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1. 发明授权

US5166990A Multiple optical fiber event sensor and method of manufacture 失效
标题翻译：多光纤事件传感器及其制造方法
公开(公告)号：US5166990A
公开(公告)日：1992-11-24
申请号：US751818
申请日：1991-08-29
申请人： Samuel D. Riccitelli , Thomas A. Shern , Richard Homick , Alan Nelson , Charles S. Bankert , Henry K. Hui
发明人： Samuel D. Riccitelli , Thomas A. Shern , Richard Homick , Alan Nelson , Charles S. Bankert , Henry K. Hui
IPC分类号： A61B5/00 , G01N21/77 , G01N21/78
CPC分类号： A61B5/14539 , A61B5/0084 , A61B5/1459 , G01N21/7703 , G01N2021/773 , G01N21/783
摘要： The multiple optical fiber event sensor apparatus includes a semipermeable generally cylindrical shaft, one or more optical fiber gas sensor modules within the shaft, and an optical fiber pH sensor module extending beyond the distal end of the shaft, with the sensor modules arranged in an axially staggered relationship. The shaft contains a potting matrix for axially fixing the position of the optical fibers, and includes a gas permeable portion surrounding the one or more gas sensor modules, and a hydrophilic portion covering at least part of the pH sensor module. A hemodynamically shaped, rounded distal end is also provided on the distal end of the shaft. The device provides for a multiplicity of individual sensors incorporated in a single shaft which minimizes cross-interference and thrombus formation when used as an intravascular multi-sensor.
摘要翻译：多光纤事件传感器设备包括半透明的圆柱形轴，轴内的一个或多个光纤气体传感器模块，以及延伸超过轴远端的光纤pH传感器模块，传感器模块布置在轴向交错的关系轴包含用于轴向固定光纤位置的灌封基体，并且包括围绕一个或多个气体传感器模块的透气部分和覆盖至少部分pH传感器模块的亲水部分。血液动力学形状的圆形远端也设置在轴的远端上。该装置提供多个独立的传感器，其结合在单个轴中，当用作血管内多传感器时，可最大限度地减少交叉干扰和血栓形成。

2. 发明授权

US5246859A Method of stabilizing a carbon dioxide sensor 失效
标题翻译：稳定二氧化碳传感器的方法
公开(公告)号：US5246859A
公开(公告)日：1993-09-21
申请号：US888550
申请日：1992-05-22
申请人： Alan Nelson , Henry K. Hui , Monte Bennett , Soonkap Hahn , Charles S. Bankert , Jeffrey T. Jackson
发明人： Alan Nelson , Henry K. Hui , Monte Bennett , Soonkap Hahn , Charles S. Bankert , Jeffrey T. Jackson
IPC分类号： A61B5/145 , A61B5/1459 , G01N31/22 , G01N33/49 , G01N33/84
CPC分类号： G01N33/84 , G01N31/223 , Y10T436/102499 , Y10T436/108331 , Y10T436/20 , Y10T436/204998 , Y10T436/255
摘要： The method of stabilizing a carbon dioxide sensor involves formulation of a bicarbonate buffer solution in the sensor with a bicarbonate ion concentration of from about 100 mM to about 200 mM bicarbonate. The method also involves treatment of the sensor to reduce the instability that may occur in carbon dioxide sensors when such sensors are exposed to either very low or very high carbon dioxide levels for extended periods of time. The sensor is treated by exposing the sensor to an aqueous solution containing at least 2 weight percent carbon dioxide, for from several days to several months. The solution may be prepared in advance, or may be dynamically infused with carbon dioxide to provide the desired carbon dioxide content.
摘要翻译：稳定二氧化碳传感器的方法包括在传感器中配制碳酸氢盐缓冲溶液，碳酸氢根离子浓度为约100mM至约200mM碳酸氢盐。该方法还涉及传感器的处理，以减少二氧化碳传感器当这种传感器长时间暴露于非常低或非常高的二氧化碳水平时可能发生的不稳定性。通过将传感器暴露于含有至少2重量％二氧化碳的水溶液中来处理传感器，持续数天至数月。该溶液可以预先制备，或者可以动态地注入二氧化碳以提供所需的二氧化碳含量。

3. 发明授权

US5204265A Method of stabilizing a carbon dioxide sensor 失效
标题翻译：稳定二氧化碳传感器的方法
公开(公告)号：US5204265A
公开(公告)日：1993-04-20
申请号：US933884
申请日：1992-08-21
申请人： Alan Nelson , Henry K. Hui , Monte Bennett , Soonkap Hahn , Charles S. Bankert
发明人： Alan Nelson , Henry K. Hui , Monte Bennett , Soonkap Hahn , Charles S. Bankert
IPC分类号： A61B5/00 , G01N21/77 , G01N33/00
CPC分类号： G01N21/7703 , A61B5/1455 , A61B5/1495 , G01N33/0006 , G01N2201/127 , Y10T436/10 , Y10T436/102499
摘要： The method of stabilizing a carbon dioxide sensor involves treatment of the sensor to reduce the instability that may occur in carbon dioxide sensors when such sensors are exposed to either very low or very high carbon dioxide levels for extended periods of time. This is accomplished by storing the sensor in an aqueous solution containing at least 2 weight percent carbon dioxide, for from several days to several months. The solution may be prepared in advance, or may be dynamically infused with carbon dioxide to provide the desired carbon dioxide content.
摘要翻译：稳定二氧化碳传感器的方法包括处理传感器以减少在二氧化碳传感器中长时间暴露于非常低或非常高的二氧化碳水平时可能发生的不稳定性。这通过将传感器储存在含有至少2重量％二氧化碳的水溶液中来实现，从几天到几个月。该溶液可以预先制备，或者可以动态地注入二氧化碳以提供所需的二氧化碳含量。

4. 发明授权

US5326531A CO.sub.2 sensor using a hydrophilic polyurethane matrix and process for manufacturing 失效
标题翻译：使用亲水性聚氨酯基质的二氧化碳传感器和制造方法
公开(公告)号：US5326531A
公开(公告)日：1994-07-05
申请号：US989102
申请日：1992-12-11
申请人： Soonkap Hahn , Alan Nelson , Monte Bennett , Henry K. Hui
发明人： Soonkap Hahn , Alan Nelson , Monte Bennett , Henry K. Hui
IPC分类号： A61B5/00 , G01N21/64 , G01N21/77 , G01N21/00 , G01N33/50
CPC分类号： G01N21/643 , A61B5/1455 , G01N21/7703 , G01N2021/772 , G01N2021/7786
摘要： The carbon dioxide sensor includes a CO.sub.2 sensing matrix formed from a hydrophilic, gas permeable, cross-linked polyurethane. The polyurethane matrix is formed from a polyurethane pre-polymer mixture which cross links when mixed with an aqueous carbon dioxide buffer solution. The dye-buffer solution is physically entrapped as a homogeneous dispersion in the polymer matrix. The matrix is applied to the exposed glass core of an optical fiber, which may first be coated with a primer to allow the polyurethane matrix to bond firmly to the tip of the optical fiber. The hydrophilic polymeric matrix is preferably coated with a hydrophobic material to help avoid leaching of the dye from the matrix, and to prevent diffusion of hydronium ions into the sensing matrix. The hydrophobic polymer overcoat may thereafter be cured by heat treatment. The hydrophobic coating may also contain a light reflective material such as TiO.sub.2.
摘要翻译：二氧化碳传感器包括由亲水的，透气的交联聚氨酯形成的CO 2感测基质。聚氨酯基质由与二氧化碳水溶液溶液混合时交联的聚氨酯预聚物混合物形成。染料缓冲溶液在聚合物基质中物理截留为均匀分散体。将基质施加到光纤的暴露的玻璃芯上，其可以首先用底漆涂布，以使聚氨酯基质牢固地结合到光纤的末端。亲水性聚合物基质优选用疏水材料涂覆以帮助避免染料从基质中浸出，并防止水合氢离子扩散到感测基质中。此后，疏水聚合物外涂层可以通过热处理固化。疏水涂层还可以含有诸如TiO 2的光反射材料。

5. 发明申请

US20050085708A1 System and method for preparation of cells for 3D image acquisition 审中-公开
标题翻译：用于3D图像采集的细胞的制备和方法
公开(公告)号：US20050085708A1
公开(公告)日：2005-04-21
申请号：US10968645
申请日：2004-10-19
申请人： Mark Fauver , Alan Nelson , John Rahn , Eric Seibel , Florence Patten , Shawn McGuire
发明人： Mark Fauver , Alan Nelson , John Rahn , Eric Seibel , Florence Patten , Shawn McGuire
IPC分类号： G01N21/17 , A61B10/00 , G01N15/14 , G01N21/21 , G01N21/47 , A61B5/05
CPC分类号： G01N15/1468 , G01N15/147 , G01N15/1475 , G01N21/4795 , G01N2015/1006 , G01N2015/1075 , G01N2201/0813 , G01N2223/612 , G06T11/006 , G06T2211/421
摘要： The present invention provides a method for embedding particles in a solid structure including the steps of extruding a slurry of particles and a polymeric solution into a linear polymer medium having particles embedded into a polymer portion; and curing the polymer portion of the linear polymer medium.
摘要翻译：本发明提供一种嵌入固体结构的颗粒的方法，包括以下步骤：将颗粒浆料和聚合物溶液挤出到具有嵌入聚合物部分中的颗粒的线性聚合物介质中; 并固化线性聚合物介质的聚合物部分。

6. 发明申请

US20060172889A1 Low foaming formulation of gylphosate 审中-公开
标题翻译：草甘膦的低起泡配方
公开(公告)号：US20060172889A1
公开(公告)日：2006-08-03
申请号：US10509400
申请日：2003-03-21
申请人： Clyde Barnes , Alan Baylis , Jeffrey Fowler , Alan Nelson
发明人： Clyde Barnes , Alan Baylis , Jeffrey Fowler , Alan Nelson
IPC分类号： A01N57/18 , A01N25/16
CPC分类号： A01N57/20 , A01N25/30 , A01N2300/00
摘要： A low-foaming herbicidal composition comprises glyphosate and a poly(alkylene oxide)alkanol having the formula R1R2CH—R3—(OR4)n—OH (I) wherein R1 and R2 are methyl or ethyl, R3 is a straight chain alkylene group containing from 5 to 12 carbon atoms, R4 is an alkylene group containing 2 or 3 carbon atoms and n is from 4 to 20. Especially preferred is ethoxylated, propoxylated or mixed alkoxylated/propoxylated iso-tridecyl alcohol wherein the degree of alkoxylation is from 6 to 14, for example iso-tridecyl alcohol having 8 polyethylene oxide units. Preferred compositions additionally contain an alkylglycoside.
摘要翻译：低发泡除草组合物包含草甘膦和具有下式的聚（环氧烷）烷醇：R 1 R 2 CH-R 3 - （其中R 1和R 2均为甲基或乙基，其中R 1，R 2，R 2， SUB 3是含有5至12个碳原子的直链亚烷基，R 4是含有2或3个碳原子的亚烷基，n是4至20.特别优选的是乙氧基化的，丙氧基化的或混合的烷氧基化/丙氧基化的异十三烷醇，其中烷氧基化度为6至14，例如具有8个聚环氧乙烷单元的异十三醇。优选的组合物另外含有烷基糖苷。

7. 发明授权

US5903218A Pool alarm 失效
标题翻译：游泳池报警
公开(公告)号：US5903218A
公开(公告)日：1999-05-11
申请号：US131767
申请日：1998-08-10
申请人： Alan Nelson
发明人： Alan Nelson
IPC分类号： G08B21/08 , G08B23/00
CPC分类号： G08B21/084
摘要： A wave motion detector system for a swimming pool includes a transducer responsive to positive and negative pressure changes in swimming pool water and operative to generate corresponding electrical signals. Comparators are responsive to the electrical signals, and operative to generate a crest signal while the positive pressure exceeds a predetermined positive threshold level, and a trough signal while the negative pressure exceeds a predetermined negative threshold level. A band pass filter prevents electrical signals having a frequency greater than a predetermined upper frequency, and lower than a predetermined lower frequency from passing from the transducer to the comparators. A pulse width discriminator is responsive to the crest signal and the trough signal and is operative to generate a qualified crest signal if the crest signal remains active for a first predetermined time interval, and a qualified trough signal if the trough signal remains active for a second predetermined time interval. A counter circuit, responsive to the qualified crest signal and the qualified trough signal, determines a count value which is equal to the number of times the qualified trough signal and the qualified crest signal occur during a counting time interval. A processing circuit includes alarm condition detection circuitry responsive to the count value, and operative to generate an alarm signal if the count value is greater than or equal to a predetermined alarm count value. Annunciator means, responsive to the alarm signal, is operative to indicate an alarm condition if the alarm signal is generated.
摘要翻译：用于游泳池的波浪运动检测器系统包括响应于游泳池水中的正压力和负压变化的换能器，并且用于产生相应的电信号。比较器响应于电信号，并且在正压力超过预定的正阈值电平时产生峰值信号，并且在负压超过预定的负阈值电平时产生谷信号。带通滤波器防止具有大于预定上限频率的频率并且低于从传感器传递到比较器的预定较低频率的电信号。脉冲宽度鉴别器响应波峰信号和波谷信号，并且如果波峰信号在第一预定时间间隔内保持有效，并且如果波谷信号保持有效的第二预定时间间隔，则可操作以产生合格的波峰信号预定时间间隔。响应于合格的峰值信号和合格的槽信号的计数器电路确定等于合格的槽信号和合格的峰值信号在计数时间间隔期间发生的次数的计数值。处理电路包括响应于计数值的报警条件检测电路，并且如果计数值大于或等于预定的报警计数值则可操作以产生报警信号。指示器意味着响应于报警信号，如果产生报警信号，则可以指示报警状态。

8. 发明授权

US11052265B2 Fluence map optimization for field-in-field radiation therapy 有权
公开(公告)号：US11052265B2
公开(公告)日：2021-07-06
申请号：US16272230
申请日：2019-02-11
申请人： Troy Long , Alan Nelson
发明人： Troy Long , Alan Nelson
IPC分类号： A61N5/10
摘要： Improved radiation therapy with field-in-field multi-leaf collimator, utilizing leaf sequencing Field-in-Field's (FIF) to accurately reproduce the input fluence map or original optimized dose distribution. The number of apertures used is constrained to a user-specified value all the way down to as few as 2 apertures which significantly magnifies the effect of poorly formed apertures. The disclosed invention further includes producing fluence maps with a homogenous dose throughout the treated volume utilizing leaf-sequencing Field-in-Field that reproduces more precise input fluence maps to yield optimized dose distribution.

9. 发明申请

US20110172175A1 PROCESS AND COMPOSITION FOR COATING PROPAGATION MATERIAL 审中-公开
标题翻译：涂料传播材料的工艺和组成
公开(公告)号：US20110172175A1
公开(公告)日：2011-07-14
申请号：US11720439
申请日：2005-11-23
申请人： Victor Shui Chiu Chow , Alan Nelson , Jacqueline Behles
发明人： Victor Shui Chiu Chow , Alan Nelson , Jacqueline Behles
IPC分类号： A01N43/16 , B05D3/06 , B05D3/02 , A01P7/04
CPC分类号： A01N25/00 , A01C1/06 , A01N43/90 , A01N51/00 , C09D4/00 , A01N43/54 , A01N43/36 , A01N2300/00
摘要： The present invention provides a process for coating a plant propagation material, including a seed, comprising: a.) providing a propagation material, such as seed, to be coated; b.) applying to the propagation material a composition comprising at least one reactant having reactive functionality and, optionally, at least one active ingredient; and c.) polymerising, crosslinking, curing or otherwise reacting the reactant having reactive functionality on the surface of the plant propagation material to form a coating thereon which may encompass an a.i., when present. The present invention further provides a method for enhancing the safety, quality and/or viability of a plant propagation material, including a seed, comprising providing a coated material having less dust-off.
摘要翻译：本发明提供了一种包括种子的植物繁殖材料的涂覆方法，包括：a）提供待涂覆的繁殖材料，如种子; b。）向增殖材料施用包含至少一种具有反应性官能团的反应物和任选的至少一种活性成分的组合物; 和c）在植物繁殖材料的表面上聚合，交联，固化或以其它方式使具有反应性官能团的反应物反应以形成其上可以包含a.i.当存在时的涂层。本发明还提供了一种用于增强植物繁殖材料（包括种子）的安全性，质量和/或生存力的方法，其包括提供具有较少粉尘的涂层材料。

10. 发明申请

US20060183220A1 Automated cell sample enrichment preparation method 有权
公开(公告)号：US20060183220A1
公开(公告)日：2006-08-17
申请号：US11353353
申请日：2006-02-14
申请人： Alan Nelson , Florence Patten
发明人： Alan Nelson , Florence Patten
IPC分类号： C12N5/06 , C12M3/00
CPC分类号： C12M47/04 , C12M47/02
摘要： A method for automated cell enrichment preparation where biological cells are injected into a first subchamber and flowed through the first subchamber, through a large pore filter and into a second subchamber so that the large pore filter retains particles large particles in the first subchamber, while the biological cells pass through the first filter into the second subchamber and are retained by a small pore filter. After clearing, the biological cells are stained. A solvent exchange leaves the biological cells in solvent and they are released into a concentration module where a portion of the solvent is removed to form an enriched concentrated cell suspension.

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