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1. 发明授权

US07087637B2 Substituted indoles which are PARP inhibitors 有权
标题翻译：取代的吲哚是PARP抑制剂
公开(公告)号：US07087637B2
公开(公告)日：2006-08-08
申请号：US10275574
申请日：2001-05-09
申请人： Roland Grandel , Wilfried Lubisch , Michael Kock , Thomas Hoger , Reinhold Muller , Sabine Schult , Uta Holzenkamp
发明人： Roland Grandel , Wilfried Lubisch , Michael Kock , Thomas Hoger , Reinhold Muller , Sabine Schult , Uta Holzenkamp
IPC分类号： A61K31/40 , C07D204/42 , C07D209/12
CPC分类号： C07D209/08
摘要： The present invention relates to novel indole derivatives, to their preparation and to their use, as inhibitors of the enzyme poly(ADP-ribose)polymerase or PARP (EC 2.4.2.30), for producing drugs.
摘要翻译：本发明涉及用于生产药物的新型吲哚衍生物，其制备及其用途，作为聚（ADP-核糖）聚合酶或PARP（EC 2.4.2.30）酶的抑制剂。

2. 发明授权

US4410998A Current supply device for electrically heating a molten medium 失效
标题翻译：用于电加热熔融介质的电流供应装置
公开(公告)号：US4410998A
公开(公告)日：1983-10-18
申请号：US265574
申请日：1981-05-20
申请人： Fritz Germann, deceased , Eduard Kuntz , Reinhold Muller , Horst Scholz
发明人： Fritz Germann, deceased , Eduard Kuntz , Reinhold Muller , Horst Scholz
IPC分类号： H05B3/00 , C03B5/027
CPC分类号： H05B3/0023
摘要： A system for generating in-phase alternating current components which are fed into a medium held in a melting trough and flow in the medium between electrodes and counterelectrodes immersed in the medium to effect resistance heating. One embodiment of the system includes a supply voltage source, and a plurality of transformers each having a primary winding and a secondary winding, with the primary windings being connected together in series and to the source, each secondary winding being connected between a respective electrode and counterelectrode to provide a respective alternating current component, and each winding having a number of turns corresponding to the desired relative amplitudes of the current components. A second embodiment of the system includes a supply voltage source, at least one input transformer having a primary winding connected to the source and at least one secondary winding, and a plurality of additional transformers each having a primary winding and a secondary winding, with the primary windings of the additional transformers being connected together in series and in a closed loop, each secondary winding of the input transformer being connected in series with at least one secondary winding of the additional transformers between a respective electrode and counterelectrode to provide a respective alternating current component, and each winding of the additional transformers having a number of turns corresponding to the desired relative amplitudes of the current components.
摘要翻译：一种用于产生同相交流分量的系统，其被馈送到保持在熔化槽中的介质中，并且在介于介质之间的介质中流动并浸没在介质中的反电极以实现电阻加热。该系统的一个实施例包括电源电压源和多个具有初级绕组和次级绕组的变压器，其中初级绕组串联连接在一起并连接到源极，每个次级绕组连接在相应的电极和反电极以提供相应的交流分量，并且每个绕组具有与当前分量的期望相对振幅相对应的匝数。该系统的第二实施例包括电源电压源，至少一个输入变压器，其具有连接到源极和至少一个次级绕组的初级绕组，以及多个额外的变压器，每个具有初级绕组和次级绕组，其中附加变压器的初级绕组串联连接在闭环中，输入变压器的每个次级绕组与相应电极和反电极之间的附加变压器的至少一个次级绕组串联连接，以提供相应的交流电分量，并且附加变压器的每个绕组具有与当前分量的期望相对振幅相对应的匝数。

3. 发明申请

US20080083880A1 Tissue irradiation device with at least one electron source and numerous radiation heads 失效
标题翻译：具有至少一个电子源和许多辐射头的组织照射装置
公开(公告)号：US20080083880A1
公开(公告)日：2008-04-10
申请号：US11767697
申请日：2007-06-25
申请人： Jan Forster , Reinhold Muller , Nils Achterberg
发明人： Jan Forster , Reinhold Muller , Nils Achterberg
IPC分类号： H01J1/50 , H01J3/26
CPC分类号： A61N5/1081 , A61N5/1067 , A61N5/1084 , A61N2005/1089
摘要： A device for irradiating tissue encompassing at least one electron source for generating an electron beam, numerous radiation heads that are firmly and annularly arranged in a supporting frame around an isocenter of the device and emit radiation towards the isocenter, and one beam guidance system to guide the electron beam in the housing towards the radiation heads. The beam guidance system has been built as a polygon, especially as a pentagon arranged like a ring around the isocenter, in which case media for deflecting the electron beam have been placed at every corner point of the polygon.
摘要翻译：用于照射包围至少一个电子源的组织以产生电子束的装置，许多辐射头被牢固且环形地布置在围绕装置的等角点的支撑框架中并朝向等角点发射辐射，以及一个光束引导系统以引导壳体中的电子束朝向辐射头。光束引导系统已经被构建为多边形，特别是作为围绕等角点的环状排列的五边形，在这种情况下，用于偏转电子束的介质已经被放置在多边形的每个角点。

4. 发明授权

US06174194B1 Add-on electrical assembly with light transmission means 失效
标题翻译：带光传输装置的附加电气组件
公开(公告)号：US06174194B1
公开(公告)日：2001-01-16
申请号：US09310805
申请日：1999-05-12
申请人： Matthias Bleicher , Frank Bordron , Martin Buss , Michael Fasold , Thomas Hans Foerner , Michael Follmann , Heinrich Fuchslocher , Gerd Klaiber , Reinhold Muller
发明人： Matthias Bleicher , Frank Bordron , Martin Buss , Michael Fasold , Thomas Hans Foerner , Michael Follmann , Heinrich Fuchslocher , Gerd Klaiber , Reinhold Muller
IPC分类号： H01R1300
CPC分类号： H01R13/717 , H01R13/7172 , H01R13/7175 , H01R24/64
摘要： An add-on electrical assembly is provided for association with an electrical connector for receiving a complementary mating plug to a circuit board. The electrical connector may be a standard modular jack including a connector housing having a front face with a receptacle receiving the plug, a top wall, a rear wall and a bottom face adapted for mounting on the circuit board. A plurality of terminals each include one end extending into the receptacle for making electrical contact with a corresponding terminal on the plug and the other end adapted to contact the circuit board. A separate LED assembly is provided with housing for mounting over the top and rear walls of the connector housing. A light emitting device is mounted on the LED housing and is viewable through a front face thereof adjacent the receptacle. Conductors extend from the light emitting device through the LED housing for connection to the circuit board. At least one snap latch is provided between the LED housing and the connector housing.
摘要翻译：提供了附加电气组件，用于与电连接器相关联，用于将互补的匹配插头接收到电路板。电连接器可以是标准模块插座，其包括连接器壳体，该连接器壳体具有正面，其具有容纳插头的插座，顶壁，后壁和适于安装在电路板上的底面。多个端子各自包括延伸到插座中的一端，用于与插头上的相应端子进行电接触，而另一端适于接触电路板。单独的LED组件设置有用于安装在连接器壳体的顶壁和后壁上的壳体。发光装置安装在LED壳体上，并且可以通过其邻近容器的前表面观察。导体从发光器件延伸通过LED外壳，用于连接到电路板。在LED外壳和连接器外壳之间提供至少一个卡扣。

5. 发明申请

US20080137805A1 Computer tomograph 失效
标题翻译：计算机断层扫描仪
公开(公告)号：US20080137805A1
公开(公告)日：2008-06-12
申请号：US11829222
申请日：2007-07-27
申请人： Jan Forster , Reinhold Muller
发明人： Jan Forster , Reinhold Muller
IPC分类号： A61B6/00
CPC分类号： H01J35/30 , A61B6/032 , A61B6/035 , A61B6/4028 , A61B6/4291 , A61B6/482 , A61B6/50
摘要： A computer tomograph (1) that comprises at least a stationary electron source for generating an electron beam (13), a ring-shaped, stationary X-ray source with a largely ring-shaped target (14) enclosing a measuring field (7), media for coaxially guiding (22) the electron beam (13) in the X-ray source (5) along a circular path to the ring-shaped target (14), as well as media for deflecting (21) the electron beam (13) towards the target (14), in order to generate an X-ray cluster (8) that rotates concentrically around itself for irradiating the measuring field (7) from various directions. Furthermore, the computer tomograph (1) comprises a stationary detector (6) executed as a ring shape and consisting of numerous detector elements from which a computer calculates the measured values to create an image of the examined object in the measuring field (7). The ring-shaped target (14) has numerous discrete focal areas (20) that can be scanned discontinuously by a focal point of the electron beam (13′).
摘要翻译：一种计算机断层摄影机（1），其至少包括用于产生电子束（13）的固定电子源，具有包围测量场（7）的大环形靶（14）的环形固定X射线源，用于同时引导（22）X射线源（5）中的电子束（13）的介质沿着环形目标（14）的圆形路径引导（22），以及用于偏转（21）电子束的介质 13）朝向目标（14），以便产生围绕自身同心旋转的X射线簇（8），以从各个方向照射测量场（7）。此外，计算机断层摄影机（1）包括执行为环形的静止检测器（6），并且由许多检测器元件组成，计算机从计算机计算测量值以在测量区域（7）中创建被检查物体的图像。环形靶（14）具有许多离散的焦点区域（20），其可被电子束（13'）的焦点不连续地扫描。

6. 发明授权

US4289592A Method of separating isotope compounds by selective excitation and reaction in a solid matrix 失效
标题翻译：通过固体基质中选择性激发和反应分离同位素化合物的方法
公开(公告)号：US4289592A
公开(公告)日：1981-09-15
申请号：US895510
申请日：1978-04-11
申请人： Karl Janner , Klaus Gregorius , Reinhold Muller
发明人： Karl Janner , Klaus Gregorius , Reinhold Muller
IPC分类号： B01D59/34 , H01S3/00
CPC分类号： B01D59/34
摘要： Separation of an isotope substance from a vaporous mixture of isotope substances such as UF.sub.6, by selective excitation of low temperature of one isotope compound by electromagnetic radiation to effect chemical reaction of the excited isotope compound with a reaction partner. Separate bodies of the vaporous mixture of isotope compounds and the reaction partner are cooled by adiabatic expansion to a temperature below 100 K. The cooled vapors are mixed in a chamber where the reaction partner is condensed to form solid matter into which isotope compounds are incorporated. The solid matter with or without compacting is subjected to radiation to excite one isotope compound and react it with the reaction product to produce a reaction product which contains predominently the one isotope.
摘要翻译：通过电磁辐射选择性地激发一种同位素化合物的低温，使同位素物质如UF6的汽相混合物分离，以实现激发的同位素化合物与反应配偶体的化学反应。通过绝热膨胀将同位素化合物和反应配对物的蒸汽混合物的分开的物质冷却至低于100K的温度。将冷却的蒸气在反应配对物冷凝的室中混合，形成固体物质，并加入同位素化合物。具有或不具有压实的固体物质经受辐射以激发一种同位素化合物并与反应产物反应以产生主要包含一种同位素的反应产物。

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