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1. 发明申请

US20100121374A1 SHEATHLESS EMBOLIC PROTECTION SYSTEM 有权
标题翻译：无缝嵌入式保护系统
公开(公告)号：US20100121374A1
公开(公告)日：2010-05-13
申请号：US12689166
申请日：2010-01-18
申请人： William J. Boyle , Richard S. Stack
发明人： William J. Boyle , Richard S. Stack
IPC分类号： A61F2/01
CPC分类号： A61F2/013 , A61F2002/015 , A61F2002/018 , A61F2230/0006 , A61F2230/008
摘要： A system for enabling the insertion and removal of an embolic protection device, for capturing and retaining embolic debris which may be created during the performance of a therapeutic interventional procedure in a stenosed or occluded region of a blood vessel. The system, in an embodiment thereof, enables the device to be compressed for insertion thereof through a patient's vasculature so as to cross the stenosis in a low profile, and to enable release of compression thereof for expansion and deployment of the device at a location distal to the interventional procedure site.
摘要翻译：一种能够插入和移除栓塞保护装置的系统，用于捕获和保留在血管的狭窄或阻塞区域中执行治疗介入手术期间可产生的栓塞碎片。该系统在其一个实施例中使得该装置能够被压缩以便通过患者的脉管系统插入，以便以低轮廓的方式穿过狭窄，并且能够释放其压缩以在远端的位置处扩张和展开该装置到介入手术部位。

2. 发明授权

US07217255B2 Embolic protection devices 有权
标题翻译：栓塞保护装置
公开(公告)号：US07217255B2
公开(公告)日：2007-05-15
申请号：US10386071
申请日：2003-03-10
申请人： William J. Boyle , Andy E. Denison , Benjamin C. Huter , Scott J. Huter , Richard S. Stack , Kent C. B. Stalker , Christopher Tarapata , John D. Whitfield
发明人： William J. Boyle , Andy E. Denison , Benjamin C. Huter , Scott J. Huter , Richard S. Stack , Kent C. B. Stalker , Christopher Tarapata , John D. Whitfield
IPC分类号： A61M29/00
CPC分类号： A61F2/013 , A61F2002/011 , A61F2002/015 , A61F2002/018 , A61F2230/0006 , A61F2230/0067 , A61F2230/008
摘要： An embolic protection device for use in a blood vessel when an interventional procedure is being performed in a stenosed or occluded region to capture any embolic material which may be created and released into the bloodstream during the procedure. The device includes a filtering assembly having a self-expanding strut assembly and a filter element attached thereto. In one embodiment, the filtering assembly is attached to the distal end of a guide wire and is deployed within the patient's vasculature as the guide wire is manipulated into the area of treatment. A restraining sheath placed over the filtering assembly in a coaxial arrangement maintains the filtering assembly in its collapsed position until it is ready to be deployed by the physician. Thereafter, the sheath can be retracted to expose the filtering assembly which will then self-expand within the patient's vasculature. Interventional devices can be delivered over the guide wire and any embolic debris created during the interventional procedure and released into the blood stream will enter the filtering assembly and be captured therein. Other embodiments include filtering assemblies attached to an outer tubular member and inner shaft member which apply axial force to the distal ends of the assembly to either expand or contract the struts as needed.
摘要翻译：一种用于血管中的栓塞保护装置，当在狭窄或闭塞区域进行介入手术以捕获可能在手术期间产生和释放到血流中的任何栓塞物质。该装置包括具有自扩张支柱组件和附接到其上的过滤元件的过滤组件。在一个实施例中，过滤组件附接到导丝的远端，并且当导丝被操纵进入治疗区域时，其被布置在患者的脉管系统内。以同轴布置放置在过滤组件上方的限制护套将过滤组件保持在其收缩位置，直到其准备好由医师部署。此后，护套可缩回以露出过滤组件，然后过滤组件将在患者的脉管系统内自我扩张。介入装置可以在导丝上传送，并且在介入手术期间产生的并释放到血流中的任何栓塞碎片将进入过滤组件并被捕获在其中。其他实施例包括附接到外部管状构件和内部轴构件的过滤构件，其向组件的远端施加轴向力，以根据需要来扩展或收缩支柱。

3. 发明授权

US06540722B1 Embolic protection devices 有权
标题翻译：栓塞保护装置
公开(公告)号：US06540722B1
公开(公告)日：2003-04-01
申请号：US09490319
申请日：2000-01-24
申请人： William J. Boyle , Andy E. Denison , Benjamin C. Huter , Scott J. Huter , Richard S. Stack , Kent C. B. Stalker , Christopher Tarapata , John D. Whitfield
发明人： William J. Boyle , Andy E. Denison , Benjamin C. Huter , Scott J. Huter , Richard S. Stack , Kent C. B. Stalker , Christopher Tarapata , John D. Whitfield
IPC分类号： A61M2900
CPC分类号： A61F2/013 , A61F2002/011 , A61F2002/015 , A61F2002/018 , A61F2230/0006 , A61F2230/0067 , A61F2230/008
摘要： An embolic protection device for use in a blood vessel when an interventional procedure is being performed in a stenosed or occluded region to capture any embolic material which may be created and released into the bloodstream during the procedure. The device includes a filtering assembly having a self-expanding strut assembly and a filter element attached thereto. In one embodiment, the filtering assembly is attached to the distal end of a guide wire and is deployed within the patient's vasculature as the guide wire is manipulated into the area of treatment. A restraining sheath placed over the filtering assembly in a coaxial arrangement maintains the filtering assembly in its collapsed position until it is ready to be deployed by the physician. Thereafter, the sheath can be retracted to expose the filtering assembly which will then self-expand within the patient's vasculature. Interventional devices can be delivered over the guide wire and any embolic debris created during the interventional procedure and released into the blood stream will enter the filtering assembly and be captured therein. Other embodiments include filtering assemblies attached to an outer tubular member and inner shaft member which apply axial force to the distal ends of the assembly to either expand or contract the struts as needed.
摘要翻译：一种用于血管中的栓塞保护装置，当在狭窄或闭塞区域进行介入手术以捕获可能在手术期间产生和释放到血流中的任何栓塞物质。该装置包括具有自扩张支柱组件和附接到其上的过滤元件的过滤组件。在一个实施例中，过滤组件附接到导丝的远端，并且当导丝被操纵进入治疗区域时，其被布置在患者的脉管系统内。以同轴布置放置在过滤组件上方的限制护套将过滤组件保持在其收缩位置，直到其准备好由医师部署。此后，护套可缩回以露出过滤组件，然后过滤组件将在患者的脉管系统内自我扩张。介入装置可以在导丝上传送，并且在介入手术期间产生的并释放到血流中的任何栓塞碎片将进入过滤组件并被捕获在其中。其他实施例包括附接到外部管状构件和内部轴构件的过滤构件，其向组件的远端施加轴向力，以根据需要来扩展或收缩支柱。

4. 发明授权

US07662166B2 Sheathless embolic protection system 失效
标题翻译：无鞘栓塞保护系统
公开(公告)号：US07662166B2
公开(公告)日：2010-02-16
申请号：US11352713
申请日：2006-02-13
申请人： William J. Boyle , Richard S. Stack
发明人： William J. Boyle , Richard S. Stack
IPC分类号： A61M29/00
CPC分类号： A61F2/013 , A61F2002/015 , A61F2002/018 , A61F2230/0006 , A61F2230/008
摘要： A system for enabling the insertion and removal of an embolic protection device, for capturing and retaining embolic debris which may be created during the performance of a therapeutic interventional procedure in a stenosed or occluded region of a blood vessel. The system, in an embodiment thereof, enables the device to be compressed for insertion thereof through a patient's vasculature so as to cross the stenosis in a low profile, and to enable release of compression thereof for expansion and deployment of the device at a location distal to the interventional procedure site.
摘要翻译：一种能够插入和移除栓塞保护装置的系统，用于捕获和保留在血管的狭窄或阻塞区域中执行治疗介入手术期间可产生的栓塞碎片。该系统在其一个实施例中使得该装置能够被压缩以便通过患者的脉管系统插入，以便以低轮廓的方式穿过狭窄，并且能够释放其压缩以在远端的位置处扩张和展开该装置到介入手术部位。

5. 发明授权

US07018393B1 Sheathless embolic protection system 失效
标题翻译：无鞘栓塞保护系统
公开(公告)号：US07018393B1
公开(公告)日：2006-03-28
申请号：US09945152
申请日：2001-08-31
申请人： William J. Boyle , Richard S. Stack
发明人： William J. Boyle , Richard S. Stack
IPC分类号： A61M29/00
CPC分类号： A61F2/013 , A61F2002/015 , A61F2002/018 , A61F2230/0006 , A61F2230/008
摘要： A system for enabling the insertion and removal of an embolic protection device, for capturing and retaining embolic debris which may be created during the performance of a therapeutic interventional procedure in a stenosed or occluded region of a blood vessel. The system, in an embodiment thereof, enables the device to be compressed for insertion thereof through a patient's vasculature so as to cross the stenosis in a low profile, and to enable release of compression thereof for expansion and deployment of the device at a location distal to the interventional procedure site.
摘要翻译：一种能够插入和移除栓塞保护装置的系统，用于捕获和保留在血管的狭窄或阻塞区域中执行治疗介入手术期间可产生的栓塞碎片。该系统在其一个实施例中使得该装置能够被压缩以便通过患者的脉管系统插入，以便以低轮廓的方式穿过狭窄，并且能够释放其压缩以在远端的位置处扩张和展开该装置到介入手术部位。

6. 发明授权

US06264671B1 Stent delivery catheter and method of use 有权
标题翻译：支架输送导管及使用方法
公开(公告)号：US06264671B1
公开(公告)日：2001-07-24
申请号：US09439692
申请日：1999-11-15
申请人： Richard S. Stack , Udayan Patel , William J. Boyle , Kent C. B. Stalker , Paul F. Muller
发明人： Richard S. Stack , Udayan Patel , William J. Boyle , Kent C. B. Stalker , Paul F. Muller
IPC分类号： A61M2900
CPC分类号： A61F2/966 , A61F2/95 , A61F2/958
摘要： A deformable sheath is attached to a catheter and introduced intravascularly to be expanded against an arterial wall and entrap plaque therebetween. A stent is subsequently deployed within the expanded sheath and the sheath is then withdrawn from within the vasculature to leave the stent expanded against the arterial wall with the plaque entrapped therebetween.
摘要翻译：可变形护套附着在导管上，血管内引入以相对于动脉壁扩张并在其间夹带斑块。随后将支架部署在扩张的护套内，然后从脉管系统中撤出护套，以使支架膨胀抵靠动脉壁，其间夹有斑块。

7. 发明授权

US07931666B2 Sheathless embolic protection system 有权
标题翻译：无鞘栓塞保护系统
公开(公告)号：US07931666B2
公开(公告)日：2011-04-26
申请号：US12689166
申请日：2010-01-18
申请人： William J. Boyle , Richard S. Stack
发明人： William J. Boyle , Richard S. Stack
IPC分类号： A61M29/00
CPC分类号： A61F2/013 , A61F2002/015 , A61F2002/018 , A61F2230/0006 , A61F2230/008
摘要： A system for enabling the insertion and removal of an embolic protection device, for capturing and retaining embolic debris which may be created during the performance of a therapeutic interventional procedure in a stenosed or occluded region of a blood vessel. The system, in an embodiment thereof, enables the device to be compressed for insertion thereof through a patient's vasculature so as to cross the stenosis in a low profile, and to enable release of compression thereof for expansion and deployment of the device at a location distal to the interventional procedure site.
摘要翻译：一种能够插入和移除栓塞保护装置的系统，用于捕获和保留在血管的狭窄或阻塞区域中执行治疗介入手术期间可产生的栓塞碎片。该系统在其一个实施例中使得该装置能够被压缩以便通过患者的脉管系统插入，以便以低轮廓的方式穿过狭窄，并且能够释放其压缩以在远端的位置处扩张和展开该装置到介入手术部位。

8. 发明申请

US20100049305A1 CONVERTIBLE DELIVERY SYSTEMS FOR MEDICAL DEVICES 审中-公开
标题翻译：医疗设备可交换系统
公开(公告)号：US20100049305A1
公开(公告)日：2010-02-25
申请号：US12545602
申请日：2009-08-21
申请人： William J. Boyle , Benjamin C. Huter , John E. Papp , Jack Sahakian , Richard S. Stack
发明人： William J. Boyle , Benjamin C. Huter , John E. Papp , Jack Sahakian , Richard S. Stack
IPC分类号： A61F2/00
CPC分类号： A61M25/0668 , A61M2025/0681
摘要： A delivery system for a medical device or other devices to be deployed within a biological body including a sheath having a longitudinal joint. The joint can be either resealable or non-resealable. The joint remains intact during delivery of the medical device, thereby facilitating accurate delivery of the medical device. During removal of the sheath, the joint is separated, thereby permitting the sheath to be peeled from the medical device while maintaining the position of the device. The delivery system allows a single operator to deploy the medical device and remove the sheath.
摘要翻译：用于医疗装置或其他装置的递送系统，其将部署在包括具有纵向接头的护套的生物体内。接头可以重新密封或不可重新密封。在医疗装置的输送期间关节保持完整，从而有助于医疗装置的准确输送。在去除护套期间，接头被分离，从而允许护套在保持装置的位置的同时从医疗装置剥离。输送系统允许单个操作者部署医疗装置并移除护套。

9. 发明授权

US06645223B2 Deployment and recovery control systems for embolic protection devices 有权
公开(公告)号：US06645223B2
公开(公告)日：2003-11-11
申请号：US09845758
申请日：2001-04-30
申请人： William J. Boyle , Benjamin C. Huter , Charles R. Peterson , Donald E. Schwarten , Richard S. Stack
发明人： William J. Boyle , Benjamin C. Huter , Charles R. Peterson , Donald E. Schwarten , Richard S. Stack
IPC分类号： A61M2900
CPC分类号： A61F2/95 , A61F2/013 , A61F2002/018 , A61F2002/9517 , A61F2230/0006 , A61F2230/0067 , A61M25/09 , A61M2025/09116
摘要： A deployment control system provides controlled deployment of an embolic protection device which may include a guide wire, an expandable filter attached to the guide wire near its distal end, and a restraining sheath that maintains the expanded filter in a collapsed position. The deployment control system includes a torque control device which allows the physician to torque the guide wire into the patient's anatomy and a mechanism for preventing the guide wire from buckling as the restraining sheath is being retracted to deploy the expandable filter. A recovery control system for recovering the embolic protection device includes an inner catheter which extends within a lumen of an outer recovery sheath in a coaxial arrangement. A distal portion of the inner catheter extends beyond another recovery sheath during advancement of the recovery system into the vasculature. The recovery sheath can be advanced over the inner catheter to collapse the expandable filter. The proximal ends of the inner catheter and recovery sheath include handle portions having snap mechanisms which hold the components together as the recovery system is being advanced into the patient's vasculature.

10. 发明授权

US6139511A Guidewire with variable coil configuration 失效
标题翻译：导丝可变线圈配置
公开(公告)号：US6139511A
公开(公告)日：2000-10-31
申请号：US106918
申请日：1998-06-29
申请人： Scott J. Huter , William J. Boyle , Richard S. Stack
发明人： Scott J. Huter , William J. Boyle , Richard S. Stack
IPC分类号： A61B5/00 , A61M25/09
CPC分类号： A61M25/09 , A61M2025/09083
摘要： The present invention is directed to a guidewire having an elongate core member with a proximal section and a distal section. The distal section has at least one tapered segment, wherein the elongate core member tapers distally to a reduced diameter. Preferably, the tapered segments of the distal section of the elongate core member are marked with radiopaque markers to indicate where a tapered segment begins or ends. A proximal coil having a rectangular cross section and at least one distal coil having a round cross section are disposed around at least a portion of the distal section of the elongate core member. The proximal end of the proximal coil is attached to the distal section of the elongate core member. The distal coils can be made of a material that is radiopaque or non-radiopaque. If one of the distal coils is radiopaque, it may be made from a radiopaque material or it may be made of a hollow tube of non-radiopaque material that is filled with material that is at least partially radiopaque. The proximal end of the distal most coil is attached to the distal end of the proximal coil, and the distal end of the distal most coil is attached to the distal section of the elongate core member.
摘要翻译：本发明涉及一种具有细长芯部件的导丝，其具有近端部分和远端部分。远侧部分具有至少一个锥形部分，其中细长芯部件向远端逐渐变细直径减小。优选地，细长芯部件的远端部分的锥形部分用不透射线的标记标记，以指示锥形部分开始或结束的位置。具有矩形截面的近端线圈和具有圆形横截面的至少一个远端线圈设置在细长芯部件的远端部分的至少一部分周围。近端线圈的近端附接到细长芯构件的远端部分。远侧线圈可以由不透射线或非不透射线的材料制成。如果远端线圈之一是不透射线的，则其可以由不透射线材料制成，或者其可以由填充有至少部分不透射线的材料的非不透射线材料的中空管制成。最远端线圈的近端附接到近端线圈的远端，并且最远端线圈的远端附接到细长芯构件的远端部分。

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