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1. 发明授权

US12130268B2 System for electrospray ionization with integrated lc column and electrospray emitter 有权
公开(公告)号：US12130268B2
公开(公告)日：2024-10-29
申请号：US18341712
申请日：2023-06-26
申请人： DIONEX CORPORATION
发明人： Brandon Howard Robson , Xuefei Sun , Carla Marie Medlin , Shane Bechler
IPC分类号： G01N30/00 , G01N30/60 , G01N30/72 , H01J49/04 , H01J49/16
CPC分类号： G01N30/7266 , G01N30/6004 , G01N30/6047 , H01J49/0445 , H01J49/167
摘要： An integrated system for liquid separation and electrospray ionization includes an emitter-enabled capillary column including an emitter portion and a column portion; and a retractable protective sleeve for covering and/or supporting the emitter portion along at least a portion of its axis. The protective sleeve is mounted around the emitter-enabled capillary column. The retractable protective sleeve is moveable to an extended position wherein a tip of the emitter portion is covered by the protective sleeve. A resilient member is provided to bias the protective sleeve towards the extended position. The protective sleeve is enclosed and moveable within an outer electrically conductive sheath adapted for insertion within a holder having a high-voltage contact point. The sheath is adapted to contact the high-voltage contact point and provide an electrical connection to enable the emitter-enabled capillary column to receive a high voltage. The sheath has a recess to receive the high-voltage contact point.

2. 发明授权

US12050209B2 Vacuum liquid extraction and purification systems and methods 有权
公开(公告)号：US12050209B2
公开(公告)日：2024-07-30
申请号：US17178985
申请日：2021-02-18
申请人： Fluid Management Systems, Inc.
发明人： Hamid Shirkhan , Dirk P. Ten Broeck , Joseph C. Caruso , Yijun Yang , Rashid M. Juma , Thomas G. Hall
IPC分类号： G01N30/52 , A61M39/10 , B01D15/18 , B01D15/22 , G01N30/02 , G01N30/46 , G01N30/60
CPC分类号： G01N30/52 , A61M39/10 , B01D15/1871 , B01D15/22 , G01N30/465 , G01N30/468 , G01N30/6043 , G01N30/6047 , B01D2215/022 , G01N2030/027 , G01N2030/522
摘要： The invention features compact systems and methods for vacuum liquid purification and extraction of a liquid sample.

3. 发明授权

US11921093B2 Mounting a sample separation unit by a swivel mechanism 有权
公开(公告)号：US11921093B2
公开(公告)日：2024-03-05
申请号：US17584250
申请日：2022-01-25
申请人： Agilent Technologies, Inc.
发明人： Daniela Loraing , Lena Höninger , Uwe Effelsberg , Andreas Otto , Ansgar Waldbaur , Armin Steinke , Thomas Ortmann , Michael Lang
IPC分类号： G01N30/60
CPC分类号： G01N30/6047
摘要： A mounting device for mounting a sample separation unit configured for separating, preferably chromatographically separating, compounds in a fluidic sample includes a first fluid connector configured for being mechanically and fluidically coupled with a first fluid interface of the sample separation unit, a second fluid connector configured for being mechanically and fluidically coupled with a second fluid interface of the sample separation unit, and a swivel mechanism configured for swivelling the first fluid connector between a mounting orientation for mounting the first fluid interface of the sample separation unit at the first fluid connector and an alignment orientation for aligning the second fluid interface of the mounted sample separation unit with the second fluid connector for subsequently coupling the second fluid interface with the second fluid connector.

4. 发明授权

US11845059B2 Chromatographic cassette 有权
公开(公告)号：US11845059B2
公开(公告)日：2023-12-19
申请号：US17871086
申请日：2022-07-22
申请人： SPF Technologies LLC
发明人： Gaston de los Reyes
IPC分类号： B01D15/20 , B01J20/28 , B01J20/281 , B01J20/282 , G01N30/52 , G01N30/60 , B33Y10/00 , B33Y80/00 , B01D15/22
CPC分类号： B01J20/281 , B01D15/206 , B01D15/22 , B33Y10/00 , B33Y80/00 , G01N30/52 , G01N30/6043 , G01N30/6047 , B01J20/282 , B01J20/28016 , B01J20/28042 , G01N30/6069 , G01N30/6095 , G01N2030/527 , G01N2030/528
摘要： A chromatographic cassette includes a cassette including a chamber, chromatographic media disposed within the cassette chamber, a distribution network fluidly coupled to the chromatographic media and an inlet port and an outlet port coupled to the distribution network. A hyper-productive chromatography technique includes providing a scalable and stackable chromatographic cassette, loading a sample to be processed, operating the scalable chromatographic cassette having an adsorptive chromatographic bed having a volume greater than 0.5 liter by establishing a flow at a linear velocity greater than 500 cm/hr with a residence time of the loading step of less than one minute.

5. 发明授权

US11761933B2 Fluid supply device for fluid chromatograph 有权
公开(公告)号：US11761933B2
公开(公告)日：2023-09-19
申请号：US17054980
申请日：2019-01-17
申请人： SHIMADZU CORPORATION
发明人： Tomoki Hiraoka , Toshiki Sano
IPC分类号： G01N30/60 , B01D15/14 , G01N30/30 , G01N30/32 , B01D15/40
CPC分类号： G01N30/6047 , B01D15/14 , G01N30/30 , G01N30/32 , B01D15/40 , G01N2030/326
摘要： A fluid supply device for a fluid chromatograph includes a storage container, a pump device, a filter, a guide and a heat dissipation device. The pump device supplies a mobile phase to a column. The storage container stores the pump device and the filter and has an intake port. The guide guides gas that has been introduced into the storage container through the intake port to the filter. A heat dissipation device dissipates heat generated from the pump device to the outside of the storage container together with the gas inside of the storage container. The storage container includes a door having a front surface directed forwardly of the fluid supply device. The intake port is provided at the door to be directed sidewardly of the fluid supply device.

6. 发明授权

US10281441B1 Clamp for chromatography columns 有权
公开(公告)号：US10281441B1
公开(公告)日：2019-05-07
申请号：US15858871
申请日：2017-12-29
申请人： BIO-RAD LABORATORIES, INC.
发明人： David Lerner
IPC分类号： G01N30/60
CPC分类号： G01N30/6047 , G01N30/461 , G01N30/6034 , G01N30/6039
摘要： A clamp for chromatography columns has a first seal with a first opening a movable seal with a second opening and a movable coupler. The movable coupler has first and second coupler seals with communicating third and fourth openings. The clamp is arranged for pressing a first chromatography column between the first seal and the first coupler seal and for pressing a second chromatography column between the movable seal and the second coupler seal, such that the first opening fluidly communicates with the second opening through the first chromatography column, the third and fourth openings and the second chromatography column.

7. 发明申请

US20180088092A1 SORBENT TUBE HOLDER 审中-公开
公开(公告)号：US20180088092A1
公开(公告)日：2018-03-29
申请号：US15567593
申请日：2016-04-18
申请人： EnDet Limited
发明人： Jeremy Knight , Tom Knight
IPC分类号： G01N30/60 , B01L9/06 , B01L9/00 , G01N1/22
CPC分类号： G01N30/6047 , B01L9/06 , B01L9/50 , B01L2200/025 , B01L2200/026 , B01L2200/08 , B01L2200/18 , G01N1/2214 , G01N30/6091 , G01N2030/8868 , G01N2030/8872
摘要： A sorbent tube holder (100) for securing a sorbent tube (10) in position in a fluid-flow system, the sorbent tube holder (100) comprising: an mounting element (126) having first and second opposed ends (126a, 126b) which define a tube mounting axis (A-A); at least one fastener (128) in communication with the mounting element (126) for providing a releasable tube retaining force; at least one sorbent tube (10) engaged with the mounting element (126); and a holder frame (130) to which the mounting element (126) is attached to prevent or limit movement of the mounting element (126) perpendicular to the tube mounting axis. A method of preventing or limiting unintentional damage to a sorbent tube, and a portable tube holder are also provided.

8. 发明申请

US20170182433A1 STACKABLE PLANAR ADSORPTIVE DEVICES 审中-公开
公开(公告)号：US20170182433A1
公开(公告)日：2017-06-29
申请号：US15456484
申请日：2017-03-11
申请人： SPF Technologies LLC
发明人： Gaston de los Reyes
IPC分类号： B01D15/22 , B01J20/281 , B33Y10/00 , G01N30/46 , B01D15/20 , B33Y80/00
CPC分类号： B01D15/22 , B01D15/1842 , B01D15/206 , B01J20/28016 , B01J20/28042 , B01J20/282 , B33Y10/00 , B33Y80/00 , G01N30/482 , G01N30/52 , G01N30/6043 , G01N30/6047 , G01N30/6069 , G01N30/6095 , G01N2030/527 , G01N2030/528
摘要： A lattice and distribution network for a stackable chromatography cassette comprising: a peripheral seal; at least one screen forming the lattice surrounded by the peripheral seal, each at least one screen comprising a plurality of struts in a latticed arrangement; a first internal distribution network fluidly coupled to the lattice and surrounded by the peripheral seal; a second internal distribution network disposed opposite the first internal distribution network, fluidly coupled to the lattice and surrounded by the peripheral seal; wherein a direction of fluid flow is established from the first internal distribution network through the lattice to the second internal distribution network; and wherein preferential streamlines are minimized.

9. 发明申请

US20170120251A1 COLUMN ATTACHMENT DEVICE 审中-公开
公开(公告)号：US20170120251A1
公开(公告)日：2017-05-04
申请号：US15311584
申请日：2014-05-16
申请人： Shimadzu Corporation
发明人： Hirokazu TANIUCHI , Hajime TAKEMOTO , Shoji IDE , Yasunori TERAI , Ryo TAKECHI
IPC分类号： B01L9/00 , B01D53/02 , G01N30/60
CPC分类号： B01L9/50 , B01D53/025 , G01N30/6004 , G01N30/6026 , G01N30/6047 , G01N2030/025
摘要： A ferrule 10 is pressed by a pressing plate 35, and the ferrule 10 is thereby sandwiched and fixed between a ferrule receiving part 20 and ferrule pressing part 30. The pressing plate 35 is displaced by a displacing mechanism 350, whereby the pressing plate 35 is switched between a contacting state in which the pressing plate 35 is in contact with the ferrule 10 and a non-contacting state in which the pressing plate 35 is not in contact with the ferrule 10 and the ferrule 10 can pass thorough the inside of the ferrule pressing part 30. By displacement of the pressing plate 35 to the non-contacting state, the ferrule pressing part 30 can be extracted from the ferrule 10 side, and the ferrule pressing part 30 can therefore be removed from a column 2 in a state in which the ferrule 10 is attached in a swaged fashion.

10. 发明申请

US20170030872A1 HOISTING AND HOLDING SYSTEM FOR CHROMATOGRAPHY COLUMN 审中-公开
标题翻译：色谱柱的放置和保存系统
公开(公告)号：US20170030872A1
公开(公告)日：2017-02-02
申请号：US15303095
申请日：2015-03-30
申请人： GE Healthcare Bio-Sciences AB
发明人： Manoj Ramakrishna , Kishore Chengalvarayan , Nikhil Kamble
IPC分类号： G01N30/60 , B01D15/22
CPC分类号： G01N30/6047 , B01D15/22 , G01N30/6021 , G01N2030/027
摘要： A holding system for holding and hoisting a chromatography column of one or more chromatography columns is disclosed. The holding system includes an upright member and a plurality of holding members movably arranged along the upright member. A first supporting member is positioned at an end portion of the chromatography column, wherein a holding member of the plurality of holding members is configured to be engaged to the first supporting member. A second supporting member is positioned at another end portion of the chromatography column. A holding member of the plurality of holding members is configured to be engaged to the second supporting member. One or more hoist assisting members may be also present. A hoist assisting member is operatively connected to the holding member engaged to the first supporting member. The hoist assisting member is operable to move the holding member connected to the first supporting member for hoisting the chromatography column.
摘要翻译：公开了用于保持和提升一个或多个色谱柱色谱柱的保持系统。保持系统包括直立构件和沿着直立构件可移动地布置的多个保持构件。第一支撑构件位于色谱柱的端部，其中多个保持构件的保持构件被配置为接合到第一支撑构件。第二支撑构件位于色谱柱的另一端部。多个保持构件的保持构件被构造成与第二支撑构件接合。一个或多个起重机辅助部件也可以存在。升降机辅助构件可操作地连接到与第一支撑构件接合的保持构件。起重辅助构件可操作地移动连接到第一支撑构件的保持构件以提升色谱柱。

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