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1. 发明授权

US11466373B2 Electrolytic buffer generator 有权
公开(公告)号：US11466373B2
公开(公告)日：2022-10-11
申请号：US15990043
申请日：2018-05-25
申请人： Board of Regents, The University of Texas System , Dionex Corporation
发明人： Purnendu K. Dasgupta , Yongjing Chen , Kannan Srinivasan
IPC分类号： C25B7/00 , B01D61/44 , B01D61/46 , B01D15/16 , G01N30/34
摘要： Buffer generators are described based on electrodialytic devices. The methods of using these devices can generate buffers for diverse applications, including separations, e.g., HPLC and ion chromatography. Also provided are chromatographic devices including the buffer generators, generally located upstream from a chromatography column, sample injector valve or both.

2. 发明授权

US10633747B2 Gas generator 有权
公开(公告)号：US10633747B2
公开(公告)日：2020-04-28
申请号：US16219132
申请日：2018-12-13
申请人： Hsin-Yung Lin
发明人： Hsin-Yung Lin
IPC分类号： C25B1/02 , C25B13/02 , C25B13/04 , C25B7/00 , A61M16/16 , A61M16/10 , A61M16/20
CPC分类号： C25B1/02 , A61M16/10 , A61M16/165 , C25B7/00 , C25B13/02 , C25B13/04 , A61M16/106 , A61M16/201 , A61M2205/21
摘要： The present invention provides a gas generator and comprises an electrolytic cell and a water-blocking device. The electrolytic cell is used for electrolyzing electrolyzed water to generate a gas with hydrogen. The electrolytic cell has an outlet for outputting the gas with hydrogen. The water-blocking device is set on the outlet for preventing the electrolyzed water from flowing out when the electrolytic cell is tilted by a tilt angle. The gas pathway of the invention will be closed by the water-blocking device when the gas generator is toppled, thereby preventing the electrolyte-rich electrolyzed water from flowing out.

3. 发明授权

US09162961B2 Process for manufacturing succinic acid 有权
标题翻译：制备琥珀酸的方法
公开(公告)号：US09162961B2
公开(公告)日：2015-10-20
申请号：US13578350
申请日：2011-02-14
申请人： Willem Jacob Groot , Jan Van Breugel
发明人： Willem Jacob Groot , Jan Van Breugel
IPC分类号： C25B7/00 , C07C27/06 , C07C51/41 , C07C29/149 , C07C51/02 , C07C51/43 , C12P7/46
CPC分类号： C12P7/18 , C07C29/149 , C07C51/02 , C07C51/412 , C07C51/43 , C12P7/46 , C07C31/207 , C07C55/10
摘要： A process for the preparation of succinic acid comprising the steps of: a) providing an aqueous medium comprising magnesium succinate by fermentation of a carbohydrate source, in the presence of a magnesium base; b) processing the aqueous medium wherein the magnesium succinate is treated with a monovalent base, prior to or after a crystallization step, to provide a magnesium base and an aqueous solution comprising a monovalent succinate salt; c) adjusting the concentration of the monovalent succinate salt to between 10 and 35 wt. %; d) subjecting the aqueous solution to water-splitting electrodialysis, to produce a first solution comprising monovalent base and a second solution comprising succinic acid and monovalent succinate salt, the electrodialysis causing conversion of 40 to 95 mole %; e) separating the second solution into succinic acid and the monovalent succinate salt by crystallization; f) recycling the monovalent succinate salt solution of step e) to step d).
摘要翻译：一种制备琥珀酸的方法，包括以下步骤：a）在镁碱存在下，通过发酵碳水化合物源提供包含琥珀酸镁的水性介质; b）在结晶步骤之前或之后，用单价碱处理其中琥珀酸镁的水性介质，以提供镁碱和包含一价琥珀酸盐的水溶液; c）将单价琥珀酸盐的浓度调节至10至35wt。％; d）使水溶液进行水分解电渗析，以产生包含一价碱和包含琥珀酸和一价琥珀酸盐的第二溶液的第一溶液，该电渗析导致40至95摩尔％的转化率; e）通过结晶将第二溶液分离成琥珀酸和单价琥珀酸盐; f）将步骤e）的单价琥珀酸盐溶液再循环到步骤d）。

4. 发明授权

US09115436B2 System for confining and evacuating aerosols of two or three-phases 有权
标题翻译：限制和撤离两相或三相气溶胶的系统
公开(公告)号：US09115436B2
公开(公告)日：2015-08-25
申请号：US13883932
申请日：2011-11-08
申请人： Pedro A. Aylwin Gomez , Cesar A. Calderon Gutierrez
发明人： Pedro A. Aylwin Gomez , Cesar A. Calderon Gutierrez
IPC分类号： C25B7/00 , C25C7/00 , B08B15/00
CPC分类号： C25C7/005 , B08B15/007 , C25C7/00
摘要： A system to confine a space above an electrolyte in a metal electrowinning cell and to evacuate aerosols of two or three phases that are generated in the space, wherein the system confines in a compartmentalized manner a space above the level of the electrolyte adjoining cathode guides attached to a support structure, the cathodes within their guides, an anodic confiner for each anode, which are mounted directly around them, via their central groove of a length equal to the width of the anode, a pair of flexible projections and a pair of angle profiles of rigid material each of which is located on either side of the anodic confiner, wherein all these elements are linked by a multiplicity of coupling elements.
摘要翻译：在金属电解冶金池中限制电解质上方的空间并在空间中排出两相或三相的气溶胶的系统，其中所述系统以间隔的方式限制邻近连接的阴极导体的电解质的水平面上方的空间支撑结构，其引导件内的阴极，用于每个阳极的阳极密封件，其直接安装在其周围，经由其长度等于阳极宽度的中心槽，一对柔性突起和一对角度刚性材料的轮廓分别位于阳极冷凝器的任一侧，其中所有这些元件通过多个连接元件连接。

5. 发明授权

US09108844B2 Method for producing hydrogen chloride or an aqueous solution thereof using untreated salt water, thus produced product, use of the product and electrodialysis system 有权
标题翻译：使用未处理的盐水生产氯化氢或其水溶液的方法，从而生产产品，使用该产品和电渗析系统
公开(公告)号：US09108844B2
公开(公告)日：2015-08-18
申请号：US13805434
申请日：2010-08-27
申请人： Rainer Huss
发明人： Rainer Huss
IPC分类号： B01D61/46 , C01B7/03 , C02F1/469 , C01B7/01 , C25B7/00 , C02F103/06 , C02F103/08
CPC分类号： C01B7/035 , B01D61/46 , B01D2311/263 , B01D2313/12 , B01D2313/16 , B01D2313/32 , C01B7/01 , C02F1/4693 , C02F2103/06 , C02F2103/08 , C02F2201/46115 , C02F2201/46185 , C25B7/00
摘要： A method of producing hydrogen chloride, or an aqueous solution thereof, includes the steps: a) furnishing a first electrolyte containing chloride ions; b) carrying out an electrodialysis, wherein the first electrolyte is subjected to a cathodic reduction resulting in a catholyte, wherein the concentration of chloride ions drops in the first electrolyte, the concentration of hydroxide ions increases in the first electrolyte, and a product in the form of hydrogen chloride or an aqueous solution thereof is produced; c) processing of at least a partial quantity of the catholyte, resulting in the first electrolyte, wherein an untreated saline water is used, the concentration of chloride ions increases in the catholyte and the concentration of hydroxide ions drops in the catholyte; and d) at least partial reuse of the catholyte processed according to step c) as the first electrolyte in step b).
摘要翻译：制备氯化氢或其水溶液的方法包括以下步骤：a）提供含有氯离子的第一电解质; b）进行电渗析，其中第一电解质经历阴极还原，导致阴极电解液，其中氯离子的浓度在第一电解质中滴落，氢氧根离子的浓度在第一电解质中增加，并且产物在生成氯化氢或其水溶液的形式; c）处理至少部分量的阴极电解液，产生第一电解质，其中使用未处理的盐水，氯化物离子浓度在阴极电解液中增加，氢氧根离子的浓度在阴极电解液中下降; 以及d）根据步骤c）处理的阴极电解液至少部分再利用为步骤b）中的第一电解质。

6. 发明授权

US09040234B2 Oligonucleotide analogs as therapeutic agents 有权
标题翻译：寡核苷酸类似物作为治疗剂
公开(公告)号：US09040234B2
公开(公告)日：2015-05-26
申请号：US13218259
申请日：2011-08-25
申请人： Radhakrishnan P. Iyer , John E. Coughlin
发明人： Radhakrishnan P. Iyer , John E. Coughlin
IPC分类号： A61K31/713 , A61K31/7084 , A61P31/00 , A61P31/12 , C07H21/04 , C12Q1/68 , C12Q1/70 , C25B7/00 , G01N27/447 , G01N33/559
CPC分类号： C12N15/1131 , A61K31/7084 , A61K31/713 , C07H21/04 , C12N2310/14 , C12N2310/17 , C12N2310/315 , C12N2320/30
摘要： The invention relates to design of short oligonucleotides and analogs thereof (such as, di-, and trinucleotide compounds) useful for various therapeutic applications. It is believed that the compounds of the invention can be used as antiviral agents, anticancer agents and so on. In certain embodiments, the compounds of the invention can modulate immune-stimulatory pathways and non-TLR pathways. The invention also relates to design modified oligonucleotides for therapeutic applications, by excluding nucleotide segments having off-target effects from the modified oligonucleotides. In another aspect, the invention provides pharmaceutical compositions including one or more compounds of the invention.It is believed that the compounds and compositions as described herein have therapeutic utility against a variety of diseases, including viral diseases, autoimmune diseases (such as, allergy, asthma, and inflammatory disorders) and cancer.
摘要翻译：本发明涉及可用于各种治疗应用的短寡核苷酸及其类似物（例如，二核苷酸和三核苷酸化合物）的设计。据信本发明的化合物可以用作抗病毒剂，抗癌剂等。在某些实施方案中，本发明的化合物可以调节免疫刺激途径和非TLR途径。本发明还涉及用于治疗应用的设计修饰的寡核苷酸，通过从经修饰的寡核苷酸排除具有脱靶效应的核苷酸区段。另一方面，本发明提供包含一种或多种本发明化合物的药物组合物。据信本文所述的化合物和组合物具有针对各种疾病（包括病毒性疾病，自身免疫性疾病（例如过敏，哮喘和炎性疾病））和癌症的治疗效用。

7. 发明授权

US08778229B2 Robust multi particle system for color electrophoretic displays with very low driving voltages comprising a low amount of electrolytes 有权
标题翻译：用于彩色电泳显示器的强大的多粒子系统，具有包含少量电解质的非常低的驱动电压
公开(公告)号：US08778229B2
公开(公告)日：2014-07-15
申请号：US11915014
申请日：2006-05-10
申请人： Patrick John Baesjou , Lucas Josef Maria Schlangen
发明人： Patrick John Baesjou , Lucas Josef Maria Schlangen
IPC分类号： H01B1/12 , C25B7/00
CPC分类号： G02F1/167
摘要： An electrophoretic dispersion with at least two particle species is proposed in which a minimal number (and concentration) of free compounds is present in solution. All chemicals needed to color and stabilize the pigment particles are preferably covalently attached to or within the particles. This enhances the robustness of the system and minimizes the conductivity of the dispersion so that the driving voltage for an electrophoretic display is reduced.
摘要翻译：提出了具有至少两种颗粒物质的电泳分散体，其中游离化合物的最小数量（和浓度）存在于溶液中。颜料颗粒着色和稳定化所需的所有化学品优选共价连接到颗粒内或颗粒内。这增强了系统的鲁棒性并使分散体的电导率最小化，使得电泳显示器的驱动电压降低。

8. 发明授权

US08307994B2 Surface charge enabled nanoporous semi-permeable membrane for desalination 有权
标题翻译：表面电荷使纳米多孔半透膜脱盐
公开(公告)号：US08307994B2
公开(公告)日：2012-11-13
申请号：US12607258
申请日：2009-10-28
申请人： John M. Cotte , Christopher V. Jahnes , Hongbo Peng , Stephen M. Rossnagel
发明人： John M. Cotte , Christopher V. Jahnes , Hongbo Peng , Stephen M. Rossnagel
IPC分类号： B01D71/02 , B01D69/00 , B05D1/00 , B05D3/00 , C25B7/00
CPC分类号： B01D67/0065 , B01D71/022 , B01D2323/283 , B01D2325/021 , Y10T428/249953
摘要： A filter includes a membrane having a plurality of nanochannels formed therein. A first surface charge material is deposited on an end portion of the nanochannels. The first surface charge material includes a surface charge to electrostatically influence ions in an electrolytic solution such that the nanochannels reflect ions back into the electrolytic solution while passing a fluid of the electrolytic solution. Methods for making and using the filter are also provided.
摘要翻译：过滤器包括其中形成有多个纳米通道的膜。第一表面电荷材料沉积在纳米通道的端部上。第一表面电荷材料包括静电地影响电解溶液中的离子的表面电荷，使得纳米通道在通过电解液的流体时将离子反射回电解溶液。还提供了制造和使用过滤器的方法。

9. 发明授权

US08298396B2 Process and apparatus for the production and separation of fermentation products 失效
标题翻译：用于生产和分离发酵产物的方法和设备
公开(公告)号：US08298396B2
公开(公告)日：2012-10-30
申请号：US11661059
申请日：2005-09-02
申请人： Earl Lawrence Vincent Goetheer , Joost van Erkel , Koen Peter Henri Meesters , Roel Johannes Martinus Bisselink
发明人： Earl Lawrence Vincent Goetheer , Joost van Erkel , Koen Peter Henri Meesters , Roel Johannes Martinus Bisselink
IPC分类号： B01D43/00 , C25B7/00 , C12P7/40 , C12P13/04
CPC分类号： C12P7/40 , C12P7/44 , C12P13/04
摘要： The invention is directed to processes and apparatuses for the production of chemical compounds, in particular fermentation products. According to the invention there is provided a process for the production of one or more chemical substances, which process comprises a fermentation step, wherein said substances are formed; and a separation step, wherein at least one pair of electrodes is used to induce a precipitation of said substances, which pair comprises at least one precipitation electrode and at least one counter electrode, through which an electric current is directed is used to precipitate said one or more substances.
摘要翻译：本发明涉及用于生产化合物，特别是发酵产物的方法和装置。根据本发明，提供了一种生产一种或多种化学物质的方法，该方法包括发酵步骤，其中形成所述物质; 和分离步骤，其中使用至少一对电极来诱导所述物质的沉淀，所述物质包括至少一个沉淀电极和至少一个对电极，通过该对电极引导电流以沉淀所述一个或更多的物质。

10. 发明申请

US20120193232A1 PREPARATION METHOD OF ANTI-BACTERIAL COATING ON PLASTIC SURFACE 审中-公开
标题翻译：塑料表面抗菌涂层的制备方法
公开(公告)号：US20120193232A1
公开(公告)日：2012-08-02
申请号：US13352440
申请日：2012-01-18
申请人： Shui Yu , Min-Zen Lee
发明人： Shui Yu , Min-Zen Lee
IPC分类号： C25B7/00 , C23C16/06 , C08F2/48 , C23C14/34 , B05D1/36
CPC分类号： C23C14/205 , B05D1/02 , B05D3/0209 , B05D3/0263 , B05D3/067 , B05D2201/02
摘要： The present invention is a preparation method of an anti-bacterial coating on a plastic surface. A preparation method of an anti-bacterial coating on a plastic surface with a better anti-bacterial effect is provided and comprises putting a plastic substrate into a PVD vacuum device; coating an anti-bacterial metallic layer on the plastic surface; and spray coating an anti-bacterial middle coating on the sample coated with anti-bacterial metallic coating. Utilizing PVD to coat antibacterial layer offsets timeliness of bacterial activity of the organic anti-bacterial coating, which allows the products with double bacterial layers have excellent anti-bacterial and bacteria-inhibited effects during their life spans. The anti-bacterial effect can not only be lasted for a long time, but also achieve high anti-bacterial efficiency (antibacterial rate is more than 99%). The product has excellent function and superior appearance, which is suitable for bath products, electronic devices, domestic appliances, cars and other industries.
摘要翻译：本发明是塑料表面上的抗菌涂层的制备方法。提供了具有更好的抗菌作用的塑料表面上的抗菌涂层的制备方法，包括将塑料基材放入PVD真空装置中; 在塑料表面涂上抗菌金属层; 并在涂有抗菌金属涂层的样品上喷涂抗菌中间涂层。利用PVD涂覆抗菌层，抵消了有机抗菌涂层细菌活性的及时性，使得具有双细菌层的产品在其寿命期间具有优异的抗细菌和细菌抑制作用。抗菌效果不仅可以持续很长时间，而且可以达到高抗菌效率（抗菌率超过99％）。该产品功能优良，外形美观，适用于浴室用品，电子设备，家用电器，汽车等行业。

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