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1. 发明授权

US4244642A Aperture card reader with automatic and manual card feed 失效
标题翻译：光圈读卡器，带有自动和手动进纸
公开(公告)号：US4244642A
公开(公告)日：1981-01-13
申请号：US49967
申请日：1979-06-19
申请人： Shiro Toriumi , Hiroshi Endo , Takao Saijo , Takanori Saito , Kuniaki Kamimura
发明人： Shiro Toriumi , Hiroshi Endo , Takao Saijo , Takanori Saito , Kuniaki Kamimura
IPC分类号： G03B27/58 , G03B21/11 , G03B21/64 , G06K17/00 , G03B23/14 , B65H5/26
CPC分类号： G03B21/116 , G06K17/0016
摘要： An aperture card reader is equipped with a unit detachably mountable on the main body for automatically feeding aperture cards. The aperture card can automatically be placed between presser plates while the unit is mounted on the main body or, alternatively, can be manually fed when the unit is detached from the main body. The aperture card is automatically fed between the presser plates with the card in a position in which the minor sides of the aperture card are oriented in the direction of feed, while the card can be manually placed between the presser plates by feeding the card in a position in which the major sides of the card are oriented in the direction of feed. The image of the microfilm mounted on the aperture card can be projected on a screen in a horizontal position when the card is fed automatically, or in a vertical position when the card is fed manually.
摘要翻译：光圈读卡器配备有可拆卸地安装在主体上用于自动馈送光圈卡的单元。当单元安装在主体上时，光圈卡可以自动放置在压板之间，或者当本机与主体分离时可以手动进给。光圈卡被自动地进给到压板与卡之间的位置中，孔卡的小侧在进给方向上定向，而卡可以通过将卡馈送到卡片中来手动地放置在压板之间卡的主要侧面朝向进给方向的位置。安装在孔卡上的缩微胶片的图像可以在卡被自动进给时处于水平位置的屏幕上，或者当手动进给卡时处于垂直位置。

2. 发明授权

US4278346A Reading and printing apparatus 失效
标题翻译：阅读和打印设备
公开(公告)号：US4278346A
公开(公告)日：1981-07-14
申请号：US52916
申请日：1979-06-26
申请人： Shiro Toriumi , Takao Saijo , Hiroshi Endo , Kuniaki Kamimura , Takanori Saito
发明人： Shiro Toriumi , Takao Saijo , Hiroshi Endo , Kuniaki Kamimura , Takanori Saito
IPC分类号： G03B21/11 , G03G15/28 , G03B13/28
CPC分类号： G03B21/118 , G03G15/28
摘要： The disclosure relates to an improved reading and printing apparatus which includes a carrier for holding a film in a flat state, a first positioning device for positioning the carrier at a screen projecting position for projecting the image of the film onto an observation screen, a second positioning device for positioning the carrier at a scanning starting position for scanning and exposing the image of the film, and a scanning device for scanning the carrier from the scanning starting position. By the above arrangement, the functions as the reader and printer are incorporated into the apparatus of compact size through elimination of wasteful space and time involved in the scanning of the carrier.
摘要翻译：本公开涉及一种改进的读取和打印装置，其包括用于保持平板状态的胶片的载体，用于将载体定位在用于将胶片的图像投影到观察屏幕上的屏幕突出位置的第一定位装置，第二定位装置，用于将载体定位在用于扫描和曝光胶片的图像的扫描开始位置;以及扫描装置，用于从扫描开始位置扫描载体。通过上述布置，通过消除涉及载体扫描的浪费空间和时间，将读取器和打印机的功能结合到紧凑尺寸的装置中。

3. 发明授权

US4616925A Reader printer 失效
标题翻译：读卡器打印机
公开(公告)号：US4616925A
公开(公告)日：1986-10-14
申请号：US683770
申请日：1984-12-19
申请人： Takao Saijo , Takanori Saito , Kuniaki Kamimura , Masafumi Fujita
发明人： Takao Saijo , Takanori Saito , Kuniaki Kamimura , Masafumi Fujita
IPC分类号： G03B27/32 , G03B21/11 , G03B27/34 , G03G15/04 , G03G15/22 , G03G15/26 , G03B13/24 , G03B13/26
CPC分类号： G03B21/118 , G03G15/223 , G03G15/26
摘要： The present invention is directed to a reader printer which handles an image of a microfilm held by an aperture card and maintained in such a manner that the microfilm center aligns with the center of card aperture. At the time of printing, the image of the microfilm is projected by scanning from a scanning start position that is same irrespective of film sizes on a photosensitive member, and the image thereon is transferred to a paper sheet which is provided by cutting the web supplied from rolled paper. The supply of the web is controlled by a first timer which starts simultaneously with start of scanning and the cutting of the web is controlled by a second timer which starts simultaneously with expiration of the first timer.
摘要翻译：本发明涉及一种读取器打印机，其处理由光圈卡保持的微缩胶片的图像，并且以这样的方式保持缩微胶片中心与卡孔的中心对准。在打印时，通过从与感光构件上的胶片尺寸无关的扫描开始位置进行扫描来投射微缩胶片的图像，并且将图像转印到通过切割所供纸的纸张而提供的纸张从卷纸。网的供应由第一计时器控制，第一定时器与扫描开始同时开始，并且由第一计时器同时启动的第二计时器来控制网的切割。

4. 发明授权

US09324591B2 Heat treatment apparatus and heat treatment method 有权
标题翻译：热处理设备及热处理方法
公开(公告)号：US09324591B2
公开(公告)日：2016-04-26
申请号：US13438234
申请日：2012-04-03
申请人： Koji Yoshii , Tatsuya Yamaguchi , Wenling Wang , Takanori Saito
发明人： Koji Yoshii , Tatsuya Yamaguchi , Wenling Wang , Takanori Saito
IPC分类号： F27D21/00 , H01L21/67
CPC分类号： H01L21/67109 , H01L21/67248
摘要： A heat treatment apparatus including: a processing container for processing wafers held in a boat; heaters for heating the processing container; and a control section for controlling the heaters. Heater temperature sensors are provided between the heaters and the processing container, in-container temperature sensors are provided in the processing container, and movable temperature sensors are provided in the boat. The temperature sensors are connected to a temperature estimation section. The temperature estimation section selects two of the three types of temperature sensors, e.g. the movable temperature sensors and the in-container temperature sensors, and determines the temperature of a wafer according to the following formula: T=T1×(1−α)+T2×α, α>1, where T1 and T2 represent detection temperatures of the selected temperature sensors, and α represents a mixing ratio.
摘要翻译：一种热处理设备，包括：处理容器，用于处理保存在船上的晶片; 用于加热处理容器的加热器; 以及用于控制加热器的控制部。加热器温度传感器设置在加热器和处理容器之间，容器内温度传感器设置在处理容器中，并且可移动的温度传感器设置在船上。温度传感器连接到温度估计部。温度估计部分选择三种类型的温度传感器中的两种，例如，可移动温度传感器和容器内温度传感器，并根据以下公式确定晶片的温度：T = T1×（1-α）+ T2×α，α> 1，其中T1和T2表示检测温度的选定温度传感器，α表示混合比。

5. 发明授权

US09273128B2 Pharmaceutical composition for treatment and/or prophylaxis of cancer 有权
标题翻译：用于治疗和/或预防癌症的药物组合物
公开(公告)号：US09273128B2
公开(公告)日：2016-03-01
申请号：US14236793
申请日：2012-08-03
申请人： Fumiyoshi Okano , Shinichi Kobayashi , Yoshitaka Minamida , Takanori Saito
发明人： Fumiyoshi Okano , Shinichi Kobayashi , Yoshitaka Minamida , Takanori Saito
IPC分类号： C07K16/30 , A61K39/395 , C07K16/18 , A61K45/06 , C07K16/28
CPC分类号： C07K16/18 , A61K39/39558 , A61K45/06 , C07K16/28 , C07K16/30 , C07K2317/24 , C07K2317/34 , C07K2317/73 , C07K2317/732
摘要： This invention provides an antibody targeting a cancer antigenic protein specifically expressed on the surface of cancer cells and use thereof as a therapeutic and/or preventive agent for cancer. More specifically, the present invention provides an antibody, or a fragment thereof which has immunological reactivity with a partial CAPRIN-1 polypeptide consisting of the amino acid sequence shown by SEQ ID NO: 5 or an amino acid sequence having 80% or higher sequence identity to the amino acid sequence, and a pharmaceutical composition for treatment and/or prevention of cancer comprising the same as an active ingredient.
摘要翻译：本发明提供靶向癌细胞表面特异性表达的癌抗原蛋白的抗体及其作为癌症治疗和/或预防剂的用途。更具体地，本发明提供了与由SEQ ID NO：5所示的氨基酸序列或具有80％以上序列同一性的氨基酸序列组成的部分CAPRIN-1多肽具有免疫学反应性的抗体或其片段和用于治疗和/或预防癌症的药物组合物，其包含其作为活性成分。

6. 发明授权

US09180188B2 Pharmaceutical composition for treatment and/or prophylaxis of cancer 有权
标题翻译：用于治疗和/或预防癌症的药物组合物
公开(公告)号：US09180188B2
公开(公告)日：2015-11-10
申请号：US14236795
申请日：2012-08-03
申请人： Shinichi Kobayashi , Fumiyoshi Okano , Yoshitaka Minamida , Takanori Saito
发明人： Shinichi Kobayashi , Fumiyoshi Okano , Yoshitaka Minamida , Takanori Saito
IPC分类号： C07K16/30 , A61K39/395 , A61K45/06 , C07K16/28 , A61K39/00
CPC分类号： A61K39/39558 , A61K45/06 , A61K2039/505 , C07K16/28 , C07K2317/24 , C07K2317/56 , C07K2317/732 , A61K2300/00
摘要： It is intended to identify a cancer antigenic protein specifically expressed on the surface of cancer cells and to provide an antibody targeting the antigenic protein and use of the antibody as a therapeutic and/or preventive agent for cancer. The present invention provides an antibody or a fragment thereof which has immunological reactivity with a CAPRIN-1 protein, the antibody comprising a heavy chain variable region comprising amino acid sequences of SEQ ID NOs: 5, 6, and 7 and a light chain variable region comprising amino acid sequences of SEQ ID NOs: 9, 10, and 11, and a pharmaceutical composition for treatment and/or prevention of cancer, comprising this antibody or fragment as an active ingredient.
摘要翻译：旨在鉴定在癌细胞表面上特异性表达的癌抗原蛋白，并提供靶向抗原蛋白的抗体和使用抗体作为癌症的治疗和/或预防剂。本发明提供了与CAPRIN-1蛋白具有免疫反应性的抗体或其片段，所述抗体包含包含SEQ ID NO：5,6和7的氨基酸序列的重链可变区和轻链可变区包含SEQ ID NO：9,10和11的氨基酸序列，和包含该抗体或片段作为活性成分的用于治疗和/或预防癌症的药物组合物。

7. 发明申请

US20140178373A1 PHARMACEUTICAL COMPOSITION FOR TREATMENT AND/OR PROPHYLAXIS OF CANCER 有权
公开(公告)号：US20140178373A1
公开(公告)日：2014-06-26
申请号：US14236665
申请日：2012-08-03
申请人： Shinichi Kobayashi , Fumiyoshi Okano , Takanori Saito
发明人： Shinichi Kobayashi , Fumiyoshi Okano , Takanori Saito
IPC分类号： C07K16/30 , A61K45/06 , A61K39/395
CPC分类号： C07K16/30 , A61K39/39558 , A61K45/06 , A61K47/6851 , A61K47/6855 , A61K47/6857 , A61K47/6861 , A61K47/6865 , A61K47/6869 , A61K2039/505 , C07K16/28 , C07K2317/24 , C07K2317/732
摘要： An object of the present invention is to prepare an antibody that targets CAPRIN-1 specifically expressed on the surface of cancer cells and is superior in antitumor activity to conventional antibodies and to provide use of the antibody as a therapeutic and/or preventive agent for cancer. The present invention provides use of an antibody targeting an identified cancer antigenic protein specifically expressed on the surface of cancer cells as a therapeutic and/or preventive agent for cancer, specifically, a pharmaceutical composition for treatment and/or prevention of cancer, comprising as an active ingredient an antibody or a fragment thereof which has immunological reactivity with a CAPRIN-1 protein, the antibody or the fragment thereof comprising a heavy chain variable region comprising amino acid sequences represented by SEQ ID NOs: 5, 6, and 7 and a light chain variable region comprising amino acid sequences represented by SEQ ID NOs: 9, 10, and 11.

8. 发明申请

US20120258415A1 HEAT TREATMENT APPARATUS AND HEAT TREATMENT METHOD 有权
标题翻译：热处理设备和热处理方法
公开(公告)号：US20120258415A1
公开(公告)日：2012-10-11
申请号：US13438234
申请日：2012-04-03
申请人： Koji YOSHII , Tatsuya Yamaguchi , Wenling Wang , Takanori Saito
发明人： Koji YOSHII , Tatsuya Yamaguchi , Wenling Wang , Takanori Saito
IPC分类号： F27D21/00 , F27D3/00
CPC分类号： H01L21/67109 , H01L21/67248
摘要： A heat treatment apparatus including: a processing container for processing wafers held in a boat; heaters for heating the processing container; and a control section for controlling the heaters. Heater temperature sensors are provided between the heaters and the processing container, in-container temperature sensors are provided in the processing container, and movable temperature sensors are provided in the boat. The temperature sensors are connected to a temperature estimation section. The temperature estimation section selects two of the three types of temperature sensors, e.g. the movable temperature sensors and the in-container temperature sensors, and determines the temperature of a wafer according to the following formula: T=T1×(1−α)+T2×α, α>1, where T1 and T2 represent detection temperatures of the selected temperature sensors, and α represents a mixing ratio.
摘要翻译：一种热处理设备，包括：处理容器，用于处理保存在船上的晶片; 用于加热处理容器的加热器; 以及用于控制加热器的控制部。加热器温度传感器设置在加热器和处理容器之间，容器内温度传感器设置在处理容器中，并且可移动的温度传感器设置在船上。温度传感器连接到温度估计部。温度估计部分选择三种类型的温度传感器中的两种，例如，可移动温度传感器和容器内温度传感器，并根据以下公式确定晶片的温度：T = T1×（1-α）+ T2×α，α> 1，其中T1和T2表示检测温度的选定温度传感器，α表示混合比。

9. 发明申请

US20110256144A1 PHARMACEUTICAL COMPOSITION FOR TREATMENT AND PREVENTION OF CANCERS 有权
标题翻译：用于治疗和预防癌症的药物组合物
公开(公告)号：US20110256144A1
公开(公告)日：2011-10-20
申请号：US13057709
申请日：2009-08-05
申请人： Fumiyoshi Okano , Takayoshi Ido , Takanori Saito , Shinichi Kobayashi
发明人： Fumiyoshi Okano , Takayoshi Ido , Takanori Saito , Shinichi Kobayashi
IPC分类号： A61K39/395 , A61P35/00 , A61P35/02 , C07K16/18
CPC分类号： C07K16/3015 , A61K39/39558 , A61K2039/505 , C07K16/30 , C07K16/3053 , C07K2317/24 , C07K2317/34 , C07K2317/565 , C07K2317/732 , C07K2317/734
摘要： The present invention relates to a pharmaceutical composition for treatment and/or prevention of cancer, which comprises, as an active ingredient, an antibody or fragment thereof having an immunological reactivity with a CAPRIN-1 protein or a fragment thereof comprising 7 or more consecutive amino acids.
摘要翻译：本发明涉及用于治疗和/或预防癌症的药物组合物，其包含与包含7个或更多个连续氨基酸的CAPRIN-1蛋白或其片段具有免疫学反应性的抗体或其片段作为活性成分酸。

10. 发明申请

US20100224614A1 Heat Treatment Apparatus, Heater, and Method for Manufacturing the Heater 有权
标题翻译：热处理装置，加热器及加热器制造方法
公开(公告)号：US20100224614A1
公开(公告)日：2010-09-09
申请号：US12223162
申请日：2007-02-07
申请人： Makoto Kobayashi , Kenichi Yamaga , Takanori Saito
发明人： Makoto Kobayashi , Kenichi Yamaga , Takanori Saito
IPC分类号： F27D11/00 , H05B3/02
CPC分类号： H01L21/67109 , H01L21/425 , Y10T29/49083
摘要： The present invention provides a heat treatment apparatus having a high degree of freedom of an outlet design and capable of adjusting the rate of a reduction in the temperature of each part of a heater without using an adjustment valve. The heat treatment apparatus having a simple flow path structure can be constructed with simplified sealing and a reduced cost.The heat treatment apparatus 1 includes a process chamber 2, a tubular heater 3, a heat exhaust system 25 and a cooling section 26. The process chamber 2 accommodates objects W to be placed in multiple stages and to be treated. A predetermined heat treatment is performed in the process chamber. The heater 3 surrounds an outer circumference of the process chamber 2 and heats the objects W to be treated. The heat exhaust system 25 is adapted to exhaust an atmosphere present in a space 24 existing between the heater 3 and the process chamber 2. The cooling section 26 is adapted to blow a cooling fluid into the space 24 to cool the atmosphere. The heater 3 includes a tubular heat insulator 17, a heat generating resistor 18 and an outer shell 20. The heat generating resistor 18 is provided on an inner circumference of the heat insulator 17. The outer shell 20 is provided on an outer circumference of the heat insulator 17. The cooling section 26 includes at least one annular flow path 28 and an outlet 29. The annular flow path 28 is arranged between the heat insulator 17 and the outer shell 20. The outlet 29 is provided in the heat insulator 17. The outlet 29 is arranged to ensure that the cooling fluid is blown out of the outlet 29 toward a vertical central axis of the heat insulator 17 or in a direction oblique to the direction toward vertical central axis of the heat insulator 17.
摘要翻译：本发明提供一种热处理装置，其具有出口设计的高自由度，并且能够调节加热器的每个部件的温度降低的速率而不使用调节阀。具有简单的流路结构的热处理装置可以以简单的密封和降低的成本构成。热处理设备1包括处理室2，管状加热器3，散热系统25和冷却部分26.处理室2容纳待放置的多个物体W并进行处理。在处理室中进行预定的热处理。加热器3围绕处理室2的外周并加热被处理物体W. 散热系统25适于排出存在于加热器3和处理室2之间的空间24中的气氛。冷却部分26适于将冷却流体吹入空间24以冷却大气。加热器3包括管状隔热件17，发热电阻18和外壳20.发热电阻18设置在隔热材料17的内周上。外壳20设置在绝热体17的外周。绝热体17.冷却部分26包括至少一个环形流动路径28和出口29.环形流路28设置在绝热体17和外壳20之间。出口29设置在绝热体17中。出口29布置成确保冷却流体从出口29朝向隔热件17的垂直中心轴线或者沿着与隔热件17的垂直中心轴方向倾斜的方向吹出。

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