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1. 发明授权

US08442656B2 Cardiac lead having implantable stiffening structures for fixation 有权
标题翻译：心脏导联具有可植入的硬化结构用于固定
公开(公告)号：US08442656B2
公开(公告)日：2013-05-14
申请号：US11422014
申请日：2006-06-02
申请人： Bruce A. Tockman , Brian D. Soltis , Eric T. Johnson , Kent C. B. Stalker , Peter J. D'aquanni , Paul E. Zarembo
发明人： Bruce A. Tockman , Brian D. Soltis , Eric T. Johnson , Kent C. B. Stalker , Peter J. D'aquanni , Paul E. Zarembo
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61N1/0573 , A61N2001/0585
摘要： A cardiac lead adapted for fixation at least partially within a cardiac vessel. The lead includes, in one embodiment, an elongate lead body defining a proximal region and a distal region including a distal end region having at least one electrode and a distal tip. The distal end region is configured such that the electrode and the distal tip can be implanted in the cardiac vessel. Stiffening structures in the distal region of the lead are adapted to stiffen selected portions of the lead for fixation of the electrode within the cardiac vessel. In some embodiments, the stiffening structures include an implantable member adapted to be implanted in a lumen of the lead. In other embodiments, the stiffening structures include a sheath adapted to be deployed over the lead body. In still other embodiments, the stiffening structures are integral to the lead and/or the lead body.
摘要翻译：适于至少部分地固定在心脏血管内的心脏引线。在一个实施例中，引线包括限定近端区域的细长引线体和包括具有至少一个电极和远端尖端的远端区域的远侧区域。远端区域被构造成使得电极和远端尖端可以植入心脏血管。铅的远端区域中的加强结构适于加强导线的选定部分，以将电极固定在心脏血管内。在一些实施例中，加强结构包括适于植入在引导管腔中的可植入部件。在其他实施例中，加强结构包括适于部署在引线主体上的护套。在其他实施例中，加强结构与引线和/或引线主体成一体。

2. 发明申请

US20070282413A1 CARDIAC LEAD HAVING STIFFENING STRUCTURES FOR FIXATION 审中-公开
标题翻译：具有固定结构的CARDIAC引线
公开(公告)号：US20070282413A1
公开(公告)日：2007-12-06
申请号：US11422012
申请日：2006-06-02
申请人： Bruce A. Tockman , Brian D. Soltis , Eric T. Johnson , Kent C. B. Stalker , Peter J. D' aquanni , Paul E. Zarembo
发明人： Bruce A. Tockman , Brian D. Soltis , Eric T. Johnson , Kent C. B. Stalker , Peter J. D' aquanni , Paul E. Zarembo
IPC分类号： A61N1/05
CPC分类号： A61N1/057 , A61N2001/0585
摘要： A cardiac lead adapted for fixation at least partially within a cardiac vessel. The lead includes, in one embodiment, an elongate lead body defining a proximal region and a distal region including a distal end region having at least one electrode and a distal tip. The distal end region is configured such that the electrode and the distal tip can be implanted in the cardiac vessel. Stiffening structures in the distal region of the lead are adapted to stiffen selected portions of the lead for fixation of the electrode within the cardiac vessel. In some embodiments, the stiffening structures include an implantable member adapted to be implanted in a lumen of the lead. In other embodiments, the stiffening structures include a sheath adapted to be deployed over the lead body. In still other embodiments, the stiffening structures are integral to the lead and/or the lead body.
摘要翻译：适于至少部分地固定在心脏血管内的心脏引线。在一个实施例中，引线包括限定近端区域的细长引线体和包括具有至少一个电极和远端尖端的远端区域的远侧区域。远端区域被构造成使得电极和远端尖端可以植入心脏血管。铅的远端区域中的加强结构适于加强导线的选定部分，以将电极固定在心脏血管内。在一些实施例中，加强结构包括适于植入在引导管腔中的可植入部件。在其他实施例中，加强结构包括适于部署在引线主体上的护套。在其他实施例中，加强结构与引线和/或引线主体成一体。

3. 发明授权

US07252675B2 Embolic filtering devices 有权
标题翻译：栓塞过滤装置
公开(公告)号：US07252675B2
公开(公告)日：2007-08-07
申请号：US10260710
申请日：2002-09-30
申请人： Andy E. Denison , William J. Harrison , Benjamin C. Huter , Scott J. Huter , John E. Papp , Steven T. Saville , Kent C. B. Stalker
发明人： Andy E. Denison , William J. Harrison , Benjamin C. Huter , Scott J. Huter , John E. Papp , Steven T. Saville , Kent C. B. Stalker
IPC分类号： A61M29/00
CPC分类号： A61F2/013 , A61F2002/015 , A61F2002/018 , A61F2230/0006 , A61F2230/008
摘要： An expandable frame for an embolic filtering device used to capture embolic debris in a body vessel includes a first half frame having a first control arm connected to a second control arm by a partial loop and a second half frame having a first control arm connected to a second control arm by a partial loop. The partial loops cooperatively form a composite loop for attachment of a filtering element which will expand in the body vessel to capture embolic debris entrained in the fluid of the vessel. The lengths and positioning of the first and second control arms of each half frame can be varied to create an expandable frame which conforms to the size and shape of the body vessel in which the filtering device is deployed. Additionally, the radius of the partial loops, along with the length of the arc of the partial loops, can be varied on each of the frames to create a composite filtering assembly that can easily adapt to the size and shape of the body vessel. Additionally, the control arms of the half frames can be disposed either proximally or distally of the composite loop to create a distinct filtering structure.
摘要翻译：用于捕获身体血管中的栓塞碎片的栓塞过滤装置的可膨胀框架包括：第一半框架，具有通过部分回路连接到第二控制臂的第一控制臂，以及具有连接到第二控制臂的第二控制臂的第二半框架第二控制臂通过部分回路。部分回路协同地形成用于附接过滤元件的复合回路，该过滤元件将在体内容器中膨胀以捕获携带在血管流体中的栓塞碎片。可以改变每个半框架的第一和第二控制臂的长度和定位，以便产生符合过滤装置展开的身体容器的尺寸和形状的可扩张框架。此外，部分回路的半径以及部分回路的圆弧的长度可以在每个框架上变化以产生可以容易地适应身体血管的尺寸和形状的复合过滤组件。此外，半框架的控制臂可以在复合环路的近侧或远端设置，以产生不同的过滤结构。

4. 发明授权

US06652576B1 Variable stiffness stent 有权
标题翻译：可变刚度支架
公开(公告)号：US06652576B1
公开(公告)日：2003-11-25
申请号：US09590307
申请日：2000-06-07
申请人： Kent C. B. Stalker
发明人： Kent C. B. Stalker
IPC分类号： A61F206
CPC分类号： A61F2/915 , A61F2/91 , A61F2002/91516 , A61F2002/91525 , A61F2002/91533 , A61F2002/91575 , A61F2250/0018
摘要： A stent having a structure differentiated in terms of its stiffness. Such differentiation is achieved with the use of a superelastic material that transitions between a relatively soft and malleable phase to a stiffer phase at a transition temperature that is adjustable. By differentially adjusting the transition temperature of different portions of the stent, a differentiation of the stiffness of the structure is achieved upon the stent being subjected to body temperature.
摘要翻译：具有在其刚度方面不同的结构的支架。这种分化是通过使用在可调节的转变温度下在相对柔软和可延展的相之间转变成更硬相的超弹性材料来实现的。通过差异调节支架的不同部分的转变温度，在支架经受体温后实现结构刚度的分化。

5. 发明授权

US06264671B1 Stent delivery catheter and method of use 有权
标题翻译：支架输送导管及使用方法
公开(公告)号：US06264671B1
公开(公告)日：2001-07-24
申请号：US09439692
申请日：1999-11-15
申请人： Richard S. Stack , Udayan Patel , William J. Boyle , Kent C. B. Stalker , Paul F. Muller
发明人： Richard S. Stack , Udayan Patel , William J. Boyle , Kent C. B. Stalker , Paul F. Muller
IPC分类号： A61M2900
CPC分类号： A61F2/966 , A61F2/95 , A61F2/958
摘要： A deformable sheath is attached to a catheter and introduced intravascularly to be expanded against an arterial wall and entrap plaque therebetween. A stent is subsequently deployed within the expanded sheath and the sheath is then withdrawn from within the vasculature to leave the stent expanded against the arterial wall with the plaque entrapped therebetween.
摘要翻译：可变形护套附着在导管上，血管内引入以相对于动脉壁扩张并在其间夹带斑块。随后将支架部署在扩张的护套内，然后从脉管系统中撤出护套，以使支架膨胀抵靠动脉壁，其间夹有斑块。

6. 发明授权

US08672991B2 Delivery and recovery sheaths for medical devices 失效
标题翻译：用于医疗器械的输送和恢复护套
公开(公告)号：US08672991B2
公开(公告)日：2014-03-18
申请号：US12724140
申请日：2010-03-15
申请人： William J. Boyle , Andy E. Denison , Benjamin C. Huter , Scott J. Huter , John E. Papp , Charles R. Peterson , Kent C. B. Stalker
发明人： William J. Boyle , Andy E. Denison , Benjamin C. Huter , Scott J. Huter , John E. Papp , Charles R. Peterson , Kent C. B. Stalker
IPC分类号： A61F2/06
CPC分类号： A61F2/013 , A61F2/95 , A61F2002/011 , A61F2002/018 , A61F2230/0006 , A61F2230/008
摘要： A deployment control system provides controlled deployment of an embolic protection device which may include a guide wire, an expandable filter attached to the guide wire near its distal end, and a restraining sheath that maintains the expanded filter in a collapsed position. The deployment control system includes a torque control device which allows the physician to torque the guide wire into the patient's anatomy and a mechanism for preventing the guide wire from buckling as the restraining sheath is being retracted to deploy the expandable filter. A recovery control system for recovering the embolic protection device includes an inner catheter which extends within a lumen of an outer recovery sheath in a coaxial arrangement. A distal portion of the inner catheter extends beyond another recovery sheath during advancement of the recovery system into the vasculature. The recovery sheath can be advanced over the inner catheter to collapse the expandable filter. The proximal ends of the inner catheter and recovery sheath include handle portions having snap mechanisms which hold the components together as the recovery system is being advanced into the patient's vasculature.
摘要翻译：部署控制系统提供栓塞保护装置的可控部署，该栓塞保护装置可以包括引导线，在其远端附近附接到导丝的可扩张过滤器，以及将扩张过滤器保持在折叠位置的限制护套。部署控制系统包括扭矩控制装置，该扭矩控制装置允许医师将导丝扭转到患者的解剖结构中，以及用于防止导线在收缩护套以展开可膨胀过滤器时弯曲的机构。用于回收栓塞保护装置的恢复控制系统包括在同轴布置中在外部恢复护套的内腔内延伸的内导管。在将回收系统推进脉管系统期间，内导管的远端部分延伸超过另一恢复护套。恢复护套可以在内导管上推进以使可膨胀过滤器折叠。内导管和恢复护套的近端包括手柄部分，其具有卡扣机构，当回收系统进入患者的脉管系统时，该部件将部件保持在一起。

7. 发明授权

US08052731B2 Medical electrical lead with expandable fixation features 失效
标题翻译：具有可扩展固定功能的医用电线
公开(公告)号：US08052731B2
公开(公告)日：2011-11-08
申请号：US11422000
申请日：2006-06-02
申请人： Brian D. Soltis , Bruce A. Tockman , Kent C. B. Stalker , Eric T. Johnson , Peter J. D'Aquanni
发明人： Brian D. Soltis , Bruce A. Tockman , Kent C. B. Stalker , Eric T. Johnson , Peter J. D'Aquanni
IPC分类号： A61F2/06 , A61N1/05
CPC分类号： A61N1/057 , A61B18/1492 , A61B2017/00243
摘要： A medical electrical lead adapted to be at least partially implanted in a cardiac vessel includes a fixation feature operable to change from an undeployed configuration to a deployed configuration in which the fixation feature is adapted to engage an inner surface of the cardiac vessel. A tendon is disposed within a lumen of the lead and is operatively connected to the fixation feature and adapted to cause the fixation feature to change from the undeployed configuration to the deployed configuration for acute and/or chronic fixation of the lead. In one embodiment, the fixation feature includes a deflectable region of the lead which in the deployed configuration causes a surface of the lead body to engage the inner surface of the cardiac vessel. In another embodiment, the fixation feature includes a radially expandable structure for engaging the inner surface of the vessel in the deployed configuration.
摘要翻译：适于至少部分地植入心脏血管的医用电线包括固定特征，其可操作以从未部署的构型改变为展开构造，其中固定特征适于接合心脏血管的内表面。腱设置在引导件的内腔中并且可操作地连接到固定特征并且适于使固定特征从未部署的构型改变为用于引导的急性和/或慢性固定的展开配置。在一个实施例中，固定特征包括引线的可偏转区域，其在展开构型中引起引线主体的表面接合心脏血管的内表面。在另一个实施例中，固定特征包括用于在展开构型中接合容器内表面的径向可扩展结构。

8. 发明授权

US07765015B2 Lead with inflatable fixation mechanism 失效
标题翻译：带充气固定机构
公开(公告)号：US07765015B2
公开(公告)日：2010-07-27
申请号：US11622810
申请日：2007-01-12
申请人： Eric T. Johnson , Brian D. Soltis , Bruce A. Tockman , Peter J. D'aquanni , Kent C. B. Stalker , Gayla A. Smith
发明人： Eric T. Johnson , Brian D. Soltis , Bruce A. Tockman , Peter J. D'aquanni , Kent C. B. Stalker , Gayla A. Smith
IPC分类号： A61N1/05
CPC分类号： A61N1/057 , A61M25/04 , A61M25/10 , A61N2001/0585
摘要： A medical electrical lead configured for use in stimulating the left side of the heart (i.e., the left ventricle). In one embodiment, the lead includes an elongate lead body including an inner surface. An inflatable member is disposed on the outer surface of the body between its proximal and distal ends, the inflatable member being adapted when inflated to impart a radial force on and frictionally engage a surface of the coronary sinus or coronary vein for fixation of the distal end of the lead therein. The lead further includes a conductive member extending from the proximal end toward the distal end, and an inner insulating layer positioned between the conductive member and the inner surface of the body. Separation between the inner insulating layer and the inner surface of the body defines an inflation lumen in fluid communication with the inflatable member.
摘要翻译：构造成用于刺激心脏左侧（即，左心室）的医用电线。在一个实施例中，引线包括包括内表面的细长引线主体。可膨胀构件设置在身体的近端和远端之间的外表面上，所述可膨胀构件适于在膨胀时赋予径向力并摩擦地接合冠状窦或冠状静脉的表面以固定远端的铅。引线还包括从近端朝向远端延伸的导电构件，以及位于导电构件和主体内表面之间的内绝缘层。内绝缘层和本体内表面之间的分离限定了与可膨胀构件流体连通的膨胀腔。

9. 发明授权

US07632303B1 Variable stiffness medical devices 失效
标题翻译：可变刚度医疗设备
公开(公告)号：US07632303B1
公开(公告)日：2009-12-15
申请号：US10152150
申请日：2002-05-21
申请人： Kent C. B. Stalker , Masoud Molaei , John F. Boylan , Matthew J. Gillick
发明人： Kent C. B. Stalker , Masoud Molaei , John F. Boylan , Matthew J. Gillick
IPC分类号： A61F2/06
CPC分类号： A61F2/90 , A61F2/91 , A61F2/95 , A61F2002/9665 , A61F2250/0018
摘要： A medical device has a structure differentiated in terms of its stiffness or elasticity. Such stiffness differentiation is achieved through the use of superelastic or shape-memory materials which transition between a relatively malleable phase to a stiffer phase at a transition temperature which is adjustable by heat treatment. A differentiation of the stiffness of the structure forming the medical device is achieved by differentially adjusting the transition temperature of select portions of the medical device before the medical device is placed in its operational mode, usually implanted in a body at body temperature.
摘要翻译：医疗器械具有在其刚性或弹性方面不同的结构。这种刚度分化是通过使用超弹性或形状记忆材料来实现的，该材料在可通过热处理可调节的转变温度下在相对可延展的相到较硬相之间转变。形成医疗装置的结构的刚度的差异通过在将医疗装置置于其操作模式之前差异调节医疗装置的选择部分的转变温度来实现，通常在体温下植入体内。

10. 发明申请

US20080071339A1 MECHANISM FOR RELEASABLY ENGAGING AN IMPLANTABLE MEDICAL DEVICE FOR IMPLANTATION 有权
标题翻译：用于植入可植入医疗器械用于植入的机构
公开(公告)号：US20080071339A1
公开(公告)日：2008-03-20
申请号：US11855501
申请日：2007-09-14
申请人： Kent C. B. Stalker , Peter J. D'Aquanni , Eric T. Johnson
发明人： Kent C. B. Stalker , Peter J. D'Aquanni , Eric T. Johnson
IPC分类号： A61N1/05
CPC分类号： A61B5/0215 , A61B5/6876 , A61B2560/066 , A61M25/0074 , A61N1/05 , A61N2001/0578
摘要： An apparatus for releasably engaging an implantable medical device during delivery includes an elongate, tubular body having an open distal end a plurality of deflectable jaw members extending distally from the distal end of the body and terminating in distal tip portions, and an actuating member slidably disposed within the body and including a distal end portion operable to prevent inward deflection of the jaw members when positioned proximate the distal tip portions. The jaw members are adapted to releasably engage an engagement feature of the implantable medical device.
摘要翻译：一种用于在输送过程中可释放地接合植入式医疗装置的装置包括细长的管状体，其具有开放的远端，多个可偏转的钳口构件从主体的远端向远侧延伸并且终止于远侧末端部分，以及可滑动地设置的致动构件并且包括远端部分，其可操作以防止当邻近远侧末端部分定位时夹爪构件向内偏转。钳口构件适于可释放地接合可植入医疗装置的接合特征。

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