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    • 7. 发明申请
    • Resorcine Derivatives and Their Use as Pesticides
    • US20090209598A1
    • 2009-08-20
    • US12093543
    • 2006-11-10
    • Michael PuhlMarkus KordesMatthias PohlmanNorbert GötzMichael RackJürgen LangewaldFelix SchneiderDouglas D. AnspaughDeborah L. CulbertsonHassan Oloumi-SadeghiDavid G. Kuhn
    • Michael PuhlMarkus KordesMatthias PohlmanNorbert GötzMichael RackJürgen LangewaldFelix SchneiderDouglas D. AnspaughDeborah L. CulbertsonHassan Oloumi-SadeghiDavid G. Kuhn
    • A01N43/40A01N43/38C07D401/04C07D209/54
    • C07D213/64C07D277/34C07D307/80
    • This invention relates to resorcine derivatives of formula (I) wherein R1 is phenyl or a 5- to 6-membered heteroaromatic ring which may contain 1 to 3 heteroatoms selected from oxygen, nitrogen and sulfur, wherein phenyl or the heteroaromatic ring may be fused to a ring selected from phenyl and a 5- to 6-membered saturated, partially unsaturated or aromatic heterocyclic ring which may contain 1 to 3 heteroatoms selected from oxygen, nitrogen and sulfur, wherein phenyl or the 5- to 6-membered heteroaromatic ring or the respective fused ring systems may be unsubstituted or substituted by any combination of 1 to 6 optionally substituted groups R3, wherein R3 is halogen, cyano, nitro, hydroxy, mercapto, amino, alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, haloalkyl, haloalkenyl, haloalkynyl, halocycloalkyl, halocycloalkenyl, alkoxy, alkenyloxy, alkynyloxy, haloalkoxy, haloalkenyloxy, haloalkynyloxy, alkylthio, alkenylthio, alkynylthio, haloalkylthio, haloalkenylthio, haloalkynylthio, alkylamino, alkenylamino, alkynylamino, dialkylamino, dialkenylamino, dialkynylamino, alkyl-alkenylamino, alkyl-alkynylamino, alkenyl-alkynylamino, trialkylsilyl, or phenyl or a 5- to 7-membered saturated or partially unsaturated heterocyclic ring which may contain 1 to 3 heteroatoms selected from oxygen, sulfur and nitrogen or a 5- to 6-membered heteraromatic ring system which may contain 1 to 4 heteroatoms selected from oxygen, nitrogen and sulfur, which phenyl and which heteroaromatic ring may be bonded via an oxygen or a sulfur atom, or —C(=G)Ra, —C(=G)ORa, —C(=G)NRa2, —C(=G)[N═SRa2], —C(═NORa)Ra, —C(═NORa)NRa2, —C(═NNRa2)Ra, —OC(=G)-OC(=G)ORa, N═SRa2, —NRaC(=G)Ra, —N[C(=G)Ra]2, —NRaC(=G)ORa, —C(=G)NRa—NRa2, —C(=G)NRa—NRa[C(=G)Ra], —NRa—C(=G)NRa2, —NRa—NRaC(=G)Ra, —NRa—N[C(=G)Ra]2, —N[(C=G)Ra]—NRa2, —NRa—NRa[(C=G)GRa], —NRa[(C=G)NRa2, —NRa[C═NRa]Ra, —NRa(C═NRa)NRa2, —O—NRa2, —O—NRa(C=G)Ra, —SO2NRa2, —NRaSO2Ra, —S(═O)Ra, —S(═O)2Ra, —SO2ORa, or —OSO2Ra, wherein G is oxygen or sulfur and Ra is as defined in the description, R2 is hydrogen, halogen, cyano, alkyl, haloalkyl, alkenyl, haloalkenyl, alkynyl, haloalkynyl, alkoxy, or haloalkoxy, x is 2, 3, 4, 5, 6, or 7, or the diastereomers, enantiomers, salts or N-oxides thereof, with the proviso that R1 is not 5-chloro-2,2,-dimethyl-2,3-dihydrobenzo[b]furan-7-yl when R2 is hydrogen and x is 3 or 4, processes and intermediates for the preparation of compounds I, use of compounds I for combating insects, acarids, or nematodes, and a method for treating, controlling, preventing or protecting animals against infestation or infection by parasites using compounds I.
    • 8. 发明申请
    • Quinoline Derivatives and Their Use as Pesticides
    • 喹啉衍生物及其作为农药的用途
    • US20090029855A1
    • 2009-01-29
    • US12282608
    • 2007-03-12
    • Michael PuhlWassilios GrammenosJoachim RheinheimerJan Klaas LohmannMichael RackLiliana Parra RapadoChristopher KoradinJurgen LangewaldDeborah L. CulbertsonDouglas D. AnspaughHassan Oloumi-SadeghiHenry Van Tuyl CotterDavid G. Kuhn
    • Michael PuhlWassilios GrammenosJoachim RheinheimerJan Klaas LohmannMichael RackLiliana Parra RapadoChristopher KoradinJurgen LangewaldDeborah L. CulbertsonDouglas D. AnspaughHassan Oloumi-SadeghiHenry Van Tuyl CotterDavid G. Kuhn
    • A01N25/26C07D215/14A01N43/42A01N59/26A01P5/00A01P7/04
    • C07D215/12C07D215/60
    • This invention relates to quinoline derivatives of formula I wherein R1, R2, R3 are each independently halogen, hydroxy, cyano, amino, nitro, C1-C6-alkyl, C2-C6-alkenyl, C2-C6-alkynyl, C3-C7-cycloalkyl, C3-C7-cycloalkyl-C1-C4-alkyl, C1-C6-alkoxy, C2-C6-alkenyloxy, C2-C6-alkynyloxy, C1-C4-alkoxy-C1-C4-alkoxy, C3-C7-cycloalkyl-C1-C4-alkoxy, C(OH)(CF3)2, C1-C6-haloalkyl, C1-C6-haloalkoxy, C1-C6-alkylthio, C1-C6-haloalkylthio, C1-C6-alkylsulfinyl, C1-C6-haloalkylsulfinyl, C1-C6-alkylsulfonyl, C1-C6-haloalkylsulfonyl, C(Ra)═O, C(Ra)═NORb, C(═O)ORx, or C(═O)NRxRy; Ra is hydrogen or C1-C4-alkyl; Rb is hydrogen, C1-C4-alkyl, C2-C4-alkenyl, C2-C4-alkynyl, C1-C4-haloalkyl, or C2-C4-haloalkenyl; Rx, Ry are each independently hydrogen, C1-C4-alkyl, C1-C4-haloalkyl, C1-C4-alkoxy-C1-C4-alkyl, C1-C4-thioalkyl-C1-C4-alkyl, C1-C4-alkyl-S(═O)C1-C4-alkyl, C1-C4-alkyl-S(═O)2C1-C4-alkyl, C3-C6-cyloalkyl, C1-C4-alkyl-C3-C6-cycloalkyl, C3-C6-alkenyl, C3-C6-alkinyl; R4, R5, R6, R7 are each independently hydrogen, halogen, cyano, amino, nitro, hydroxy, C1-C6-alkyl, C1-C6-alkoxy, C1-C6-haloalkyl, C1-C6-haloalkoxy, C1-C6-alkylthio, C1-C6-haloalkylthio, C1-C6-alkylsulfinyl, C1-C6-haloalkylsulfinyl, C1-C6-alkylsulfonyl, C1-C6-haloalkylsulfonyl, or C(═O)ORc; Rc is hydrogen, C1-C6-alkyl, C2-C6-alkenyl, or C2-C6-alkinyl; m and n are each independently 1, 2, 3, 4, or 5; p is 0, 1, 2, 3, 4, or 5; and the N-oxides, enantiomers, diastereomers and salts thereof, processes and intermediates for the preparation of compounds I, use of compounds I for combating insects, acarids, or nematodes and a method for treating, controlling, preventing or protecting animals against infestation or infection by parasites using compounds I.
    • 本发明涉及式I的喹啉衍生物,其中R 1,R 2,R 3各自独立地为卤素,羟基,氰基,氨基,硝基,C 1 -C 6烷基,C 2 -C 6 - 烯基,C 2 -C 6炔基,C 3 -C 7 - 环烷基,C 3 -C 7 - 环烷基-C 1 -C 4 - 烷基,C 1 -C 6 - 烷氧基,C 2 -C 6 - 烯氧基,C 2 -C 6 - 炔氧基,C 1 -C 4烷氧基-C 1 -C 4烷氧基,C 3 -C 7 - 环烷基 - C 1 -C 6烷氧基,C(OH)(CF 3)2,C 1 -C 6卤代烷基,C 1 -C 6卤代烷氧基,C 1 -C 6烷硫基,C 1 -C 6卤代烷硫基,C 1 -C 6烷基亚磺酰基, C 1 -C 6烷基磺酰基,C 1 -C 6卤代烷基磺酰基,C(R a)-O,C(R a)-NOR b,C(-O)OR x或C(-O)NR x R y; R a是氢或C 1 -C 4 - 烷基; R b是氢,C 1 -C 4 - 烷基,C 2 -C 4 - 烯基,C 2 -C 4 - 炔基,C 1 -C 4卤代烷基或C 2 -C 4 - 卤代烯基; R x,R y各自独立地为氢,C 1 -C 4 - 烷基,C 1 -C 4 - 卤代烷基,C 1 -C 4 - 烷氧基-C 1 -C 4烷基,C 1 -C 4 - 硫代烷基-C 1 -C 4烷基,C 1 -C 4烷基 - S(-O)C 1 -C 4 - 烷基,C 1 -C 4烷基-S(-O)2 C 1 -C 4烷基,C 3 -C 6 - 环烷基,C 1 -C 4烷基-C 3 -C 6环烷基,C 3 -C 6 - 烯基,C 3 -C 6 - 炔基; R4,R5,R6,R7各自独立地为氢,卤素,氰基,氨基,硝基,羟基,C1-C6-烷基,C1-C6-烷氧基,C1-C6-卤代烷基,C1-C6-卤代烷氧基,C1-C6- C 1 -C 6烷基亚磺酰基,C 1 -C 6烷基磺酰基,C 1 -C 6卤代烷基磺酰基或C(-O)OR c; R c是氢,C 1 -C 6 - 烷基,C 2 -C 6 - 烯基或C 2 -C 6 - 炔基; m和n各自独立地为1,2,3,4或5; p是0,1,2,3,4或5; 及其N-氧化物,对映异构体,非对映异构体及其盐,制备化合物I的方法和中间体,化合物I用于防治昆虫,螨虫或线虫的用途,以及用于治疗,控制,预防或保护动物免受感染或 使用化合物I的寄生虫感染