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1. 发明申请

US20050283006A1 Heteroaryl-substituted pyrrole derivatives, their preparation and their therapeutic uses 审中-公开
标题翻译：杂芳基取代的吡咯衍生物，其制备及其治疗用途
公开(公告)号：US20050283006A1
公开(公告)日：2005-12-22
申请号：US10411061
申请日：2003-04-10
申请人： Tomio Kimura , Kazumasa Aoki , Akira Nakao , Shigeru Ushiyama , Takaichi Shimozato , Nobuyuki Ohkawa , Takayoshi Nagasaki , Takanori Yamazaki
发明人： Tomio Kimura , Kazumasa Aoki , Akira Nakao , Shigeru Ushiyama , Takaichi Shimozato , Nobuyuki Ohkawa , Takayoshi Nagasaki , Takanori Yamazaki
IPC分类号： C07D401/04 , C07D401/14 , C07D451/02 , C07D453/02 , C07D455/02 , C07D471/04 , C07D487/04 , C07D491/20 , C07D41/14 , C07D43/02
CPC分类号： C07D451/02 , C07D401/04 , C07D401/14 , C07D453/02 , C07D455/02 , C07D471/04 , C07D487/04
摘要： Compounds having activity against production of inflammatory cytokines of formula (I)′: A′ is pyrrole; R1′ is aryl or heteroaryl; R2′ is heteroaryl having at least one nitrogen atom; R3′ is (IIa)′, (IIb)′ or (IIc)′: m′ is 1 or 2; one of D′ and E′ is nitrogen and the other is >C(R5′)—, R5′ is hydrogen, Substituent α′ or Substituent β′; B′ is nitrogen-containing 4- to 7-membered heterocyclic; R4′ is 1 to 3 substituents from Substituent α′, Substituent β′ and Substituent γ′; R1′ and R3′ are bonded to two atoms of the pyrrole adjacent to the pyrrole atom bonded to R2′; Substituent α′: hydroxyl, nitro, cyano, halogen, alkoxy, halogeno alkoxy, alkylthio, halogeno alkylthio or —NRa′Rb′; Ra′ and Rb′ are hydrogen, alkyl, alkenyl, alkynyl, aralkyl or alkylsulfonyl, or Ra′ and Rb′ with the nitrogen atom form a heterocyclyl; Substituent β′: alkyl, alkenyl, alkynyl, aralkyl or cycloalkyl; Substituent γ′: oxo, hydroxyimino, alkoxyimino, alkylene, alkylenedioxy, alkylsulfinyl, alkylsulfonyl, aryl, aryloxy, alkylidenyl or aralkylidenyl.
摘要翻译：具有抗式产生式（I）的炎性细胞因子的化合物的化合物：A'是吡咯; R 1是芳基或杂芳基; R 2是具有至少一个氮原子的杂芳基; （IIa）'，（IIb）'或（IIc）'：m'为1或2; D'和E'之一是氮，另一个是> C（R 5'） - ，R 5'是氢，取代基α'或取代基β'; B'是含氮的4-至7-元杂环; R 4'是1至3个取代基α'，取代基β'和取代基γ'的取代基; R 1'和R 3'连接到与R 2'连接的吡咯原子相邻的吡咯的两个原子上; 取代基α'：羟基，硝基，氰基，卤素，烷氧基，卤代烷氧基，烷硫基，卤代烷硫基或-NR a R b b。 R a，O和R b'是氢，烷基，烯基，炔基，芳烷基或烷基磺酰基，或者R a'和R“ b'与氮原子形成杂环基; 取代基β'：烷基，烯基，炔基，芳烷基或环烷基; 取代基γ'：氧代，羟基亚氨基，烷氧基亚氨基，亚烷基，亚烷基二氧基，烷基亚磺酰基，烷基磺酰基，芳基，芳氧基，亚烷基或芳烷基。

2. 发明授权

US07122666B2 Heteroaryl-substituted pyrrole derivatives, their preparation and their therapeutic uses 失效
标题翻译：杂芳基取代的吡咯衍生物，其制备及其治疗用途
公开(公告)号：US07122666B2
公开(公告)日：2006-10-17
申请号：US10354648
申请日：2003-01-30
申请人： Tomio Kimura , Akira Nakao , Nobuyuki Ohkawa , Takayoshi Nagasaki , Takanori Yamazaki
发明人： Tomio Kimura , Akira Nakao , Nobuyuki Ohkawa , Takayoshi Nagasaki , Takanori Yamazaki
IPC分类号： C07D207/00 , C07D209/00
CPC分类号： C07D451/02 , C07D401/04 , C07D401/14 , C07D453/02 , C07D455/02 , C07D471/04 , C07D487/04
摘要： Compounds having activity against production of an inflammatory cytokine of formula (I)′: A′ is pyrrole; R1′ is phenyl or naphthyl; R2′ is pyridyl or pyrimidinyl; R3′ is (IIa)′, (IIb)′ or (IIc)′: m′ is 1; E′ is nitrogen; D′ is >C(R5′)—, R5′ is hydrogen, Substituent α′ or Substituent β′; B′ is nitrogen-containing 5-membered heterocyclic; R4′ is 1 to 3 substituents from Substituent α′, Substituent β′ and Substituent γ′; R1′ and R3′ are bonded to two atoms of the pyrrole adjacent to the pyrrole atom bonded to R2′; Substituent α′ is hydroxyl, nitro, cyano, halogen, alkoxy, halogeno alkoxy, alkylthio, halogeno alkylthio or —NRa′Rb′; Ra′ and Rb′ are hydrogen, alkyl, alkenyl, alkynyl, aralkyl or alkylsulfonyl, or Ra′ and Rb′ with the nitrogen atom form a heterocyclyl; Substituent β′ is alkyl, alkenyl, alkynyl, aralkyl or cycloalkyl; Substituent γ′ is oxo, hydroxyimino, alkoxyimino, alkylene, alkylenedioxy, alkylsulfinyl, alkylsulfonyl, aryl, aryloxy, alkylidenyl or aralkylidenyl.
摘要翻译：具有抗式产生式（I）的炎性细胞因子的活性化合物的化合物：A'是吡咯; R 1是苯基或萘基; R 2是吡啶基或嘧啶基; （IIa）'，（IIb）'或（IIc）'：m'为1; E'是氮; D'是> C（R 5'） - ，R 5'是氢，取代基α'或取代基β'; B'是含氮5元杂环; R 4'是1至3个取代基α'，取代基β'和取代基γ'的取代基; R 1'和R 3'连接到与R 2'连接的吡咯原子相邻的吡咯的两个原子上; 取代基α'是羟基，硝基，氰基，卤素，烷氧基，卤代烷氧基，烷硫基，卤代烷硫基或-NR a R b B。 R a，O和R b'是氢，烷基，烯基，炔基，芳烷基或烷基磺酰基，或者R a'和R“ b'与氮原子形成杂环基; 取代基β'是烷基，烯基，炔基，芳烷基或环烷基; 取代基γ'是氧代，羟基亚氨基，烷氧基亚氨基，亚烷基，亚烷基二氧基，烷基亚磺酰基，烷基磺酰基，芳基，芳氧基，亚烷基或芳亚烷基。

3. 发明授权

US09121687B2 Pinch detection device at opening/closing section, vehicle having the device, and method for detecting pinch at the opening/closing section 有权
标题翻译：打开/关闭部分的夹紧检测装置，具有该装置的车辆，以及用于检测打开/关闭部分的夹紧的方法
公开(公告)号：US09121687B2
公开(公告)日：2015-09-01
申请号：US13808312
申请日：2011-12-16
申请人： Setsuro Mori , Tsuyoshi Eguchi , Takanori Yamazaki , Toshikazu Karube
发明人： Setsuro Mori , Tsuyoshi Eguchi , Takanori Yamazaki , Toshikazu Karube
IPC分类号： G01R27/28 , G01B7/14 , E05F15/41
CPC分类号： G01B7/14 , E05F15/40 , E05F15/41 , E05Y2400/334 , E05Y2400/336 , E05Y2400/34 , E05Y2400/36 , E05Y2400/54 , E05Y2400/56 , E05Y2400/564 , E05Y2900/50 , E05Y2900/53 , E05Y2900/531 , E05Y2900/55
摘要： A pinch detection device at an opening/closing section has a very simple structure that can surely detect a pinch without faulty operation in a vehicle whose power supply voltage greatly fluctuates. The pinch detection device includes a sensor for detecting displacement of an opening/closing section of a vehicle to be opened/closed by a motor, and a time counter for counting a relative time adjusted according to a fluctuation in a power supply voltage. The pinch detection device also has a pinch detector for detecting a pinch of a foreign matter at the opening/closing section according to a change in a relative speed obtained based on a change in the displacement on a basis of the relative time.
摘要翻译：打开/关闭部分的夹紧检测装置具有非常简单的结构，其可以可靠地检测到电源电压极大波动的车辆中没有故障的操作。夹送检测装置包括用于检测由电动机打开/关闭的车辆的开闭部的位移的传感器，以及用于对根据电源电压的波动进行调整的相对时间进行计数的计时器。夹送检测装置还具有夹紧检测器，用于根据相对于相对时间的位移变化而获得的相对速度的变化来检测开闭部处的异物的夹紧。

4. 发明授权

US08668382B2 Method for evaluating life of cable insulating coating material 有权
标题翻译：电缆绝缘涂层材料寿命评估方法
公开(公告)号：US08668382B2
公开(公告)日：2014-03-11
申请号：US13396199
申请日：2012-02-14
申请人： Kyoko Honbo , Motoko Harada , Hideto Momose , Takanori Yamazaki , Daisuke Abe , Yoshiaki Nakamura
发明人： Kyoko Honbo , Motoko Harada , Hideto Momose , Takanori Yamazaki , Daisuke Abe , Yoshiaki Nakamura
IPC分类号： G01N3/60 , G01N17/00
CPC分类号： G01N25/00 , H01B3/30 , H01B7/28
摘要： Disclosed is a method for estimating, within a short time, the life of a cable insulating coating material containing an antioxidant in a suitable concentration based on the rate of decrease of the antioxidant and on the critical concentration of the antioxidant at which oxidative degradation rapidly proceeds. The method tests the coating material to examine its life, the coating material including a base polymer, and an antioxidant having a functional group suppressing an oxidative deteriorative reaction of the base polymer. The method includes performing a thermal degradation test on the coating material; determining the degradation levels and degradation rates of the coating material at two or more time points in the thermal degradation test, based on the ratio of the absorbance of the functional group of the antioxidant to the absorbance of the base polymer; and thereby evaluating the life of the coating material.
摘要翻译：公开了一种在短时间内基于抗氧化剂的降低速率和氧化降解快速进行的抗氧化剂的临界浓度估算含有抗氧化剂的电缆绝缘涂层材料的寿命的方法。该方法测试涂层材料以检查其寿命，包括基础聚合物的涂层材料和具有抑制基础聚合物的氧化劣化反应的官能团的抗氧化剂。该方法包括对涂料进行热降解试验; 基于抗氧化剂的官能团的吸光度与基础聚合物的吸光度的比率，确定热降解试验中两个或更多个时间点的涂料的降解水平和降解速率; 从而评估涂料的使用寿命。

5. 发明授权

US08569331B2 Substituted benzo[f]lmidazo[1,2-d]pyrido[2,3-b][1,4]diazepine compounds 有权
标题翻译：取代的苯并[f]咪唑并[1,2-d]吡啶并[2,3-b] [1,4]二氮杂化合物
公开(公告)号：US08569331B2
公开(公告)日：2013-10-29
申请号：US13286294
申请日：2011-11-01
申请人： Mark A. Ashwell , Sudharshan Eathiraj , Anton Filikov , Steffi Koerner , Jean-Marc Lapierre , Yanbin Liu , Rocio Palma , David Vensel , Shin Iimura , Akiko Shiina , Kenichi Yoshida , Takanori Yamazaki , Akihisa Matsuda
发明人： Mark A. Ashwell , Sudharshan Eathiraj , Anton Filikov , Steffi Koerner , Jean-Marc Lapierre , Yanbin Liu , Rocio Palma , David Vensel , Shin Iimura , Akiko Shiina , Kenichi Yoshida , Takanori Yamazaki , Akihisa Matsuda
IPC分类号： A61K31/44
CPC分类号： C07D471/14 , A61K31/551 , Y02A50/401 , Y02A50/409 , Y02A50/411
摘要： The present invention relates to substituted benzo[f]imidazo[1,2-d]pyrido[2,3-b][1,4]diazepine compounds and methods of synthesizing these compounds. The present invention also relates to pharmaceutical compositions containing substituted benzo[f]imidazo[1,2-d]pyrido[2,3-b][1,4]diazepine compounds and methods of treating cell proliferative disorders, such as cancer, by administering these compounds and pharmaceutical compositions to subjects in need thereof.
摘要翻译：本发明涉及取代的苯并[f]咪唑并[1,2-d]吡啶并[2,3-b] [1,4]二氮杂化合物和合成这些化合物的方法。本发明还涉及含有取代的苯并[f]咪唑并[1,2-d]吡啶并[2,3-b] [1,4]二氮杂化合物的药物组合物和治疗细胞增殖性疾病如癌症的方法，将这些化合物和药物组合物给予需要的受试者。

6. 发明申请

US20130136371A1 IMAGE FILTER DEVICE, DECODING APPARATUS, ENCODING APPARATUS, AND DATA STRUCTURE 有权
标题翻译：图像滤波装置，解码装置，编码装置和数据结构
公开(公告)号：US20130136371A1
公开(公告)日：2013-05-30
申请号：US13704169
申请日：2011-06-02
申请人： Tomohiro Ikai , Tomoyuki Yamamoto , Takanori Yamazaki
发明人： Tomohiro Ikai , Tomoyuki Yamamoto , Takanori Yamazaki
IPC分类号： G06T5/00 , G06T9/00
CPC分类号： G06T5/001 , G06T9/004 , H04N19/117 , H04N19/14 , H04N19/17 , H04N19/176 , H04N19/593 , H04N19/70 , H04N19/82
摘要： An adaptive filter includes: an edge direction detection section which discriminates directionality of an input image in each of a plurality of unit regions constituting the input image; a region classification section which classifies the each of the plurality of unit regions into one of a plurality of unit region groups in accordance with to which of a plurality of predetermined groups the directionality of the input image in the each of the plurality of unit regions belongs, the directionality having been discriminated by the edge direction detection section; and a filter process section which calculates a pixel value of the each pixel of an output image by use of a filter coefficient group optimized for a unit region group to which a unit region including the each pixel belongs.
摘要翻译：自适应滤波器包括：边缘方向检测部，其识别构成输入图像的多个单位区域中的每一个中的输入图像的方向性; 区域分类部，根据多个单位区域中的每一个所属的输入图像的方向性，将多个单位区域中的每一个分类为多个单位区域组中的一个，所述方向性被所述边缘方向检测部所区分; 以及滤波处理部，其通过使用针对包括每个像素的单位区域属于的单位区域群优化的滤波器系数组来计算输出图像的每个像素的像素值。

7. 发明授权

US07202416B2 Electromagnetic insulation wire, and method and apparatus for manufacturing the same 失效
标题翻译：电磁绝缘线及其制造方法和装置
公开(公告)号：US07202416B2
公开(公告)日：2007-04-10
申请号：US10886587
申请日：2004-07-09
申请人： Matahiro Komuro , Naofumi Chiwata , Masato Miyataki , Takanori Yamazaki
发明人： Matahiro Komuro , Naofumi Chiwata , Masato Miyataki , Takanori Yamazaki
IPC分类号： H01B7/00
CPC分类号： H01B3/30 , H01B11/146 , H01B13/14 , Y10T29/49123
摘要： The present invention is concerned with an electromagnetic insulation wire, a method of manufacturing the same and an apparatus for manufacturing the same. The wire comprises a conductor and an electromagnetic insulation coat containing magnetic powder dispersed in a resin matrix. The particles of the powder are oriented in the coat in the circumferential direction of the conductor. The particles are oriented in the magnetic field, while the conductor and the composite material are passed through a die heated to a certain temperature.
摘要翻译：本发明涉及一种电磁绝缘线及其制造方法及其制造方法。导线包括导体和包含分散在树脂基体中的磁粉的电磁绝缘涂层。粉末的颗粒在导体的圆周方向上在涂层中取向。颗粒在磁场中取向，同时导体和复合材料通过加热到一定温度的模头。

8. 发明申请

US20070058296A1 Magnetic head slider with flying height control 有权
标题翻译：磁头滑块具有飞行高度控制
公开(公告)号：US20070058296A1
公开(公告)日：2007-03-15
申请号：US11516828
申请日：2006-09-06
申请人： Kiyoshi Hashimoto , Hidekazu Kohira , Takanori Yamazaki , Koji Miyake
发明人： Kiyoshi Hashimoto , Hidekazu Kohira , Takanori Yamazaki , Koji Miyake
IPC分类号： G11B5/60 , G11B21/22
CPC分类号： G11B5/6005 , G11B5/6064
摘要： Embodiments of the invention provide a slider structure able to lower a flying height compensation ratio caused by a projecting deformation of an air bearing surface of a slider by a flying height control mechanism and afford a change in flying height with a low control power. In one embodiment, a slider is provided with a leading edge, an air bearing surface, and a trailing edge. The air bearing surface includes a front pad, the front pad being made up of a front step bearing surface, leading rail surfaces, and side step bearing surfaces. The air bearing surface also includes a negative pressure groove surface surrounded by the front pad. The air bearing surface further includes a rear pad, the rear pad being made up of a rear step bearing surface formed at the same depth as the depth of the front step bearing surface and positioned on the trailing edge side, a trailing rail surface, an intermediate groove deeper than the trailing rail surface, and a trailing pad surface lying at the same height as the trailing rail surface. The front and both sides of the trailing pad surface are surrounded by the trailing rail surface.
摘要翻译：本发明的实施例提供一种滑块结构，其能够通过飞行高度控制机构降低由滑块的空气轴承表面的突出变形引起的飞行高度补偿比，并且以较低的控制功率提供飞行高度的变化。在一个实施例中，滑块设置有前缘，空气支承表面和后缘。空气轴承表面包括前垫，前垫由前台阶承载面，前导轨面和侧台承载面构成。空气轴承表面还包括由前垫包围的负压槽表面。空气轴承表面还包括后垫，后垫由后台阶承载表面构成，该后承载表面形成在与前阶梯承载表面的深度相同的深度并且位于后缘侧，后轨道表面，比后导轨表面更深的中间槽，以及位于与后导轨表面相同高度的后垫表面。尾垫表面的前侧和两侧被后导轨表面包围。

9. 发明授权

US07186794B2 Polymer treating method and apparatus 有权
标题翻译：聚合物处理方法和装置
公开(公告)号：US07186794B2
公开(公告)日：2007-03-06
申请号：US10958730
申请日：2004-10-06
申请人： Toshiharu Goto , Takanori Yamazaki
发明人： Toshiharu Goto , Takanori Yamazaki
IPC分类号： C08F6/00
CPC分类号： C08J11/24 , Y02P20/582 , Y02W30/706
摘要： A polymer treating method has the steps of: reacting a polymer compound with a reaction agent in a reaction vessel to generate a polymer treatment product; discharging the polymer treatment product containing the reaction agent from the reaction vessel; depressurizing the polymer treatment product; introducing the polymer treatment product into a degassing extruder; separating the reaction agent from the polymer treatment product through a vent box that is connected to upstream of the degassing extruder and that has a volume of equal to or more than that of the reaction vessel; and extruding the polymer treatment product from the degassing extruder.
摘要翻译：聚合物处理方法具有以下步骤：在反应容器中使高分子化合物与反应剂反应生成聚合物处理产物; 从反应容器中排出含有反应剂的聚合物处理产物; 减压聚合物处理产品; 将聚合物处理产物引入脱气挤出机中; 通过连接到脱气挤出机的上游并具有等于或大于反应容器的体积的排气箱将反应剂与聚合物处理产物分离; 并从脱气挤出机挤出聚合物处理产物。

10. 发明申请

US20070031646A1 Molded product and manufacturing method thereof 审中-公开
标题翻译：成型品及其制造方法
公开(公告)号：US20070031646A1
公开(公告)日：2007-02-08
申请号：US11497338
申请日：2006-08-02
申请人： Takanori Yamazaki , Naofumi Chiwata , Takenori Taki
发明人： Takanori Yamazaki , Naofumi Chiwata , Takenori Taki
IPC分类号： B29C43/18 , B32B15/04
CPC分类号： B29C45/14811 , B29C43/18 , B29C43/203 , B29C45/14221 , B29K2105/256 , B29K2705/00 , B29K2715/006 , B32B37/04 , B32B2307/206 , B32B2311/00 , Y10T156/1043 , Y10T156/1044 , Y10T428/239 , Y10T428/24942 , Y10T428/31678
摘要： A molded product and a method of manufacturing the same are disclosed, in which the insulating layer of uniform thickness is formed in a narrow clearance between plural metal bodies. Surroundings of metal plates spaced at specified intervals are covered with insulating polymer to insulate them electrically. A spacer polymer which consists of insulating polymer whose melting point is T1 is arranged between the metal plates, and a molded part which consists of insulating polymer whose melting point is T2(
摘要翻译：公开了一种成型品及其制造方法，其中均匀厚度的绝缘层形成在多个金属体之间的窄间隙中。以规定间隔隔开的金属板的周围用绝缘聚合物覆盖，以使它们电绝缘。由熔点为T 1的绝缘聚合物构成的间隔聚合物被布置在金属板之间，并且由熔点为T 2（

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