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1. 发明申请

US20060034910A1 Pharmaceutical composition for extended release of phenytoin sodium 审中-公开
标题翻译：延缓苯妥英钠释放的药物组合物
公开(公告)号：US20060034910A1
公开(公告)日：2006-02-16
申请号：US11199169
申请日：2005-08-09
申请人： Sanjay Patel , Gour Mukherji , Jayadev Patil , Sidharth Mate
发明人： Sanjay Patel , Gour Mukherji , Jayadev Patil , Sidharth Mate
IPC分类号： A61K9/48 , A61K9/26
CPC分类号： A61K9/1617 , A61K9/1611 , A61K9/1652
摘要： The present invention provides an oral extended release solid pharmaceutical composition of phenytoin sodium or its pharmaceutically acceptable derivative thereof and the process of manufacturing the same the said extended release oral solid pharmaceutical composition comprising of at least one suitable pharmaceutically acceptable excipient alongwith phenytoin sodium. The said extended release oral solid pharmaceutical composition is manufactured by blending phenytoin sodium with at least one suitable pharmaceutically acceptable excipient and granulating the blend optionally using at least one suitable binder dissolved in an organic solvent or mixture of solvents.
摘要翻译：本发明提供苯妥英钠或其药学上可接受的衍生物的口服延长释放固体药物组合物及其制备方法，所述延长释放口服固体药物组合物包含至少一种合适的药学上可接受的赋形剂以及苯妥英钠。所述延长释放的口服固体药物组合物通过将苯妥英钠与至少一种合适的药学上可接受的赋形剂混合并且任选地使用溶解在有机溶剂或溶剂混合物中的至少一种合适的粘合剂来制备所述共混物来制造。

2. 发明授权

US09223721B2 Embedded processor with virtualized security controls using guest identifications, a common kernel address space and operational permissions 有权
标题翻译：嵌入式处理器采用虚拟化安全控制，使用客户端标识，通用内核地址空间和操作权限
公开(公告)号：US09223721B2
公开(公告)日：2015-12-29
申请号：US13603280
申请日：2012-09-04
申请人： Sanjay Patel , Ranjit Joseph Rozario
发明人： Sanjay Patel , Ranjit Joseph Rozario
IPC分类号： G06F12/10 , G06F12/14
CPC分类号： G06F9/45558 , G06F12/1036 , G06F12/109 , G06F12/145 , G06F12/1475 , G06F2009/45587
摘要： A method includes assigning unique guest identifications to different guests, specifying an address region and permissions for the different guests and controlling a guest jump from one physical memory segment to a second physical memory segment through operational permissions defined in a root memory management unit that supports guest isolation and protection.
摘要翻译：一种方法包括为不同的访客分配唯一的访客标识，为不同的客人指定地址区域和权限，并通过在支持访客的根内存管理单元中定义的操作权限来控制来宾从一个物理内存段跳转到第二个物理内存段隔离和保护。

3. 发明授权

US09095503B2 System and method for biphasic transdermal iontophreotic delivery of therapeutic agents 有权
标题翻译：用于治疗剂的双相透皮离子电渗递送的系统和方法
公开(公告)号：US09095503B2
公开(公告)日：2015-08-04
申请号：US13430662
申请日：2012-03-26
申请人： Mir Imran , Mir Hashim , Glen McLaughlin , Huma Arastu , Rekha Vaidyanathan , Joel Harris , Radhika Korupolu , Andrew Mangogna , Chang Ong , Sanjay Patel , Lu Wang , Timothy Williams
发明人： Mir Imran , Mir Hashim , Glen McLaughlin , Huma Arastu , Rekha Vaidyanathan , Joel Harris , Radhika Korupolu , Andrew Mangogna , Chang Ong , Sanjay Patel , Lu Wang , Timothy Williams
IPC分类号： A61N1/30 , A61K9/00 , A61N1/04 , A61K31/4178 , A61K31/4468 , A61K31/454 , A61K31/5415 , A61N1/32
CPC分类号： A61N1/325 , A61K9/0009 , A61K9/0014 , A61K31/4178 , A61K31/4468 , A61K31/454 , A61K31/5415 , A61N1/0436 , A61N1/044 , A61N1/0448 , A61N1/30 , A61N1/303
摘要： Various embodiments provide methods and systems for the biphasic iontophoretic transdermal delivery of therapeutic agents. An embodiment of a method for such delivery comprises positioning at least one electrode assembly in electrical communication with a patient's skin. The assembly includes a solution comprising a therapeutic agent which passively diffuses into the skin. A dose of agent is delivered from the assembly into the skin during a first period using a first current having a characteristic e.g., polarity and magnitude, to repel the agent out of the assembly. During a second period, a second current having a characteristic to attract the agent is used to retain the agent in the assembly such that delivery of agent into skin is minimized. A dose of agent may be delivered on demand by an input from the patient. Embodiments may be used for delivery of agents which cause adverse effects from unwanted passive diffusion.
摘要翻译：各种实施方案提供了用于治疗剂的双相离子电渗透皮递送的方法和系统。用于这种传送的方法的实施例包括将至少一个电极组件定位成与患者的皮肤电连通。组合件包括包含被动地扩散入皮肤的治疗剂的溶液。使用具有例如极性和大小的特性的第一电流，在第一时段期间，将剂量的药剂从组合物输送到皮肤中，以将药剂排斥出组合体。在第二时段期间，使用具有吸引剂的特性的第二电流将试剂保持在组合中，使得药剂递送到皮肤中最小化。可以根据患者的输入要求递送剂量。实施方案可以用于递送由不希望的被动扩散引起不利影响的试剂。

4. 发明授权

US09086906B2 Apparatus and method for guest and root register sharing in a virtual machine 有权
标题翻译：在虚拟机中访客和根寄存器共享的装置和方法
公开(公告)号：US09086906B2
公开(公告)日：2015-07-21
申请号：US13436654
申请日：2012-03-30
申请人： Sanjay Patel , Ranjit Joseph Rozario
发明人： Sanjay Patel , Ranjit Joseph Rozario
IPC分类号： G06F9/455
CPC分类号： G06F9/4555
摘要： A computer readable storage medium includes executable instructions to define a processor with guest mode control registers supporting guest mode operating behavior defined by guest context specified in the guest mode control registers. The guest mode control registers include a control bit to specify a guest access blocked register state and a shared register state. Root mode control registers support root mode operating behavior defined by root context specified in the root mode control registers. The root mode control registers include control bits to enable replicated register state access and shared register state access. The guest context and the root context support virtualization of hardware resources such that multiple operating systems supporting multiple applications are executed by the hardware resources.
摘要翻译：计算机可读存储介质包括可执行指令，以定义具有访客模式控制寄存器的处理器，所述访客模式控制寄存器支持由访客模式控制寄存器中指定的访客上下文定访客模式控制寄存器包括一个控制位，用于指定访客阻止寄存器状态和共享寄存器状态。根模式控制寄存器支持在根模式控制寄存器中指定的根上下文定义的根模式操作行为。根模式控制寄存器包括用于启用复制寄存器状态访问和共享寄存器状态访问的控制位。访客环境和根本环境支持硬件资源的虚拟化，使得支持多个应用的多个操作系统由硬件资源执行。

5. 发明授权

US08524720B2 Substituted N-(pyrazol-5-yl)-pyrrolo[3,2-D]pyrimidin-4-amine useful as protein kinase inhibitors 有权
标题翻译：用作蛋白激酶抑制剂的取代的N-（吡唑-5-基） - 吡咯并[3,2-D]嘧啶-4-胺
公开(公告)号：US08524720B2
公开(公告)日：2013-09-03
申请号：US12651639
申请日：2010-01-04
申请人： David Bebbington , Hayley Binch , Ronald Knegtel , Julian M.C. Golec , Sanjay Patel , Jean-Damien Charrier , David Kay , Robert Davies , Pan Li , Marion Wannamaker , Cornelia Forster , Albert Pierce
发明人： David Bebbington , Hayley Binch , Ronald Knegtel , Julian M.C. Golec , Sanjay Patel , Jean-Damien Charrier , David Kay , Robert Davies , Pan Li , Marion Wannamaker , Cornelia Forster , Albert Pierce
IPC分类号： C07D487/04 , A61K31/519 , A61P35/00 , A61P25/28 , A61P3/10
CPC分类号： C07D401/14 , C07D231/12 , C07D233/56 , C07D249/08 , C07D401/12 , C07D403/12 , C07D403/14 , C07D405/14 , C07D407/14 , C07D409/14 , C07D417/14 , C07D471/04 , C07D473/16 , C07D487/04 , C07D491/04 , C07D491/10 , C07D493/04 , C07D495/04 , C07D498/04 , C07D513/04
摘要： This invention describes novel pyrazole compounds of formula IV: wherein Ring D is a 5-7 membered monocyclic ring or 8-10 membered bicyclic ring selected from aryl, heteroaryl, heterocyclyl or carbocyclyl; Rx and Ry are independently selected from T-R3, or taken together with their intervening atoms to form a fused, unsaturated or partially unsaturated, 5-8 membered ring having 1-3 ring heteroatoms selected from oxygen, sulfur, or nitrogen; and R2, R2′, T, and R3 are as described in the specification. The compounds are useful as protein kinase inhibitors, especially as inhibitors of aurora-2 and GSK-3, for treating diseases such as cancer, diabetes and Alzheimer's disease.
摘要翻译：本发明描述了式IV的新型吡唑化合物：其中环D是5-7元单环或选自芳基，杂芳基，杂环基或碳环基的8-10元双环; R x和R y独立地选自T-R 3，或与它们的插入原子一起形成具有1-3个选自氧，硫或氮的环杂原子的稠合的，不饱和的或部分不饱和的5-8元环; R2，R2'，T和R3如说明书中所述。这些化合物可用作蛋白激酶抑制剂，特别是作为用于治疗诸如癌症，糖尿病和阿尔茨海默病的疾病的极光-2和GSK-3的抑制剂。

6. 发明申请

US20120177700A1 Nanonized Iron Compositions and Methods of Use Thereof 审中-公开
标题翻译：纳米铁组合物及其使用方法
公开(公告)号：US20120177700A1
公开(公告)日：2012-07-12
申请号：US13338210
申请日：2011-12-27
申请人： Mir A. Imran , Mir Hashim , Lu Wang , Sanjay Patel , Joel M. Harris , Phil Morgan
发明人： Mir A. Imran , Mir Hashim , Lu Wang , Sanjay Patel , Joel M. Harris , Phil Morgan
IPC分类号： A61K9/00 , A61K33/42 , B82Y5/00
CPC分类号： A61K9/14 , A61K33/26
摘要： Embodiments of the invention provide nanonized iron compositions for treatment of iron deficiency such as iron deficiency anemia. Many embodiments provide nanonized iron compositions which are sized to minimize adverse reaction such as immune response, adverse GI reaction and allergic reaction to iron compound included in the composition. The nanonized iron compositions can be used in a variety of drug delivery forms, including an oral dosage form, a transdermal patch, in an intravenous solution or in a dialysate for treatment of a patient with chronic kidney disease (CKD). Embodiments of the invention also provide methods of using the nanonized iron compositions for the treatment of iron deficiency in a patient in need thereof including patients with iron deficiency anemia and CKD.
摘要翻译：本发明的实施方案提供了用于治疗铁缺乏症（例如缺铁性贫血）的纳米铁组合物。许多实施方案提供纳米级铁组合物，其尺寸设定成使包括在组合物中的铁化合物的不良反应如免疫应答，不良GI反应和过敏反应最小化。纳米铁组合物可以以各种药物递送形式使用，包括口服剂型，透皮贴剂，静脉内溶液或用于治疗慢性肾脏病（CKD）患者的透析液。本发明的实施方案还提供了使用纳米铁组合物治疗需要其的患者缺铁的方法，包括缺铁性贫血和CKD患者。

7. 发明授权

US08195883B2 Resource sharing to reduce implementation costs in a multicore processor 有权
标题翻译：资源共享以降低多核处理器中的实施成本
公开(公告)号：US08195883B2
公开(公告)日：2012-06-05
申请号：US12694877
申请日：2010-01-27
申请人： Prashant Jain , Yoganand Chillarige , Sandip Das , Shukur Moulali Pathan , Srinivasan R. Iyengar , Sanjay Patel
发明人： Prashant Jain , Yoganand Chillarige , Sandip Das , Shukur Moulali Pathan , Srinivasan R. Iyengar , Sanjay Patel
IPC分类号： G06F13/00
CPC分类号： G06F12/0811 , G06F12/0813
摘要： A processor may include several processor cores, each including a respective higher-level cache; a lower-level cache including several tag units each including several controllers, where each controller corresponds to a respective cache bank configured to store data, and where the controllers are concurrently operable to access their respective cache banks; and an interconnect network configured to convey data between the cores and the lower-level cache. The controllers may share access to an interconnect egress port coupled to the interconnect network, and may generate multiple concurrent requests to convey data via the shared port, where each of the requests is destined for a corresponding core, and where a datapath width of the port is less than a combined width of the multiple requests. The given tag unit may arbitrate among the controllers for access to the shared port, such that the requests are transmitted to corresponding cores serially rather than concurrently.
摘要翻译：处理器可以包括几个处理器核心，每个处理器核心包括相应的更高级别的高速缓存; 包括几个标签单元的低级缓存，每个标签单元包括多个控制器，其中每个控制器对应于被配置为存储数据的相应缓存组，并且其中控制器同时可操作以访问其各自的高速缓存存储体; 以及被配置为在所述核和所述下级缓存之间传送数据的互连网络。控制器可以共享对耦合到互连网络的互连出口端口的访问，并且可以生成多个并发请求以经由共享端口传送数据，其中每个请求去往相应的核心，并且其中端口的数据路径宽度小于多个请求的组合宽度。给定标签单元可以在控制器之间仲裁以访问共享端口，使得请求被串行地发送到相应的核心而不是同时发送。

8. 发明授权

US08117896B2 Preconcentrators and methods of making and using the same 失效
公开(公告)号：US08117896B2
公开(公告)日：2012-02-21
申请号：US11836736
申请日：2007-08-09
申请人： Jonathan Day Lucas , Manna Leon Warburton , Todd Mlsna , Sanjay Patel , Stephen Terrence Hobson
发明人： Jonathan Day Lucas , Manna Leon Warburton , Todd Mlsna , Sanjay Patel , Stephen Terrence Hobson
IPC分类号： G01N30/08
CPC分类号： G01N30/08 , G01N2030/085 , G01N2030/126
摘要： Apparatus, systems and methods are described for preconcentrators, chemical sensing systems and gas chromatographs. A preconcentrator is described that comprises a hollow enclosure containing a sorbent material. The enclosure may be a capillary tube that can be formed in to a desired shape and that may be heated. Heating may be accomplished by passing an electrical current through the capillary or other hollow enclosure form. The sorbent material can be a liquid, a solid, a porous ceramic material and/or a chemiselective polymer. The sorbent material can be coated to the inner wall of the enclosure. The hollow enclosure may be maintained in an insulated chamber. The preconcentrator acts to concentrate a vapor passed through the preconcentrator to a chemical sensing array that can detect chemicals present in the vapor. A gas passed through the hollow enclosure can provide a chemically concentrated input to a chromatographic column.

9. 发明授权

US07672553B2 High speed semiconductor optical modulator 有权
标题翻译：高速半导体光调制器
公开(公告)号：US07672553B2
公开(公告)日：2010-03-02
申请号：US11681070
申请日：2007-03-01
申请人： Douglas M. Gill , Christopher D. W. Jones , Sanjay Patel , Mahmoud Rasras , Nils G. Weimann
发明人： Douglas M. Gill , Christopher D. W. Jones , Sanjay Patel , Mahmoud Rasras , Nils G. Weimann
IPC分类号： G02B6/26
CPC分类号： G02F1/025 , G02F2001/0152
摘要： The present invention provides an optical waveguide modulator. In one embodiment, the optical waveguide modulator includes a semiconductor planar optical waveguide core and doped semiconductor connecting paths located adjacent opposite sides of the core and capable of applying a voltage across the core. The optical waveguide core and connecting paths form a structure having back-to-back PN semiconductor junctions. In another embodiment, the optical waveguide modulator includes a semiconductor optical waveguide core including a ridge portion wherein the ridge portion has at least one PN semiconductor junction located therein. The optical waveguide modulator also includes one or more doped semiconductor connecting paths located laterally adjacent the ridge portion and capable of applying a voltage to the ridge portion.
摘要翻译：本发明提供一种光波导调制器。在一个实施例中，光波导调制器包括半导体平面光波导芯和与芯相邻的相邻侧面的掺杂半导体连接路径，并能跨越芯施加电压。光波导芯和连接路径形成具有背对背PN半导体结的结构。在另一个实施例中，光波导调制器包括半导体光波导芯，其包括脊部，其中脊部具有位于其中的至少一个PN半导体结。光波导调制器还包括一个或多个掺杂的半导体连接路径，其位于横向邻近脊部分并且能够向脊部分施加电压。

10. 发明申请

US20090161113A1 INTEGRATED OPTOELECTRONIC SYSTEM FOR AUTOMATIC CALIBRATION OF AN OPTICAL DEVICE 审中-公开
标题翻译：用于自动校准光学器件的集成光电系统
公开(公告)号：US20090161113A1
公开(公告)日：2009-06-25
申请号：US11960017
申请日：2007-12-19
申请人： Young-Kai Chen , Sanjay Patel , Mahmoud Rasras , Kun-Yii Tu
发明人： Young-Kai Chen , Sanjay Patel , Mahmoud Rasras , Kun-Yii Tu
IPC分类号： G01B9/02
CPC分类号： G02B6/12007 , G02B6/29353 , G02B6/29395 , G02F1/0147 , G02F2203/15
摘要： An apparatus and method for automated calibration of an optical device are disclosed. The apparatus is an integrated optoelectronic system that includes input and output optical waveguides, a tunable optical device, an optical source, an optical detector, and an electronic controller formed on a single substrate. The tunable optical device has one or more tuning elements for varying one or more characteristics of the device. The optical source is coupled to the input waveguide for providing a calibration signal to the device. The optical detector is coupled to the output optical waveguide for measuring an intensity of the optical signal output by the device in response to receiving the calibration signal. The electronic controller is configured to perform a calibration of the device by varying a parameter of each tuning element and to receive intensity measurements of the optical signal output by the device as a function of the varied parameter.
摘要翻译：公开了一种用于光学装置的自动校准的装置和方法。该装置是集成光电系统，其包括输入和输出光波导，可调谐光学装置，光源，光学检测器和形成在单个基板上的电子控制器。可调光学器件具有用于改变器件的一个或多个特性的一个或多个调谐元件。光源耦合到输入波导，以向设备提供校准信号。光学检测器耦合到输出光波导，用于响应于接收到校准信号来测量器件输出的光信号的强度。电子控制器被配置为通过改变每个调谐元件的参数来执行设备的校准，并且根据变化的参数来接收设备输出的光信号的强度测量值。

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