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    • 8. 发明授权
    • Method for triggering dependent spectra for data acquisition
    • 触发依赖光谱数据采集的方法
    • US09513232B2
    • 2016-12-06
    • US13995816
    • 2011-12-22
    • David M. CoxStephen A. TateMatthias Glueckmann
    • David M. CoxStephen A. TateMatthias Glueckmann
    • H01J49/00G01N23/00H01J49/02
    • G01N23/00H01J49/0031H01J49/0045H01J49/025
    • Methods and systems are provided for triggering an information dependent mass spectrometry scan in real time. A mass spectrometry scan of a separating sample mixture is performed by a mass spectrometer at each time interval of a time period. The mass spectrometer receives the separating sample mixture from a separation device. It is determined at a certain time interval that a received mass spectrometry scan at the time interval and one or more preceding received mass spectrometry scans include two or more time-varying ion signals that represent two or more fragment ion transitions of a known compound. If a characteristic of the two or more time-varying ion signals meets a selection criterion, the mass spectrometer is instructed to perform a dependent mass spectrometry scan of the separating sample mixture for a precursor ion of the known compound at the time interval.
    • 提供了实时触发信息依赖质谱扫描的方法和系统。 分离样品混合物的质谱扫描由质谱仪在每个时间段的每个时间间隔进行。 质谱仪从分离装置接收分离样品混合物。 在一定时间间隔确定在时间间隔和一个或多个先前接收质谱扫描的接收质谱扫描包括表示已知化合物的两个或更多个片段离子转变的两个或更多个时变离子信号。 如果两个或更多个时变离子信号的特征满足选择标准,则指示质谱仪以时间间隔对已知化合物的前体离子进行分离样品混合物的依赖性质谱扫描。