会员体验
专利管家(专利管理)
工作空间(专利管理)
风险监控(情报监控)
数据分析(专利分析)
侵权分析(诉讼无效)
联系我们
交流群
官方交流:
QQ群: 891211   
微信请扫码    >>>
现在联系顾问~
热词
    • 5. 发明申请
    • METHOD OF EVALUATING SKIN BARRIER FUNCTION, METHOD OF SCREENING MATERIAL FOR ENHANCING SKIN BARRIER FUNCTION USING THE EVALUATING METHOD, THE MATERIAL FOR ENHANCING SKIN BARRIER FUNCTION, AND COSMETIC CONTAINING THE MATERIAL FOR ENHANCING SKIN BARRIER FUNCTION
    • 评估皮肤障碍功能的方法,使用评估方法,用于增强皮肤屏障功能的材料和包含用于增强皮肤屏障功能的材料的化妆品来增强皮肤屏障功能的材料筛选方法
    • US20100068309A1
    • 2010-03-18
    • US12516483
    • 2007-12-07
    • Shohei KurodaTakuya YamamotoYuko SaekiMasumi Kurasawa
    • Shohei KurodaTakuya YamamotoYuko SaekiMasumi Kurasawa
    • A61K8/97C12Q1/02A61Q19/00
    • G01N33/5044G01N33/84
    • A method for developing an excellent material for enhancing skin barrier function, and providing a cosmetic which is developed based on the method and has excellent ability to enhance skin barrier function is described. The method evaluates skin barrier function by the steps of 1) culturing normal human epidermal cells in wells having a semipermeable membrane with two sides, in presence and absence of a test substance; 2) adding a medium not containing metal ions to a first side of the semipermeable membrane in each well and a medium containing the metal ions to a second side of the semipermeable membrane in each well, provided that the cells are adhered to the first side of the semipermeable membrane; 3) culturing the cells; 4) measuring the concentration of the metal ions in each medium; and 5) calculating permeability of the metal ions in the epidermal cell layer based on the measured concentrations of the metal ions in each media. The test substance is effective for enhancing skin barrier function when the permeability is reduced in the medium in which the test substance is added compared to the permeability in the medium in which no test substance is added. The larger the level of reduced permeability, the higher the suitability of the test substance as a material for enhancing skin barrier function.
    • 描述了开发用于增强皮肤屏障功能的优异材料的方法,并且提供了基于该方法开发并具有优异的增强皮肤屏障功能的能力的化妆品。 该方法通过以下步骤评估皮肤屏障功能:1)在存在和不存在测试物质的情况下,在具有双侧半透膜的孔中培养正常人表皮细胞; 2)在每个孔中将不含金属离子的介质加入到每个孔中的半透膜的第一侧和含有金属离子的介质到每个孔中的半透膜的第二侧,条件是细胞粘附到 半透膜; 3)培养细胞; 4)测量各介质中金属离子的浓度; 以及5)基于每个介质中测量的金属离子浓度来计算表皮细胞层中金属离子的渗透性。 当与添加试验物质的培养基中的渗透性相比,在加入被检物质的培养基中,渗透性降低时,检测物质对增强皮肤屏障功能是有效的。 渗透性降低程度越大,测试物质作为增强皮肤屏障功能的材料的适用性就越高。
    • 7. 发明申请
    • Shaft bearing retainer
    • 轴承保持架
    • US20070098312A1
    • 2007-05-03
    • US11642488
    • 2006-12-20
    • Takuya Yamamoto
    • Takuya Yamamoto
    • F16C33/41
    • F16C33/416F16C19/18
    • A retainer for holding bearings within a shaft bearing has C-shaped pockets for holding the bearings. Between the pockets are connecting portions, which are close to the openings of the pockets. The rear sides of adjacent pockets and the rear side of the connecting portion for the adjacent pockets form a concave site that is deeply gouged into the retainer. The bottom of the concave site is closer to the openings than the bottom of the pockets, thereby allowing base oil from grease in the concave site to better migrate onto the bearings and so lubricate the shaft bearing.
    • 用于在轴承内保持轴承的保持器具有用于保持轴承的C形口袋。 在这些凹穴之间是连接部分,它们靠近口袋的开口。 相邻袋的后侧和相邻袋的连接部分的后侧形成凹入的位置,该凹陷位置被深深地压入保持器中。 凹部位置的底部比凹部的底部更靠近开口,从而允许在凹部位置的润滑脂的基础油更好地迁移到轴承上,并且润滑轴承。
    • 8. 发明授权
    • Image forming apparatus including a controller for controlling an exposure of a photosensitive member for minimizing the difference in tone between areas on the photosensitive member
    • 图像形成装置包括控制器,用于控制用于最小化感光构件上的区域之间的差异的感光构件的曝光
    • US07123342B2
    • 2006-10-17
    • US10936822
    • 2004-09-09
    • Takuya Yamamoto
    • Takuya Yamamoto
    • G03B27/52G03B27/32
    • G03B27/32
    • An image forming apparatus comprises an exposure department for exposing photographic paper conveyed at a first conveying speed, a development department for developing the photographic paper, conveyed at a second conveying speed lower than the first conveying speed, after being exposed in the exposure department. In the image forming apparatus, the relationship between 1) the distance along the conveying direction from a reference area to a micro area being the target of exposure correction, both the reference area and the micro area being on the photographic paper, and 2) the difference in tone between images formed at the reference area and the micro area when the reference area and the micro area are exposed to the same amount of light in the exposure department, and the relationship between the exposure of the photographic paper and the tone of the image at the reference area are stored.
    • 图像形成装置包括曝光部,用于曝光在第一传送速度下的照相纸,用于显影相纸的显影部分,在曝光部分曝光之后以低于第一传送速度的第二传送速度传送。 在图像形成装置中,1)沿着从参考区域到微区域的传送方向的距离是曝光校正的目标,照相纸上的参考区域和微区域两者之间的关系,以及2) 当参考区域和微区域暴露于曝光部门中的相同光量时,在参考区域形成的图像与微区域之间的色调差异以及相纸的曝光与照相机的色调之间的关系 存储参考区域的图像。