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1. 发明申请

US20070141645A1 Measuring method using whole blood 有权
标题翻译：使用全血的测量方法
公开(公告)号：US20070141645A1
公开(公告)日：2007-06-21
申请号：US11300867
申请日：2005-12-15
申请人： Yoshikazu Okamura , Takashi Kurihara , Hiroyuki Yokoi , Junichi Ogawa
发明人： Yoshikazu Okamura , Takashi Kurihara , Hiroyuki Yokoi , Junichi Ogawa
IPC分类号： G01N33/542
CPC分类号： G01N33/581 , G01N2333/916 , Y10T436/25125 , Y10T436/25375
摘要： A method for measuring an analyte in a whole blood sample comprising the steps of (1) bringing the whole blood sample into contact with a first substance which is carried on an insoluble carrier and specifically binds to the analyte to be measured and a second substance which is labeled with an alkaline phosphatase and specifically binds to the analyte to be measured, and (2) measuring a resulting complex on the basis of an enzyme reaction of the alkaline phosphatase, the measuring step (2) being carried out in the presence of an inhibitor of endogenous alkaline phosphatases, is disclosed.
摘要翻译：一种测定全血样品中的分析物的方法，包括以下步骤：（1）使全血样品与携带在不溶性载体上的第一物质接触并且特异性结合待测量的分析物和第二物质，用碱性磷酸酶标记并且特异性地结合待测量的分析物，和（2）基于碱性磷酸酶的酶反应测量所得的复合物，测量步骤（2）在存在下进行公开了内源性碱性磷酸酶抑制剂。

2. 发明授权

US07749722B2 Measuring method using whole blood 有权
标题翻译：使用全血的测量方法
公开(公告)号：US07749722B2
公开(公告)日：2010-07-06
申请号：US11300867
申请日：2005-12-15
申请人： Yoshikazu Okamura , Takashi Kurihara , Hiroyuki Yokoi , Junichi Ogawa
发明人： Yoshikazu Okamura , Takashi Kurihara , Hiroyuki Yokoi , Junichi Ogawa
IPC分类号： G01N33/53 , G01N1/00
CPC分类号： G01N33/581 , G01N2333/916 , Y10T436/25125 , Y10T436/25375
摘要： A method for measuring an analyte in a whole blood sample comprising the steps of (1) bringing the whole blood sample into contact with a first substance which is carried on an insoluble carrier and specifically binds to the analyte to be measured and a second substance which is labeled with an alkaline phosphatase and specifically binds to the analyte to be measured, and (2) measuring a resulting complex on the basis of an enzyme reaction of the alkaline phosphatase, the measuring step (2) being carried out in the presence of an inhibitor of endogenous alkaline phosphatases, is disclosed.
摘要翻译：一种测定全血样品中的分析物的方法，包括以下步骤：（1）使全血样品与携带在不溶性载体上的第一物质接触并且特异性结合待测量的分析物和第二物质，用碱性磷酸酶标记并且特异性地结合待测量的分析物，和（2）基于碱性磷酸酶的酶反应测量所得的复合物，测量步骤（2）在存在下进行公开了内源性碱性磷酸酶抑制剂。

3. 发明申请

US20130303995A1 MEDICAL INSTRUMENT WITH ATTACHED NEEDLE 审中-公开
标题翻译：带有针头的医用仪器
公开(公告)号：US20130303995A1
公开(公告)日：2013-11-14
申请号：US13825693
申请日：2011-09-06
申请人： Kouichi Tachikawa , Junichi Ogawa
发明人： Kouichi Tachikawa , Junichi Ogawa
IPC分类号： A61M5/34
CPC分类号： A61M5/344 , A61M5/28 , A61M5/32 , A61M5/329 , A61M5/3293 , A61M5/34 , A61M5/343
摘要： A medical instrument with attached needle includes a needle tube having a needle tip capable of piercing a living body and a needle holding member for fixing and holding a middle portion of the needle tube by high frequency welding so that the needle tip protrudes from one end and a proximal portion of the needle tube protrudes from the other end. It also has a seal member composed of an elastic member and provided on an outer circumference of the proximal portion of the needle tube so as to be liquid-tight, and a liquid containing member having a liquid chamber capable of containing a liquid therein. With the proximal portion of the needle tube communicating with the liquid chamber, the seal member is compressed by and clamped between the needle holding member and the liquid containing member.
摘要翻译：具有针的医疗器具包括具有能够刺穿活体的针尖的针管和用于通过高频焊接固定和保持针管的中间部分的针保持部件，使得针尖从一端突出，针管的近端部分从另一端突出。它还具有由弹性构件构成的密封构件，该密封构件设置在针管的基端部的外周上以便液密，并且具有能够在其中容纳液体的液体室的液体容纳构件。由于针筒的近端部与液体室连通，密封部件被针保持部件和液体容纳部件压缩并被夹持。

4. 发明申请

US20130197452A1 MEDICAL INSTRUMENT WITH ATTACHED NEEDLE 审中-公开
标题翻译：带有针头的医用仪器
公开(公告)号：US20130197452A1
公开(公告)日：2013-08-01
申请号：US13825981
申请日：2011-06-09
申请人： Kouichi Tachikawa , Junichi Ogawa
发明人： Kouichi Tachikawa , Junichi Ogawa
IPC分类号： A61M5/34
CPC分类号： A61M5/343 , A61M5/28 , A61M5/329 , A61M5/3293 , A61M5/34 , A61M5/344 , A61M5/346
摘要： A medical instrument with attached needle of the present invention includes: a needle tube having a needle tip capable of piercing a living body; and a seal member composed of an elastic member and provided to hold an outer surface of the needle tube in a liquid-tight manner in a condition where the needle tip protrudes from one end and a proximal portion on a side opposite to the needle tip protrudes from the other end. The instrument also has: a liquid containing section having a liquid chamber capable of containing a liquid therein; and a needle seating section formed at one end of the liquid containing section. The seal member is in contact with an inner surface of the needle seating section and is disposed within the needle seating section in a compressed state. The proximal portion of the needle tube communicates with the liquid chamber.
摘要翻译：本发明的具有针的医疗器具包括：针管，其具有能够刺穿活体的针尖; 以及由弹性构件构成的密封构件，其设置成在针尖从一端突出的状态下以液密方式保持针管的外表面，并且与针尖相反的一侧的基部突出从另一端仪器还具有：具有能够在其中容纳液体的液体室的液体容纳部分; 以及形成在所述液体容纳部的一端的针座部。密封构件与针座部的内表面接触，并且以压缩状态设置在针座部内。针管的近端部分与液体室连通。

5. 外观设计

USD626599S1 Electronic board 有权
标题翻译：电子板
公开(公告)号：USD626599S1
公开(公告)日：2010-11-02
申请号：US29356739
申请日：2010-03-02
申请人： Junichi Ogawa , Atsushi Tani , Toshihiro Nakashima
设计人： Junichi Ogawa , Atsushi Tani , Toshihiro Nakashima

6. 发明申请

US20090143737A1 INDWELLING NEEDLE ASSEMBLY 审中-公开
标题翻译：固定针组件
公开(公告)号：US20090143737A1
公开(公告)日：2009-06-04
申请号：US12300950
申请日：2007-05-10
申请人： Ryoji Kobayashi , Junichi Ogawa , Takato Murashita
发明人： Ryoji Kobayashi , Junichi Ogawa , Takato Murashita
IPC分类号： A61M5/32
CPC分类号： A61M5/158 , A61M25/0612 , A61M25/0618 , A61M25/0637 , A61M39/06 , A61M2005/325 , A61M2039/0673
摘要： An indwelling needle assembly has an inner needle having a sharp point at its tip, an inner needle hub fixed to the base end of the inner needle, a hollow outer needle in which the inner needle is inserted, and a seal section provided in the outer needle hub. In the indwelling needle assembly, the seal section has open/close means having a seal section body with a hole into which the inner needle is insertable, a shutter member for opening and closing the hole, and an urging member for urging the shutter member in the direction to close the hole.
摘要翻译：留置针组件具有在其尖端处具有尖锐点的内针，固定到内针的基端的内针毂，插入有内针的中空外针，以及设置在外侧的密封部针毂。在留置针组合体中，密封部具有开闭装置，该开闭装置具有带有可插入内针的孔的密封部本体，用于打开和关闭该孔的活门部件，以及用于将活门部件推压的推压部件关闭孔的方向。

7. 发明申请

US20080312596A1 Indwelling Needle Assembly 有权
标题翻译：留置针组件
公开(公告)号：US20080312596A1
公开(公告)日：2008-12-18
申请号：US12091369
申请日：2006-10-23
申请人： Takato Murashita , Junichi Ogawa , Ryoji Kobayashi
发明人： Takato Murashita , Junichi Ogawa , Ryoji Kobayashi
IPC分类号： A61M5/32
CPC分类号： A61M5/158 , A61M25/0625 , A61M25/0637 , A61M2005/325
摘要： An indwelling needle assembly includes a stylet having a sharp needlepoint at an end thereof, a stylet hub secured to a base end of the stylet, a hollow outer needle in which the stylet is inserted, an outer needle hub secured to a base end of the outer needle, an opening formed at the base end or at a side of the outer needle hub to communicate with the inner cavity of the outer needle, a seal fitted onto the outer needle hub and in which a hole or slit is provided for insertion of the stylet therein, the hole or slit being formed to become closed when the inserted stylet is extracted, an operating part installed on the outer needle hub to move the stylet and outer needle along the longitudinal direction when the stylet is inserted into the outer needle, and a movement suppresser for stopping or suppressing moving the stylet relative to the seal when the operating part is operated.
摘要翻译：留置针组件包括在其端部具有尖锐针尖的探针，固定到探针的基端的探针轮毂，插入探针的中空外针，固定到所述探针的基端的外针毂外针，形成在外针座的基端或侧面处与外针的内腔连通的开口，安装在外针座上的密封件，其中设有孔或狭缝以插入其中的探针，当插入的探针被取出时，孔或狭缝形成为闭合，当探针插入外针时，安装在外针轮毂上的操作部件沿着纵向方向移动探针和外针，以及当操作部件被操作时用于停止或抑制相对于密封件移动探针的移动抑制器。

8. 外观设计

USD571807S1 Scanner 有权
公开(公告)号：USD571807S1
公开(公告)日：2008-06-24
申请号：US29282476
申请日：2007-07-20
申请人： Junichi Ogawa
设计人： Junichi Ogawa

9. 外观设计

USD443887S1 Copying machine 失效
公开(公告)号：USD443887S1
公开(公告)日：2001-06-19
申请号：US29129005
申请日：2000-09-01
申请人： Junichi Ogawa , Kenji Shioya , Takuya Kuwahara
设计人： Junichi Ogawa , Kenji Shioya , Takuya Kuwahara

10. 发明授权

US09096904B2 Method for determining lymph node metastasis in cancer or risk thereof and rapid determination kit for the same 有权
标题翻译：确定癌症淋巴结转移或其风险的方法及其快速测定试剂盒
公开(公告)号：US09096904B2
公开(公告)日：2015-08-04
申请号：US13322537
申请日：2010-05-27
申请人： Satoru Motoyama , Masatomo Miura , Junichi Ogawa
发明人： Satoru Motoyama , Masatomo Miura , Junichi Ogawa
IPC分类号： C12Q1/68 , C12P19/34 , C07H21/02
CPC分类号： C12Q1/6886 , C12Q2600/112 , C12Q2600/118 , C12Q2600/156 , C12Q2600/158
摘要： The objective of the present invention is to provide a method and a means of rapidly and reliably detecting lymph node metastasis in cancer or the risk of lymph node metastasis. Specifically, the present invention provides a method and a rapid determination kit for detecting lymph node metastasis in cancer or its risk by identifying a certain genetic polymorphism of the human CRP gene, and it is clinically significant in determining the treatment strategy, because effective prediction/determination can be made regarding lymph node metastasis, which is an important phenomenon in cancer progression.
摘要翻译：本发明的目的是提供一种快速可靠地检测癌症淋巴结转移或淋巴结转移风险的方法和手段。具体地说，本发明提供了一种用于通过鉴定人类CRP基因的某些遗传多态性来检测癌症中的淋巴结转移或其风险的方法和快速测定试剂盒，并且在确定治疗策略方面具有临床意义，因为有效的预测/ 可以确定淋巴结转移，这是癌症进展中的重要现象。

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