the targeted tissue in at least one dimension, and the support to fit nontargeted live tissues (if any) adjacent to which the probe is positioned while contacting the targeted tissue. The probe provides for confined heat exchange with the targeted tissue - as by matching dimensions of probe and targeted tissue, or of support and nontargeted tissue, or insulating the support against heat flow into the probe or from nontargeted tissues; and preferably all of these. The best targeted-tissue-contacting element is a solid cryogen, roughly at liquid-nitrogen temperature; ideally it is solid carbon dioxide, particularly super-sublimated carbon dioxide - cooled to a temperature range characterized by extremely tight crystal bonds.
摘要翻译：探针接触目标组织，有时位于非靶向活组织附近。在优选形式中，探针包括仅从非靶向组织最低限度地传导热量的支架。将支撑体末端的非常导电的靶向组织接触元件浸入液体冷冻剂（优选氮气）中，然后除去以与（例如，插入）目标组织接触。超薄高导热聚合物管保持形成目标组织接触元件的非常导电的冷材料和形成支撑体的一部分的精细绝缘材料（例如高度绝缘的弹性体）。靶向组织接触元件的形状是将目标组织装配在至少一个维度上，并且支撑件适合与探针定位的邻近的非靶向活组织（如果有的话）接触目标组织。探针提供与目标组织的局限热交换，如通过匹配探针和靶组织，支撑和非靶向组织的尺寸，或绝缘支撑物抵抗探针或非靶向组织的热流; 并且优选所有这些。最好的靶组织接触元件是固体冷冻剂，大致处于液氮温度; 理想情况下，它是固体二氧化碳，特别是超升华的二氧化碳，被冷却到以非常紧密的结晶键为特征的温度范围。

4. 发明授权

US6015390A System and method for stabilizing and removing tissue 失效
标题翻译：用于稳定和去除组织的系统和方法
公开(公告)号：US6015390A
公开(公告)日：2000-01-18
申请号：US96807
申请日：1998-06-12
申请人： David N. Krag
发明人： David N. Krag
IPC分类号： A61B17/00 , A61B18/02 , A61B19/00 , A61B5/00
CPC分类号： A61B18/02 , A61B90/17 , A61B2017/00084 , A61B2090/374 , A61B2090/3908 , A61B34/10 , Y10S128/27
摘要： A system (8) and method for stabilizing a tissue mass, using temperature sensors (10), a scanner (80), and a cryoprobe (220). The sensors provide temperature information with respect to a tissue portion adjacent thereto. The sensors include an identification (ID) code and an ID decoder. The ID decoder compares the sensor ID code to an ID code contained in an interrogation signal provided by the scanner. If the codes match, the sensor transmits the temperature information to the scanner, which processes and displays the temperature information in a humanly recognizable form. The method includes the step of inserting a cryoprobe into a tissue volume to be stabilized so that a portion of the cryoprobe projects therefrom. Then, the tissue volume is frozen while monitoring the size or temperature of the tissue volume. Freezing is terminated when the tissue volume is frozen (or reaches a first temperature level), and then removed while grasping the cryoprobe so as to stabilize the tissue volume.
摘要翻译：一种使用温度传感器（10），扫描器（80）和冷冻探针（220）来稳定组织块的系统（8）和方法。传感器提供关于与其相邻的组织部分的温度信息。传感器包括识别（ID）码和ID解码器。 ID解码器将传感器ID代码与扫描器提供的询问信号中包含的ID码进行比较。如果代码匹配，传感器将温度信息传送到扫描仪，扫描仪以人类可识别的形式处理和显示温度信息。该方法包括将冷冻探针插入要稳定的组织体积中以使得一部分冷冻探针从其突出的步骤。然后，在监测组织体积的大小或温度的同时冷冻组织体积。当组织体积冷冻（或达到第一温度水平）时，冷冻终止，然后在抓住冷冻探针时移除，以便稳定组织体积。

5. 发明授权

US4823790A Cryogenic-and-ultrasonic scalpel 失效
标题翻译：低温超声手术刀
公开(公告)号：US4823790A
公开(公告)日：1989-04-25
申请号：US55168
申请日：1987-05-28
申请人： Boris I. Alperovich , Ljutsia Paramonova , Gennady Tjulkov , Valery I. Soloviev , Alexandr I. Paramonov
发明人： Boris I. Alperovich , Ljutsia Paramonova , Gennady Tjulkov , Valery I. Soloviev , Alexandr I. Paramonov
IPC分类号： A61B18/00 , A61B17/22 , A61B17/32 , A61B18/02 , A61B18/12 , F25B19/00 , A61B17/36
CPC分类号： A61B17/320068 , A61B17/22012 , A61B17/32 , A61B18/0206 , F25B19/005 , Y10S128/27
摘要： A cryogenic-and-ultrasonic scalpel includes a body, a source of ultrasonic vibrations positioned within the body, a hollow, frusto conical transformer connected to the source of ultrasonic vibrations, and a tubular heat exchanger for supplying refrigerant to the scalpel blade and draining the same therefrom the heat exchanger including inner and outer fluidly intercommunicating coaxial tubes, with the blade and the transformer connected to the outer tube, and ultrasonic vibrations being imparted to the outer tube and then to the blade through the transformer, and with refrigerant supplied through the inner tube, out from holes in the outer tube onto the inner side of the blade, and drained through the outer tube.
摘要翻译：一种低温超声手术刀包括主体，定位在体内的超声波振动源，连接到超声波振动源的中空截头圆锥形变压器，以及用于将冷冻剂供应到手术刀刀片并将同样地，热交换器包括内部和外部流体连通的同轴管，其中叶片和变压器连接到外管，并且超声波振动被施加到外管，然后通过变压器施加到叶片，并且通过内管，从外管中的孔排出到叶片的内侧，并通过外管排出。

6. 发明授权

US2990695A Thermodynamic transfer systems 失效
标题翻译：热力传递系统
公开(公告)号：US2990695A
公开(公告)日：1961-07-04
申请号：US76539958
申请日：1958-10-06
申请人： BENDIX CORP
发明人： LEFFINGWELL JR DWIGHT A
IPC分类号： B64D13/06
CPC分类号： B64D13/06 , B64D2013/0637 , F25B2347/021 , Y02T50/56 , Y10S128/27

7. 发明授权

US08256415B2 Portable liquid oxygen delivery system 有权
标题翻译：便携式液氧输送系统
公开(公告)号：US08256415B2
公开(公告)日：2012-09-04
申请号：US12774904
申请日：2010-05-06
申请人： Roy A. Hughes , Jonathan C. McLellan , Margaret McLellan, legal representative , Douglas Whitcher
发明人： Roy A. Hughes , Jonathan C. McLellan , Douglas Whitcher
IPC分类号： A61M11/00
CPC分类号： F17C7/02 , F17C6/00 , F17C7/04 , F17C9/00 , F17C2201/0109 , F17C2201/032 , F17C2201/056 , F17C2201/058 , F17C2203/0391 , F17C2205/0157 , F17C2205/0165 , F17C2205/0169 , F17C2205/0308 , F17C2205/0332 , F17C2221/011 , F17C2223/0161 , F17C2223/033 , F17C2223/047 , F17C2227/0311 , F17C2250/01 , F17C2250/034 , F17C2250/036 , F17C2250/0413 , F17C2250/043 , F17C2250/0439 , F17C2250/0443 , F17C2250/0452 , F17C2250/075 , F17C2270/025 , Y10S128/27
摘要： A portable liquid oxygen medical delivery system including a portable liquid oxygen delivery apparatus and a portable liquid oxygen recharger. The portable liquid oxygen delivery apparatus contains an initial quantity of liquid oxygen. The liquid oxygen delivery apparatus is sufficiently lightweight for portability by an ambulatory patient and has a fill port for receiving liquid oxygen. The liquid oxygen recharger stores a supplemental quantity of liquid oxygen and is also sufficiently lightweight for portability by an ambulatory individual. The liquid oxygen recharger has an interface for interfacing the liquid oxygen recharger with the portable liquid oxygen delivery apparatus for delivering the supplemental quantity of liquid oxygen to the portable liquid oxygen delivery apparatus.
摘要翻译：一种便携式液氧医疗输送系统，包括便携式液氧输送装置和便携式液氧充气器。便携式液氧输送装置含有初始量的液氧。液体氧输送装置足够轻便，由便携式患者携带，并具有用于接收液氧的填充口。液体充氧器存储补充量的液氧，并且对于移动个体的便携性也是足够轻的。液体充氧器具有用于将液体充氧器与便携式液氧输送装置连接的接口，用于将补充量的液氧输送到便携式液氧输送装置。

8. 发明申请

US20070186925A1 Apparatus for Drawing a Cryogenic Liquid from a Container 有权
标题翻译：从容器中抽取低温液体的装置
公开(公告)号：US20070186925A1
公开(公告)日：2007-08-16
申请号：US11673046
申请日：2007-02-09
申请人： Clayton E. Blalock
发明人： Clayton E. Blalock
IPC分类号： F17C7/04 , F17C13/00 , A62B7/00 , A62B7/06 , A61M16/00
CPC分类号： A62B7/06 , F17C3/08 , F17C6/00 , F17C9/02 , F17C2201/0104 , F17C2201/032 , F17C2201/035 , F17C2201/037 , F17C2201/058 , F17C2203/0391 , F17C2203/0629 , F17C2205/0352 , F17C2205/0361 , F17C2205/0364 , F17C2221/031 , F17C2223/0161 , F17C2223/033 , F17C2223/047 , F17C2225/0123 , F17C2225/033 , F17C2227/0107 , F17C2227/0302 , F17C2227/0388 , F17C2227/0393 , F17C2260/035 , F17C2270/025 , Y10S128/27
摘要： An embodiment of the invention comprises an apparatus or system for withdrawing a cryogenic liquid from a container wherein the liquid may be drawn from the container independent of the orientation of the container. The apparatus comprises a conduit having a flexible metallic hose portion and a metallic head. The flexible hose portion has a first end in fluid communication with an outlet portal of the container and a second end to which the head is attached.
摘要翻译：本发明的实施例包括用于从容器中取出低温液体的装置或系统，其中液体可以独立于容器的取向从容器中抽出。该装置包括具有柔性金属软管部分和金属头部的导管。柔性软管部分具有与容器的出口入口流体连通的第一端和头部附接到的第二端。

9. 发明授权

US06742517B1 High efficiency liquid oxygen system 有权
标题翻译：高效液氧系统
公开(公告)号：US06742517B1
公开(公告)日：2004-06-01
申请号：US09696170
申请日：2000-10-26
申请人： Mark R. Frye , Leonardo S. Toma , Richard A. Davis
发明人： Mark R. Frye , Leonardo S. Toma , Richard A. Davis
IPC分类号： A62B706
CPC分类号： F17C7/02 , F17C2201/0114 , F17C2201/0119 , F17C2201/058 , F17C2203/0391 , F17C2205/0146 , F17C2205/0332 , F17C2221/011 , F17C2223/0123 , F17C2223/0153 , F17C2223/033 , F17C2250/043 , F17C2250/072 , F17C2270/025 , Y10S128/27
摘要： A high-efficiency liquid oxygen, (LOX) storage/delivery system utilizes a portable LOX/delivery apparatus with a portable LOX container. A portable-unit LOX transfer connector is connected to the portable LOX container and is connectable to a main source of LOX in a primary reservoir LOX container. A portable-unit oxygen gas transfer connector is provided for transferring oxygen gas from the portable LOX container to an oxygen gas delivery device for delivering oxygen gas to a patient. An inter-unit oxygen gas transfer connector also is provided for connecting the portable apparatus to a stationary source of oxygen gas in the primary reservoir container, for transferring oxygen gas to the portable apparatus. A portable-unit primary relief valve is connected to the portable LOX container for venting oxygen gas out of the portable LOX container when pressure in the portable LOX container reaches a predetermined level. When the inter-unit oxygen gas transfer connector of the portable container is connected to the stationary source of oxygen in the primary reservoir container, oxygen gas can be transferred to the oxygen gas delivery device for delivery to the patient from the portable LOX container while oxygen gas is transferred to the portable container from the stationary source of gas in the primary reservoir LOX container.
摘要翻译：高效液氧（LOX）储存/输送系统利用便携式LOX /输送装置与便携式LOX容器。便携式单元LOX传输连接器连接到便携式LOX容器，并且可连接到主容器LOX容器中的主要LOX源。提供便携式氧气输送连接器，用于将氧气从便携式LOX容器转移到用于将氧气输送给患者的氧气输送装置。还提供一种单元间氧气传输连接器，用于将便携式设备连接到主储存容器中的固定的氧气源，用于将氧气输送到便携式设备。便携式主安全阀连接到便携式LOX容器，用于在便携式LOX容器中的压力达到预定水平时将氧气排出便携式LOX容器。当便携式容器的单元间氧气传输连接器连接到主储存容器中的固定的氧气源时，可以将氧气转移到氧气输送装置，以从便携式LOX容器输送到患者，同时氧气气体从主容器LOX容器中的固定气体源转移到便携式容器。

10. 发明授权

US06508814B2 Method and apparatus for rupturing targeted cells 失效
标题翻译：用于破坏靶细胞的方法和装置
公开(公告)号：US06508814B2
公开(公告)日：2003-01-21
申请号：US09188915
申请日：1998-11-09
申请人： Proserfina R. Tortal , Grace Tortal-Quirong , Rolando A. Quirong , Eleazar R. Tortal , Jocelyn F. Tortal
发明人： Proserfina R. Tortal , Grace Tortal-Quirong , Rolando A. Quirong , Eleazar R. Tortal , Jocelyn F. Tortal
IPC分类号： A61B1818
CPC分类号： A61B18/02 , A61B2018/0262 , Y10S128/27
摘要： A probe contacts targeted tissue, sometimes while positioned adjacent to nontargeted live tissues. In preferred forms, the probe includes a support that only minimally conducts heat from nontargeted tissues. A very conductive targeted-tissue-contacting element, at an end of the support, is immersed in a liquid cryogen (preferably nitrogen) and then removed for contacting with (e. g., insertion into) the targeted tissue. An ultrathin highly thermoconductive polymeric tubing holds both a very conductive, cold material, forming the targeted-tissue-contacting element, and fine insulating material (e. g. highly insulating elastomer) forming part of the support. The targeted-tissue-contacting element is fashioned to fit the targeted tissue in at least one dimension, and the support to fit nontargeted live tissues (if any) adjacent to which the probe is positioned while contacting the targeted tissue. The probe provides for confined heat exchange with the targeted tissue—as by matching dimensions of probe and targeted tissue, or of support and nontargeted tissue, or insulating the support against heat flow into the probe or from nontargeted tissues; and preferably all of these. The best targeted-tissue-contacting element is a solid cryogen, roughly at liquid-nitrogen temperature; ideally it is solid carbon dioxide, particularly super-sublimated carbon dioxide—cooled to a temperature range characterized by extremely tight crystal bonds.
摘要翻译：探针接触目标组织，有时位于非靶向活组织附近。在优选形式中，探针包括仅从非靶向组织最低限度地传导热量的支架。将支撑体末端的非常导电的靶向组织接触元件浸入液体冷冻剂（优选氮气）中，然后除去以与（例如，插入）目标组织接触。超薄高导热聚合物管保持形成目标组织接触元件的非常导电的冷材料和形成支撑体的一部分的精细绝缘材料（例如高度绝缘的弹性体）。靶向组织接触元件的形状是将目标组织装配在至少一个维度上，并且支撑件适合与探针定位的邻近的非靶向活组织（如果有的话）接触目标组织。探针提供与目标组织的局限热交换，如通过匹配探针和靶组织或支撑和非靶向组织的尺寸，或绝缘支撑件抵抗热流入探针或非靶向组织; 并且优选所有这些。最好的靶组织接触元件是固体冷冻剂，大致处于液氮温度; 理想情况下，它是固体二氧化碳，特别是超升华的二氧化碳，冷却到特征在于非常紧密的结晶键的温度范围。

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