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1. 发明授权

US12004954B2 Method for performing single-stage cranioplasty reconstruction with a clear custom craniofacial implant 有权
公开(公告)号：US12004954B2
公开(公告)日：2024-06-11
申请号：US17654879
申请日：2022-03-15
申请人： Longeviti Neuro Solutions LLC
发明人： Chad R. Gordon , Jesse Christopher , Bradley Rabinovitz
IPC分类号： A61F2/28 , A61B17/68 , A61B17/80 , A61F2/30 , A61B17/00 , A61B34/10 , A61B90/10
CPC分类号： A61F2/2875 , A61B17/688 , A61B17/8061 , A61F2/30942 , A61B2017/00907 , A61B2017/00924 , A61B2017/00955 , A61B2034/105 , A61B2034/108 , A61B2090/103 , A61F2002/2882 , A61F2002/3009 , A61F2002/30948 , A61F2002/3096
摘要： A method for performing a cranioplasty includes the steps of prefabricating a sonolucent craniofacial implant based upon information generated by preoperative scans, creating a cranial, craniofacial, and/or facial defect, and attaching the craniofacial implant to the cranial, craniofacial, and/or facial defect. The craniofacial implant is composed of a material that is sonolucent and exhibits attenuation of less than 6 dB/cm.

2. 发明申请

US20170296309A1 Bioresorbable Inflatable Devices, Incision Tool And Methods For Tissue Expansion And Tissue Regeneration 审中-公开
公开(公告)号：US20170296309A1
公开(公告)日：2017-10-19
申请号：US15590479
申请日：2017-05-09
申请人： BEN ZION KARMON
发明人： BEN ZION KARMON
IPC分类号： A61C8/00 , A61F2/28 , A61F2/46 , A61C8/02 , A61F2/30
CPC分类号： A61C8/0092 , A61B17/1673 , A61B17/1688 , A61B17/666 , A61B17/7097 , A61B2017/00557 , A61C8/0006 , A61C8/004 , A61F2/2803 , A61F2/2875 , A61F2/4601 , A61F2/82 , A61F2002/2807 , A61F2002/2817 , A61F2002/2835 , A61F2002/2882 , A61F2002/2885 , A61F2002/2889 , A61F2002/30014 , A61F2002/30062 , A61F2002/30074 , A61F2002/30075 , A61F2002/30092 , A61F2002/30115 , A61F2002/3025 , A61F2002/30372 , A61F2002/3052 , A61F2002/30581 , A61F2002/30601 , A61F2002/30677 , A61F2002/30841 , A61F2002/30906 , A61F2002/30925 , A61F2002/4623 , A61F2210/0004 , A61F2210/0014 , A61F2210/0057 , A61F2210/0061 , A61F2220/0025 , A61F2220/0033 , A61F2250/0018 , A61F2250/0065 , A61F2250/0067 , A61F2310/00017 , A61F2310/00023 , A61F2310/00089 , A61F2310/00131 , A61F2310/00161 , A61F2310/00179 , A61F2310/00407 , A61F2310/00796 , Y10S623/908
摘要： Bioresorbable inflatable devices and tunnel incision tool and methods for treating and enlarging a tissue or an organ or a tube or a vessel or a cavity. The device is composed of a hollow expanding pouch made of a resorbable material that can be attached to a filling element. The pouch can be filled with a biocompatible materials, one or more times in few days interval, after the insertion of the device. While filling the pouch every few days the tissue expands and the filling material if it is bioactive start to function. The tunnel incision tool composed of a little blade that emerges from the surface of the tool in order to make shallow incisions in the surrounding tissue therefore enabling easy expansion of the tissue. This device and method can be used for example for: horizontal and vertical bone augmentation in the jaws and the tunnel incision tool is used to make shallow incisions in the periosteum when using the tunnel technique, sinus augmentation when the device is placed beneath the Schneiderian tissue, vessels widening if the pouch become a stent etc.

3. 发明授权

US09789225B2 Shapeable bone graft substitute and instruments for delivery thereof 有权
公开(公告)号：US09789225B2
公开(公告)日：2017-10-17
申请号：US14933217
申请日：2015-11-05
申请人： Orthovita, Inc.
发明人： Charanpreet S. Bagga , Theodore D. Clineff , Erik M. Erbe , Michael W. Paris , Gina M. Nagvajara , Antony Koblish
IPC分类号： A61F2/00 , A61L27/54 , A61B17/68 , A61B17/70 , A61B17/88 , A61F2/28 , A61L27/46 , A61L27/50 , A61L27/56 , A61L27/58 , A61L27/20 , A61F2/30 , A61F2/34 , A61F2/38 , A61F2/46
CPC分类号： A61L27/54 , A61B17/68 , A61B17/7095 , A61B17/8822 , A61F2/28 , A61F2/2803 , A61F2/2875 , A61F2/3094 , A61F2/34 , A61F2/389 , A61F2/4601 , A61F2/4644 , A61F2002/2817 , A61F2002/2835 , A61F2002/2882 , A61F2002/30062 , A61F2002/30151 , A61F2002/30224 , A61F2002/30235 , A61F2002/30247 , A61F2002/30261 , A61F2002/30622 , A61F2002/30677 , A61F2002/30736 , A61F2002/30838 , A61F2210/0004 , A61F2210/0085 , A61F2230/0017 , A61F2230/0069 , A61F2230/0071 , A61F2230/0082 , A61F2310/00293 , A61F2310/00365 , A61L27/20 , A61L27/46 , A61L27/50 , A61L27/56 , A61L27/58 , A61L2400/06 , A61L2400/16 , A61L2430/02 , C08L89/06
摘要： Injectable bone graft material having a biocompatible, resorbable polymer and a biocompatible, resorbable inorganic material exhibiting macro, meso, and microporosities.

4. 发明申请

US20150209147A1 Malar Implant with Dual-Plane Adhesion 审中-公开
标题翻译：具有双平面粘附力的Mal牙种植体
公开(公告)号：US20150209147A1
公开(公告)日：2015-07-30
申请号：US14163184
申请日：2014-01-24
申请人： J. Randall Jordan , Benjamin Googe
发明人： J. Randall Jordan , Benjamin Googe
IPC分类号： A61F2/28
CPC分类号： A61F2/2875 , A61F2/0059 , A61F2002/2882
摘要： A malar implant for mid-face lifts and reconstructions is disclosed. The malar implant is designed to be attached to both bone and soft tissue, and provides both volume and soft tissue lift. A depending tab or lip on the superior edge of the implant attaches to the inferior orbital rim. The implant has a central plateau, which may be gently curved, that includes a number of soft tissue spikes. In one embodiment, the soft tissue spikes have the general shapes of bent isosceles triangular pyramids, thicker at the base than at the tip. The soft tissue spikes may be angled upwardly, toward the superior edge, to reposition and suspend the soft tissues of the mid-face.
摘要翻译：公开了一种用于中层升降机和重建的跖骨植入物。颌骨植入物被设计成连接到骨骼和软组织，并且提供体积和软组织提升。植入物上边缘上的悬垂突片或唇缘附着于下轨道边缘。植入物具有中央平台，其可以是柔和的弯曲的，其包括许多软组织尖峰。在一个实施例中，软组织钉具有弯曲的等腰三角锥体的一般形状，在基部处比在尖端处更厚。软组织尖峰可以向上朝向上边缘倾斜，以重新定位和悬挂中间面的软组织。

5. 发明申请

US20060217813A1 Facial implant 审中-公开
标题翻译：面部植入
公开(公告)号：US20060217813A1
公开(公告)日：2006-09-28
申请号：US11385688
申请日：2006-03-22
申请人： Jeffrey Posnick , Alma Coats
发明人： Jeffrey Posnick , Alma Coats
IPC分类号： A61F2/28 , B29C67/04
CPC分类号： A61F2/2875 , A61F2/141 , A61F2/30767 , A61F2/3094 , A61F2/30965 , A61F2002/183 , A61F2002/2807 , A61F2002/2878 , A61F2002/2882 , A61F2002/2885 , A61F2002/30065 , A61F2002/30324 , A61F2002/30616 , A61F2002/30736 , A61F2002/30948 , A61F2002/30952 , A61F2002/30957 , A61F2002/30968 , A61F2002/30991 , A61F2002/30993 , A61F2210/0071 , A61F2250/0036 , A61F2310/00401 , A61F2310/00407 , A61F2310/00928 , A61F2310/0097 , A61F2310/00976 , A61F2310/00982
摘要： A facial implant includes fused polypropylene pellets. The pellets can be molded to a contoured shape. The shape can be used to augment, replace, or repair cranio-maxillofacial areas, such as the malar, mandibular angle, paranasal, nasal, temporal, cranial vault, orbital, ocular globe, and chin areas of a mammal, such as a human.
摘要翻译：面部植入物包括熔融聚丙烯颗粒。颗粒可以模制成轮廓形状。该形状可以用于增加，替换或修复诸如人类的哺乳动物（例如人类）的颅颌面部区域，例如肛门，下颌角，鼻旁，鼻，颞，颅骨，眼眶，眼球和下颌区域。

6. 发明授权

US06863899B2 Composite shaped bodies and methods for their production and use 有权
标题翻译：复合成型体及其生产和使用方法
公开(公告)号：US06863899B2
公开(公告)日：2005-03-08
申请号：US10165629
申请日：2002-06-07
申请人： Antony Koblish , Ronald Sapieszko , David Dychala , Erik Erbe
发明人： Antony Koblish , Ronald Sapieszko , David Dychala , Erik Erbe
IPC分类号： A61L27/00 , A61B17/64 , A61B17/70 , A61B17/74 , A61B17/80 , A61B17/86 , A61C8/00 , A61F2/00 , A61F2/28 , A61F2/30 , A61F2/32 , A61F2/36 , A61F2/38 , A61F2/44 , A61K9/14 , A61L27/02 , A61L27/12 , A61L27/42 , A61L27/56 , A61F13/00 , A61K7/16
CPC分类号： A61F2/28 , A61B17/64 , A61B17/70 , A61B17/742 , A61B17/80 , A61B17/866 , A61C8/0012 , A61F2/2803 , A61F2/2875 , A61F2/3094 , A61F2/32 , A61F2/38 , A61F2/3872 , A61F2/3877 , A61F2/389 , A61F2/4455 , A61F2/446 , A61F2/4465 , A61F2/447 , A61F2002/2825 , A61F2002/2882 , A61F2002/30187 , A61F2002/3895 , A61F2002/448 , A61F2230/0034 , A61L27/02 , A61L27/12 , A61L27/425 , A61L27/56
摘要： Shaped, composite bodies are provided. One portion of the shaped bodies comprises an RPR-derived porous inorganic material, preferably a calcium phosphate. Another portion of the composite bodies is a different solid material, preferably metal, glass, ceramic or polymeric. The shaped bodies are especially suitable for orthopaedic and other surgical use.
摘要翻译：提供成形的复合材料。成形体的一部分包括RPR衍生的多孔无机材料，优选磷酸钙。复合体的另一部分是不同的固体材料，优选金属，玻璃，陶瓷或聚合物。成形体特别适用于骨科和其他外科用途。

7. 发明公开

US20240277478A1 CRANIOMAXILLOFACIAL IMPLANT AND METHOD OF DESIGNING THEREOF 审中-公开
公开(公告)号：US20240277478A1
公开(公告)日：2024-08-22
申请号：US18568491
申请日：2021-06-08
申请人： METICULY COMPANY LIMITED
发明人： Kanin Sirichatchai , Kantapat Phakdeewisetkul , Tanya Charoensrisomboon , Thanakorn Thiensri
IPC分类号： A61F2/28 , A61F2/30
CPC分类号： A61F2/2875 , A61F2/30942 , A61F2002/2878 , A61F2002/2882
摘要： A method of designing a craniomaxillofacial implant that is a rigid plate of substantially uniform thickness, including: positioning a surface element of the plate as a departure from a reference location within a base outline, the departure being represented by a fraction of the length of a normal path projected from the reference location to a predetermined soft tissue layer at a supported location within an anatomic region of interest, and the fraction being based upon a required patient-specific support at the supported location.

8. 发明授权

US12004953B2 Method for performing single-stage cranioplasty reconstruction with a clear custom craniofacial implant 有权
公开(公告)号：US12004953B2
公开(公告)日：2024-06-11
申请号：US17654872
申请日：2022-03-15
申请人： Longeviti Neuro Solutions LLC
发明人： Chad R. Gordon , Jesse Christopher , Bradley Rabinovitz
IPC分类号： A61F2/28 , A61B17/68 , A61B17/80 , A61F2/30 , A61B17/00 , A61B34/10
CPC分类号： A61F2/2875 , A61B17/688 , A61B17/8061 , A61F2/30942 , A61B2017/00907 , A61B2017/00924 , A61B2034/105 , A61B2034/108 , A61F2002/2882 , A61F2002/3009 , A61F2002/30948 , A61F2002/3096
摘要： A method for performing a cranioplasty includes the steps of prefabricating a sonolucent craniofacial implant based upon information generated by preoperative scans, creating a cranial, craniofacial, and/or facial defect, and attaching the craniofacial implant to the cranial, craniofacial, and/or facial defect. The craniofacial implant is composed of a material that is sonolucent and exhibits attenuation of less than 6 dB/cm.

9. 发明公开

US20230371989A1 IMPLANT AND GUIDE 审中-公开
公开(公告)号：US20230371989A1
公开(公告)日：2023-11-23
申请号：US18362650
申请日：2023-07-31
申请人： Materialise NV
发明人： Guillaume DUBOIS , Patrick GOUDOT , Thomas SCHOUMAN
IPC分类号： A61B17/80 , A61B17/17 , A61F2/28 , A61B17/15 , A61B17/16 , G06T17/00 , A61B34/10 , A61B17/68
CPC分类号： A61B17/8061 , A61B17/1728 , A61F2/2803 , A61B17/151 , A61B17/1673 , A61F2/2875 , A61B17/176 , G06T17/00 , A61B34/10 , A61B17/8071 , A61F2002/2889 , A61B2034/102 , A61B2017/681 , A61F2002/2882
摘要： A method for configuring a surgical guide and an associated implant. The implant and surgical guide are for maxillofacial osteosynthesis. Three-dimensional models of the pre- and post-operative anatomy are used to define attachment points. These attachment points are used to determine a structure for the implant and surgical guide.

10. 发明申请

US20180008746A1 METHOD FOR RESTORING BONE USING SHAPEABLE BONE GRAFT SUBSTITUTE AND INSTRUMENTS FOR DELIVERY THEREOF 审中-公开
公开(公告)号：US20180008746A1
公开(公告)日：2018-01-11
申请号：US15710071
申请日：2017-09-20
申请人： Orthovita, Inc.
发明人： Charanpreet S. Bagga , Theodore D. Clineff , Erik M. Erbe , Michael W. Paris , Gina M. Nagvajara , Antony Koblish
IPC分类号： A61L27/54 , A61B17/88 , A61F2/28 , A61L27/50 , A61L27/46 , A61B17/68 , A61L27/20 , A61L27/56 , A61B17/70 , A61L27/58 , A61F2/34 , A61F2/30 , A61F2/46 , A61F2/38
CPC分类号： A61L27/54 , A61B17/68 , A61B17/7095 , A61B17/8822 , A61F2/28 , A61F2/2803 , A61F2/2875 , A61F2/3094 , A61F2/34 , A61F2/389 , A61F2/4601 , A61F2/4644 , A61F2002/2817 , A61F2002/2835 , A61F2002/2882 , A61F2002/30062 , A61F2002/30151 , A61F2002/30224 , A61F2002/30235 , A61F2002/30247 , A61F2002/30261 , A61F2002/30622 , A61F2002/30677 , A61F2002/30736 , A61F2002/30838 , A61F2210/0004 , A61F2210/0085 , A61F2230/0017 , A61F2230/0069 , A61F2230/0071 , A61F2230/0082 , A61F2310/00293 , A61F2310/00365 , A61L27/20 , A61L27/46 , A61L27/50 , A61L27/56 , A61L27/58 , A61L2400/06 , A61L2400/16 , A61L2430/02 , C08L89/06
摘要： Disclosed is directed to a method for restoring bone in an animal comprising: accessing a site to be restored; loading a syringe body with a flowable bone graft material; mating the syringe body with a delivery tube; positioning the delivery tube at the site to be restored; using a syringe piston to advance the said material into the delivery tube; using the syringe piston or a plunger that mates with the delivery tube after removal of the syringe body to deliver the bone graft to the site at a force of less than 50 lbs. extrusion force; wherein said material is at least 75% porous with a mineral to polymer ratio of 80:20.

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