专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20120015355A1 SIZE STANDARDS FOR USE IN NUCLEIC ACID ANALYSIS 有权
标题翻译：用于核酸分析的大小标准
公开(公告)号：US20120015355A1
公开(公告)日：2012-01-19
申请号：US13000597
申请日：2009-06-29
申请人： Valerie Carol Tucker , Pieris Koumi , Andrew Hopwood , Keith Elliot
发明人： Valerie Carol Tucker , Pieris Koumi , Andrew Hopwood , Keith Elliot
IPC分类号： C12Q1/68 , C25B7/00 , C07H21/00
CPC分类号： C12Q1/68 , C12Q2565/125 , C12Q2545/101 , C12Q2525/204 , C12Q2537/143
摘要： A size standard, kit includes a size standard, method of defining a size standard and method of analysis using a size standard. The size standard is intended to include size standard elements which have a size greater than and/or less than and/or different from the components of a sample which are to be sized. This means that the same characteristic unit, such as a dye, can be used to label the component and the size standard. A further characteristic unit, from amongst a limited number of such characteristic units is liberated from use only on size standards for use on components. The method is therefore particularly useful in multiplex amplification of STRs.
摘要翻译：尺寸标准，套件包括尺寸标准，使用尺寸标准定义尺寸标准的方法和分析方法。尺寸标准旨在包括具有大于和/或小于和/或不同于尺寸的样品的组分的尺寸的尺寸标准元件。这意味着可以使用相同的特征单元，例如染料来标记组分和尺寸标准。从有限数量的这种特征单元中的另一个特征单元仅在组件上使用的尺寸标准上被使用。因此，该方法在STR的多重扩增中特别有用。

2. 发明申请

US20120013439A1 METHODS AND APPARATUS FOR COMPARISON 有权
标题翻译：比较方法和装置
公开(公告)号：US20120013439A1
公开(公告)日：2012-01-19
申请号：US13123879
申请日：2009-10-19
申请人： Cedric Neumann , Ian Evett
发明人： Cedric Neumann , Ian Evett
IPC分类号： G06F7/04
CPC分类号： G06K9/00093
摘要： An apparatus and a computer implemented method compare a first representation of an identifier with a second representation of an identifier to establish a likelihood ratio considering the probability the first representation and second representation originate from the same identifier and the probability of the first representation and second representation originate from different identifiers. The approach generates one or more variant expressions from the first representation, second representation and other representations. A boundary around the expression of the second representation is used to establish the number of the variant expressions of the expression of the first representation within it and the number of variant expressions of the expressions of the other representations within it and so provide the measure of comparison between the first representation of the identifier and the second representation of the identifier from the first value and second value.
摘要翻译：一种装置和计算机实现的方法将标识符的第一表示与标识符的第二表示进行比较，以便考虑第一表示和第二表示来自相同标识符的概率以及第一表示和第二表示的概率来建立似然比来自不同的标识符。该方法从第一表示，第二表示和其他表示生成一个或多个变体表达。围绕第二表示的表达的边界用于确定其内的第一表示的表达式的变体表达式的数量以及其内的其他表示的表达式的变体表达式的数量，并且因此提供比较的度量在第一值和第二值之间的标识符的第一表示和标识符的第二表示之间。

3. 发明授权

US07668660B2 Analysis of DNA 有权
标题翻译： DNA分析
公开(公告)号：US07668660B2
公开(公告)日：2010-02-23
申请号：US10564682
申请日：2004-07-09
申请人： Peter Gill , Amanda Kirkham
发明人： Peter Gill , Amanda Kirkham
IPC分类号： G01N33/48
CPC分类号： C12Q1/6809
摘要： The invention provides methods for providing information on the probability of DNA samples being contaminated over days, weeks and months in relation to collection, processing and analysis of DNA samples. Methods are also provided for analysing the likelihood of a result arising due to contamination and/or determining the analysis protocol to be applied to a DNA sample and/or methods of operating databases, particularly containing DNA profiles.Improvements in accounting for sporadic and undetected contamination and improvements in the operation of DNA sampling of analysis are provided by the invention.
摘要翻译：本发明提供了关于DNA样品在DNA样品的收集，处理和分析方面在几天，几周和几个月内被污染的可能性的信息的方法。还提供了用于分析由于污染引起的结果的可能性和/或确定要应用于DNA样品的分析方案和/或操作数据库的方法，特别是含有DNA谱的方法。通过本发明提供了散发性和未检测到的污染物的改进，以及分析的DNA取样操作的改进。

4. 发明申请

US20090234621A1 METHOD OF OPTIMIZING PARAMETERS IN THE ENTIRE PROCESS OF ANALYSING A DNA CONTAINING SAMPLE AND METHOD OF MODELING SAID PROCESS 审中-公开
标题翻译：在分析样品的DNA的整个过程中优化参数的方法和建模过程的方法
公开(公告)号：US20090234621A1
公开(公告)日：2009-09-17
申请号：US11720721
申请日：2005-12-05
申请人： Peter Gill , James Curran
发明人： Peter Gill , James Curran
IPC分类号： G06F17/10 , G06G7/48 , G06F19/00 , G01N33/48
CPC分类号： C12Q1/6851 , G16B40/00 , G16B45/00 , C12Q2537/165
摘要： A method of optimizing one or more parameters in a process for considering a DNA containing sample using a method of modeling and a method of modeling itself are provided. The method of modeling the process for considering a DNA containing sample uses a graphical model. The model seeks to provide one or more optimized parameters for the consideration process. The methods aim to consider the whole process, for instance, the number of cells required for the process and/or the extraction efficiency and/or the sub-sample volume relative to the sample volume and/or the amplification efficiency and/or the optimum number of amplification cycles and/or the effect of degradation on the amount of amplifiable DNA in the sample.
摘要翻译：提供了一种在使用建模方法考虑含DNA样品的过程中优化一个或多个参数的方法和自身建模方法。用于考虑含DNA样品的过程进行建模的方法使用图形模型。该模型试图为考虑过程提供一个或多个优化参数。该方法旨在考虑整个过程，例如，相对于样品体积和/或放大效率和/或最佳值，该方法所需的细胞数量和/或提取效率和/或亚样品体积扩增循环数和/或降解对样品中可扩增DNA量的影响。

5. 发明申请

US20150111215A1 SAMPLE HANDLING 审中-公开
标题翻译：样品处理
公开(公告)号：US20150111215A1
公开(公告)日：2015-04-23
申请号：US14283709
申请日：2014-05-21
申请人： FORENSIC SCIENCE SERVICE LIMITED
发明人： Gary ROSS , Sebastian WETHERALL , Owen EVANS , Andrew HOPWOOD , Nina MORAN
IPC分类号： G01N1/44 , C12N15/10 , B01L3/00 , C12Q1/68 , B01L7/00
CPC分类号： G01N1/44 , A61B10/0051 , A61B10/0096 , A61B2010/0216 , B01L3/502715 , B01L3/5029 , B01L3/50825 , B01L7/52 , B01L2200/025 , B01L2200/0621 , B01L2200/0689 , B01L2200/141 , B01L2200/147 , B01L2200/16 , B01L2300/041 , B01L2300/044 , B01L2300/049 , B01L2300/0672 , B01L2300/069 , B01L2300/0832 , B01L2300/0861 , B01L2300/1805 , B01L2400/0475 , B01L2400/0478 , B01L2400/0644 , B01L2400/0683 , C12N15/1003 , C12Q1/6806 , G01N1/28
摘要： The invention provides containers and methods of use for the storage, transportation and preparation of samples, such as DNA samples for analysis. The container is pre-provided with the reagents in sealed chambers. The sample can be introduced and the container manipulated to release the reagents, provide the necessary conditions and give a fully prepared sample. The container can then be engaged with an analysis device to identify characteristics of the sample or perform other operations thereon.
摘要翻译：本发明提供用于储存，运输和制备样品的容器和方法，例如用于分析的DNA样品。容器在密封室中预先装有试剂。可以引入样品并操作容器以释放试剂，提供必要的条件并给出完全准备的样品。然后可以将容器与分析装置接合以识别样品的特征或对其进行其它操作。

6. 发明授权

US08983153B2 Methods and apparatus for comparison 有权
标题翻译：比较方法和装置
公开(公告)号：US08983153B2
公开(公告)日：2015-03-17
申请号：US13123879
申请日：2009-10-19
申请人： Cedric Neumann , Ian Evett
发明人： Cedric Neumann , Ian Evett
IPC分类号： G06K9/00
CPC分类号： G06K9/00093
摘要： An apparatus and a computer implemented method compare a first representation of an identifier with a second representation of an identifier to establish a likelihood ratio considering the probability the first representation and second representation originate from the same identifier and the probability of the first representation and second representation originate from different identifiers. The approach generates one or more variant expressions from the first representation, second representation and other representations. A boundary around the expression of the second representation is used to establish the number of the variant expressions of the expression of the first representation within it and the number of variant expressions of the expressions of the other representations within it and so provide the measure of comparison between the first representation of the identifier and the second representation of the identifier from the first value and second value.
摘要翻译：一种装置和计算机实现的方法将标识符的第一表示与标识符的第二表示进行比较，以便考虑第一表示和第二表示来自相同标识符的概率以及第一表示和第二表示的概率来建立似然比来自不同的标识符。该方法从第一表示，第二表示和其他表示生成一个或多个变体表达。围绕第二表示的表达的边界用于确定其内的第一表示的表达式的变体表达式的数量以及其内的其他表示的表达式的变体表达式的数量，并且因此提供比较的度量在第一值和第二值之间的标识符的第一表示和标识符的第二表示之间。

7. 发明申请

US20130316335A1 SAMPLE HANDLING 审中-公开
公开(公告)号：US20130316335A1
公开(公告)日：2013-11-28
申请号：US13892844
申请日：2013-05-13
申请人： GRID XITEK LIMITED , FORENSIC SCIENCE SERVICE LIMITED
发明人： Gary ROSS , Sebastian WETHERALL , Owen EVANS , Andrew HOPWOOD , Nina MORAN
IPC分类号： G01N1/28
CPC分类号： G01N1/44 , A61B10/0051 , A61B10/0096 , A61B2010/0216 , B01L3/502715 , B01L3/5029 , B01L3/50825 , B01L7/52 , B01L2200/025 , B01L2200/0621 , B01L2200/0689 , B01L2200/141 , B01L2200/147 , B01L2200/16 , B01L2300/041 , B01L2300/044 , B01L2300/049 , B01L2300/0672 , B01L2300/069 , B01L2300/0832 , B01L2300/0861 , B01L2300/1805 , B01L2400/0475 , B01L2400/0478 , B01L2400/0644 , B01L2400/0683 , C12N15/1003 , C12Q1/6806 , G01N1/28
摘要： The invention provides containers and methods of use for the storage, transportation and preparation of samples, such as DNA samples for analysis. The container is pre-provided with the reagents in sealed chambers. The sample can be introduced and the container manipulated to release the reagents, provide the necessary conditions and give a fully prepared sample. The container can then be engaged with an analysis device to identify characteristics of the sample or perform other operations thereon.

8. 发明申请

US20120046874A1 CONSIDERATION OF EVIDENCE 审中-公开
标题翻译：考虑证据
公开(公告)号：US20120046874A1
公开(公告)日：2012-02-23
申请号：US13263134
申请日：2010-04-09
申请人： Roberto Puch-Solis , Lauren Rodgers
发明人： Roberto Puch-Solis , Lauren Rodgers
IPC分类号： G06F19/22
CPC分类号： G16B20/00 , G16B40/00
摘要： A computer implemented method of comparing a test sample result set with another sample result set is provided, the method including: providing information for the first result set on the one or more identities detected for a variable characteristic of DNA; providing information for the second result set on the one or more identities detected for a variable characteristic of DNA; and comparing at least a part of the first result set with at least a part of the second result set; and wherein: the comparing includes a likelihood and the likelihood uses a probability density function conditioned on DNA quantity. Further benefits are obtained from the manner in which the probability density function is obtained and/or the use of probability density functions to account for stutter and/or allele dropout.
摘要翻译：提供了一种将测试样本结果集与另一个样本结果集进行比较的计算机实现方法，所述方法包括：为针对DNA的可变特征检测到的一个或多个身份提供关于第一结果集的信息; 提供关于针对DNA的可变特征检测到的一个或多个身份的第二结果集的信息; 以及将所述第一结果集的至少一部分与所述第二结果集的至少一部分进行比较; 并且其中：所述比较包括似然性，所述似然性使用条件为DNA量的概率密度函数。从获得概率密度函数和/或使用概率密度函数来解释口吃和/或等位基因缺失的方式获得进一步的益处。

9. 发明申请

US20100114500A1 ANALYSIS OF DNA 有权
标题翻译： DNA分析
公开(公告)号：US20100114500A1
公开(公告)日：2010-05-06
申请号：US12686174
申请日：2010-01-12
申请人： Peter GILL , Amanda Kirkham
发明人： Peter GILL , Amanda Kirkham
IPC分类号： G06F19/00 , G06F17/18
CPC分类号： C12Q1/6809
摘要： The invention provides methods for providing information on the probability of DNA samples being contaminated over days, weeks and months in relation to collection, processing and analysis of DNA samples. Methods are also provided for analysing the likelihood of a result arising due to contamination and/or determining the analysis protocol to be applied to a DNA sample and/or methods of operating databases, particularly containing DNA profiles.Improvements in accounting for sporadic and undetected contamination and improvements in the operation of DNA sampling of analysis are provided by the invention.
摘要翻译：本发明提供了关于DNA样品在DNA样品的收集，处理和分析方面在几天，几周和几个月内被污染的可能性的信息的方法。还提供了用于分析由于污染引起的结果的可能性和/或确定要应用于DNA样品的分析方案和/或操作数据库的方法，特别是含有DNA谱的方法。通过本发明提供了散发性和未检测到的污染物的改进，以及分析的DNA取样操作的改进。

10. 发明申请

US20140181147A1 DNA MATCHING 审中-公开
标题翻译： DNA匹配
公开(公告)号：US20140181147A1
公开(公告)日：2014-06-26
申请号：US14047525
申请日：2013-10-07
申请人： Forensic Science Service Limited
发明人： Martin BILL
IPC分类号： G06F19/18 , G06F17/30
CPC分类号： G06F16/2462 , G06F16/24578 , G06F16/2468 , G06F16/248 , G16B20/00 , G16B30/00 , G16B50/00 , G16H10/60
摘要： A method of searching a computer database containing a plurality of stored DNA profiles is provided. The method involves generating a search profile formed of two or more allele identities for each of one or more loci, at least one of the allele identities having a limited range of values, with the search profile being compared against the one or more stored DNA profiles from a database to establish matches between the search and stored profile.
摘要翻译：提供了一种搜索包含多个存储的DNA谱的计算机数据库的方法。所述方法涉及生成由两个或多个等位基因身份形成的搜索简档，用于一个或多个基因座中的每一个，所述等位基因身份中的至少一个具有有限的值范围，其中将搜索简档与一个或多个存储的DNA谱从数据库建立搜索和存储的配置文件之间的匹配。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式