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1. 发明申请

US20120082724A1 DRY MOULDABLE DRUG FORMULATION 失效
标题翻译：干燥的药物配方
公开(公告)号：US20120082724A1
公开(公告)日：2012-04-05
申请号：US13285470
申请日：2011-10-31
申请人： THOMAS BUCH-RASMUSSEN , Søren Aasmul , James M. Flink , Philip Hansen , Jens Ulrik Poulsen , Claus Juul-Mortensen
发明人： THOMAS BUCH-RASMUSSEN , Søren Aasmul , James M. Flink , Philip Hansen , Jens Ulrik Poulsen , Claus Juul-Mortensen
IPC分类号： A61K9/00 , A61P37/04
CPC分类号： A61K9/145 , A61K9/0024
摘要： Solid pharmaceutical compositions for parenteral injection comprising a binder and at least one therapeutic agent. The pharmaceutical composition has the strength to be injected directly with the need of using cannulas or the like.
摘要翻译：用于肠胃外注射的固体药物组合物，其包含粘合剂和至少一种治疗剂。药物组合物具有直接注射使用插管等的强度。

2. 发明授权

US06485453B1 Cassette for storing and insertion of solid medicine 有权
标题翻译：用于储存和插入固体药物的盒子
公开(公告)号：US06485453B1
公开(公告)日：2002-11-26
申请号：US09548957
申请日：2000-04-13
申请人： Thomas Buch-Rasmussen , Søren Aasmul , James M. Flink , Philip Hansen , Claus Juul-Mortensen , Jens Ulrik Poulsen
发明人： Thomas Buch-Rasmussen , Søren Aasmul , James M. Flink , Philip Hansen , Claus Juul-Mortensen , Jens Ulrik Poulsen
IPC分类号： A61M3100
CPC分类号： A61M37/0069 , A61M31/007 , A61M2205/123
摘要： A cassette for storing and insertion of a solid medicine peg appears as a unit having a first bore (2) which accommodates the medicine peg (3) and has a diameter corresponding to the diameter of this peg (3), a second bore (4) in coaxial extension of the first bore (2) and having a diameter larger than the diameter of the first bore (2), an inserter having a shaft (5) fitting into the first bore (2) and a guiding head (6) in coaxial extension of the shaft (5) fitting into the second bore. The inserter shaft (5) has one end adjacent to the peg (3) and the other connected to the guiding head (6) which projects from the cassette. The head (6) fits into the second bore with a fitting providing a diffusion tight sealing and the distal end of the unit is closed by a membrane diffusion tightly sealing this distal end.
摘要翻译：用于存放和插入固体药物栓钉的盒子出现为具有容纳药物钉（3）的第一孔（2）的单元，并且具有对应于该栓钉（3）的直径的直径，第二孔（4）），其具有大于所述第一孔（2）的直径的直径，所述插入器具有装配到所述第一孔（2）中的轴（5）和引导头（6）在轴（5）的同轴延伸中装配到第二孔中。插入器轴（5）具有与钉（3）相邻的一端，另一端连接到从盒突出的引导头（6）。头部（6）通过具有扩散密封的配件装配到第二孔中，并且单元的远端通过密封该远端的膜扩散来封闭。

3. 发明授权

US06562011B1 Medication delivery device 失效
标题翻译：药物输送装置
公开(公告)号：US06562011B1
公开(公告)日：2003-05-13
申请号：US09348536
申请日：1999-07-07
申请人： Thomas Buch-Rasmussen , Benny Munk , Jens Ulrik Poulsen , Henrik Ljungreen , Peter Møller Jensen , Jens Møller Jensen
发明人： Thomas Buch-Rasmussen , Benny Munk , Jens Ulrik Poulsen , Henrik Ljungreen , Peter Møller Jensen , Jens Møller Jensen
IPC分类号： A61M500
CPC分类号： A61M5/24 , A61M5/31525 , A61M5/31535 , A61M5/31566 , A61M5/31578 , A61M2005/2407 , A61M2005/2488 , A61M2005/2492
摘要： The present invention relates to a medication delivery device comprising a cartridge assembly, a dosing assembly and optionally a needle assembly. The cartridge assembly comprises a cartridge having a stopper adapted to receive a plunger means. Furthermore, the cartridge assembly has one end sealed with a pierceable sealing, said end comprising coupling means for engaging a needle assembly, and another end comprising coupling means for engaging the dosing assembly. At least one of the coupling means of the cartridge assembly is unitarily moulded with the cartridge. The dosing assembly comprises a plunger means and has coupling means for engaging the cartridge assembly. The cartridge assembly and the dosing assembly are coupled together for delivering selected doses of medication. The cartridge is preferably moulded from a plastic material, such as a transparent material, and may be housed in a cartridge housing for protection of the cartridge. The coupling means may be selected from threaded locks, snap locks, hinged locks, or bajonet locks. The medication delivery device is especially suitable for delivering insulin, growth hormone or other medicines.
摘要翻译：本发明涉及药物输送装置，其包括药筒组件，剂量组合件和任选的针组件。盒组件包括具有适于容纳柱塞装置的止动件的盒。此外，盒组件具有用可刺破密封件密封的一端，所述端部包括用于接合针组件的联接装置，以及包括用于接合给药组件的联接装置的另一端。盒组件的联接装置中的至少一个与盒一体地模制。配料组件包括柱塞装置并具有用于接合盒组件的联接装置。药筒组件和剂量组合件联接在一起以递送选定剂量的药物。盒优选地由诸如透明材料的塑料材料成型，并且可以容纳在盒壳体中以保护盒。联接装置可以选自螺纹锁，卡扣锁，铰链锁或双面胶锁。药物输送装置特别适用于输送胰岛素，生长激素或其他药物。

4. 发明授权

US06533183B2 Coding of cartridges for an injection device 有权
公开(公告)号：US06533183B2
公开(公告)日：2003-03-18
申请号：US09846799
申请日：2001-05-01
申请人： Søren Aasmul , Jens Ulrik Poulsen
发明人： Søren Aasmul , Jens Ulrik Poulsen
IPC分类号： G06K710
CPC分类号： G06K1/121
摘要： A cartridge (1) for an injection device carries a code represented by a number of bars (2, 3, 4, 5) mainly perpendicular to the axis of the cartridge. The bars (2, 3, 4, 5) are mainly transparent and are each along its whole length provided with an optical grating which diffracts and reflects light impinging the surface carrying the code so that a minor part of this light is reflected from the surface of the bar as a set of light beams of which beams at least one is detected for the indication of the presence of the bar when said bar passes a reading light field. The reflections from the bars may be interpreted as representing “1”s and “0”s in a binary code.

5. 发明授权

US6010485A Working cylinder 失效
标题翻译：工作缸
公开(公告)号：US6010485A
公开(公告)日：2000-01-04
申请号：US932354
申请日：1997-09-17
申请人： Thomas Buch-Rasmussen , Jens Ulrik Poulsen , Henrik Ljunggreen , Jens M.o slashed.ller Jensen
发明人： Thomas Buch-Rasmussen , Jens Ulrik Poulsen , Henrik Ljunggreen , Jens M.o slashed.ller Jensen
IPC分类号： A61M5/31 , A61M5/178 , A61M5/20 , A61M5/315 , A61M39/00 , A61M5/00
CPC分类号： A61M5/31525 , A61M5/204 , A61M5/31595 , A61M5/31555 , A61M5/31561 , A61M5/3158
摘要： The present invention relates to a drug delivery system, comprising a reservoir from which set doses are apportioned, a dose setting mechanism by which the relative position of two elements is changed by a distance proportional to a set dose, and a push button by activation of which an element is moved a distance corresponding to the distance proportional to the set dose, further comprises a working cylinder having an open end into which a plunger fits, and a closed end at which an inlet and an outlet port connect the space beneath the plunger with an inlet communicating with the reservoir and an outlet communicating with a drug delivery member, respectively. Valves means at the inlet and outlet control the passages from the reservoir to the working cylinder and from the working cylinder to the drug delivery member, respectively. The cylinder with the plunger, and the injection member are independently exchangeable, disposable parts.
摘要翻译：本发明涉及一种药物递送系统，其包括分配设定剂量的储存器，剂量设定机构，通过该剂量设定机构将两个元件的相对位置改变与设定剂量成比例的距离，以及按钮，通过激活元件被移动到与设定剂量成比例的距离处的距离，还包括具有开口端的柱塞配合的工作缸和入口和出口连接柱塞下方的空间的封闭端其中入口与储存器连通并且分别与药物递送构件连通。阀门在入口和出口处分别控制从储存器到工作缸以及从工作缸到药物传送构件的通道。具有柱塞的气缸和注射构件可独立地更换，一次性部件。

6. 发明授权

US06656114B1 Method and a system for assisting a user in a medical self treatment, said self treatment comprising a plurality of actions 有权
标题翻译：方法和用于辅助用户进行医疗自我治疗的系统，所述自我治疗包括多个动作
公开(公告)号：US06656114B1
公开(公告)日：2003-12-02
申请号：US09462128
申请日：2000-10-30
申请人： Jens Ulrik Poulsen , Lars Hofmann Christensen , Søren Aasmul
发明人： Jens Ulrik Poulsen , Lars Hofmann Christensen , Søren Aasmul
IPC分类号： A61B500
CPC分类号： G06Q50/24 , A61B5/0002 , A61B5/14532 , A61B2560/0406 , A61B2560/0443 , A61B2562/0219 , A61M5/003 , A61M5/24 , A61M2205/505 , A61M2205/52 , G06F19/00 , G06F19/325 , G06F19/3468 , G06F19/3475 , G06F19/3481 , G16H10/60 , G16H50/50 , Y10S128/92 , Y10S128/921
摘要： A method of self treating a disease, such as diabetes, includes collecting in one or more databases data representing values of parameters that related to the self treatment. The data is processed to provide a plurality of alternate choices between two or more actions that may be taken and a corresponding value for each action is calculated. A computerized system may be employed to perform the above method and the system may include a computer readable medium for executing the method.
摘要翻译：自我治疗疾病如糖尿病的方法包括在一个或多个数据库中收集表示与自身治疗相关的参数值的数据。处理数据以在可以采取的两个或多个动作之间提供多个替代选择，并计算每个动作的相应值。可以采用计算机化系统来执行上述方法，并且系统可以包括用于执行该方法的计算机可读介质。

7. 发明授权

US06582408B1 Medical device 失效
标题翻译：医疗装置
公开(公告)号：US06582408B1
公开(公告)日：2003-06-24
申请号：US09349748
申请日：1999-07-08
申请人： Thomas Buch-Rasmussen , Benny Munk , Jens Ulrik Poulsen , Henrik Ljungreen , Peter Møller Jensen , Jens Møller Jensen
发明人： Thomas Buch-Rasmussen , Benny Munk , Jens Ulrik Poulsen , Henrik Ljungreen , Peter Møller Jensen , Jens Møller Jensen
IPC分类号： A61M500
CPC分类号： A61M5/315 , A61M5/24 , A61M5/3129 , A61M5/31525 , A61M5/31535 , A61M5/31566 , A61M5/31578 , A61M2005/2407 , A61M2005/2488 , A61M2005/2492
摘要： The present invention relates to a medication delivery device comprising a cartridge assembly, a dosing assembly and optionally a needle assembly. The cartridge assembly comprises a cartridge having a stopper adapted to receive a plunger. Furthermore, the cartridge assembly has one end sealed with a pierce able sealing, said end comprising coupling device for engaging a needle assembly, and another end comprising coupling device for engaging the dosing assembly. The dosing assembly comprises a plunger and has coupling device for engaging the cartridge assembly. The cartridge assembly and the dosing assembly are coupled together for delivering selected doses of medication. The device further comprises mechanism for securing that the plunger abuts on the stopper during use of the device, in particular when the dosing assembly is releasable coupled to the cartridge assembly. The securing mechanism is preferably a mechanism for preventing the cartridge assembly from being inadvertently released from the dosing assembly. The cartridge is preferably molded from a plastic material, such as a transparent material, and may be housed in a cartridge housing for protection of the cartridge. The medication delivery device is especially suitable for delivering insulin, growth hormone or the like medicines.
摘要翻译：本发明涉及药物输送装置，其包括药筒组件，剂量组合件和任选的针组件。盒组件包括具有适于容纳柱塞的止动件的盒。此外，盒组件具有用可刺穿密封件密封的一端，所述端部包括用于接合针组件的联接装置，以及包括用于接合给药组件的联接装置的另一端。配料组件包括柱塞并具有用于接合盒组件的联接装置。药筒组件和剂量组合件联接在一起以递送选定剂量的药物。该装置还包括用于在使用装置期间固定柱塞抵靠止动件的机构，特别是当定量给料组件可释放地联接到药筒组件时。固定机构优选地是用于防止盒组件被无意地从定量给料组件释放的机构。盒优选地由诸如透明材料的塑料材料模制，并且可以容纳在盒壳体中以保护盒。药物输送装置特别适用于输送胰岛素，生长激素等药物。

8. 发明授权

US06312413B1 Cylinder ampoule 失效
标题翻译：气瓶安瓿
公开(公告)号：US06312413B1
公开(公告)日：2001-11-06
申请号：US09176581
申请日：1998-10-21
申请人： Jens Møller Jensen , Thomas Buch-Rasmussen , Jens Ulrik Poulsen
发明人： Jens Møller Jensen , Thomas Buch-Rasmussen , Jens Ulrik Poulsen
IPC分类号： A61M500
CPC分类号： A61M5/31511 , A61M5/284 , A61M5/288 , A61M5/3129 , A61M5/31551 , A61M5/31561 , A61M5/31563 , A61M2005/3103
摘要： A cylinder ampoule (1) having a first end sealed by a closure through which an injection unit can communicate with a medicament in the ampoule and a second end closed by a piston (3) which can be forced into the ampoule (1) to press out a dose of a medicament stored in the ampoule between the closure and the piston (3) through said injection unit, which cylinder ampoule (1) has a non-circular inner cross section and which piston (3) has a non-circular cross section corresponding to the inner cross section of the ampoule (1). A piston rod (4) has a pressure foot (5) which has a cross section corresponding to the inner cross section of the ampoule (1) and is non-rotatably connected to the piston rod (4).
摘要翻译：一种气瓶安瓿（1），其具有由封闭件密封的第一端，注射单元可以通过该封闭件与安瓿中的药物连通，以及由活塞（3）封闭的第二端，所述活塞可以被迫进入安瓿（1）以按压通过所述注射单元排出存储在封闭件和活塞（3）之间的安瓿中的药物的剂量，该气瓶安瓿（1）具有非圆形的内部横截面，并且该活塞（3）具有非圆形横截面对应于安瓿（1）的内部横截面的截面。活塞杆（4）具有压力脚（5），其具有与安瓿（1）的内横截面对应的横截面，并且不可旋转地连接到活塞杆（4）。

9. 发明授权

US06540672B1 Medical system and a method of controlling the system for use by a patient for medical self treatment 有权
标题翻译：医疗系统和一种控制系统供病人用于医疗自我治疗的方法
公开(公告)号：US06540672B1
公开(公告)日：2003-04-01
申请号：US09450193
申请日：1999-11-29
申请人： Jan Henning Simonsen , Jens Ulrik Poulsen , Kent Halfdan Rokkjaer , Lars Hofmann Christensen , Søren Aasmul , Steffen Iav
发明人： Jan Henning Simonsen , Jens Ulrik Poulsen , Kent Halfdan Rokkjaer , Lars Hofmann Christensen , Søren Aasmul , Steffen Iav
IPC分类号： A61B500
CPC分类号： G06F19/3468 , A61B5/0022 , A61B5/14532 , A61B5/150022 , A61B5/150267 , A61B5/150305 , A61B5/150358 , A61B5/150412 , A61B5/15113 , A61B5/157 , A61B5/7264 , A61B2560/0406 , A61B2560/0443 , A61B2562/0219 , A61J1/03 , A61J7/0409 , A61J7/0454 , A61M5/178 , A61M5/31545 , A61M15/0065 , A61M15/0066 , A61M15/008 , A61M2005/3126 , A61M2205/05 , A61M2205/18 , A61M2205/3553 , A61M2205/3561 , A61M2205/3569 , A61M2205/3584 , A61M2205/3592 , A61M2205/50 , A61M2205/502 , A61M2205/52 , A61M2230/201 , G06F19/00 , G06F19/3418 , G06F19/3475 , G06F19/3481 , G16H10/60 , G16H50/20 , Y10S128/903
摘要： This invention relates to an system for self treatment. The system consists of several portable modules where one of the modules is designated as a master module. The master module controls, supervises and monitors all the mutual information and data exchange between itself and the rest of the modules. The modules can e.g. consist of a BGM, a doser, an inhaler, a tablet dispenser and a storage container. The modules may be able to generate and store data which is transmitted to the master module if it is within range and active. If the master module is not within range, the data is kept locally in the module until the master module is available or a new master module is designated. The master module or another specific module can send the data to an external unit like a computer or database for further processing. A physician or an expert care-team can access the data in the database and give guidance to the patient on the basis of these processed data. This processing could also be done automatically by utilization of an expert system.
摘要翻译：本发明涉及一种用于自我治疗的系统。该系统由几个便携式模块组成，其中一个模块被指定为主模块。主模块控制，监督和监视其本身与其余模块之间的所有互信息和数据交换。模块可以例如由BGM，加药器，吸入器，片剂分配器和储存容器组成。如果模块在范围和活动范围内，则模块可能能够生成和存储传输到主模块的数据。如果主模块不在范围内，则将数据本地保存在模块中，直到主模块可用或指定了新的主模块。主模块或另一个特定模块可以将数据发送到外部单元，如计算机或数据库进行进一步处理。医生或专家护理团队可以访问数据库中的数据，并根据这些处理的数据对患者进行指导。这种处理也可以通过利用专家系统自动完成。

10. 发明授权

US5954689A Jet injector 失效
标题翻译：射流喷射器
公开(公告)号：US5954689A
公开(公告)日：1999-09-21
申请号：US987716
申请日：1997-12-09
申请人： Jens Ulrik Poulsen
发明人： Jens Ulrik Poulsen
IPC分类号： A61M5/20 , A61M5/24 , A61M5/30 , A61M5/315
CPC分类号： A61M5/30 , A61M5/31551 , A61M5/31591 , A61M5/2046 , A61M5/24 , A61M5/31525
摘要： An injector comprising a changeable cylinder ampoule (2) containing medicine for a number of injections into which ampoule a piston (4) is pressed by a piston rod (9) driven by a drive mechanism to dispense a dose of medicine through a nozzle (5) as a high speed jet which penetrates the skin. The injector comprises a distal part (1) accommodating the cylinder ampoule (2) and a proximal part (8) containing the drive mechanism and the piston rod (9) which can be advanced a set distance by the drive mechanism when released, the distal and the proximal parts being provided with mutually engaging threads so that one of these parts can successively be screwed into the other to set a dose to be delivered by the device.
摘要翻译：一种注射器，包括可更换的气瓶安瓿（2），其包含用于多次注射的药物，安瓿活塞（4）被驱动机构驱动的活塞杆（9）按压，以通过喷嘴（5）分配一定剂量的药物）作为穿透皮肤的高速射流。所述喷射器包括容纳所述气瓶安瓿（2）的远端部分（1）和容纳所述驱动机构和所述活塞杆（9）的近端部分（8），当所述驱动机构和所述活塞杆（9）被释放时可以被所述驱动机构推进一定距离，并且近端部分设置有相互接合的螺纹，使得这些部件中的一个可以连续地拧入另一个部分以设定要由装置输送的剂量。

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