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    • 2. 发明申请
    • Brain Portal
    • 脑门
    • US20170000996A1
    • 2017-01-05
    • US14341271
    • 2014-07-25
    • alan edward odonnell
    • alan edward odonnell
    • A61M39/02A61N1/05
    • A61M39/0247A61M2039/025A61M2039/0267A61M2039/0276A61M2207/00A61M2210/0687A61M2210/0693A61N1/0529
    • The Brain Portal is a device that allows for easy access to the brain for treatments that require multiple visits inside the brain case to alleviate the need for multiple craniotomies. Such treatments could involve multiple injections of medicines that have to be given over a period of days or weeks. In a different configuration, it also allows for electrical stimulation of the brain thru electrodes without the need for batteries, and allows the flow of electricity from outside the brain to the affected areas using induction coils. The Brain Portal can also be used as an easy means to collect samples of cerebral spinal fluid without the need of a spinal tap. Furthermore, having an easy access allows the physician the option of injecting drugs directly into the brain, bypassing the blood-brain barrier, thereby lowering the dosage needed to treat disease.
    • 脑门是一种允许容易进入脑部进行治疗的设备,需要在脑外部进行多次访问,以减轻多次开颅手术的需要。 这种治疗可能涉及多次注射药物,必须在几天或几周的时间内给药。 在不同的配置中,它还允许通过电极对脑的电刺激而不需要电池,并且允许使用感应线圈从大脑外部向受影响的区域流动电力。 大脑门户也可以作为收集脑脊髓液样本的简单手段,无需脊柱抽头。 此外,容易进入允许医生选择将药物直接注射到脑中,绕过血脑屏障,从而降低治疗疾病所需的剂量。
    • 6. 发明授权
    • Neural stimulator with percutaneous connectivity
    • 具有经皮连接的神经刺激器
    • US08655455B2
    • 2014-02-18
    • US13500731
    • 2010-09-30
    • Alfred E. MannTom Xiaohai He
    • Alfred E. MannTom Xiaohai He
    • A61N1/00
    • A61N1/0539A61M39/0247A61M2039/0261A61M2039/0267A61N1/0536A61N1/36017A61N1/36128
    • An implantable neurostimulation system includes both implantable and external components. Electrical connectivity between the external and implanted components is achieved through a plurality of feedthrough pins located within an insulative wall of a percutaneous port embedded in the skin. The percutaneous port has the general shape and appearance of a small thimble, embedded in the skin with its open end facing outwardly from the skin surface, and with its closed end located below the skin surface, thereby forming a cavity or dimple in the skin. Various plugs or cartridges can be removably inserted into the cavity of the percutaneous port, in various orientations, to facilitate appropriate connectivity between the external and implanted components of the system through selected ones of the feedthrough pins. A mesh edging secured around the periphery wall of the port promotes tissue ingrowth and vascularization, thereby forming a percutaneous seal around the port that prevents infection.
    • 植入式神经刺激系统包括可植入和外部组件。 外部和植入部件之间的电连接通过位于皮肤内的经皮端口的绝缘壁内的多个穿通针来实现。 经皮端口具有嵌入皮肤中的小套管的一般形状和外观,其开口端从皮肤表面向外,并且其封闭端位于皮肤表面下方,从而在皮肤中形成空腔或凹坑。 可以以各种取向将各种插头或药筒可移除地插入到经皮端口的空腔中,以通过选定的馈通针来促进系统的外部部件和植入部件之间的适当连接。 围绕端口的周围壁固定的网状边缘促进组织向内生长和血管形成,从而在端口周围形成防止感染的经皮密封。
    • 9. 发明授权
    • Method for measuring blood pressure in an animal or human using a
percutaneous access port
    • 使用经皮进入口测量动物或人体血压的方法
    • US5120313A
    • 1992-06-09
    • US749755
    • 1990-03-20
    • Nancy W. Elftman
    • Nancy W. Elftman
    • A61M1/00A61M39/02
    • A61M39/0247A61M39/0208A61M2039/0267A61M2039/0282
    • A percutaneous access port for providing access to a selected organ in an animal which includes a base assembly and a septum assembly. The base assembly has a fluid chamber formed in a portion thereof generally between an upper and a lower end of the base assembly with an inlet port being formed in a portion in the base assembly gnerally near the lower end of the base assembly. The inlet port is adapted to be connected to the selected organ to provide communication between the fluid chamber in the base assembly and the selected organ. At least one access port is formed through the upper end of the base assembly with each access port extending a distance through the base assembly and intersecting the fluid chamber to provide communication between the upper end of the base assembly and the fluid chamber. The septum assembly includes a portion which extends across each access port in the base assembly to resealably seal each access port, each access port providing resealable access to the fluid chamber. A transducer is disposed in the fluid chamber of the base assembly and the transducer is adapted to detect the pressure of the fluid within the fluid chamber and to provide an output transducer signal indicative of the pressure of the fluid in the fluid chamber, the transducer providing output signal continuously providing an output indication of fluid pressure in an implanted condition of the base assembly with the transducer connected thereto.
    • 用于提供对包括基部组件和隔膜组件的动物中的选定器官的通路的经皮进入口。 基座组件具有大致在基部组件的上端和下端之间形成的流体室,其中入口端口形成在底座组件中靠近基座组件下端的部分中。 入口端口适于连接到所选择的器官,以提供基座组件中的流体室与所选择的器官之间的连通。 至少一个进入口通过基座组件的上端形成,每个进入口延伸穿过基座组件一定距离,并与流体室相交,以提供基座组件的上端与流体室之间的连通。 隔膜组件包括延伸穿过基座组件中的每个进入口的部分,以可再密封地密封每个进入端口,每个进入口提供对流体室的可重新密封的通路。 换能器设置在基座组件的流体室中,并且换能器适于检测流体室内的流体的压力,并提供指示流体室中流体的压力的输出换能器信号,换能器提供 输出信号连续地提供基座组件的植入状态下的流体压力的输出指示,其中换能器连接到基座组件。