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1. 发明授权

US06794196B2 Deposited thin films and their use in detection, attachment and bio-medical applications 失效
标题翻译：沉积的薄膜及其在检测，附着和生物医学应用中的应用
公开(公告)号：US06794196B2
公开(公告)日：2004-09-21
申请号：US09739940
申请日：2000-12-19
申请人： Stephen J. Fonash , Sanghoon Bae , Daniel J. Hayes , Joseph Cuiffi
发明人： Stephen J. Fonash , Sanghoon Bae , Daniel J. Hayes , Joseph Cuiffi
IPC分类号： G01N100
CPC分类号： C23C16/511 , B81B2201/0214 , B81C1/0038 , B81C2201/0176 , C23C16/24 , G01N21/17 , G01N27/44717 , Y10T436/119163 , Y10T436/25 , Y10T436/2575
摘要： The present invention is directed to the use of deposited thin films for chemical or biological analysis. The invention further relates to the use of these thin films in separation adherence and detection of chemical of biological samples. Applications of these thin films include desorption-ionization mass spectroscopy, electrical contacts for organic thin films and molecules, optical coupling of light energy for analysis, biological materials manipulation, chromatographic separation, head space adsorbance media, media for atomic molecular adsorbance or attachment, and substrates for cell attachment.
摘要翻译：本发明涉及使用沉积的薄膜进行化学或生物分析。本发明还涉及这些薄膜在分离粘附和生物样品化学检测中的应用。这些薄膜的应用包括解吸电离质谱，有机薄膜和分子的电接触，用于分析的光能的光耦合，生物材料操作，色谱分离，顶空吸附介质，用于原子分子吸附或附着的介质，以及细胞附着物。

2. 发明授权

US07052616B2 Fabrication of molecular scale devices using fluidic assembly 有权
标题翻译：使用流体组件制造分子尺度装置
公开(公告)号：US07052616B2
公开(公告)日：2006-05-30
申请号：US10219955
申请日：2002-08-14
申请人： Stephen J. Fonash , Daniel J. Hayes , Wook Jun Nam , Joseph Cuiffi
发明人： Stephen J. Fonash , Daniel J. Hayes , Wook Jun Nam , Joseph Cuiffi
IPC分类号： C23F1/00
CPC分类号： B01J19/0093 , B01J2219/00783 , B01J2219/00819 , B01J2219/00835 , B01J2219/00837 , B01J2219/00853 , B01L3/5027 , B82Y15/00 , F15C5/00 , F16K99/0001 , F16K99/0003 , F16K99/0046 , F16K99/0051 , F16K2099/0073 , F16K2099/0074 , F16K2099/008 , F16K2099/0084
摘要： There is disclosed a method providing micro-scale devices, nano-scale devices, or devices having both nano-scale and micro-scale features. The method of the invention comprises fluidic assembly and various novel devices produced thereby. A variety of nanofluidic and molecular electronic type devices and structures having applications such as filtering and genetic sequencing are provided by the invention.
摘要翻译：公开了一种提供具有纳米尺度和微尺度特征的微尺度装置，纳米级装置或装置的方法。本发明的方法包括流体组装和由此制造的各种新型装置。本发明提供了具有诸如过滤和遗传测序等应用的多种纳米流体和分子电子型装置和结构。

3. 发明授权

US07427526B2 Deposited thin films and their use in separation and sacrificial layer applications 失效
标题翻译：沉积的薄膜及其在分离和牺牲层应用中的应用
公开(公告)号：US07427526B2
公开(公告)日：2008-09-23
申请号：US09836449
申请日：2001-04-17
申请人： Stephen J. Fonash , Wook Jun Nam , Youngchul Lee , Kyuhwan Chang , Daniel J. Hayes , A. Kaan Kalkan , Sanghoon Bae
发明人： Stephen J. Fonash , Wook Jun Nam , Youngchul Lee , Kyuhwan Chang , Daniel J. Hayes , A. Kaan Kalkan , Sanghoon Bae
IPC分类号： H01L21/00
CPC分类号： B81C1/0038 , B81C1/00119 , B81C1/00476 , B81C2201/0115 , G01N21/17 , G01N27/44717 , Y10T29/49108
摘要： This invention uses large surface to volume ratio materials for separation, release layer, and sacrificial material applications. The invention outlines the material concept, application designs, and fabrication methodologies. The invention is demonstrated using deposited column/void network materials as examples of large surface to volume ratio materials. In a number of the specific applications discussed, it is shown that it is advantageous to create structures on a laminate on a mother substrate and then, using the separation layer material approach, to separate this laminate from the mother substrate using the present separation scheme. It is also shown that the present materials have excellent release layer utility. In a number of applications it is also shown how the approach can be used to uniquely form cavities, channels, air-gaps, and related structures in or on various substrates. Further, it is demonstrated that it also can be possible and advantageous to combine the schemes for cavity formation with the scheme for laminate separation.
摘要翻译：本发明使用大的表面体积比的材料用于分离，剥离层和牺牲材料应用。本发明概述了材料概念，应用设计和制造方法。本发明使用沉积柱/空隙网络材料作为大表面积与体积比的材料的实例进行了说明。在讨论的许多具体应用中，显示了在母基板上的层压体上产生结构，然后使用分离层材料方法，使用本分离方案将该层压体与母基板分离是有利的。还显示出本发明材料具有优异的脱模层效用。在许多应用中，还显示了该方法如何用于在各种基底中或其上独特地形成腔，通道，气隙和相关结构。此外，证明了将空腔形成方案与层压分离方案组合也是有可能和有利的。

4. 发明授权

US07122790B2 Matrix-free desorption ionization mass spectrometry using tailored morphology layer devices 有权
公开(公告)号：US07122790B2
公开(公告)日：2006-10-17
申请号：US10144456
申请日：2002-05-13
申请人： Stephen J. Fonash , Ali Kaan Kalkan , Joseph Cuiffi , Daniel J. Hayes
发明人： Stephen J. Fonash , Ali Kaan Kalkan , Joseph Cuiffi , Daniel J. Hayes
IPC分类号： B01D59/44
CPC分类号： G01N1/405 , C23C16/24 , C23C16/511 , G01N21/17 , G01N27/44717 , G01N2001/045 , H01J49/162 , H01L51/0038 , H01L51/4253 , Y10T428/24802 , Y10T428/31678 , Y10T436/25
摘要： There is disclosed an apparatus for providing an ionized analyte for mass analysis by photon desorption comprising at least one layer for contacting an analyte, and a substrate on which said layer is deposited. Upon irradiation of said apparatus, said analyte desorbs and ionizes for analysis by mass spectrometry. The layer or layers of said apparatus comprise a continuous film, a discontinuous film or any combinations thereof.

5. 发明授权

US07309620B2 Use of sacrificial layers in the manufacture of high performance systems on tailored substrates 失效
标题翻译：在定制底材上制造高性能系统时使用牺牲层
公开(公告)号：US07309620B2
公开(公告)日：2007-12-18
申请号：US10340723
申请日：2003-01-13
申请人： Stephen J. Fonash , Handong Li , Youngchul Lee , Joseph D. Cuiffi , Daniel J. Hayes
发明人： Stephen J. Fonash , Handong Li , Youngchul Lee , Joseph D. Cuiffi , Daniel J. Hayes
IPC分类号： H01L21/00
CPC分类号： H01L27/1266 , B81C99/008 , G02B6/132 , G02B6/136 , G02B2006/12169 , G02B2006/12176 , H01L21/2007 , H01L21/568 , H01L21/6835 , H01L21/76251 , H01L24/97 , H01L27/1214 , H01L2221/68318 , H01L2924/01004 , H01L2924/01005 , H01L2924/01006 , H01L2924/01013 , H01L2924/01032 , H01L2924/01033 , H01L2924/01039 , H01L2924/01057 , H01L2924/09701 , H01L2924/12042 , H01L2924/19042 , H01L2924/3025 , H01M8/1097 , Y02P70/56 , Y10S438/96 , Y10S438/977 , H01L2924/00
摘要： The invention relates to methods for preparing a removable system on a mother substrate. The method deposits a high surface to volume sacrificial layer on a mother substrate and stabilizes the sacrificial layer by a) removing volatile chemical species in and on the sacrificial layer and/or b) modifying the surface of the layer. The method coats over the sacrificial layer with a capping medium. A system is the fabricated on the capping medium. The method provides through holes to access the sacrificial layer. The method may also apply a top layer onto the system to form a covered system. The invention also includes the step of removing the sacrificial layer to release the system from the mother substrate. Methods of the invention also include selectively removing a portion of the system and capping layers to form void regions defining an array of islands composed of device, structure, or system and capping layer regions, and optionally filling the island-defining void region with a sacrificial material. In such methods the sacrificial material and the high surface to volume sacrificial layer are removed to release the system from the mother substrate. Methods of the invention also include applying a layer to the capping material side of the released system to form a configuration wherein the system is substantially within a bending-stress reduced neutral plane. The systems fabricated according to the invention may be placed on a wide variety of suitable substrates, including flexible substrates.
摘要翻译：本发明涉及在母基板上制备可移除系统的方法。该方法在母体衬底上沉积高表面到体积的牺牲层，并通过以下步骤使牺牲层稳定：a）去除牺牲层中和/或牺牲层上的挥发性化学物质和/或b）改变该层的表面。该方法用覆盖介质涂覆在牺牲层上。系统是在封盖介质上制造的。该方法提供通孔以进入牺牲层。该方法还可以将顶层应用到系统上以形成被覆盖的系统。本发明还包括去除牺牲层以从母体衬底释放系统的步骤。本发明的方法还包括选择性地去除系统的一部分和封盖层，以形成限定由器件，结构或系统和覆盖层区域组成的岛阵列的空隙区域，并且可选地用牺牲层填充岛状限定空隙区域材料。在这种方法中，去除了牺牲材料和高表面到体积的牺牲层，以从母体衬底释放系统。本发明的方法还包括向释放系统的封盖材料侧施加一层以形成其中系统基本上在弯曲应力减小的中性平面内的构造。根据本发明制造的系统可以放置在各种合适的基板上，包括柔性基板。

6. 发明授权

US08183167B1 Wash-durable, antimicrobial and antifungal textile substrates 有权
标题翻译：耐洗涤，抗菌和抗真菌纺织品基材
公开(公告)号：US08183167B1
公开(公告)日：2012-05-22
申请号：US12016555
申请日：2008-01-18
申请人： James L. Delattre , Daniel J. Hayes , Joseph Cuiffi , Matthew Henry , James Kundrat , Paul Carrigan
发明人： James L. Delattre , Daniel J. Hayes , Joseph Cuiffi , Matthew Henry , James Kundrat , Paul Carrigan
IPC分类号： D03D15/00 , D04H1/00 , D02G3/00
CPC分类号： D03D15/0066 , D01F1/103 , Y10T428/2927 , Y10T442/3065 , Y10T442/3089 , Y10T442/3976 , Y10T442/696 , Y10T442/697 , Y10T442/699
摘要： Substrates that exhibit antimicrobial and/or antifungal characteristics that persist through the useful life of the substrate, and more particularly textile substrates infused with or covalently bound to well-dispersed antimicrobial nanoparticles, such as silver and/or copper nanoparticles, which exhibit persistent and demonstrable bacteriocidal, bacteriostatic, fungicidal, fungistatic behavior through numerous wash cycles. Methods of manufacturing such substrates are also provided.
摘要翻译：表现出抗基底和/或抗真菌特性的底物，其持续基底的使用寿命，更特别是注入或共价结合到良好分散的抗微生物纳米颗粒（例如银和/或铜纳米颗粒）的织物基质，其表现出持久和可证实的杀菌，抑菌，杀真菌，抗菌行为。还提供了制造这种基板的方法。

7. 发明申请

US20130303402A1 Detection and Molecular Weight Determination of Organic Vapors 有权
标题翻译：有机蒸汽的检测和分子量测定
公开(公告)号：US20130303402A1
公开(公告)日：2013-11-14
申请号：US13980068
申请日：2012-01-19
申请人： Isiah M. Warner , Bishnu P. Regmi , Bilal El-Zahab , Daniel J. Hayes
发明人： Isiah M. Warner , Bishnu P. Regmi , Bilal El-Zahab , Daniel J. Hayes
IPC分类号： B01J20/22
CPC分类号： B01J20/22 , G01N29/022 , G01N29/036 , G01N33/0047 , G01N2291/021 , G01N2291/0426
摘要： Composite films comprising an organic salt (or GUMBOS) such as 1-n-butyl-2,3-dimethylimidazolium hexafluoro-phosphate and a polymer such as cellulose acetate are prepared. These films are useful in detecting vapors of volatile organic compounds, and in determining their molecular weights. A quartz crystal microbalance-based sensor was designed by depositing a thin film of this composite material on the gold electrode surface of a quartz crystal resonator. The sensor exhibited rapid response toward a variety of volatile organic compounds, and complete regeneration, high sensitivity, low detection limits, and wide dynamic ranges. The ratio of the change in frequency to the change in motional resistance is a concentration-independent quantity that is proportional to the molecular weight of the absorbed chemical species. These properties facilitate the easy identification and molecular weight determination of a broad range of organic vapors.
摘要翻译：制备包含有机盐（或GUMBOS）如1-正丁基-2,3-二甲基咪唑鎓六氟磷酸盐和聚合物如乙酸纤维素的复合膜。这些膜可用于检测挥发性有机化合物的蒸气，以及确定其分子量。通过在石英晶体谐振器的金电极表面上沉积该复合材料的薄膜来设计石英晶体微量天平传感器。传感器对各种挥发性有机化合物表现出快速反应，完全再生，灵敏度高，检测限低，动态范围广。频率变化与运动阻力变化的比率是与吸收的化学物质的分子量成比例的浓度非依赖性量。这些性质有助于容易地鉴定和分子量测定范围广泛的有机蒸气。

8. 发明授权

US09782744B2 Detection and molecular weight determination of organic vapors 有权
公开(公告)号：US09782744B2
公开(公告)日：2017-10-10
申请号：US13980068
申请日：2012-01-19
申请人： Isiah M. Warner , Bishnu P. Regmi , Bilal El-Zahab , Daniel J. Hayes
发明人： Isiah M. Warner , Bishnu P. Regmi , Bilal El-Zahab , Daniel J. Hayes
IPC分类号： B01J20/22 , G01N33/00 , G01N29/02 , G01N29/036
CPC分类号： B01J20/22 , G01N29/022 , G01N29/036 , G01N33/0047 , G01N2291/021 , G01N2291/0426
摘要： Composite films comprising an organic salt (or GUMBOS) such as 1-n-butyl-2,3-dimethylimidazolium hexafluorophosphate and a polymer such as cellulose acetate are prepared. These films are useful in detecting vapors of volatile organic compounds, and in determining their molecular weights. A quartz crystal microbalance-based sensor was designed by depositing a thin film of this composite material on the gold electrode surface of a quartz crystal resonator. The sensor exhibited rapid response toward a variety of volatile organic compounds, and complete regeneration, high sensitivity, low detection limits, and wide dynamic ranges. The ratio of the change in frequency to the change in motional resistance is a concentration-independent quantity that is proportional to the molecular weight of the absorbed chemical species. These properties facilitate the easy identification and molecular weight determination of a broad range of organic vapors.

9. 发明申请

US20110284094A1 Liquid leak control appliance pedestal 审中-公开
标题翻译：液体泄漏控制装置基座
公开(公告)号：US20110284094A1
公开(公告)日：2011-11-24
申请号：US12800595
申请日：2010-05-18
申请人： Edward A. Chilcoat , Daniel J. Hayes
发明人： Edward A. Chilcoat , Daniel J. Hayes
IPC分类号： E03B9/00 , B23P11/00 , E03B5/00
CPC分类号： A47L15/4212 , A47L15/4223 , D06F39/081 , D06F39/085 , D06F39/125 , F17D1/14 , F17D5/02 , Y10T29/49826 , Y10T137/0402 , Y10T137/5835 , Y10T137/8158 , Y10T137/86043 , Y10T137/86067
摘要： Appliance pedestal that contains liquid leaks due to condensation, overflow, or system failure originating from the supported liquid filled or handling appliance, provides for multiple methods of discharge of collected liquids, and reduces installation and maintenance requirements and their associated hazards and provides an improved ergonomic operating position for the appliance operator.
摘要翻译：由于由支撑液体填充或处理设备引起的冷凝，溢流或系统故障而含有液体泄漏的电器底座提供了多种排出收集液体的方法，并降低了安装和维护要求及其相关危害，并提供了改进的人体工程学操作员的操作位置。

10. 发明授权

US09603503B2 Liquid leak control appliance pedestal 有权
公开(公告)号：US09603503B2
公开(公告)日：2017-03-28
申请号：US12800595
申请日：2010-05-18
申请人： Edward A. Chilcoat , Daniel J. Hayes
发明人： Edward A. Chilcoat , Daniel J. Hayes
IPC分类号： A47L15/42 , D06F39/08 , D06F39/12 , F17D1/14 , F17D5/02
CPC分类号： A47L15/4212 , A47L15/4223 , D06F39/081 , D06F39/085 , D06F39/125 , F17D1/14 , F17D5/02 , Y10T29/49826 , Y10T137/0402 , Y10T137/5835 , Y10T137/8158 , Y10T137/86043 , Y10T137/86067
摘要： Appliance pedestal that contains liquid leaks due to condensation, overflow, or system failure originating from the supported liquid filled or handling appliance, provides for multiple methods of discharge of collected liquids, and reduces installation and maintenance requirements and their associated hazards and provides an improved ergonomic operating position for the appliance operator.

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