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    • 6. 发明授权
    • Controlled release osmotic pump
    • 控制释放渗透泵
    • US5672167A
    • 1997-09-30
    • US227968
    • 1994-04-15
    • Amulya L. AthaydeRolf A. FasteC. Russell Horres, Jr.Thomas P. Low
    • Amulya L. AthaydeRolf A. FasteC. Russell Horres, Jr.Thomas P. Low
    • A61K9/22A61M5/142A61M5/145A61M5/148
    • A61M5/1483A61M2005/14513A61M5/14248Y10S977/956
    • A portable osmotic pump, having two pouches (4,3) in pressure-transmitting relationship, the first (4) containing a pumped fluid, such as infusate (5), and the second (3), a driving fluid (36). The driving fluid is created and pressurized by activation of an osmotic pump, and the rate of infusion is controlled by a semipermeable membrane (10). Activation can be by rupturing a seal (11) or by opening a closed tube (58) to permit permeant (2) to contact the semipermeable membrane. Pulses of the pumped fluid can be achieved by delivery pulses of the permeant to the second pouch. The pouches can be designed to resist collapse of the first pouch by external forces on the pumped liquid, such as gravity, movement of the first pouch and negative pressures applied to the pumped liquid. The infusate pouch is manufactured separately and can be stored apart from the rest of the system.
    • 一种具有压力传递关系的两个袋(4,3)的便携式渗透泵,所述第一(4)包含诸如输液(5)和第二(3)的泵送流体,驱动流体(36)。 通过激活渗透泵来产生和加压驱动流体,并且输注速率由半透膜(10)控制。 活化可以是破裂密封件(11)或打开封闭管(58)以允许渗透物(2)接触半透膜。 泵送流体的脉冲可以通过渗透物向第二袋的输送脉冲来实现。 小袋可以被设计成抵抗泵送液体上的外力,例如重力,第一袋的运动和施加到泵送的液体上的负压,使第一袋的崩溃。 输液袋分开制造,可以与系统的其余部分分开储存。