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    • 3. 发明授权
    • Organic compounds
    • 有机化合物
    • US06313344B1
    • 2001-11-06
    • US09085283
    • 1998-05-27
    • Stephan TrahHenry SzczepanskiOttmar Franz HüterRoger Graham HallSaleem FarooqAlfons Pascual
    • Stephan TrahHenry SzczepanskiOttmar Franz HüterRoger Graham HallSaleem FarooqAlfons Pascual
    • C07C32700
    • C07D261/20A01N37/38A01N37/50A01N43/80C07C251/60C07C323/12C07D261/08C07F9/4021
    • Compounds of formula (I), wherein either X is CH or N, Y is OR1 and Z is O, or X is N, Y is NHR8 and Z is O, S or S(═O); R1, R2 and R3 are as defined according to the specification; m is 0, 1 or 2; R5 is, for example, halogen, C1-C6alkyl, halo-C1-C6alkyl or C3-C6cycloalkyl; n is 0, 1, 2, 3 or 4; R9 is methyl, fluoromethyl or difluoromethyl; A and R7 are as defined according to the specification; D is O, S, —S(═O) or S(═O)2; G is C1-C6aalkylene; T—R6 is R6, —C(═N—O—A1—R77)—R6; —SiR14(R15)—R6; —C(═O)—R6; —C(R16)═C(R17)—R6, —C≡C—R6 or —D—R6; R6 is C1-C4alkyl or unsubstituted or substituted aryl or heteroaryl; A1 and R77 are as defined above for A and R7; L is U—R18, P(OR)vR11R12, P(S)wR11R12 or N(aryl)R13; v and w are 0 or 1; U—R18 is —C(═O)—C(═O)—R18; —C(OH)—C(OH)—R18; —C(═N—O—A1—R7)—R18; a is 0 or 1; b is 0 or 1; R11, R12 and R13 are, for example, C1-C6alkyl, halo-C1-C6alkyl or C3-C6cycloalkyl; R14 and R15 are each independently of the other C1-C4alkyl; R16 and R17 are each independently of the other hydrogen, C1-C4alkyl or halogen and R18 is R5; and, where applicable, their possible E/Z isomers, mixtures of E/Z isomers and/or tautomers, in each case in free form or in salt form, a method of controlling pests, a process for the preparation of those compounds and their use are described.
    • 式(I)化合物,其中X是CH或N,Y是OR 1,Z是O,或X是N,Y是NHR 8,Z是O,S或S(= O); R 1,R 2和R 3如上定义 根据规范; m为0,1或2; R 5为例如卤素,C 1 -C 6烷基,卤代-C 1 -C 6烷基或C 3 -C 6环烷基; n为0,1,2,3或4; R9是甲基,氟甲基或二氟甲基; A和R7如本说明书所定义; D是O,S,-S(= O)或S(= O)2; G是C1-C6亚烷基; T-R6是R6,-C(= N-O-A1-R77)-R6; -SiR14(R15)-R6; -C(= O)-R6; -C(R 16)= C(R 17)-R 6,-C = C-R6或-D-R6; R6是C1-C4烷基或未取代或取代的芳基或杂芳基; A1和R77如对于A和R7所定义; L是U-R18,P(OR)vR11R12,P(S)wR11R12或N(芳基)R13; v和w为0或1; U-R 18为-C(= O)-C(= O)-R 18; -C(OH)-C(OH)-R 18; -C(= N-O-Al-R 7)-R 18; a为0或1; b为0或1; R 11,R 12和R 13为例如C 1 -C 6烷基,卤代-C 1 -C 6烷基或C 3 -C 6环烷基; R 14和R 15各自独立地为C 1 -C 4烷基; R 16和R 17各自独立地为 另一个氢,C 1 -C 4烷基或卤素,R 18是R 5;并且在适用的情况下,它们可能的E / Z异构体,E / Z异构体和/或互变异构体的混合物,在每种情况下以游离形式或盐形式, 控制害虫,制备这些化合物的方法及其用途。
    • 4. 发明授权
    • Benzophenonehydrazones
    • 二苯甲酮腙
    • US5340837A
    • 1994-08-23
    • US83245
    • 1993-06-25
    • Roger G. HallAlfons PascualOdd Kristiansen
    • Roger G. HallAlfons PascualOdd Kristiansen
    • A01N33/26A01N35/02A01N41/04A01N41/06A01N43/30A01N47/02A01N47/12A01N47/40C07C251/86C07C251/88C07C255/61C07C255/66C07C307/06C07C309/65C07C309/66C07C311/05C07C311/51C07D317/46C07D307/87
    • A01N43/30A01N35/02A01N41/04A01N41/06A01N47/02A01N47/12A01N47/40C07C251/86C07C307/06C07C309/65C07C309/66C07C311/51C07D317/46
    • Compounds of the formula ##STR1## wherein each of o and p, independently of the other, is 0, 1, 2, 3, 4 or 5, the radicals R.sub.1 being the same or different when o is greater than 1 and the radicals R.sub.2 being the same or different when p is greater than 1;each of R.sub.1 and R.sub.2, independently of the other, is C.sub.1 -C.sub.4 alkyl, halo-C.sub.1 -C.sub.4 alkyl, halogen, --NO.sub.2, --OH, C.sub.1 -C.sub.4 alkoxy, halo-C.sub.1 -C.sub.4 alkoxy, C.sub.1 -C.sub.4 alkylthio, halo-C.sub.1 -C.sub.4 alkylthio, --O--S(.dbd.O)--R.sub.6, --O--S(.dbd.O).sub.2 --R.sub.6, phenoxy or --N(R.sub.11)SO.sub.2 R.sub.12 and/or two substituents R.sub.1 and/or two substituents R.sub.2 are, independently of one another, together --Y--Z--Y--;R.sub.3 is hydrogen, C.sub.1 -C.sub.4 alkyl or halo-C.sub.1 -C.sub.4 alkyl;R.sub.4 is hydrogen, C.sub.1 -C.sub.4 alkyl, halo-C.sub.1 -C.sub.4 alkyl, unsubstituted phenyl or naphthyl or mono- or di-substituted phenyl or naphthyl;R.sub.5 is --S--R.sub.7, --S(.dbd.O)--R.sub.7, --S(.dbd.O).sub.2 --R.sub.7, --NO.sub.2, --CN, --C(.dbd.O)--R.sub.8 or --C(.dbd.O)--OR.sub.8 ;R.sub.6 is C.sub.1 -C.sub.8 alkyl, or halo-C.sub.1 -C.sub.8 alkyl or phenyl;X is N or C(R.sub.9);each Y, independently of the other, is O or S; andZ is methylene, eth-1,2-ylene, halomethylene or haloeth-1,2-ylene;and the tautomers and salts thereof can be used as pesticidal compositions and can be prepared in a manner known per se.
    • 式(I)的化合物其中o和p各自独立地为0,1,2,3,4或5,当o大于1时,基团R 1相同或不同,并且 当p大于1时,基团R2相同或不同; R 1和R 2各自独立地为C 1 -C 4烷基,卤代C 1 -C 4烷基,卤素,-NO 2,-OH,C 1 -C 4烷氧基,卤代C 1 -C 4烷氧基,C 1 -C 4烷硫基,卤代C 1 -C 4烷硫基, -OS(= O)-R6,-OS(= O)2 -R6,苯氧基或-N(R11)SO2R12和/或两个取代基R1和/或两个取代基R2彼此独立地是-YZY- ; R3是氢,C1-C4烷基或卤代-C1-C4烷基; R4是氢,C1-C4烷基,卤代C1-C4烷基,未取代的苯基或萘基或单或二取代的苯基或萘基; R5是-S-R7,-S(= O)-R7,-S(= O)2-R7,-NO2,-CN,-C(= O)-R8或-C(= O) R 6是C 1 -C 8烷基或卤代C 1 -C 8烷基或苯基; X为N或C(R9); 每个Y独立于O或S; 并且Z是亚甲基,乙-1,2-亚烯基,卤代亚甲基或卤代乙烯基1,2-亚烯基; 并且其互变异构体和盐可以用作农药组合物,并且可以以本身已知的方式制备。
    • 5. 发明授权
    • Benzophenonehydrazones
    • 二苯甲酮腙
    • US5405871A
    • 1995-04-11
    • US223795
    • 1994-04-06
    • Roger G. HallAlfons PascualOdd Kristiansen
    • Roger G. HallAlfons PascualOdd Kristiansen
    • A01N33/26A01N35/02A01N41/04A01N41/06A01N43/30A01N47/02A01N47/12A01N47/40C07C251/86C07C251/88C07C255/61C07C255/66C07C307/06C07C309/65C07C309/66C07C311/05C07C311/51C07D317/46C07D307/87
    • A01N43/30A01N35/02A01N41/04A01N41/06A01N47/02A01N47/12A01N47/40C07C251/86C07C307/06C07C309/65C07C309/66C07C311/51C07D317/46
    • Compounds of the formula ##STR1## wherein each of o and p, independently of the other, is 0, 1, 2, 3, 4 or 5, the radicals R.sub.1 being the same or different when o is greater than 1 and the radicals R.sub.2 being the same or different when p is greater than 1;each of R.sub.1 and R.sub.2, independently of the other, is C.sub.1 -C.sub.4 alkyl, halo-C.sub.1 -C.sub.4 alkyl, halogen, --NO.sub.2, --OH, C.sub.1 -C.sub.4 alkoxy, halo-C.sub.1 -C.sub.4 alkoxy, C.sub.1 -C.sub.4 alkylthio, halo-C.sub.1 -C.sub.4 alkylthio, --O--S(.dbd.O)--R.sub.6, --O--S(.dbd.O).sub.2 --R.sub.6, phenoxy or --N(R.sub.11)SO.sub.2 R.sub.12 and/or two substituents R.sub.1 and/or two substituents R.sub.2 are, independently of one another, together --Y--Z--Y--;R.sub.3 is hydrogen, C.sub.1 -C.sub.4 alkyl or halo-C.sub.1 -C.sub.4 alkyl;R.sub.4 is hydrogen, C.sub.1 -C.sub.4 alkyl, halo-C.sub.1 -C.sub.4 alkyl, unsubstituted phenyl or naphthyl or mono- or di-substituted phenyl or naphthyl;R.sub.5 is --S--R.sub.7, --S(.dbd.O)--R.sub.7, --S(.dbd.O).sub.2 --R.sub.7, --NO.sub.2, --CN, --C(.dbd.O)--R.sub.8 or --C(.dbd.O)--OR.sub.8 ;R.sub.6 is C.sub.1 -C.sub.8 alkyl, or halo-C.sub.1 -C.sub.8 alkyl or phenyl;X is N or C(R.sub.9);each Y, independently of the other, is O or S; andZ is methylene, eth-1,2-ylene, halomethylene or haloeth-1,2-ylene;and the tautomers and salts thereof can be used as pesticidal compositions and can be prepared in a manner known per se.
    • 式(I)的化合物其中o和p各自独立地为0,1,2,3,4或5,当o大于1时,基团R 1相同或不同,并且 当p大于1时,基团R2相同或不同; R 1和R 2各自独立地为C 1 -C 4烷基,卤代C 1 -C 4烷基,卤素,-NO 2,-OH,C 1 -C 4烷氧基,卤代C 1 -C 4烷氧基,C 1 -C 4烷硫基,卤代C 1 -C 4烷硫基, -OS(= O)-R6,-OS(= O)2 -R6,苯氧基或-N(R11)SO2R12和/或两个取代基R1和/或两个取代基R2彼此独立地是-YZY- ; R3是氢,C1-C4烷基或卤代-C1-C4烷基; R4是氢,C1-C4烷基,卤代C1-C4烷基,未取代的苯基或萘基或单或二取代的苯基或萘基; R5是-S-R7,-S(= O)-R7,-S(= O)2-R7,-NO2,-CN,-C(= O)-R8或-C(= O) R 6是C 1 -C 8烷基或卤代C 1 -C 8烷基或苯基; X为N或C(R9); 每个Y独立于O或S; 并且Z是亚甲基,乙-1,2-亚烯基,卤代亚甲基或卤代乙烯基1,2-亚烯基; 并且其互变异构体和盐可以用作农药组合物,并且可以以本身已知的方式制备。
    • 6. 发明授权
    • Thienylthioureas, -isothioureas and -carbodiimides
    • THIENYLTHIOUREAS,-ISOTHIOUREAS和-CARBODIIMIDES
    • US5130331A
    • 1992-07-14
    • US594883
    • 1990-10-09
    • Alfons Pascual
    • Alfons Pascual
    • A01N43/10A01N47/36A01N47/42C07D333/36
    • C07D333/36A01N43/10
    • The novel substituted 3-thienylthioureas, -isothioureas and -carbodiimides of formula I ##STR1## in which R.sub.1 is C.sub.1 -C.sub.12 alkyl, C.sub.1 -C.sub.4 alkyl substituted by a C.sub.3 -C.sub.6 cycloalkyl radical, C.sub.3 -C.sub.8 cycloalkyl, or C.sub.3 -C.sub.6 cycloalkyl substituted by a C.sub.1 -C.sub.4 alkyl radical; R.sub.2, R.sub.3 and R.sub.4 are each, independently of the others, hydrogen, C.sub.1 -C.sub.6 alkyl, phenyl, or phenyl substituted by from 1 to 3 radicals from the group halogen, C.sub.1 -C.sub.6 alkyl, C.sub.1 -C.sub.4 alkoxy and C.sub.1 -C.sub.6 haloalkyl having from 1 to 9 halogen atoms; Z is a group --NH--CS--NH--, --N .dbd.C(SR.sub.5)--NH-- or --N.dbd.C.dbd.N--; and R.sub.5 is C.sub.1 -C.sub.6 alkyl or C.sub.3 -C.sub.5 alkenyl; with the proviso that at least one of the radicals R.sub.2, R.sub.3 and R.sub.4 is other than hydrogen; and the salts of compounds of formula I in which Z is the group --N.dbd.C(SR.sub.5 )--NH--, have valuable pesticidal properties. Compositions containing those compounds, processes for the preparation thereof and their use as pesticides, especially as insecticides and acaricides in agriculture, are described.
    • 式I的新型取代的3-噻吩硫脲 - 异硫脲和 - 碳二亚胺其中R 1是C 1 -C 12烷基,被C 3 -C 6环烷基取代的C 1 -C 4烷基,被C 3 -C 6环烷基取代的C 3 -C 6环烷基或被 C1-C4烷基; R 2,R 3和R 4各自独立地为氢,C 1 -C 6烷基,苯基或被1至3个基团取代的苯基,所述基团为卤素,C 1 -C 6烷基,C 1 -C 4烷氧基和C 1 -C 6卤代烷基,其具有1至 9个卤素原子; Z是基团-NH-CS-NH-,-N = C(SR5)-NH-或-N = C = N-; R5是C1-C6烷基或C3-C5烯基; 条件是基团R2,R3和R4中的至少一个不是氢; 和其中Z为基团-N = C(SR5)-NH-的式I化合物的盐具有有价值的农药性质。 描述了含有这些化合物的组合物,其制备方法及其作为农药的用途,特别是农业中的杀虫剂和杀螨剂。
    • 7. 发明授权
    • Aminopyridines
    • 氨基吡啶
    • US5077304A
    • 1991-12-31
    • US547649
    • 1990-07-02
    • Alfons Pascual
    • Alfons Pascual
    • C07D213/64A01N47/36A01N47/40A01N47/42C07D213/643C07D213/70C07D213/73C07D213/74C07D213/75
    • C07D213/643A01N47/36A01N47/40A01N47/42C07D213/70C07D213/74C07D213/75
    • Novel 3-amino-2,4-dialkylpyridine derivatives ##STR1## in which R.sup.1 and R.sup.2 are each independently C.sub.1 -C.sub.6 alkyl, R.sup.3 is C.sub.1 -C.sub.12 alkyl, C.sub.3 -C.sub.6 cycloalkyl, C.sub.1 -C.sub.4 alkyl substituted by C.sub.3 -C.sub.6 cycloalkyl, or C.sub.3 -C.sub.6 cycloalkyl substituted by C.sub.1 -C.sub.4 alkyl, R.sup.4 is hydrogen, halogen, C.sub.1 -C.sub.6 alkyl, phenoxy, or phenoxy that is mono- or di-substituted by halogen, C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy, C.sub.1 -C.sub.4 alkylthio, C.sub.1 -C.sub.4 alkylamino, di-C.sub.1 -C.sub.4 alkylamino, C.sub.1 -C.sub.4 alkylcarbonylamino, C.sub.1 -C.sub.4 alkylcarbonyl, benzoyl, nitro, cyano, C.sub.1 -C.sub.4 alkoxycarbonyl, C.sub.1 -C.sub.4 haloalkyl or by C.sub.1 -C.sub.4 haloalkoxy, and Z is a bridge member --NH--CS--NH--, --N.dbd.C(SR.sup.5)--NH-- or --N.dbd.C.dbd.N-- wherein R.sup.5 is C.sub.1 -C.sub.6 alkyl or C.sub.3 -C.sub.5 alkenyl, can be used as pesticides. Preferably, insects and arachnids can be controlled.
    • 新的3-氨基-2,4-二烷基吡啶衍生物其中R 1和R 2各自独立地为C 1 -C 6烷基,R 3为C 1 -C 12烷基,C 3 -C 6环烷基,被C 3 -C 6环烷基取代的C 1 -C 4烷基或C 3 被C 1 -C 4烷基取代的C 6环烷基,R 4是氢,卤素,C 1 -C 6烷基,苯氧基或被卤素,C 1 -C 4烷基,C 1 -C 4烷氧基,C 1 -C 4烷硫基,C 1 -C 4烷基氨基 ,C 1 -C 4烷基氨基,C 1 -C 4烷基羰基氨基,C 1 -C 4烷基羰基,苯甲酰基,硝基,氰基,C 1 -C 4烷氧基羰基,C 1 -C 4卤代烷基或C 1 -C 4卤代烷氧基,Z为桥基-NH-CS-NH-,-N = C(SR5)-NH-或-N = C = N-,其中R5为C1-C6烷基或C3-C5烯基,可用作农药。 优选地,可以控制昆虫和蜘蛛。