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1. 发明授权

US07105508B1 Integrin receptors antagonists 有权
标题翻译：整合素受体拮抗剂
公开(公告)号：US07105508B1
公开(公告)日：2006-09-12
申请号：US10049266
申请日：2000-08-01
申请人： Andreas Kling , Hervé Geneste , Udo Lange , Arnulf Lauterbach , Claudia Isabella Graef , Thomas Subkowski , Uta Holzenkamp , Helmut Mack , Jens Sadowski , Wilfried Hornberger , Volker Laux
发明人： Andreas Kling , Hervé Geneste , Udo Lange , Arnulf Lauterbach , Claudia Isabella Graef , Thomas Subkowski , Uta Holzenkamp , Helmut Mack , Jens Sadowski , Wilfried Hornberger , Volker Laux
IPC分类号： C07D401/12 , A61K31/55
CPC分类号： C07D401/06 , C07D223/20 , C07D243/38 , C07D401/12 , C07D401/14 , C07D403/12 , C07D403/14 , C07D409/12 , C07D409/14 , C07D417/06 , C07D417/12 , C07D417/14 , C07D471/04 , C07D495/04 , C07D495/14
摘要： The invention relates to novel compounds which bind to integrin receptors, and to the preparation thereof and the use thereof as drugs.
摘要翻译：本发明涉及结合整联蛋白受体的新化合物及其制备及其作为药物的用途。

2. 发明申请

US20110240721A1 MICROWAVE-ACTIVATABLE ADHESIVE COMPOSITIONS FOR PRODUCING FOLDING-CARTON BLANKS 审中-公开
标题翻译：用于生产折叠棉布的微波激活胶粘剂组合物
公开(公告)号：US20110240721A1
公开(公告)日：2011-10-06
申请号：US13041755
申请日：2011-03-07
申请人： Dieter Urban , Karl-Heinz Schumacher , Stefan Kirsch , Uta Holzenkamp
发明人： Dieter Urban , Karl-Heinz Schumacher , Stefan Kirsch , Uta Holzenkamp
IPC分类号： B31B1/62 , B65D5/62
CPC分类号： C09J133/08 , B31B50/626
摘要： Described is the use of a microwave-activatable adhesive composition for producing folding-carton blanks for the microwave-activated production of folding cartons. The adhesive composition preferably at less than or equal to 25° C. has an Ig G′ value of greater than or equal to 6 and at greater than or equal to 120° C. has an Ig G′ value of less than or equal to 4, and comprises at least one polymer having a glass transition temperature of greater than 30° C., the folding-carton blanks with adhesive composition applied thereto being blocking-resistant at 25° C. prior to microwave activation.
摘要翻译：描述了使用微波激活的粘合剂组合物来生产用于微波激活生产折叠纸箱的折叠纸箱坯料。粘合剂组合物优选在小于或等于25℃下具有大于或等于6且大于或等于120℃的IgG'值，其IgG'值小于或等于 4，并且包含至少一种具有大于30℃的玻璃化转变温度的聚合物，在微波活化之前，在25℃下具有粘合剂组合物的折叠纸盒坯料被阻挡。

3. 发明申请

US20110239593A1 USE OF AN ACTIVATABLE ADHESIVE COMPOSITION FOR PRODUCING FOLDING-CARTON BLANKS 审中-公开
标题翻译：用于生产折叠棉布的活性粘合剂组合物的使用
公开(公告)号：US20110239593A1
公开(公告)日：2011-10-06
申请号：US13042804
申请日：2011-03-08
申请人： Dieter URBAN , Karl-Heinz Schumacher , Stefan Kirsch , Uta Holzenkamp
发明人： Dieter URBAN , Karl-Heinz Schumacher , Stefan Kirsch , Uta Holzenkamp
IPC分类号： B65B5/02 , B31B1/62 , B65D5/56 , B31B3/60
CPC分类号： B65B51/10 , B31B50/62 , B65B43/265
摘要： Described is the use of an activatable adhesive composition for producing a folding-carton blank which is blocking-resistant at 25° C. with adhesive composition applied thereto. The adhesive composition has at less than or equal to 25° C. an Ig G′ value of greater than or equal to 6 and at greater than or equal to 120° C. has an Ig G′ value of less than or equal to 4, and comprises a copolymer having a glass transition temperature of greater than 30° C. The copolymer is formed from a first monomer and from more than 3% by weight and less than 40% by weight of a second monomer, the first monomer being selected from alkyl (meth)acrylates and vinylaromatics, and the second monomer being selected from ethylenically unsaturated monomers having acid groups and hydroxyalkyl (meth)acrylates.
摘要翻译：描述了使用可活化的粘合剂组合物来生产折叠纸盒坯料，该粘合剂组合物在25℃下具有阻燃性，并且涂覆有粘合剂组合物。粘合剂组合物具有小于或等于25℃，IgG'大于或等于6且大于或等于120℃的Ig G'值小于或等于4 ，并且包含玻璃化转变温度大于30℃的共聚物。共聚物由第一单体和大于3重量％且小于40重量％的第二单体形成，选择第一单体来自（甲基）丙烯酸烷基酯和乙烯基芳族化合物，第二单体选自具有酸基和（甲基）丙烯酸羟烷基酯的烯属不饱和单体。

4. 发明授权

US06696437B1 Heterocyclically substituted benzimidazoles, the production and application thereof 有权
标题翻译：杂环取代的苯并咪唑，的生产和应用
公开(公告)号：US06696437B1
公开(公告)日：2004-02-24
申请号：US09959632
申请日：2002-03-25
申请人： Wilfried Lubisch , Michael Kock , Thomas Hoeger , Roland Grandel , Uta Holzenkamp , Sabine Schult , Reinhold Mueller
发明人： Wilfried Lubisch , Michael Kock , Thomas Hoeger , Roland Grandel , Uta Holzenkamp , Sabine Schult , Reinhold Mueller
IPC分类号： C07D40104
CPC分类号： C07D401/04 , C07D235/18 , C07D403/04
摘要： The present invention relates to novel benzimidazoles, their preparation and their use as inhibitors of the enzyme poly(ADP-ribose) polymerase or PARP (EC 2.4.2.30) for producing drugs.
摘要翻译：本发明涉及新的苯并咪唑，其制备及其作为多聚（ADP-核糖）聚合酶或PARP（EC 2.4.2.30）酶抑制剂用于生产药物的用途。

5. 发明授权

US06387912B1 Utilization of pyrimidine derivatives for preventing and treating cerebral ischaemia 失效
标题翻译：利用嘧啶衍生物预防和治疗脑缺血
公开(公告)号：US06387912B1
公开(公告)日：2002-05-14
申请号：US09889162
申请日：2001-07-11
申请人： Gerd Steiner , Kurt Schellhaas , Wilfried Lubisch , Uta Holzenkamp , Dorothea Starck , Monika Knopp , Laszlo Szabo , Franz Emling , Francisco Javier Garcia-Ladona , Hans-Peter Hofmann , Liliane Unger
发明人： Gerd Steiner , Kurt Schellhaas , Wilfried Lubisch , Uta Holzenkamp , Dorothea Starck , Monika Knopp , Laszlo Szabo , Franz Emling , Francisco Javier Garcia-Ladona , Hans-Peter Hofmann , Liliane Unger
IPC分类号： A61K31513
CPC分类号： A61K31/505
摘要： Use of pyrimidine derivatives of the formula I where the substituents are as defined in the description, and of their physiologically tolerated salts for producing medicaments for the prophylaxis and treatment of cerebral ischemia and strokes.
摘要翻译：使用式I的嘧啶衍生物，其中取代基如说明书中所定义，以及它们用于制备用于预防和治疗脑缺血和中风的药物的生理学耐受盐。

6. 发明申请

US20090045374A1 ELECTRICALLY CONDUCTIVE, MAGNETIC COMPOSITE MATERIAL, PROCESS FOR ITS PRODUCTION, AND ITS USE 审中-公开
标题翻译：电导体，磁性复合材料，其生产工艺及其使用
公开(公告)号：US20090045374A1
公开(公告)日：2009-02-19
申请号：US12192610
申请日：2008-08-15
申请人： Dirk LAWRENZ , Ingolf Hennig , Andrey Karpov , Stefan Kirsch , Hartmut Hibst , Juergen Kaczun , Uta Holzenkamp , Stephen Ems , Harry Thomas Mills , Paul Edwin Gloor
发明人： Dirk LAWRENZ , Ingolf Hennig , Andrey Karpov , Stefan Kirsch , Hartmut Hibst , Juergen Kaczun , Uta Holzenkamp , Stephen Ems , Harry Thomas Mills , Paul Edwin Gloor
IPC分类号： H01F1/00 , C01G49/08
CPC分类号： H05B6/64
摘要： Electrically conductive, magnetic composite material, comprising (A) pulverulent, inorganic, magnetic material which is electrically not or only poorly conductive, and (B) an electrically conductive material, selected from the group consisting of pulverulent and liquid carbon-comprising organic materials and pulverulent carbon allotropes, in a ratio by weight of (A):(B)=from 1:100 to 100:1; a process for its production, and its use, and also ferrimagnetic mixed oxide (A) of the general formula I: M″M′″O4 (I), in which M″ is a first metal component which comprises divalent metal cations; and M′″ is a second metal component which comprises trivalent metal cations; capable of production by reacting, in a quantitative ratio such that the resultant ferromagnetic mixed oxide (A) is electrically neutral, divalent metal cations M″ and trivalent metal cations M′″ in aqueous solution and/or dispersion, comprising at least one electrically conductive material (B) and/or at least one material which differs therefrom and which is a binder (C) which dries physically or else is crosslinkable thermally and/or by actinic radiation.
摘要翻译：导电性磁性复合材料，其包含（A）不具有导电性或导电性差的粉状，无机，磁性材料，和（B）导电材料，其选自由含有粉状和液态碳的有机材料和粉末碳同素异形体，以（A）:( B）的重量比= 1:100至100:1; 其制备方法及其用途，以及通式I的亚铁磁性混合氧化物（A）：<？in-line-formula description =“In-line formula”end =“lead”？> M'M ''O4（I），<？in-line-formula description =“In-line Formulas”end =“tail”？>其中M“是包含二价金属阳离子的第一金属成分; M“是包含三价金属阳离子的第二金属组分; 能够通过使得所得铁磁混合氧化物（A）电中性的数量比使水溶液和/或分散体中的二价金属阳离子M“和三价金属阳离子M”反应而制备，包含至少一种导电材料（B）和/或与其不同的至少一种材料，其是物理上干燥的或者是通过光化辐射可交联的粘合剂（C）。

7. 发明申请

US20080206417A1 Sealable Laminate for Reclosable Packaging 审中-公开
标题翻译：可密封包装的可密封层压板
公开(公告)号：US20080206417A1
公开(公告)日：2008-08-28
申请号：US11995877
申请日：2006-07-21
申请人： Stefan Kirsch , Andree Dragon , Uta Holzenkamp , Cornelis Petrus Beyers
发明人： Stefan Kirsch , Andree Dragon , Uta Holzenkamp , Cornelis Petrus Beyers
IPC分类号： B32B27/06 , B32B27/32 , B32B27/36 , B29C65/52 , B65D77/12 , B65D81/133 , B65D33/16
CPC分类号： C09J7/22 , C09J7/38 , Y10T428/31786 , Y10T428/31801
摘要： A multilayer laminate is composed of a) a backing, b) a pressure-sensitive adhesive layer applied directly to the backing, and c) a wax layer applied directly to the pressure-sensitive adhesive layer.
摘要翻译：多层层压体由a）背衬，b）直接施加到背衬上的压敏粘合剂层组成，c）直接施加到压敏粘合剂层上的蜡层。

8. 发明授权

US07087637B2 Substituted indoles which are PARP inhibitors 有权
标题翻译：取代的吲哚是PARP抑制剂
公开(公告)号：US07087637B2
公开(公告)日：2006-08-08
申请号：US10275574
申请日：2001-05-09
申请人： Roland Grandel , Wilfried Lubisch , Michael Kock , Thomas Hoger , Reinhold Muller , Sabine Schult , Uta Holzenkamp
发明人： Roland Grandel , Wilfried Lubisch , Michael Kock , Thomas Hoger , Reinhold Muller , Sabine Schult , Uta Holzenkamp
IPC分类号： A61K31/40 , C07D204/42 , C07D209/12
CPC分类号： C07D209/08
摘要： The present invention relates to novel indole derivatives, to their preparation and to their use, as inhibitors of the enzyme poly(ADP-ribose)polymerase or PARP (EC 2.4.2.30), for producing drugs.
摘要翻译：本发明涉及用于生产药物的新型吲哚衍生物，其制备及其用途，作为聚（ADP-核糖）聚合酶或PARP（EC 2.4.2.30）酶的抑制剂。

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