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    • 5. 发明申请
    • GENOTYPING OF BOVINE PAPILLOMAVIRUS GENOTYPES
    • 牛血清病毒基因组遗传学研究
    • US20120107797A1
    • 2012-05-03
    • US13256930
    • 2010-03-17
    • Markus SchmittMartin Müller
    • Markus SchmittMartin Müller
    • C12Q1/70
    • C12Q1/708
    • The present invention is concerned with the provision of diagnostic means and methods. Specifically, it relates to a composition comprising oligonucleotides selected from at least two different groups of oligonucleotides, said groups comprising at least one pair of oligonucleotides being capable of specifically amplifying polynucleotides comprised by a Bovine Papillomavirus (BPV), said BPV being selected from the group consisting of BPV-1, BPV-2, BPV-3, BPV-4, BPV-5, BPV-6, BPV-7, BPV-8, BPV-9, BPV-10, and BAPV-11 as well as uses based on said composition and kits comprising it. Moreover, contemplated is a method for the simultaneous detection and/or identification of BPV types in a sample.
    • 本发明涉及提供诊断手段和方法。 具体地,本发明涉及包含寡核苷酸的组合物,所述寡核苷酸选自至少两个不同的寡核苷酸组,所述组包含至少一对能够特异性扩增由牛乳头瘤病毒(BPV)组成的多核苷酸的寡核苷酸,所述BPV选自组 由BPV-1,BPV-2,BPV-3,BPV-4,BPV-5,BPV-6,BPV-7,BPV-8,BPV-9,BPV-10和BAPV-11组成, 基于所述组合物和包含它的试剂盒。 此外,预期的是同时检测和/或识别样品中BPV类型的方法。
    • 7. 发明申请
    • Lateral MISFET and method for fabricating it
    • 侧面MISFET及其制造方法
    • US20060261384A1
    • 2006-11-23
    • US11276782
    • 2006-03-14
    • Michael RuebMarkus SchmittCarolin TolksdorfUwe WahlArmin Willmeroth
    • Michael RuebMarkus SchmittCarolin TolksdorfUwe WahlArmin Willmeroth
    • H01L29/76
    • H01L29/782H01L29/0619H01L29/0696H01L29/7825
    • A lateral MISFET having a semiconductor body has a doped semiconductor substrate of a first conduction type and an epitaxial layer of a second conduction type, which is complementary to the first conduction type, the epitaxial layer being provided on the semiconductor substrate. This MISFET has, on the top side of the semiconductor body, a drain, a source, and a gate electrode with gate insulator. A semiconductor zone of the first conduction type is embedded in the epitaxial layer in a manner adjoining the gate insulator, a drift zone of the second conduction type being arranged between the semiconductor zone and the drain electrode in the epitaxial layer. The drift zone has pillar-type regions which are arranged in rows and columns and whose boundary layers have a metal layer which in each case forms a Schottky contact with the material of the drift zone.
    • 具有半导体本体的横向MISFET具有第一导电类型的掺杂半导体衬底和与第一导电类型互补的第二导电类型的外延层,外延层设置在半导体衬底上。 该MISFET在半导体本体的顶侧具有漏极,源极和具有栅极绝缘体的栅电极。 第一导电类型的半导体区域以与栅极绝缘体相邻的方式嵌入在外延层中,第二导电类型的漂移区被布置在外延层中的半导体区域和漏极之间。 漂移区具有排列成行和列的柱状区域,其边界层具有金属层,其在每种情况下与漂移区的材料形成肖特基接触。
    • 10. 发明申请
    • COMPOSITION COMPRISING AN OLIGONUCLEOTIDE MIXTURE FOR THE DETECTION OF CONTAMINATIONS IN CELL CULTURES
    • 包含寡核苷酸混合物的组合物用于检测细胞培养物中的污染
    • US20110091885A1
    • 2011-04-21
    • US12920095
    • 2009-03-05
    • Markus SchmittMichael Pawlita
    • Markus SchmittMichael Pawlita
    • C12Q1/68
    • C12Q1/689C12Q1/686C12Q1/6881C12Q1/701C12Q1/702C12Q1/705C12Q2600/16
    • The present invention relates to a method for determining contaminations in a cell culture sample comprising the steps of: a) contacting a sample of a cell culture suspected to comprise contaminations with a composition comprising oligonucleotides under conditions which allow for amplification of polynucleotides, wherein said oligonucleotides comprise oligonucleotides of at least three different groups of oligonucleotides, and b) determining the contaminations based on the amplified polynucleotides obtained by using the oligonucleotide groups of step (a). Moreover, the invention relates to a composition comprising an oligonucleotide mixture. Further encompassed by the present invention is a composition comprising a probe oligonucleotide mixture. Finally, the present invention also relates to kits comprising said oligonucleotide mixtures.
    • 本发明涉及一种用于确定细胞培养物样品中污染物的方法,包括以下步骤:a)在允许扩增多核苷酸的条件下,将怀疑含有污染物的细胞培养物样品与包含寡核苷酸的组合物接触,其中所述寡核苷酸 包含至少三种不同组寡核苷酸的寡核苷酸,和b)基于通过使用步骤(a)的寡核苷酸组获得的扩增多核苷酸来测定污染物。 此外,本发明涉及包含寡核苷酸混合物的组合物。 本发明进一步包括的是包含探针寡核苷酸混合物的组合物。 最后,本发明还涉及包含所述寡核苷酸混合物的试剂盒。