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1. 发明授权

US09925298B2 Porous polymer scaffold useful for tissue engineering in stem cell transplantation 有权
公开(公告)号：US09925298B2
公开(公告)日：2018-03-27
申请号：US15336187
申请日：2016-10-27
申请人： COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH
发明人： Amitava Das , Pratyay Basak , Ramasatyaveni Geesala , Nimai Bar , Neha Raghuvir Dhoke , Komal Kaushik
IPC分类号： A61L27/18 , A61K47/44 , C12N5/00 , A61L27/56 , A61L27/54 , C08G18/10 , C08G18/48 , C08G18/08 , C08J9/26 , C08L71/02 , C08L75/08
CPC分类号： A61L27/18 , A61L27/56 , A61L27/58 , C08G18/14 , C08G18/36 , C08G18/4833 , C08G18/7671 , C08G18/8051 , C08G65/33351 , C08J9/26 , C08J2201/0462 , C08J2205/044 , C08J2205/05 , C08J2207/10 , C08J2300/16 , C08J2375/08 , C08L71/02 , C08L75/08 , C08L2203/02 , C08L2205/04 , C12N2533/30 , C12N2537/10
摘要： The present invention relates to the synthesis of porous polymer scaffold from polyethyleneglycol-polyurethane having castor oil linkages under controlled conditions and their use as stem cell delivery vehicles thereby accelerating the tissue regeneration process. The present invention further studies the biodegradability, stability and biocompatibility of porous polymer scaffolds in various cell lines and primary bone marrow stem cells. Particularly the present invention further relates to the physio-chemical characterization of the porous polymer scaffolds.

2. 发明申请

US20140128554A1 POLYURETHANE RESIN COMPOSITION AND HOLLOW FIBER MEMBRANE MODULE PRODUCED USING SAME 有权
标题翻译：聚氨酯树脂组合物和使用它的中空纤维膜模块
公开(公告)号：US20140128554A1
公开(公告)日：2014-05-08
申请号：US14128677
申请日：2012-05-25
申请人： Masaharu Hirose
发明人： Masaharu Hirose
IPC分类号： C08L75/04
CPC分类号： C08L75/04 , B01D65/08 , B01D69/08 , B01D71/54 , B01D2321/16 , C08G18/4829 , C08G18/6692 , C08G18/8051
摘要： The polyurethane resin composition comprises a main agent (I) which comprises an urethane prepolymer (A) with an isocyanate group terminal and a hardener (II) which comprises an urethane prepolymer (B) with a hydroxyl group terminal, wherein the urethane prepolymer (B) with the hydroxyl group is a product of reaction between a polyol ingredient (a) comprising a castor oil-based polyol (a1) and a polyisocyanate (b) can inhibit the hollow fiber membranes from clogging, regardless of the kind thereof, when the composition is used as a binder for hollow fiber membranes.
摘要翻译：该聚氨酯树脂组合物包含含有具有异氰酸酯基末端的氨基甲酸酯预聚物（A）和包含具有羟基末端的氨基甲酸酯预聚物（B）的固化剂（II）的主剂（I），其中，氨基甲酸酯预聚物）与含有蓖麻油类多元醇（a1）的多元醇成分（a）和多异氰酸酯（b）之间的反应的产物可以抑制中空纤维膜堵塞，而不管其种类如何，当组合物用作中空纤维膜的粘合剂。

3. 发明授权

US06322606B1 Coated granular fertilizer and method for producing same 有权
标题翻译：涂层颗粒肥料及其制备方法
公开(公告)号：US06322606B1
公开(公告)日：2001-11-27
申请号：US09665123
申请日：2000-09-20
申请人： Haruhiko Komoriya , Kazuhiko Maeda , Masayuki Shiota , Yoshi Hirashima , Kentaro Tsutsumi , Mikio Ootani , Yukio Ikeda
发明人： Haruhiko Komoriya , Kazuhiko Maeda , Masayuki Shiota , Yoshi Hirashima , Kentaro Tsutsumi , Mikio Ootani , Yukio Ikeda
IPC分类号： C05G500
CPC分类号： C08G18/36 , C05G3/0029 , C08G18/5021 , C08G18/8051
摘要： The invention relates to a coated granular fertilizer having a film covering fertilizer granules. This film comprises a polyurethane resin prepared by a method comprising the steps of (a) reacting an aromatic polyisocyanate with a first polyol component (i.e., castor oil or a castor oil derivative), thereby to obtain a prepolymer having terminal isocyanate groups in the molecule; and (b) reacting the prepolymer with a second polyol component (i.e., castor oil or a castor oil derivative) and a third polyol component which is an amine having at least two hydroxyl groups in the molecule, thereby to cure the prepolymer and thus to prepare the polyurethane resin. The invention relates to another coated granular fertilizer having a film covering fertilizer granules. This film comprises a urethane resin and aqueous-fluid-absorbing particles having a particle diameter of from 1 to 200 &mgr;m. This urethane resin may be the above polyurethane resin. This coated granular fertilizer can be produced by a method comprising the steps of (a) applying an aromatic polyisocyanate, a polyol component (i.e., castor oil or a castor oil derivative), an amine, and the aqueous-fluid-absorbing particles, at the same time or separately in no special order, while the fertilizer granules are kept fluidized or rolled, thereby to form a precursory film on the fertilizer granules; and (b) curing the precursory film into the film. Each coated granular fertilizer is substantially superior in regulation of the release of plant nutrient elements therefrom.
摘要翻译：本发明涉及具有覆盖肥料颗粒的薄膜的涂覆颗粒肥料。该膜包括通过包括以下步骤的方法制备的聚氨酯树脂：（a）使芳族多异氰酸酯与第一多元醇组分（即蓖麻油或蓖麻油衍生物）反应，由此得到分子中具有末端异氰酸酯基团的预聚物 ; 和（b）使预聚物与第二多元醇组分（即蓖麻油或蓖麻油衍生物）和第三多元醇组分反应，所述第三多元醇组分是分子中具有至少两个羟基的胺，从而固化预聚物，从而使制备聚氨酯树脂。本发明涉及具有覆盖肥料颗粒的膜的另一种涂覆颗粒肥料。该膜包含聚氨酯树脂和粒径为1〜200μm的水溶液吸收性粒子。该聚氨酯树脂可以是上述聚氨酯树脂。该涂覆的颗粒肥料可以通过以下方法制备：（a）将芳族多异氰酸酯，多元醇组分（即蓖麻油或蓖麻油衍生物），胺和水性流体吸收颗粒施用于同时或以特殊顺序分开，同时将肥料颗粒保持流化或滚动，从而在肥料颗粒上形成前体膜; 和（b）将前体膜固化成膜。每个涂覆的颗粒肥料在调节植物营养元素的释放方面基本上都是优异的。

4. 发明授权

US6013695A Foundry binders containing modified polyisocyanates 有权
标题翻译：含有改性多异氰酸酯的铸造粘合剂
公开(公告)号：US6013695A
公开(公告)日：2000-01-11
申请号：US163589
申请日：1998-09-30
申请人： Michael Jeffrey Skoglund , Jeffery Dale Ungerer
发明人： Michael Jeffrey Skoglund , Jeffery Dale Ungerer
IPC分类号： B22C1/22 , C08G18/54 , C08G18/80
CPC分类号： C08G18/8051 , B22C1/2273 , C08G18/542
摘要： The invention relates to foundry binder systems which contain modified polyisocyanates. The modified polyisocyanates are prepared by reacting a polyisocyanate with a triglyceride of ricinoleic acid. These modified polyisocyanates a phenolic resole resin are mixed with a foundry aggregate to form a foundry mix which is shaped and cured with an amine curing catalyst.
摘要翻译：本发明涉及含有改性多异氰酸酯的铸造粘合剂体系。改性的多异氰酸酯是通过使多异氰酸酯与蓖麻酸的甘油三酯反应来制备的。将酚醛树脂树脂的这些改性多异氰酸酯与铸造骨料混合以形成用胺固化催化剂成形和固化的铸造混合物。

5. 发明授权

US5019317A Process for the production of molded products using internal mold release agents 失效
标题翻译：使用内部脱模剂生产成型产品的方法
公开(公告)号：US5019317A
公开(公告)日：1991-05-28
申请号：US356958
申请日：1989-05-24
申请人： Gregory H. Slocum , Donald W. Schumacher
发明人： Gregory H. Slocum , Donald W. Schumacher
IPC分类号： C08J5/00 , C08G18/08 , C08G18/10 , C08G18/28 , C08G18/42 , C08G18/50 , C08G18/80 , C08K5/098 , C08L75/00
CPC分类号： C08G18/10 , C08G18/281 , C08G18/4288 , C08G18/5021 , C08G18/8051 , C08G18/8061 , C08K5/098 , C08G2125/00
摘要： A process for producing a molded product by reacting an organic isocyanate component with an isocyanate reactive component. If the isocyanate component is based on a prepolymer of an isocyanate and a fatty acid ester, then the isocyanate reactive component must contain a fatty acid. Alternatively, if the isocyanate component contains a fatty acid, then the isocyanate reactive component must contain a zinc carboxylate. The system will release from bare steel.

6. 发明授权

US4598136A Embedding material and process for the production thereof 失效
标题翻译：嵌入材料及其生产工艺
公开(公告)号：US4598136A
公开(公告)日：1986-07-01
申请号：US716231
申请日：1985-03-26
申请人： Gerhard Wick
发明人： Gerhard Wick
IPC分类号： A61M1/16 , B01D63/02 , C08G18/10 , C08G18/22 , C08G18/32 , C08G18/36 , C08G18/80 , C08G18/83 , B01D13/00
CPC分类号： B01D63/023 , C08G18/22 , C08G18/32 , C08G18/36 , C08G18/8051
摘要： Aliphatic embedding masses are disclosed, prepared by initially reacting one or more aliphatic diisocyanates with castor oil or a mixture of castor oil and further hydroxyl compounds, such as e.g., trimethylol propane into a NCO-group-displaying pre-adduct, and the pre-adduct is then hardened in a catalyzed reaction with a mixture containing castor oil, trimethylol propane and N-methyldiethanol amine. Preferably iron acetyl acetonate, dibutyl tin diacetate or titanium tetrabutylate are employed as catalysts. Isophoron diisocyanate is particularly suitable as diisocyanate.The embedding masses are useful for the embedding of membranes, preferably membranes to be employed in medical fields. The embedding masses are bio-compatible, especially with regard to blood, and are non-toxic. They allow for the embedding of membranes with the aid of automatic machinery. The embedding masses display no or only negligible swelling when used in contact with blood, blood-like and aqueous systems.
摘要翻译：公开了通过使一种或多种脂族二异氰酸酯与蓖麻油或蓖麻油和其它羟基化合物如三羟甲基丙烷的混合物反应成NCO-组显示的预加合物的方法制备的脂肪族包埋块，加合物在与含有蓖麻油，三羟甲基丙烷和N-甲基二乙醇胺的混合物的催化反应中硬化。优选使用乙酰丙酮铁，二乙酸二丁基锡或四丁基钛作为催化剂。异佛尔酮二异氰酸酯特别适合作为二异氰酸酯。嵌入质量对于膜的嵌入是有用的，优选用于医疗领域的膜。嵌入质量是生物相容的，特别是在血液方面，是无毒的。它们允许借助自动机械嵌入膜。当与血液，血液和含水系统接触时，嵌入质量不显示或仅显示可忽略的肿胀。

7. 发明授权

US4267044A Thixotropic polyurethane compositions as sealants for membrane separatory devices 失效
标题翻译：触变性聚氨酯组合物作为膜分离装置的密封剂
公开(公告)号：US4267044A
公开(公告)日：1981-05-12
申请号：US894845
申请日：1978-04-10
申请人： Thaddeus F. Kroplinski , Barton C. Case
发明人： Thaddeus F. Kroplinski , Barton C. Case
IPC分类号： B01D63/14 , C08G18/10 , C08G18/12 , C08G18/80 , C08J3/24 , C08L75/04 , C09K3/10 , B01D31/00
CPC分类号： B01D63/023 , C08G18/10 , C08G18/12 , C08G18/8051
摘要： Novel thixotropic polyurethane compositions particularly useful as sealants for the edges of folded membrane separatory devices are provided which comprise;(a) a prepolymer comprising the reaction product of a polyol having a hydroxyl functionality of at least 2 with one mole per hydroxy group of said polyol of an organic diisocyanate; and(b) a crosslinking agent comprising a polyether polyol having a hydroxyl functionality of at least 2 and a primary amine-terminated polyether having an amine functionality of at least 2.To accelerate curing of the composition, the crosslinking agent can be modified by employing primary hydroxyl-terminated polyethers and/or adding hydroxyl-containing tertiary amines.
摘要翻译：提供特别用作折叠膜分离装置边缘的密封剂的新型触变性聚氨酯组合物，其包含：（a）包含羟基官能度至少为2的多元醇与有机二异氰酸酯的所述多元醇的每个羟基的摩尔数为1摩尔的反应产物的预聚物; 和（b）包含羟基官能度至少为2的聚醚多元醇和胺官能度至少为2的伯胺封端的聚醚的交联剂。为了加速组合物的固化，交联剂可以通过使用伯羟基封端的聚醚和/或加入含羟基的叔胺。

8. 发明授权

US4224201A Foundry binders 失效
标题翻译：铸造粘合剂
公开(公告)号：US4224201A
公开(公告)日：1980-09-23
申请号：US971128
申请日：1978-12-19
申请人： David Dumolo
发明人： David Dumolo
IPC分类号： B22C1/22 , C08G18/32 , C08G18/66 , C08G18/80 , B22C1/24 , C08L91/00
CPC分类号： C08G18/3215 , B22C1/2273 , C08G18/6674 , C08G18/8051
摘要： In a foundry binder comprising a polyisocyanate and a polyhydroxy composition, the polyisocyanate is modified by reaction with a drying oil. The composition is useful in a "cold box" process.
摘要翻译：在包含多异氰酸酯和多羟基组合物的铸造粘合剂中，多异氰酸酯通过与干燥油反应来改性。该组合物可用于“冷箱”过程。

9. 发明授权

US3645942A Foundry process using a propoxylated toluene diamine as an extender with a castor oil-aromatic diisocyanate prepolymer 失效
标题翻译：使用丙氧基硅烷二胺作为延长剂与蓖麻油芳族二异氰酸酯预聚物的方法
公开(公告)号：US3645942A
公开(公告)日：1972-02-29
申请号：US3645942D
申请日：1970-04-29
申请人： QUAKER OATS CO
发明人： BROWN LLOYD H , KLEMM LAURENCE J
IPC分类号： B22C1/22 , B22C1/24 , C08G18/36 , C08G18/50 , C08G18/80 , C08G22/04
CPC分类号： C08G18/36 , B22C1/2273 , B22C1/24 , C08G18/5033 , C08G18/8051
摘要： A FOUNDRY PROCESS IS DISCLOSED INCLUDING THE USE OF NOVEL CORE BINDERS WHICH ARE PREPARED BY FIRST FORMING A PREPOLYMER FROM AN AROMATIC POLYISOCYANATE AND NONDRYING CASTOR OIL; THEN MIXING THE PREPOLYMER WITH A HIGH MOLECULAR WEIGHT HYDROXY CONTAINING MATERIAL AND AN ACCELERATOR. THE HIGH MOLECULAR WEIGHT HYDROXY CONTAINING MATERIAL CAN BE EITHER AN ALIPHATIC POLYETHER POLYOL OR AN AROMATIC POLYETHER POLYOL. THE ACCELERATOR CAN BE EITHER A METAL NAPHTHENATE, ORGANOTIN COMPOUND, OR TERTIARY AMINE. THE PREPOLYMER MAY ALSO INCLUDE TUNG OIL.

10. 发明授权

US3362921A Novel elastomeric products obtained from prepolymer compositions 失效
标题翻译：从预聚物组合物获得的新型弹性体产品
公开(公告)号：US3362921A
公开(公告)日：1968-01-09
申请号：US44671965
申请日：1965-04-08
申请人： BAKER CASTOR OIL CO
发明人： ARTHUR EHRLICH , PATTON TEMPLE C , KENT SMITH MALCOLM
IPC分类号： C08G18/10 , C08G18/36 , C08G18/80
CPC分类号： C08G18/8051 , C08G18/10 , C08G18/36

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