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1. 发明申请

US20170036923A1 Acoustic Pressure Shock Wave Devices and Methods for Fluids Processing 审中-公开
标题翻译：声压冲击波器件和流体处理方法
公开(公告)号：US20170036923A1
公开(公告)日：2017-02-09
申请号：US15230765
申请日：2016-08-08
申请人： SANUWAVE, INC.
发明人： IULIAN CIOANTA , JOHN JACKSON
IPC分类号： C02F1/36 , B01D21/28 , B01D21/00 , C02F1/24
CPC分类号： C02F1/36 , B01D9/0004 , B01D9/0009 , B01D9/0036 , B01D9/0081 , B01D21/0006 , B01D21/0012 , B01D21/0084 , B01D21/009 , B01D21/283 , B01D61/025 , B01D65/02 , B01D65/08 , B01D2313/20 , B01D2313/24 , B01D2313/36 , B01D2321/2066 , B01D2321/30 , B03D3/04 , C01B5/00 , C02F1/22 , C02F1/44 , C02F1/441 , C02F1/52 , C02F11/12 , C02F2001/5218 , C02F2101/32 , C02F2103/08 , C02F2201/008 , C02F2303/04 , C02F2303/16 , C02F2303/20 , C02F2303/22 , G21F9/06 , G21Y2002/60 , G21Y2004/20 , Y02A20/131 , Y02A20/132 , Y02W10/30 , Y02W10/37
摘要： A method of treating fluids, including for recovery of water apart from impurities or undesired matter, utilizes application of shock waves to the fluids.
摘要翻译：处理流体的方法，包括除了杂质或不需要的物质之外的回收水，利用冲击波对流体施加。

2. 发明申请

US20160030859A1 APPARATUS FOR MANUFACTURING SALT 审中-公开
标题翻译：制造盐的装置
公开(公告)号：US20160030859A1
公开(公告)日：2016-02-04
申请号：US14775022
申请日：2013-07-26
申请人： Jin Ho KIM
发明人： Jin Ho KIM
IPC分类号： B01D9/00 , B01D1/18 , A23L1/237 , C01D3/06
CPC分类号： B01D9/0027 , A23L27/40 , A23V2002/00 , B01D1/18 , B01D9/0031 , B01D9/005 , B01D9/0081 , B01D2009/0086 , C01D3/06 , C02F1/04
摘要： The present invention relates to an apparatus for manufacturing salt, and more particularly to an apparatus for manufacturing salt, which is capable of obtaining mineral salt containing a high concentration of minerals, manufacturing salt at relatively low cost in a relatively small space, and exhibiting maximum efficiency of drying or evaporation since seawater is heated and sprayed onto a cloth or net.
摘要翻译：本发明涉及一种盐的制造装置，更具体地涉及一种盐的制造装置，其能够获得含有高浓度矿物质的矿物盐，在相对小的空间中以相对较低的成本制造盐，并且显示最大值干燥或蒸发的效率，因为海水被加热并喷洒到布或网上。

3. 发明申请

US20160001252A1 Process for Making Crystals 审中-公开
标题翻译：制作晶体的过程
公开(公告)号：US20160001252A1
公开(公告)日：2016-01-07
申请号：US14854750
申请日：2015-09-15
申请人： James Robinson , Graham Ruecroft
发明人： James Robinson , Graham Ruecroft
IPC分类号： B01J19/10 , C07J31/00
CPC分类号： B01J19/10 , B01D9/0054 , B01D9/0081 , B01J2/02 , B01J2/18 , B01J19/18 , B01J2219/0011 , B01J2219/00114 , C07J31/006
摘要： A process for preparing crystalline particles of an active principal in the presence of ultrasonic irradiation that comprises contacting a solution of a solute in a solvent in a first flowing stream with an anti-solvent in a second flowing stream causing the mixing thereof, wherein the flow rate ratio of the anti-solvent: solvent is higher than 20:1, and collecting crystals that are generated.
摘要翻译：一种在超声波照射的存在下制备活性物质的结晶颗粒的方法，该方法包括使第一流动中的溶剂中的溶质与抗溶剂在第二流动流中接触，引起其混合，其中流动反溶剂：溶剂的速率比高于20:1，收集产生的结晶。

4. 发明授权

US08992981B2 Method for producing microparticles and the microparticles 有权
标题翻译：微粒和微粒的制造方法
公开(公告)号：US08992981B2
公开(公告)日：2015-03-31
申请号：US12679172
申请日：2008-09-11
申请人： Masakazu Enomura
发明人： Masakazu Enomura
IPC分类号： A61K9/14 , B01D9/00 , A61K9/50 , B01J19/10 , B01J19/12 , B01J19/18
CPC分类号： B01D9/0013 , A61K9/146 , A61K9/5089 , B01D9/0031 , B01D9/0081 , B01J19/10 , B01J19/123 , B01J19/1887 , B01J2219/00094 , B01J2219/00137 , Y10T428/2982
摘要： It is an object of the present invention to provide a method for producing microparticles, which can produce monodispersed microparticles, causes no clogging with a product due to self-dischargeability, requires no great pressure, and is excellent in productivity, wherein a fluid in which at least one kind of microparticle materials is dissolved is introduced between two processing surfaces arranged to be opposite to each other to be able to approach to and separate from each other, at least one of which rotates relative to the other, to be formed into a thin film fluid, and the thin film fluid is cooled or heated (warmed) to allow saturation solubility to change, thereby separating microparticles.
摘要翻译：本发明的目的是提供一种能够生产单分散微粒的微粒的制造方法，不会由于自放电性而导致产品不堵塞，不需要大的压力，生产率优异，其中，将至少一种微粒材料溶解在彼此相对布置的两个处理表面之间，以能够彼此接近和分离，其中至少一个相对于另一个旋转，形成为薄膜流体，并且薄膜流体被冷却或加热（加热）以允许饱和溶解度改变，从而分离微粒。

5. 发明申请

US20110288060A1 APPARATUS AND PROCESS FOR PRODUCING CRYSTALS 审中-公开
标题翻译：用于生产水晶的装置和方法
公开(公告)号：US20110288060A1
公开(公告)日：2011-11-24
申请号：US13143257
申请日：2010-01-05
申请人： Graham Ruecroft , John Burns
发明人： Graham Ruecroft , John Burns
IPC分类号： A61K31/58 , A61K31/19 , A61K31/135 , A61P37/08 , A61P11/08 , A61P29/00 , A61P31/12 , A61P31/00 , A61P35/00 , A61P25/00 , A61P9/00 , A61P25/16 , A61P31/18 , A61P25/08 , A61P1/00 , A61P21/00 , A61P3/00 , A61P13/00 , A61P19/00 , B01J8/16 , B01J19/10 , A61K31/56
CPC分类号： B01J19/10 , B01D9/005 , B01D9/0054 , B01D9/0059 , B01D9/0081 , B01J19/006 , B01J19/1812 , B01J19/185 , B01J2219/00094 , B01J2219/00166 , B01J2219/00175 , B01J2219/00186 , Y10T428/2982
摘要： This invention provides an oscillating baffled reactor apparatus for preparing crystalline particles of at least one substance comprising: a reactor vessel; means for supplying a first flowing stream; means for oscillating fluid within the reactor vessel; a plurality of baffles; source of ultrasonic radiation; and means for collecting said particles.
摘要翻译：本发明提供一种用于制备至少一种物质的结晶颗粒的摆动挡板反应器装置，包括：反应器容器; 用于提供第一流动流的装置; 用于在反应堆容器内振荡流体的装置; 多个挡板; 超声波辐射源; 以及用于收集所述颗粒的装置。

6. 发明申请

US20090068275A1 Process for the Manufacture of Powders of Inhalable Medicaments 有权
标题翻译：可吸入药物粉末制造工艺
公开(公告)号：US20090068275A1
公开(公告)日：2009-03-12
申请号：US12263818
申请日：2008-11-03
申请人： Nathalie JONGEN , Jacques LEMAITRE , Paul BOWEN , Marcel DONNET , Joerg SCHIEWE , Bernd ZIERENBERG
发明人： Nathalie JONGEN , Jacques LEMAITRE , Paul BOWEN , Marcel DONNET , Joerg SCHIEWE , Bernd ZIERENBERG
IPC分类号： A61K9/14 , B01J19/10
CPC分类号： B01F13/0071 , A61K9/0075 , A61K9/1688 , B01D9/0013 , B01D9/005 , B01D9/0054 , B01D9/0081 , B01F2215/0431 , B01J2/18 , B01J19/0093 , B01J2219/00788 , B01J2219/0086 , B01J2219/00873 , B01J2219/00889 , B01J2219/00932 , B01J2219/00984
摘要： The invention relates to an improved process for the production of powders of an inhalable medicament by crystallization from a supersaturated fluid containing said medicament, the method comprising passing along a tubular reactor (a) a segmented flow of that fluid comprised of discrete volumes; or (b) a fluid mixture being separated by discrete volumes of a separating fluid which is substantially immiscible with said fluid, characterized in that the crystallization is initiated by application of ultrasound
摘要翻译：本发明涉及通过从含有所述药物的过饱和流体结晶生产可吸入药物的粉末的改进方法，所述方法包括沿着管状反应器（a）将由该离散体构成的流体的分段流动; 或（b）流体混合物被离散体积分离的液体分离，分离流体与所述流体基本上不混溶，其特征在于，通过施加超声波

7. 发明授权

US07244307B2 Production of crystalline materials by using high intensity ultrasound 有权
标题翻译：通过使用高强度超声波生产结晶材料
公开(公告)号：US07244307B2
公开(公告)日：2007-07-17
申请号：US10513154
申请日：2003-05-08
申请人： Linda Jane McCausland
发明人： Linda Jane McCausland
IPC分类号： C30B15/01
CPC分类号： B01D9/0013 , B01D9/005 , B01D9/0054 , B01D9/0081
摘要： A crystalline material sufficiently pure for use in pharmaceuticals may be made by forming a saturated solution of the material changing the temperature of the solution so it becomes supersaturated, and briefly subjecting the solution to irradiation by high intensity ultrasound, before allowing the solution to cool gradually without further irradiation. The ultrasound may be applied using a vessel with an array of ultrasonic transducers attached to a wall, so each transducer radiates no more than 3 W/cm2 yet the power dissipation within the vessel is between 25 and 150 W/litre. This method can reduce the metastable zone width to less than 10 K. There is no erosion of the wall and consequently no formation of small particles of metal. It is applicable for example to aspartame, and to amino acids.
摘要翻译：用于药物的足够纯的结晶物质可以通过形成改变溶液温度的材料的饱和溶液使其变得过饱和，并且在使溶液逐渐冷却之前将溶液短暂地经过高强度超声波照射，无需进一步照射。可以使用具有附接到壁的超声波换能器阵列的血管来应用超声波，因此每个换能器辐射不超过3W / cm 2，而容器内的功率耗散在25和150之间 W /升。这种方法可以将亚稳区宽度减小到小于10K。没有壁的侵蚀，因此没有形成小的金属颗粒。它适用于例如阿斯巴甜和氨基酸。

8. 发明申请

US20050163683A1 Production of crystalline materials by using high intensity ultrasound 有权
标题翻译：通过使用高强度超声波生产结晶材料
公开(公告)号：US20050163683A1
公开(公告)日：2005-07-28
申请号：US10513154
申请日：2003-05-08
申请人： Linda McCausland
发明人： Linda McCausland
IPC分类号： B01D9/00
CPC分类号： B01D9/0013 , B01D9/005 , B01D9/0054 , B01D9/0081
摘要： A crystalline material sufficiently pure for use in pharmaceuticals may be made by forming a saturated solution of the material changing the temperature of the solution so it becomes supersaturated, and briefly subjecting the solution to irradiation by high intensity ultrasound, before allowing the solution to cool gradually without further irradiation. The ultrasound may be applied using a vessel with an array of ultrasonic transducers attached to a wall, so each transducer radiates no more than 3 W/cm2 yet the power dissipation within the vessel is between 25 and 150 W/litre. This method can reduce the metastable zone width to less than 10 K. There is no erosion of the wall and consequently no formation of small particles of metal. It is applicable for example to aspartame, and to amino acids.
摘要翻译：用于药物的足够纯的结晶物质可以通过形成改变溶液温度的材料的饱和溶液使其变得过饱和，并且在使溶液逐渐冷却之前将溶液短暂地经过高强度超声波照射，无需进一步照射。可以使用具有附接到壁的超声波换能器阵列的血管来应用超声波，因此每个换能器辐射不超过3W / cm 2，而容器内的功率耗散在25和150之间 W /升。这种方法可以将亚稳区宽度减小到小于10K。没有壁的侵蚀，因此没有形成小的金属颗粒。它适用于例如阿斯巴甜和氨基酸。

9. 发明授权

US06808638B1 Methods and apparatus for processing temperature sensitive materials 失效
标题翻译：温度敏感材料的处理方法和设备
公开(公告)号：US06808638B1
公开(公告)日：2004-10-26
申请号：US09805770
申请日：2001-06-25
申请人： Howard E. Purdum
发明人： Howard E. Purdum
IPC分类号： B01D900
CPC分类号： B01D9/005 , B01D7/00 , B01D9/0036 , B01D9/0059 , B01D9/0081 , B01D15/3866 , B01D17/042 , B01D17/048 , B01D21/26 , B01D61/243
摘要： A method and system (10) for selectively removing one component of a material thereby concentrating other components of the material are disclosed. The material is cooled to below the melting temperature of the material to form a supercooled liquid phase with heat transfer plate with cooling channels (20). Ultrasonic energy from ultrasonic drivers (42) is applied to the material to form solid phase crystals of the component to be removed. These crystals are removed to leave the concentrated products. The ultrasonic energy prevents the growth of dendrites on the crystals, resulting in the formation and removal of small crystals of the component to be removed without damage to or removal of the remaining components. Methods and apparatuses for cryoprecipilation and chromatography are also disclosed.
摘要翻译：公开了一种用于选择性地去除材料的一个部件从而集中材料的其它部件的方法和系统（10）。将材料冷却至材料的熔融温度以形成具有带有冷却通道（20）的传热板的过冷液相。将来自超声波驱动器（42）的超声波能量施加到该材料上以形成待除去部件的固相晶体。去除这些晶体以留下浓缩的产物。超声波能量可防止晶体上的枝晶生长，导致要除去的组分的小晶体的形成和去除，而不损坏或除去其余组分。还公开了用于冷沉淀和色谱法的方法和装置。

10. 发明申请

US20040197275A1 Process for the manufacture of powders of inhalable medicaments 审中-公开
标题翻译：制造可吸入药物粉末的方法
公开(公告)号：US20040197275A1
公开(公告)日：2004-10-07
申请号：US10685254
申请日：2003-10-14
申请人： ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE , Boehringer Ingelheim Pharma GmbH & Co., KG
发明人： Nathalie Jongen , Jacques Lemaitre , Paul Bowen , Marcel Donnet , Joerg Schiewe , Bernd Zierenberg , Cristina Lucica Soare
IPC分类号： A61L009/04 , A61K009/14
CPC分类号： B01F13/0071 , A61K9/0075 , A61K9/1688 , B01D9/0013 , B01D9/005 , B01D9/0054 , B01D9/0081 , B01F2215/0431 , B01J2/18 , B01J19/0093 , B01J2219/00788 , B01J2219/0086 , B01J2219/00873 , B01J2219/00889 , B01J2219/00932 , B01J2219/00984
摘要： The invention relates to an improved process for the production of powders of an inhalable medicament by crystallization from a supersaturated fluid containing said medicament, the method comprising passing along a tubular reactor (a) a segmented flow of that fluid comprised of discrete volumes; or (b) a fluid mixture being separated by discrete volumes of a separating fluid which is substantially immiscible with said fluid, characterized in that the crystallization is initiated by application of ultrasound
摘要翻译：本发明涉及通过从含有所述药物的过饱和流体结晶生产可吸入药物的粉末的改进方法，所述方法包括沿着管状反应器（a）将由该离散体构成的流体的分段流动; 或（b）流体混合物被离散体积分离的液体分离，分离流体与所述流体基本上不混溶，其特征在于，通过施加超声波

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