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1. 发明授权

US5882594A Device and method for automatic sample pretreatment 失效
标题翻译：自动样品预处理的装置和方法
公开(公告)号：US5882594A
公开(公告)日：1999-03-16
申请号：US869597
申请日：1997-06-05
申请人： Seiji Kawaguchi , Toshiaki Kono , Hidechika Hayashi
发明人： Seiji Kawaguchi , Toshiaki Kono , Hidechika Hayashi
IPC分类号： G01N1/36 , G01N35/02 , G01N35/04 , G01N35/10
CPC分类号： G01N35/025 , G01N35/1083 , Y10T436/11 , Y10T436/113332 , Y10T436/114165 , Y10T436/114998
摘要： An automatic sample pretreatment device is provided which is capable of conducting a series of treatments or reactions from pretreatment to measurement automatically in a short time by employing a separate reaction system from the reaction system for measurement. The automatic sample pretreatment device comprises a sample rack, a pretreatment vessel and a measurement vessel, a liquid dispenser, a first vessel-transfer apparatus having a vessel holder for holding and transferring the vessels, a pretreatment vessel feeding apparatus for feeding the pretreatment vessel to the vessel holder of the first vessel transfer apparatus, a measurement vessel feeding apparatus for feeding the measurement vessel to the vessel holder of the first vessel-transfer apparatus, a vessel discarding hole for discarding the vessel after use, a second vessel-transfer device for transferring the used vessel held at the vessel holder of the first vessel-transfer apparatus to the vessel discarding hole, an incubator equipped with a measurement device for measuring a sample, and a third vessel-transfer device for transferring the vessel held by the vessel holder of the first vessel-transfer apparatus to the incubator.
摘要翻译：提供了一种自动样品预处理装置，其能够通过使用与反应系统进行测量的单独的反应系统，在短时间内进行一系列预处理或测量的处理或反应。自动样品预处理装置包括样品架，预处理容器和测量容器，液体分配器，具有用于保持和转移容器的容器保持器的第一容器转移装置，用于将预处理容器进给的预处理容器进料装置第一容器传送装置的容器保持器，用于将测量容器供给到第一容器转移装置的容器保持器的测量容器进给装置，使用后丢弃容器的容器废弃孔，用于将保持在第一容器传送装置的容器保持器处的二手容器转移到容器废弃孔，装备有用于测量样品的测量装置的培养箱和用于转移由容器保持器容纳的容器的第三容器转移装置的第一个血管转移装置。

2. 发明授权

US06108607A Method of rate calculation 失效
标题翻译：费率计算方法
公开(公告)号：US06108607A
公开(公告)日：2000-08-22
申请号：US899605
申请日：1997-07-24
申请人： Toshiaki Kono , Hidechika Hayashi , Tetsufumi Matsumoto
发明人： Toshiaki Kono , Hidechika Hayashi , Tetsufumi Matsumoto
IPC分类号： C12Q1/00 , C12M1/34
CPC分类号： C12Q1/00
摘要： A method of rate calculation in which, in connection with a reaction in which the substrate of an enzyme undergoes the action of the enzyme to be converted to a reaction product, a signal correlated to the concentration of the reaction product is measured at different points of time, those measured values obtained which exceed the upper limit preset in accordance with the detection limit of a detector to be used are excluded while selecting those measured values obtained at different points of time at least equal in number to the independent parameters of the approximating function and which are not greater than said upper limit and the measured values thus selected are weighted by a finite value to effect approximation by said function, provided that said finite value for weighting at least a portion of the measured values are changed continuously in accordance with the magnitudes of said specific measured values. This method is capable of calculating the rate of enzyme activity to accomplish precise quantification of a substance without impairing the continuity of a calibration curve even if measurements are conducted at discontinuous points of time over a measurement range where the rate will change under the influence of the concentrations of the substrate and the reaction product in the reaction mixture.
摘要翻译：一种速率计算方法，其中，在酶的底物经受酶转化为反应产物的作用的反应中，与反应产物的浓度相关的信号在不同点时间，排除所获得的超过根据所使用的检测器的检测限所预先设定的上限的测量值，同时选择在与近似函数的独立参数数量至少相等的不同时间点获得的测量值并且不大于所述上限，并且由此选择的测量值由有限值加权以实现所述函数的近似，条件是根据所述上限的至少一部分测量值的加权的所述有限值被连续地改变所述具体测量值的大小。该方法能够计算酶活性的速率来实现物质的精确定量，而不损害校准曲线的连续性，即使在不确定时间点进行测量，在测量范围内，速率将在反应混合物中底物和反应产物的浓度。

3. 发明申请

US20110060495A1 Method of predicting energy consumption, apparatus for predicting energy consumption, and terminal apparatus 有权
标题翻译：能耗预测方法，能耗预测装置及终端设备
公开(公告)号：US20110060495A1
公开(公告)日：2011-03-10
申请号：US12805846
申请日：2010-08-20
申请人： Toshiaki Kono , Takumi Fushiki
发明人： Toshiaki Kono , Takumi Fushiki
IPC分类号： G06F7/00 , G01C21/36
CPC分类号： G01C21/3469 , G08G1/096833
摘要： An object of the invention is to predict energy consumptions of a vehicle, using geographic characteristic values which are independent from particular driving patterns and vehicle parameters and unique to respective links. A navigation server predicts energies which are consumed when a vehicle runs on links. The navigation server calculates geographic characteristic values of respective links, the geography of the each link affecting the consumption energy with the geographic characteristic values, the calculation being based on energy consumptions collected from probe vehicles, and calculates predicted energy consumption of each link selected as a processing target, based on the geographic characteristic values. A navigation terminal obtains these predicted energy consumptions and performs route search with the obtained predicted energy consumptions as costs.
摘要翻译：本发明的一个目的是使用独立于特定驾驶模式和车辆参数并且对各个链路独特的地理特征值来预测车辆的能量消耗。导航服务器预测当车辆在链路上运行时消耗的能量。导航服务器计算各个链路的地理特征值，利用地理特征值影响消耗能量的每个链路的地理位置，计算基于从探测车辆收集的能量消耗，并且计算被选择为每个链路的每个链路的预测能量消耗处理目标，根据地理特征值。导航终端获得这些预测能量消耗，并以获得的预测能量消耗作为成本进行路线搜索。

4. 发明申请

US20080319645A1 ROUTE SEARCHING METHOD AND ROUTE SEARCHING SYSTEM 审中-公开
标题翻译：路由搜索方法和路由搜索系统
公开(公告)号：US20080319645A1
公开(公告)日：2008-12-25
申请号：US12143512
申请日：2008-06-20
申请人： Masatoshi Kumagai , Tomoaki Hiruta , Toshiaki Kono
发明人： Masatoshi Kumagai , Tomoaki Hiruta , Toshiaki Kono
IPC分类号： G01C21/34
CPC分类号： G01C21/3461 , G01C21/3484 , G08G1/01 , G08G1/096811 , G08G1/096844
摘要： It is an object of the present invention to provide a route searching which can reflect know-how such as easiness of running included in the probe car data in an entire route from departure place to destination.A center device detects main branch nodes from probe car data received from an in-vehicle terminal device by means of a main branch node detecting section. A probe car data dividing section divides the probe car data into probe segments by the main branch nodes. A route dividing section divides an initial route generated by a initial route generating section based on specified departure place and destination, and a derived route generating section substitutes probe segments for the divided routes so as to generate derived routes. The route selecting section scores the derived routes and select one so as to provide a recommended route in which know-how such as easiness of running included in the probe car data is reflected.
摘要翻译：本发明的目的是提供一种能够在从出发地到目的地的整个路线中反映包括在探测车数据中的运行容易性的专有技术的路线搜索。中央设备通过主分支节点检测部分从车载终端设备接收的探测车数据中检测主分支节点。探测车数据分割部通过主分支节点将探测车数据分割成探头段。路线分割部根据指定的出发地和目的地，对由初始路线生成部生成的初始路线进行分割，导出路线生成部将代入分割路线的探测段代入导出路线。路线选择部分对得到的路线进行评分，并选择一个路径，以提供其中反映了探测车辆数据中包括的运行容易性等专有技术的推荐路线。

5. 发明授权

US07138263B2 Endoglucanase enzyme NCE5 and cellulase preparations containing the same 有权
标题翻译：内切葡聚糖酶NCE5和含有相同的纤维素酶制剂
公开(公告)号：US07138263B2
公开(公告)日：2006-11-21
申请号：US10276779
申请日：2001-05-22
申请人： Koichiro Murashima , Naomi Sumida , Akitaka Nakane , Koji Yanai , Tomoko Nishimura , Jinichiro Koga , Takeshi Murakami , Toshiaki Kono
发明人： Koichiro Murashima , Naomi Sumida , Akitaka Nakane , Koji Yanai , Tomoko Nishimura , Jinichiro Koga , Takeshi Murakami , Toshiaki Kono
IPC分类号： C12N9/42 , C12N15/00 , D21B1/08 , C11D3/00 , C07H21/04
CPC分类号： C12N9/2437 , C11D3/38 , C11D3/38645 , C12Y302/01004 , D06M16/003 , D06P5/02 , D21C5/005 , D21C5/027 , D21C9/002 , Y02W30/648
摘要： There is provided an endoglucanase enzyme, which is useful for reducing fuzz of regenerated cellulose-containing fabrics, improving the touch and appearance, color clarification, localized variation in color, reducing stiffness and using it as components of a detergent, as well as deinking waste paper and improving freeness of paper pulp. A cDNA coding for the endoglucanase enzyme NCE5 was cloned and its DNA sequence and amino acid sequence derived from it were determined.
摘要翻译：提供了内切葡聚糖酶，其可用于减少再生含纤维素织物的绒毛，改善触感和外观，颜色澄清，颜色局部变化，降低刚度并将其用作洗涤剂的组分，以及脱墨废物纸张，提高纸浆的游离度。克隆编码内切葡聚糖酶NCE5的cDNA，并测定其DNA序列和氨基酸序列。

6. 发明授权

US06921655B1 Endoglucanases and cellulase preparations containing the same 有权
标题翻译：内切葡聚糖酶和含有其的纤维素酶制剂
公开(公告)号：US06921655B1
公开(公告)日：2005-07-26
申请号：US09807933
申请日：1999-10-25
申请人： Yuko Nakamura , Tatsuki Moriya , Yuko Baba , Koji Yanai , Naomi Sumida , Tomoko Nishimura , Kouichirou Murashima , Akitaka Nakane , Takashi Yaguchi , Jinichiro Koga , Takeshi Murakami , Toshiaki Kono
发明人： Yuko Nakamura , Tatsuki Moriya , Yuko Baba , Koji Yanai , Naomi Sumida , Tomoko Nishimura , Kouichirou Murashima , Akitaka Nakane , Takashi Yaguchi , Jinichiro Koga , Takeshi Murakami , Toshiaki Kono
IPC分类号： C11D3/386 , C12N9/42 , C12N15/56 , C12P21/06 , C07H21/04 , C12N9/00 , C12N9/24
CPC分类号： C12N9/2437 , C11D3/38645 , C12Y302/01004
摘要： It is an object of the present invention to provide enzymes that have high endoglucanase activity and yet exhibit high activity even under alkaline conditions, and genes encoding the same. The enzyme according to the invention has the following properties: a) exhibiting endoglucanase activity; and b) capable of completely removing fuzz from regenerated cellulose fabrics at a concentration of 1 mg of the protein/L or below. The enzyme of the invention having endoglucanase activity is a protein comprising the amino acid sequence as shown in SEQ ID NO: 1, 3, 5, 7, 9 or 11; a modified protein thereof exhibiting endoglucanase activity; or a homologue of the protein or the modified protein.
摘要翻译：本发明的目的是提供具有高内切葡聚糖酶活性并且即使在碱性条件下也表现出高活性的酶，以及编码该酶的基因。根据本发明的酶具有以下性质：a）显示内切葡聚糖酶活性; 和b）能够以1mg蛋白质/ L或以下的浓度从再生纤维素织物中完全除去绒毛。具有内切葡聚糖酶活性的本发明的酶是包含如SEQ ID NO：1,3,5,7,9或11所示的氨基酸序列的蛋白质; 其表现出内切葡聚糖酶活性的修饰蛋白质; 或蛋白质或修饰蛋白质的同系物。

7. 发明授权

US08694232B2 Method of predicting energy consumption, apparatus for predicting energy consumption, and terminal apparatus 有权
标题翻译：能耗预测方法，能耗预测装置及终端设备
公开(公告)号：US08694232B2
公开(公告)日：2014-04-08
申请号：US12805846
申请日：2010-08-20
申请人： Toshiaki Kono , Takumi Fushiki
发明人： Toshiaki Kono , Takumi Fushiki
IPC分类号： G06F19/00 , G01C21/00 , G08G1/123
CPC分类号： G01C21/3469 , G08G1/096833
摘要： An object of the invention is to predict energy consumptions of a vehicle, using geographic characteristic values which are independent from particular driving patterns and vehicle parameters and unique to respective links. A navigation server predicts energies which are consumed when a vehicle runs on links. The navigation server calculates geographic characteristic values of respective links, the geography of the each link affecting the consumption energy with the geographic characteristic values, the calculation being based on energy consumptions collected from probe vehicles, and calculates predicted energy consumption of each link selected as a processing target, based on the geographic characteristic values. A navigation terminal obtains these predicted energy consumptions and performs route search with the obtained predicted energy consumptions as costs.
摘要翻译：本发明的一个目的是使用独立于特定驾驶模式和车辆参数并且对各个链路独特的地理特征值来预测车辆的能量消耗。导航服务器预测当车辆在链路上运行时消耗的能量。导航服务器计算各个链路的地理特征值，利用地理特征值影响消耗能量的每个链路的地理位置，计算基于从探测车辆收集的能量消耗，并且计算被选择为每个链路的每个链路的预测能量消耗处理目标，根据地理特征值。导航终端获得这些预测能量消耗，并以获得的预测能量消耗作为成本进行路线搜索。

8. 发明申请

US20110060517A1 Car navigation system 有权
标题翻译：汽车导航系统
公开(公告)号：US20110060517A1
公开(公告)日：2011-03-10
申请号：US12805838
申请日：2010-08-20
申请人： Toshiaki Kono , Takumi Fushiki
发明人： Toshiaki Kono , Takumi Fushiki
IPC分类号： G06F19/00
CPC分类号： G01C21/3469
摘要： A car navigation system solves the problem that the emission test cycle fuel consumption rate indicates the energy consumption per unit distance covered following a prescribed emission test cycle procedure, and therefore, cannot produce a highly accurate prediction value reflecting the landform and the traffics along a route. So, the test cycle characteristic values independent of the vehicle model for vehicle energy consumption in a specified running condition are calculated, and the vehicle energy consumption parameter of the engine or the motor is estimated from the basic vehicle specifications such as the vehicle weight, the power supply type, the emission test cycle fuel consumption rate, the test cycle characteristic values in the emission test cycle and the vehicle characteristics. Using the basic vehicle specifications and the energy consumption parameter, the energy consumption is predicted taking the landform and traffics into consideration.
摘要翻译：汽车导航系统解决排放测试循环燃油消耗率表示按照规定的排放测试循环程序覆盖的每单位距离的能耗的问题，因此不能产生反映地形和沿着路线的交通的高度准确的预测值。因此，计算与指定运行条件下的车辆能量消耗的车辆模型无关的测试循环特性值，并且根据基本车辆规格来估计发动机或电动机的车辆能耗参数，例如车辆重量，电源类型，排放测试循环燃油消耗率，排放测试循环中的测试循环特征值和车辆特性。使用基本的车辆规格和能耗参数，考虑到地形和交通流量的能耗。

9. 发明申请

US20050143275A1 Endoglucanase nce5 and cellulase preparations containing the same 有权
标题翻译：内切葡聚糖酶nce5和含有相同的纤维素酶制剂
公开(公告)号：US20050143275A1
公开(公告)日：2005-06-30
申请号：US10276779
申请日：2001-05-22
申请人： Koichoro Murashima , Naomi Sumida , Akitaka Nakane , Koji Yanai , Tomoko Nishimura , Jinichiro Koga , Takeshi Murakami , Toshiaki Kono
发明人： Koichoro Murashima , Naomi Sumida , Akitaka Nakane , Koji Yanai , Tomoko Nishimura , Jinichiro Koga , Takeshi Murakami , Toshiaki Kono
IPC分类号： C11D3/38 , C11D3/386 , C12N1/15 , C12N1/19 , C12N9/42 , C12N15/56 , D06M16/00 , D06P5/02 , D21C5/00 , D21C5/02 , D21C9/00 , C07H21/04 , C12N1/16 , C12N1/18
CPC分类号： C12N9/2437 , C11D3/38 , C11D3/38645 , C12Y302/01004 , D06M16/003 , D06P5/02 , D21C5/005 , D21C5/027 , D21C9/002 , Y02W30/648
摘要： There is provided an endoglucanase enzyme, which is useful for reducing fuzz of regenerated cellulose-containing fabrics, improving the touch and appearance, color clarification, localized variation in color, reducing stiffness and using it as components of a detergent, as well as deinking waste paper and improving freeness of paper pulp. A cDNA coding for the endoglucanase enzyme NCE5 was cloned and its DNA sequence and amino acid sequence derived from it were determined.
摘要翻译：提供了内切葡聚糖酶，其可用于减少再生含纤维素织物的绒毛，改善触感和外观，颜色澄清，颜色局部变化，降低刚度并将其用作洗涤剂的组分，以及脱墨废物纸张，提高纸浆的游离度。克隆编码内切葡聚糖酶NCE5的cDNA，并测定其DNA序列和氨基酸序列。

10. 发明授权

US6159720A Enzyme endoglucanase and cellulase preparations containing the same 有权
标题翻译：酶内切葡聚糖酶和含有其的纤维素酶制剂
公开(公告)号：US6159720A
公开(公告)日：2000-12-12
申请号：US230222
申请日：1999-03-03
申请人： Kouichirou Murashima , Tatsuki Moriya , Toru Hamaya , Jinichiro Koga , Naomi Sumida , Kaoru Aoyagi , Takeshi Murakami , Toshiaki Kono
发明人： Kouichirou Murashima , Tatsuki Moriya , Toru Hamaya , Jinichiro Koga , Naomi Sumida , Kaoru Aoyagi , Takeshi Murakami , Toshiaki Kono
IPC分类号： C11D3/386 , C12N9/24 , C12N9/42 , C12N15/56 , C12S11/00 , D06M16/00 , D06P5/02 , D06P5/13 , D06P5/15
CPC分类号： C12N9/2437 , C11D3/38645 , C12Y302/01004 , D06M16/003 , D06M2101/06 , D06P5/02 , D06P5/137 , D06P5/158
摘要： A highly active cellulase suitable for use in a removal of nap of cellulose-containing fibers, a process for reducing cellulose-containing fibers and a process for decoloring denim-dyed cellulose-containing fibers, and its gene are provided. A novel cellulase NCE4 isolated from Humicola insolens is a highly active cellulase, and can be used for various treatments of cellulose-containing fibers.
摘要翻译： PCT No.PCT / JP97 / 02561 Sec。 371日期1999年3月3日 102（e）1999年3月3日PCT PCT 1997年7月24日PCT公布。出版物WO98 / 03640 日期1998年1月29日提供了适用于去除含纤维素纤维的绒毛的高活性纤维素酶，还原含纤维素纤维的方法和脱色含有纤维素的纤维素纤维的方法及其基因。从Humicola insolens分离的新型纤维素酶NCE4是一种高度活跃的纤维素酶，可用于纤维素纤维的各种处理。

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