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    • 1. 发明申请
    • Resorcine Derivatives and Their Use as Pesticides
    • US20090209598A1
    • 2009-08-20
    • US12093543
    • 2006-11-10
    • Michael PuhlMarkus KordesMatthias PohlmanNorbert GötzMichael RackJürgen LangewaldFelix SchneiderDouglas D. AnspaughDeborah L. CulbertsonHassan Oloumi-SadeghiDavid G. Kuhn
    • Michael PuhlMarkus KordesMatthias PohlmanNorbert GötzMichael RackJürgen LangewaldFelix SchneiderDouglas D. AnspaughDeborah L. CulbertsonHassan Oloumi-SadeghiDavid G. Kuhn
    • A01N43/40A01N43/38C07D401/04C07D209/54
    • C07D213/64C07D277/34C07D307/80
    • This invention relates to resorcine derivatives of formula (I) wherein R1 is phenyl or a 5- to 6-membered heteroaromatic ring which may contain 1 to 3 heteroatoms selected from oxygen, nitrogen and sulfur, wherein phenyl or the heteroaromatic ring may be fused to a ring selected from phenyl and a 5- to 6-membered saturated, partially unsaturated or aromatic heterocyclic ring which may contain 1 to 3 heteroatoms selected from oxygen, nitrogen and sulfur, wherein phenyl or the 5- to 6-membered heteroaromatic ring or the respective fused ring systems may be unsubstituted or substituted by any combination of 1 to 6 optionally substituted groups R3, wherein R3 is halogen, cyano, nitro, hydroxy, mercapto, amino, alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, haloalkyl, haloalkenyl, haloalkynyl, halocycloalkyl, halocycloalkenyl, alkoxy, alkenyloxy, alkynyloxy, haloalkoxy, haloalkenyloxy, haloalkynyloxy, alkylthio, alkenylthio, alkynylthio, haloalkylthio, haloalkenylthio, haloalkynylthio, alkylamino, alkenylamino, alkynylamino, dialkylamino, dialkenylamino, dialkynylamino, alkyl-alkenylamino, alkyl-alkynylamino, alkenyl-alkynylamino, trialkylsilyl, or phenyl or a 5- to 7-membered saturated or partially unsaturated heterocyclic ring which may contain 1 to 3 heteroatoms selected from oxygen, sulfur and nitrogen or a 5- to 6-membered heteraromatic ring system which may contain 1 to 4 heteroatoms selected from oxygen, nitrogen and sulfur, which phenyl and which heteroaromatic ring may be bonded via an oxygen or a sulfur atom, or —C(=G)Ra, —C(=G)ORa, —C(=G)NRa2, —C(=G)[N═SRa2], —C(═NORa)Ra, —C(═NORa)NRa2, —C(═NNRa2)Ra, —OC(=G)-OC(=G)ORa, N═SRa2, —NRaC(=G)Ra, —N[C(=G)Ra]2, —NRaC(=G)ORa, —C(=G)NRa—NRa2, —C(=G)NRa—NRa[C(=G)Ra], —NRa—C(=G)NRa2, —NRa—NRaC(=G)Ra, —NRa—N[C(=G)Ra]2, —N[(C=G)Ra]—NRa2, —NRa—NRa[(C=G)GRa], —NRa[(C=G)NRa2, —NRa[C═NRa]Ra, —NRa(C═NRa)NRa2, —O—NRa2, —O—NRa(C=G)Ra, —SO2NRa2, —NRaSO2Ra, —S(═O)Ra, —S(═O)2Ra, —SO2ORa, or —OSO2Ra, wherein G is oxygen or sulfur and Ra is as defined in the description, R2 is hydrogen, halogen, cyano, alkyl, haloalkyl, alkenyl, haloalkenyl, alkynyl, haloalkynyl, alkoxy, or haloalkoxy, x is 2, 3, 4, 5, 6, or 7, or the diastereomers, enantiomers, salts or N-oxides thereof, with the proviso that R1 is not 5-chloro-2,2,-dimethyl-2,3-dihydrobenzo[b]furan-7-yl when R2 is hydrogen and x is 3 or 4, processes and intermediates for the preparation of compounds I, use of compounds I for combating insects, acarids, or nematodes, and a method for treating, controlling, preventing or protecting animals against infestation or infection by parasites using compounds I.
    • 5. 发明申请
    • Malononitrile Compounds
    • 丙二腈化合物
    • US20090326012A1
    • 2009-12-31
    • US12158507
    • 2006-12-13
    • Matthias PohlmanMichael HofmannHenricus Maria Martinus BastiaansMichael RackDeborah L. CulbertsonHassan Oloumi-SadeghiTakeo HokamaChristopher PalmerJürgen Langewald
    • Matthias PohlmanMichael HofmannHenricus Maria Martinus BastiaansMichael RackDeborah L. CulbertsonHassan Oloumi-SadeghiTakeo HokamaChristopher PalmerJürgen Langewald
    • A61K31/44C07D271/06C07D271/10C07D277/04A01N43/82A01N43/78C07D401/04
    • C07C323/60A01N37/34A01N43/10A01N43/28A01N43/78A01N43/80A01N43/82C07C255/20C07C255/37C07C317/44C07C317/46C07C323/62C07D213/61C07D235/16C07D261/08C07D271/06C07D277/32C07D333/28
    • Compounds of formula I wherein X is O or S(═O)n; n is 0, 1 or 2; R1 is optionally substituted alkyl, haloalkyl, alkenyl, haloalkenyl, alkynyl, haloalkynyl, cycloalkyl, halocycloalkyl, cycloalkenyl, halocycloalkenyl, phenyl, hetaryl, phenylalkyl, hetaryl alkyl, optionally fused to phenyl, hetaryl or heterocyclyl; A is —NRb2, —C(=G)GRb, —C(=G)NRb2, —C(═NORb)Rb, C(=G)[N═SRb2], —C(=G)NRb—NR2, C2-C6-alkandiyl, C2-C6-alkenediyl, C1-C3-alkyl-G-C1-C3-alkyl, wherein Rb is as defined in the description, or optionally substituted phenyl, hetaryl, heterocyclyl, optionally fused to phenyl or heterocyclyl; B is an optionally substituted saturated or partially unsaturated hydrocarbon chain with 1 to 3 carbon chain atoms; D is an optionally substituted saturated or partially unsaturated hydrocarbon chain with 1 to 5 carbon chain atoms or C3-C6-cycloalkyl; G is oxygen or sulfur; or the enantiomers or diastereomers or salts or N-oxides thereof, processes for preparing the compounds I, pesticidal compositions and synergistic mixtures comprising compounds I, methods for the control of insects, acarids or nematodes by contacting the pests or their food supply, habitat or breeding grounds with a pesticidally effective amount of compounds formula I, and a method for treating, controlling, preventing or protecting animals against infestation or infection by parasites which comprises orally, topically or parenterally administering or applying to the animals a parasiticidally effective amount of compounds of formula I.
    • 其中X为O或S(-O)n的式I化合物; n为0,1或2; R1是任选被取代的烷基,卤代烷基,烯基,卤代烯基,炔基,卤代炔基,环烷基,卤代环烷基,环烯基,卤代环烯基,苯基,杂芳基,苯基烷基,杂芳基烷基,任选地稠合到苯基,杂芳基或杂环基; A是-NR b2,-C(= G)GRb,-C(= G)NRb2,-C(-NORb)Rb,C(= G)[N-SRb2],-C(= G)NRb-NR2, C 2 -C 6 - 亚烷基,C 2 -C 6 - 亚烯基,C 1 -C 3烷基-G-C 1 -C 3 - 烷基,其中R b如说明书中所定义,或任选取代的苯基,杂芳基,杂环基,任选地稠合至苯基或杂环基 ; B是具有1至3个碳链原子的任选取代的饱和或部分不饱和烃链; D是具有1至5个碳原子的任选取代的饱和或部分不饱和烃链或C 3 -C 6环烷基; G是氧或硫; 或其对映异构体或非对映异构体或其盐或N-氧化物,制备化合物I的方法,农药组合物和包含化合物I的协同混合物,通过接触害虫或其食物供应,栖息地或昆虫或昆虫的方法来控制昆虫,螨虫或线虫 具有杀虫有效量的式I化合物的繁殖地,以及用于治疗,控制,预防或保护动物免受寄生虫侵扰或感染的方法,其包括口服,局部或肠胃外给予动物杀寄生虫有效量的化合物 公式一
    • 6. 发明申请
    • Pesticidal Active Mixtures Comprising Aminothiazoline Compounds
    • 包括氨基噻唑啉化合物的杀虫活性混合物
    • US20100056469A1
    • 2010-03-04
    • US12528686
    • 2008-02-22
    • Jürgen LangewaldMarkus KordesDeborah L. CulbertsonDouglas D. Anspaugh
    • Jürgen LangewaldMarkus KordesDeborah L. CulbertsonDouglas D. Anspaugh
    • A01N43/16A01N43/88A01N43/40A01N43/78A01N43/56A01N47/28A01N47/34C07D277/06
    • A01N43/78A01N43/56A01N43/58A01N43/707A01N43/90A01N47/02A01N51/00A01N53/00A01N2300/00
    • Pesticidal mixtures comprising aminothiazoline compounds The present invention relates to pesticidal mixtures comprising as active compounds 1) at least one aminothiazoline compound I of the Formula (I) wherein R1, R2, R3, R4, R5 and R6 are defined in the description; and 2) at least one active compound II selected from a group A comprising acetylcholine esterase inhibitors, GABA-gated chloride channel antagonists, sodium channel modulators, nicotinic acetylcholine receptor agonists/antagonists, chloride channel activators, juvenile hormone mimics, compounds affecting the oxidative phosphorylation, inhibitors of the chitin biosynthesis, moulting disruptors, inhibitors of the MET, voltage-dependent sodium channelblockers, inhibitors of the lipidsynthesis and other compounds as defined in the description, in synergistically effective amounts. The invention relates further to methods and use of these mixtures for combating insects, arachnids or nematodes in and on plants, and for protecting such plants being infested with pests, especially also for protecting seeds.
    • 包含氨基噻唑啉化合物的杀虫混合物本发明涉及包含作为活性化合物的杀虫混合物1)至少一种式(I)的氨基噻唑啉化合物I,其中R 1,R 2,R 3,R 4,R 5和R 6在说明书中定义; 和2)选自包括乙酰胆碱酯酶抑制剂,GABA门控氯化物通道拮抗剂,钠通道调节剂,烟碱乙酰胆碱受体激动剂/拮抗剂,氯化物通道激活剂,幼年激素模拟物,影响氧化磷酸化的化合物的组A中的至少一种活性化合物II ,甲壳质生物合成抑制剂,脱毛破坏剂,MET抑制剂,电压依赖性钠通道阻滞剂,脂质合成抑制剂和描述中定义的其它化合物,具有协同有效量。 本发明进一步涉及这些混合物用于防治植物中和植物上的昆虫,蜘蛛或线虫的方法和用途,并且还用于保护被害虫侵染的植物,特别是用于保护种子。
    • 8. 发明授权
    • Pesticidal active mixtures comprising aminothiazoline compounds
    • 包含氨基噻唑啉化合物的杀虫活性混合物
    • US08153560B2
    • 2012-04-10
    • US12528686
    • 2008-02-22
    • Jürgen LangewaldMarkus KordesDeborah L. CulbertsonDouglas D. Anspaugh
    • Jürgen LangewaldMarkus KordesDeborah L. CulbertsonDouglas D. Anspaugh
    • A01N43/78C07D277/04
    • A01N43/78A01N43/56A01N43/58A01N43/707A01N43/90A01N47/02A01N51/00A01N53/00A01N2300/00
    • Pesticidal mixtures comprising aminothiazoline compounds The present invention relates to pesticidal mixtures comprising as active compounds 1) at least one aminothiazoline compound I of the Formula (I) wherein R1, R2, R3, R4, R5 and R6 are defined in the description; and 2) at least one active compound II selected from a group A comprising acetylcholine esterase inhibitors, GABA-gated chloride channel antagonists, sodium channel modulators, nicotinic acetylcholine receptor agonists/antagonists, chloride channel activators, juvenile hormone mimics, compounds affecting the oxidative phosphorylation, inhibitors of the chitin biosynthesis, moulting disruptors, inhibitors of the MET, voltage-dependent sodium channel blockers, inhibitors of the lipidsynthesis and other compounds as defined in the description, in synergistically effective amounts. The invention relates further to methods and use of these mixtures for combating insects, arachnids or nematodes in and on plants, and for protecting such plants being infested with pests, especially also for protecting seeds.
    • 包含氨基噻唑啉化合物的杀虫混合物本发明涉及包含作为活性化合物的杀虫混合物1)至少一种式(I)的氨基噻唑啉化合物I,其中R 1,R 2,R 3,R 4,R 5和R 6在说明书中定义; 和2)选自包括乙酰胆碱酯酶抑制剂,GABA门控氯化物通道拮抗剂,钠通道调节剂,烟碱乙酰胆碱受体激动剂/拮抗剂,氯化物通道激活剂,幼年激素模拟物,影响氧化磷酸化的化合物的组A中的至少一种活性化合物II ,甲壳素生物合成抑制剂,蜕皮破坏剂,MET抑制剂,电压依赖性钠通道阻滞剂,脂质合成抑制剂和描述中定义的其它化合物,具有协同有效量。 本发明进一步涉及这些混合物用于防治植物中和植物上的昆虫,蜘蛛或线虫的方法和用途,并且还用于保护被害虫侵染的植物,特别是用于保护种子。
    • 9. 发明申请
    • Pesticidal Mixtures
    • US20090305886A1
    • 2009-12-10
    • US12297338
    • 2007-04-18
    • Jürgen LangewaldHenry Van Tuyl CotterDeborah L. CulbertsonHassan Oloumi-Sadeghi
    • Jürgen LangewaldHenry Van Tuyl CotterDeborah L. CulbertsonHassan Oloumi-Sadeghi
    • A01N25/26A01N43/66A01N33/18A01P15/00
    • A01N37/34A01N47/02A01N43/22A01N43/88A01N51/00A01N63/00A01N47/30A01N2300/00
    • Pesticidal mixtures comprising, as active components, 1) a malonodinitrile compound selected from compounds I-1 to I-8 CF2HCF2CF2CF2CH2C(CN)2CH2CH2CF3 (compound I-1; name: 2-(2,2,3,3,4,4,5,5-octofluoro-pentyl)-2-(3,3,3-trifluoro-propyl)-malononitrile); CF3(CH2)2C(CN)2CH2(CF2)5CF2H (compound I-2; name: 2-(2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoro-heptyl)-2-(3,3,3-trifluoro-propyl)-malononitrile); CF3(CH2)2C(CN)2(CH2)2C(CF3)2F (compound I-3; name: 2-(3,4,4,4-tetrafluoro-3-trifluoromethyl-butyl)-2-(3,3,3-trifluoro-propyl)-malononitrile); CF3(CH2)2C(CN)2(CH2)2(CF2)3CF3 (compound I-4; name: 2-(3,3,4,4,5,5,6,6,6-nonafluoro-hexyl)-2-(3,3,3-trifluoro-propyl)-malononitrile); CF2H(CF2)3CH2C(CN)2CH2(CF2)3CF2H (compound I-5; name: 2,2-bis-(2,2,3,3,4,4,5,5-octafluoro-pentyl)-malononitrile); CF3(CH2)2C(CN)2CH2(CF2)3CF3 (compound I-6; name: 2-(2,2,3,3,4,4,5,5,5-nonafluoro-pentyl)-2-(3,3,3-trifluoro-propyl)-malononitrile); CF3(CF2)2CH2C(CN)2CH2(CF2)3CF2H (compound I-7; name: 2-(2,2,3,3,4,4,4-heptafluoro-butyl)-2-(2,2,3,3,4,4,5,5-octafluoro-pentyl)-malononitrile); or CF3CF2CH2C(CN)2CH2(CF2)3CF2H (compound I-8; name: 2-(2,2,3,3,4,4,5,5-octafluoro-pentyl)-2-(2,2,3,3,3-pentafluoro-propyl)-malononitrile); and 2) one or more compounds II selected from group A consisting of organo(thio)-phosphates, carbamates, pyrethroids, growth regulators, nicotinic receptor agonists/antagonists compounds, GABA antagonist compounds, macrocyclic lactone insecticides, METI I acaricides, METI II and III compounds, uncoupler compounds, oxidative phosphorylation inhibitor compounds, mixed function oxidase inhibitor compounds, sodium channel blocker compounds and others, all as defined in the description, in synergistically effective amounts, use of these mixture for combating insects, arachnids or nematodes in and on plants and for the protection of seeds, and for treating, controlling, preventing or protecting a warm-blooded animal or a fish against infestation or infection by parasites.
    • 10. 发明授权
    • Agrochemical formulations comprising co-polymers based on diisocyanates
    • 包含基于二异氰酸酯的共聚物的农药制剂
    • US09149034B2
    • 2015-10-06
    • US12515569
    • 2007-11-23
    • Yvonne DieckmannMichael IshaqueIngo MünsterLaurent PicardWolfgang KerlJürgen LangewaldKlaus KreuzHarald KöhleFelix Christian Görth
    • Yvonne DieckmannMichael IshaqueIngo MünsterLaurent PicardWolfgang KerlJürgen LangewaldKlaus KreuzHarald KöhleFelix Christian Görth
    • A01N47/28A01C1/06A01N37/18A01N25/10
    • A01N25/10
    • The present invention comprises formulations comprising at least one pesticide and at least one block copolymer of formula (I) wherein Ra is branched or linear C6-C24 alkyl, C3-C8 cycloalkyl, C3-C8 cycloalkyl substituted with C1-C6 alkyl, phenyl, phenyl substituted with C1-C6 alkyl, benzyl, benzyl substituted with C1-C6 alkyl, C4-C6 alkyl substituted with C4-C12 alkoxy or C1-C4 alkyl substituted with di (C1-C4 alkyl) amino; Rb is derived from a diisocyanate and Rc is a compound of formula II (R1)n—X—(CHR2CH2O)w—(CHR3CH2O)χ—(CHR4(CH2)yO)z— (II), in which R1 is hydrogen, or branched or linear, saturated or unsaturated C1-40-alkyl; R2, R3, R4 independently of one another are hydrogen or C1-4-alkyl; w, x, z independently of one another correspond to a value of from 0 to 300; y corresponds to a value of from 1 to 20; X is N or O, where n=1 if X=O, or n=2 if X=N; and the total of w, x and z amounts to at least 1; methods of combating harmful insects and/or phytopathogenic fungi, a method of controlling undesired vegetation and methods of improving the health of plants based on the afore-mentioned formulations.
    • 本发明包括包含至少一种农药和至少一种式(I)的嵌段共聚物的制剂,其中R a是支链或直链的C 6 -C 24烷基,C 3 -C 8环烷基,被C 1 -C 6烷基取代的C 3 -C 8环烷基,苯基, 被C 1 -C 6烷基取代的苯基,被C 1 -C 6烷基取代的苄基,被C 4 -C 12烷氧基取代的C 1 -C 6烷基或被二(C 1 -C 4烷基)氨基取代的C 1 -C 4烷基; Rb衍生自二异氰酸酯,Rc是式II(R1)n-X-(CHR2CH2O)w-(CHR3CH2O)χ-(CHR4(CH2)yO)z-(Ⅱ)的化合物,其中R1是氢, 或支链或直链,饱和或不饱和的C 1-40 - 烷基; R 2,R 3,R 4彼此独立地是氢或C 1-4 - 烷基; w,x,z彼此独立地对应于0至300的值; y对应于1至20的值; X是N或O,如果X = O,其中n = 1,如果X = N,则n = 2; w,x和z的总和至少为1; 防治有害昆虫和/或植物病原真菌的方法,根据上述制剂控制不需要的植物的方法和改善植物健康的方法。