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1. 发明授权

US07076115B2 Analysis of chemical data from images 失效
标题翻译：图像化学数据分析
公开(公告)号：US07076115B2
公开(公告)日：2006-07-11
申请号：US10803115
申请日：2004-03-16
申请人： Thomas Crevier , William B. Archibald , Marc Hornbostel , Dieter Schaefer , Thomas Boussie
发明人： Thomas Crevier , William B. Archibald , Marc Hornbostel , Dieter Schaefer , Thomas Boussie
IPC分类号： G06K9/36
CPC分类号： G01N35/085 , B01J19/0046 , B01J19/26 , B01J2219/00274 , B01J2219/00283 , B01J2219/00308 , B01J2219/0031 , B01J2219/00313 , B01J2219/00315 , B01J2219/00317 , B01J2219/00335 , B01J2219/00337 , B01J2219/00344 , B01J2219/00351 , B01J2219/00364 , B01J2219/00378 , B01J2219/0043 , B01J2219/00443 , B01J2219/00452 , B01J2219/00495 , B01J2219/00497 , B01J2219/005 , B01J2219/00511 , B01J2219/00515 , B01J2219/0052 , B01J2219/00527 , B01J2219/00536 , B01J2219/00583 , B01J2219/00585 , B01J2219/00587 , B01J2219/0059 , B01J2219/00596 , B01J2219/00605 , B01J2219/0061 , B01J2219/00612 , B01J2219/00659 , B01J2219/00675 , B01J2219/00689 , B01J2219/00691 , B01J2219/00702 , B01J2219/00704 , B01J2219/00707 , B01J2219/00722 , B01J2219/00738 , B01J2219/00745 , B01J2219/00747 , B01J2219/0075 , B01J2219/00754 , B82Y30/00 , C07F15/0066 , C07F15/045 , C40B30/08 , C40B40/14 , C40B40/18 , C40B50/14 , G01J4/00 , G01N15/0205 , G01N21/253 , G01N21/64 , G01N29/036 , G01N29/2425 , G01N29/348 , G01N29/4427 , G01N33/44 , G01N2015/0288 , G01N2015/0294 , G01N2291/106 , Y10T436/112499 , Y10T436/113332 , Y10T436/115831
摘要： Computer programs and computer-implemented methods implement techniques for evaluating experimental data from a library of materials. The techniques receive a plurality of images of a library of materials that includes an array of members associated with locations in the library. User input identifying a plurality of regions of interest is received. A series of reduced data values is determined for one or more of the regions of interest as a statistical function of a plurality of pixel values for pixels in the corresponding regions. A figure of merit is calculated from one or more of the series of reduced data values for a library member at the corresponding library location. The regions of interest include a plurality of pixels in the images and correspond to locations in the library.
摘要翻译：计算机程序和计算机实现的方法实施用于从材料库评估实验数据的技术。这些技术接收包括与库中的位置相关联的成员阵列的材料库的多个图像。接收识别感兴趣区域的用户输入。为一个或多个感兴趣区域确定一系列缩减数据值作为对应区域中的像素的多个像素值的统计函数。从相应库位置的库成员的一系列缩减数据值中计算一个品质因数。感兴趣的区域包括图像中的多个像素并且对应于库中的位置。

2. 发明授权

US06738529B1 Analysis of chemical data from images 有权
标题翻译：图像化学数据分析
公开(公告)号：US06738529B1
公开(公告)日：2004-05-18
申请号：US09415772
申请日：1999-10-08
申请人： Thomas Crevier , William B. Archibald , Marc Hornbostel , Dieter Schaefer , Thomas Boussie
发明人： Thomas Crevier , William B. Archibald , Marc Hornbostel , Dieter Schaefer , Thomas Boussie
IPC分类号： G06K936
CPC分类号： G01N35/085 , B01J19/0046 , B01J19/26 , B01J2219/00274 , B01J2219/00283 , B01J2219/00308 , B01J2219/0031 , B01J2219/00313 , B01J2219/00315 , B01J2219/00317 , B01J2219/00335 , B01J2219/00337 , B01J2219/00344 , B01J2219/00351 , B01J2219/00364 , B01J2219/00378 , B01J2219/0043 , B01J2219/00443 , B01J2219/00452 , B01J2219/00495 , B01J2219/00497 , B01J2219/005 , B01J2219/00511 , B01J2219/00515 , B01J2219/0052 , B01J2219/00527 , B01J2219/00536 , B01J2219/00583 , B01J2219/00585 , B01J2219/00587 , B01J2219/0059 , B01J2219/00596 , B01J2219/00605 , B01J2219/0061 , B01J2219/00612 , B01J2219/00659 , B01J2219/00675 , B01J2219/00689 , B01J2219/00691 , B01J2219/00702 , B01J2219/00704 , B01J2219/00707 , B01J2219/00722 , B01J2219/00738 , B01J2219/00745 , B01J2219/00747 , B01J2219/0075 , B01J2219/00754 , B82Y30/00 , C07F15/0066 , C07F15/045 , C40B30/08 , C40B40/14 , C40B40/18 , C40B50/14 , G01J4/00 , G01N15/0205 , G01N21/253 , G01N21/64 , G01N29/036 , G01N29/2425 , G01N29/348 , G01N29/4427 , G01N33/44 , G01N2015/0288 , G01N2015/0294 , G01N2291/106 , Y10T436/112499 , Y10T436/113332 , Y10T436/115831
摘要： Computer programs and computer-implemented methods are disclosed for extracting and analyzing combinatorial chemical data from images. The invention receives a stream of data, identifies a plurality of regions of interest and determines a series of values for one or more regions of interest. The library includes a plurality of members. The data stream includes a series of images of the library. Each region of interest corresponds to a location in each of the images and to a location in the library. The series of values for each region includes a value for each of the images. Particular embodiments have the following features. The invention calculates a figure of merit for a library member from each series of values. The stream of data comprises a series of images generated at a frequency of greater than about 1, 6, 12 or 30 frames per second. The series of images is captured from a beginning of a combinatorial experiment to an end of a commercial experiment. The regions of interest are identified after the series of images has been captured. The images are infrared images. The figure of merit is an emittance change, a phase transition point or a thermoelectric figure of merit for a library member. Regions of interest are identified by a user and have a user-defined shape. The series of values for each region is determined based on a user-defined computation. A graphical representation of the figures of merit is displayed.
摘要翻译：公开了用于从图像中提取和分析组合化学数据的计算机程序和计算机实现的方法。本发明接收数据流，识别多个感兴趣区域并确定一个或多个感兴趣区域的一系列值。图书馆包括多个成员。数据流包括图书馆的一系列图像。每个感兴趣区域对应于每个图像中的位置和库中的位置。每个区域的一系列值包括每个图像的值。具体实施例具有以下特征。本发明根据每一系列值计算库成员的品质因数。数据流包括以大于每秒大约1,6,12或30帧的频率生成的一系列图像。从组合实验的开始到商业实验的结束捕获一系列图像。在捕获一系列图像之后识别感兴趣的区域。图像是红外图像。品质因数是库成员的发射变化，相变点或热电优值。感兴趣区域由用户识别并具有用户定义的形状。基于用户定义的计算来确定每个区域的一系列值。显示品质因数的图形表示。

3. 发明申请

US20060135722A1 Substituted pyridyl amine catalysts and processes for polymerizing crystalline polymers 审中-公开
公开(公告)号：US20060135722A1
公开(公告)日：2006-06-22
申请号：US11353324
申请日：2006-02-14
申请人： Thomas Boussie , Gary Diamond , Christopher Goh , Keith Hall , Anne LaPointe , Margarete Leclerc , Cheryl Lund , Vince Murphy
发明人： Thomas Boussie , Gary Diamond , Christopher Goh , Keith Hall , Anne LaPointe , Margarete Leclerc , Cheryl Lund , Vince Murphy
IPC分类号： C08F110/06
CPC分类号： C07D213/74 , B01J2219/00722 , C07B2200/11 , C07D213/38 , C07D213/61 , C07D213/68 , C07F7/00 , C07F7/003 , C07F9/58 , C08F4/65908 , C08F4/65912 , C08F10/00 , C08F110/06 , C08F210/02 , C08F210/16 , C40B40/14 , C08F4/659 , C08F4/65904 , C08F2500/15 , C08F2500/02 , C08F210/10 , C08F212/08 , C08F210/14 , C08F4/64144 , C08F4/64113 , C08F4/64044
摘要： New ligands, compositions, metal-ligand complexes and arrays with pyridyl-amine ligands are disclosed that catalyze the polymerization of monomers into polymers. Certain of these catalysts with hafnium metal centers have high performance characteristics, including higher comonomer incorporation into ethylene/olefin copolymers, where such olefins are for example, 1-octene, isobutylene or styrene. Certain of the catalysts are particularly effective at polymerizing propylene to high molecular weight isotactic polypropylene in a solution process at a variety of polymerization conditions.

4. 发明授权

US06841127B2 In-Situ Injection and materials screening device 有权
标题翻译：原位注射和材料筛选装置
公开(公告)号：US06841127B2
公开(公告)日：2005-01-11
申请号：US10187406
申请日：2002-06-28
申请人： Trevor G. Frank , Keith A. Hall , William H. Chandler, Jr. , Thomas Boussie , Thomas J. Crevier , Leonid Matsiev , Christopher Goh
发明人： Trevor G. Frank , Keith A. Hall , William H. Chandler, Jr. , Thomas Boussie , Thomas J. Crevier , Leonid Matsiev , Christopher Goh
IPC分类号： G01N31/16 , B01J19/00 , C08F4/00 , G01N21/78 , G01N25/72 , G01N31/10 , G01N35/00 , G01N35/02 , G01N33/48 , G01N15/06 , G01N21/00 , G01N31/00 , G01N33/00
CPC分类号： G01N31/10 , B01J19/0046 , G01N25/72 , G01N35/025 , G01N2035/00188 , Y10T436/10 , Y10T436/11 , Y10T436/110833 , Y10T436/113332 , Y10T436/114165 , Y10T436/25
摘要： An apparatus for in-situ injection of one or more chemical components into a reaction chamber is disclosed. The apparatus includes a reaction chamber for receiving one or more libraries, each of the libraries comprising two or more samples. The reaction chamber is configured to form a sealed enclosure. The apparatus further includes an injection manifold supporting injectors for in-situ injection of one or more chemical components onto respective samples of the one or more libraries in the pressurized sealed reaction chamber.
摘要翻译：公开了一种用于将一种或多种化学成分原位注入反应室的装置。该装置包括用于接收一个或多个库的反应室，每个库包括两个或更多个样品。反应室被配置成形成密封的外壳。该装置还包括支撑注射器的注射歧管，用于将一个或多个化学组分原位注射到加压密封反应室中的一个或多个文库的相应样品上。

5. 发明授权

US06756195B2 Polymerization method from the combinatorial synthesis and analysis of organometallic compounds and catalysts 有权
标题翻译：从组合合成和分析有机金属化合物和催化剂的聚合方法
公开(公告)号：US06756195B2
公开(公告)日：2004-06-29
申请号：US09235368
申请日：1999-01-21
申请人： W. Henry Weinberg , Eric McFarland , Isy Goldwasser , Thomas Boussie , Howard Turner , Johannes A. M. Van Beek , Vince Murphy , Timothy Powers
发明人： W. Henry Weinberg , Eric McFarland , Isy Goldwasser , Thomas Boussie , Howard Turner , Johannes A. M. Van Beek , Vince Murphy , Timothy Powers
IPC分类号： C12Q100
CPC分类号： G01N21/6402 , B01J19/0046 , B01J2219/00315 , B01J2219/00317 , B01J2219/00364 , B01J2219/00378 , B01J2219/0043 , B01J2219/00443 , B01J2219/00497 , B01J2219/005 , B01J2219/00511 , B01J2219/00515 , B01J2219/0052 , B01J2219/00527 , B01J2219/00536 , B01J2219/00583 , B01J2219/00585 , B01J2219/0059 , B01J2219/00596 , B01J2219/00605 , B01J2219/0061 , B01J2219/00612 , B01J2219/00621 , B01J2219/00637 , B01J2219/00644 , B01J2219/00659 , B01J2219/00675 , B01J2219/00689 , B01J2219/00702 , B01J2219/00722 , B01J2219/00738 , B01J2219/00745 , B01J2219/00747 , B01J2219/0075 , B01J2219/00754 , B82Y30/00 , C07F15/0066 , C07F15/045 , C08F10/00 , C40B30/08 , C40B40/14 , C40B40/18 , C40B50/14 , C40B60/14 , G01J4/00 , G01N29/036 , G01N29/2425 , G01N29/348 , G01N29/4427 , G01N2291/02818 , G01N2291/0423 , G01N2291/106 , C08F4/7006 , C08F4/7081
摘要： The present invention relates, inter alia, to methodologies for the synthesis, screening and characterization of organometallic compounds and catalysts (e.g., homogeneous catalysts). The methods of the present invention provide for the combinatorial synthesis, screening and characterization of libraries of supported and unsupported organometallic compounds and catalysts (e.g., homogeneous catalysts). The methods of the present invention can be applied to the preparation and screening of large numbers of organometallic compounds which can be used not only as catalysts (e.g., homogeneous catalysts), but also as additives and therapeutic agents.
摘要翻译：本发明尤其涉及有机金属化合物和催化剂（例如均相催化剂）的合成，筛选和表征的方法。本发明的方法提供了负载和未负载的有机金属化合物和催化剂（例如均相催化剂）的文库的组合合成，筛选和表征。本发明的方法可用于大量有机金属化合物的制备和筛选，所述有机金属化合物不仅可用作催化剂（例如均相催化剂），而且可用作添加剂和治疗剂。

6. 发明授权

US06248540B1 Combinatorial synthesis and analysis of organometallic compounds and homogeneous catalysts 有权
标题翻译：有机金属化合物和均相催化剂的组合合成与分析
公开(公告)号：US06248540B1
公开(公告)日：2001-06-19
申请号：US09390001
申请日：1999-09-03
申请人： W. Henry Weinberg , Eric McFarland , Isy Goldwasser , Thomas Boussie , Howard Turner , Johannes A. M. Van Beek , Vince Murphy , Timothy Powers
发明人： W. Henry Weinberg , Eric McFarland , Isy Goldwasser , Thomas Boussie , Howard Turner , Johannes A. M. Van Beek , Vince Murphy , Timothy Powers
IPC分类号： B01J3100
CPC分类号： G01N21/6402 , B01J19/0046 , B01J2219/00315 , B01J2219/00317 , B01J2219/00364 , B01J2219/00378 , B01J2219/0043 , B01J2219/00443 , B01J2219/00497 , B01J2219/005 , B01J2219/00511 , B01J2219/00515 , B01J2219/0052 , B01J2219/00527 , B01J2219/00536 , B01J2219/00583 , B01J2219/00585 , B01J2219/0059 , B01J2219/00596 , B01J2219/00605 , B01J2219/0061 , B01J2219/00612 , B01J2219/00621 , B01J2219/00637 , B01J2219/00644 , B01J2219/00659 , B01J2219/00675 , B01J2219/00689 , B01J2219/00702 , B01J2219/00722 , B01J2219/00738 , B01J2219/00745 , B01J2219/00747 , B01J2219/0075 , B01J2219/00754 , B82Y30/00 , C07F15/0066 , C07F15/045 , C08F10/00 , C40B30/08 , C40B40/14 , C40B40/18 , C40B50/14 , C40B60/14 , G01J4/00 , G01N29/036 , G01N29/2425 , G01N29/348 , G01N29/4427 , G01N2291/02818 , G01N2291/0423 , G01N2291/106 , C08F4/7006 , C08F4/7081
摘要： The present invention relates, inter alia, to methodologies for the synthesis, screening and characterization of organometailic compounds and catalysts (e.g., homogeneous catalysts). The methods of the present invention provide for the combinatorial synthesis, screening and characterization of libraries of supported and unsupported organometallic compounds and catalysts (e.g., homogeneous catalysts). The methods of the present invention can be applied to the preparation and screening of large niumbers of organometallic compounds which can be used not only as catalysts (e.g., homogeneous catalysts), but also as additives and therapeutic agents.
摘要翻译：本发明尤其涉及有机元素化合物和催化剂（例如均相催化剂）的合成，筛选和表征的方法。本发明的方法提供了负载和未负载的有机金属化合物和催化剂（例如均相催化剂）的文库的组合合成，筛选和表征。本发明的方法可用于制备和筛选不仅可用作催化剂（例如均相催化剂），而且可用作添加剂和治疗剂的大型有机金属化合物。

7. 发明授权

US06242623B1 Compositions and metal complexes having ancillary ligands 失效
标题翻译：具有辅助配体的组合物和金属络合物
公开(公告)号：US06242623B1
公开(公告)日：2001-06-05
申请号：US09119318
申请日：1998-07-20
申请人： Thomas Boussie , Vince Murphy , Johannes A. M. van Beek
发明人： Thomas Boussie , Vince Murphy , Johannes A. M. van Beek
IPC分类号： C07F900
CPC分类号： C07F15/045 , C07F13/00 , C07F13/005 , C07F15/0086 , C07F15/02 , C07F15/025 , C07F15/04 , C07F15/06 , C07F15/065 , C08F10/00 , C08F110/02 , Y10S526/943 , C08F4/7022 , C08F4/7054 , C08F4/7031 , C08F4/7021 , C08F4/7055 , C08F4/69284 , C08F4/7029
摘要： Novel compositions and metal compounds having an ancillary ligand structure polymerize monomers and functionalized monomers, either alone or in the presence of an activator. The ancillary ligand structure is a chelating ligand that may optionally be further bound to the metal via a dative or covalent bond.
摘要翻译：具有辅助配体结构的新型组合物和金属化合物单独或在活化剂存在下聚合单体和官能化单体。辅助配体结构是螯合配体，其可任选地通过对位或共价键进一步与金属结合。

8. 发明授权

US06177528B1 Substituted aminomethylphosphines, compositions and coordination complexes of same, their synthesis and processes using same 失效
标题翻译：取代的氨基甲基膦，组合物及其配位络合物，其合成和使用相同的方法
公开(公告)号：US06177528B1
公开(公告)日：2001-01-23
申请号：US09460071
申请日：1999-12-14
申请人： Anne Marie LaPointe , Anil Guram , Timothy S. Powers , Bernd Jandeleit , Thomas Boussie , Cheryl Lund
发明人： Anne Marie LaPointe , Anil Guram , Timothy S. Powers , Bernd Jandeleit , Thomas Boussie , Cheryl Lund
IPC分类号： C08F444
CPC分类号： B01J31/1805 , B01J31/143 , B01J31/181 , B01J31/1815 , B01J31/183 , B01J31/189 , B01J31/2295 , B01J31/24 , B01J31/2404 , B01J31/2419 , B01J31/2447 , B01J2219/00308 , B01J2219/00315 , B01J2219/00736 , B01J2219/00738 , B01J2219/00747 , B01J2231/12 , B01J2231/42 , B01J2231/4211 , B01J2531/02 , B01J2531/0205 , B01J2531/0216 , B01J2531/46 , B01J2531/62 , B01J2531/64 , B01J2531/824 , B01J2531/84 , B01J2531/842 , B01J2531/847 , B01J2540/22 , C07C209/10 , C07C253/30 , C07D295/023 , C07F7/00 , C07F9/5004 , C07F9/58 , C07F9/59 , C07F9/60 , C07F9/650952 , C07F15/006 , C07F15/025 , C07F15/045 , C07F15/065 , C07F17/02 , C08F4/61925 , C08F10/00 , C08F110/02 , C08F2410/03 , C40B40/00 , Y10S526/943 , C08F4/7013
摘要： Novel aminomethylphosphine ligands have particular substituents on the central carbon atom. Such ligands form coordination complexes that may be catalysts for the polymerization of monomers or other catalytic induced reactions.
摘要翻译：新的氨基甲基膦配体在中心碳原子上具有特定的取代基。这种配体形成配位络合物，其可以是用于单体聚合或其它催化诱导反应的催化剂。

9. 发明申请

US20070166989A1 Substrate processing including a masking layer 有权
标题翻译：衬底处理包括掩模层
公开(公告)号：US20070166989A1
公开(公告)日：2007-07-19
申请号：US11647882
申请日：2006-12-29
申请人： Zachary Fresco , Chi-I Lang , Sandra Malhotra , Tony Chiang , Thomas Boussie , Nitin Kumar , Jinhong Tong , Anh Duong
发明人： Zachary Fresco , Chi-I Lang , Sandra Malhotra , Tony Chiang , Thomas Boussie , Nitin Kumar , Jinhong Tong , Anh Duong
IPC分类号： H01L21/44 , H01L21/4763 , H01L21/31
CPC分类号： H01L21/288 , B82Y30/00 , H01L21/3105 , H01L21/31058 , H01L21/76834 , H01L21/76849 , H01L21/7685
摘要： Methods for substrate processing are described. The methods include forming a material layer on a substrate. The methods include selecting constituents of a molecular masking layer (MML) to remove an effect of variations in the material layer as a result of substrate processing. The methods include normalizing the surface characteristics of the material layer by selectively depositing the MML on the material layer.
摘要翻译：描述基板处理方法。所述方法包括在基底上形成材料层。所述方法包括选择分子屏蔽层（MML）的成分以消除作为衬底处理的结果的材料层中的变化的影响。所述方法包括通过在材料层上选择性地沉积MML来使材料层的表面特性归一化。

10. 发明申请

US20060264020A1 Formation of a masking layer on a dielectric region to facilitate formation of a capping layer on electrically conductive regions separated by the dielectric region 有权
标题翻译：在电介质区域上形成掩模层，以便在由电介质区域分隔的导电区域上形成覆盖层
公开(公告)号：US20060264020A1
公开(公告)日：2006-11-23
申请号：US11132841
申请日：2005-05-18
申请人： David Lazovsky , Sandra Malhotra , Thomas Boussie
发明人： David Lazovsky , Sandra Malhotra , Thomas Boussie
IPC分类号： H01L21/44
CPC分类号： H01L21/76829 , B82Y30/00 , H01L21/02183 , H01L21/3148 , H01L21/31633 , H01L21/31695 , H01L21/3185 , H01L21/76826 , H01L21/76849
摘要： A masking layer is formed on a dielectric region of an electronic device so that, during subsequent formation of a capping layer on electrically conductive regions of the electronic device that are separated by the dielectric region, the masking layer inhibits formation of capping layer material on or in the dielectric region. The capping layer can be formed selectively on the electrically conductive regions or non-selectively; in either case (particularly in the latter), capping layer material formed over the dielectric region can subsequently be removed, thus ensuring that capping layer material is formed only on the electrically conductive regions. Silane-based materials, such as silane-based SAMs, can be used to form the masking layer. The capping layer can be formed of an electrically conductive material (e.g., a cobalt alloy, a nickel alloy, tungsten, tantalum, tantalum nitride), a semiconductor material, or an electrically insulative material, and can be formed using any appropriate process, including conventional deposition processes such as electroless deposition, chemical vapor deposition, physical vapor deposition or atomic layer deposition.
摘要翻译：在电子器件的电介质区域上形成掩模层，使得在随后在由电介质区域分离的电子器件的导电区域上形成覆盖层时，掩模层阻止在其上形成覆盖层材料在电介质区域。可以选择性地在导电区域或非选择性地形成覆盖层; 在任一情况下（特别是在后者中），可以随后去除在电介质区域上形成的覆盖层材料，从而确保覆盖层材料仅在导电区域上形成。可以使用诸如硅烷基SAM之类的硅烷基材料来形成掩模层。覆盖层可以由导电材料（例如，钴合金，镍合金，钨，钽，氮化钽），半导体材料或电绝缘材料形成，并且可以使用任何适当的工艺形成，包括常规沉积工艺如无电沉积，化学气相沉积，物理气相沉积或原子层沉积。

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