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1. 发明申请

US20060064156A1 Atraumatic connections for multi-component stents 失效
标题翻译：多组分支架的无创伤性连接
公开(公告)号：US20060064156A1
公开(公告)日：2006-03-23
申请号：US10946199
申请日：2004-09-21
申请人： Robert Thistle , Kristian DiMatteo
发明人： Robert Thistle , Kristian DiMatteo
IPC分类号： A61F2/06
CPC分类号： A61F2/90 , A61F2220/0016 , A61F2230/0017 , A61F2230/0034 , A61F2230/0054 , A61F2250/0068
摘要： A stent is provided that includes at least two stent segments which mate with one another. At least one of the stent segments includes a hollow member, and at least one of the stent segments includes a solid member. At least one of the solid members is secured to at least one of the hollow members.
摘要翻译：提供一种支架，其包括彼此配合的至少两个支架段。至少一个支架段包括中空构件，并且支架段中的至少一个包括固体构件。固体构件中的至少一个固定到至少一个中空构件。

2. 发明申请

US20050228476A1 Method for inserting a prosthesis 失效
标题翻译：插入假体的方法
公开(公告)号：US20050228476A1
公开(公告)日：2005-10-13
申请号：US11077890
申请日：2005-03-11
申请人： Kristian DiMatteo , Robert Thistle , John Spiridigliozzi
发明人： Kristian DiMatteo , Robert Thistle , John Spiridigliozzi
IPC分类号： A61F2/06
CPC分类号： A61F2/07 , A61F2/88 , A61F2/89 , A61F2/954 , A61F2/958 , A61F2002/065 , A61F2002/075 , A61F2002/9511 , A61F2002/9583 , Y10S623/903
摘要： A graft system for intraluminal delivery in a vessel in need of repair comprising a graft, anchoring means, and a strippable sheath around at least part of the graft. A preferred anchoring means is a balloon-expandable stent. Also included in the invention is a method of using the device to treat a body lumen. The strippable sheath is removable by pulling on a drawstring to remove it which permits expansion of the graft. The positioning of the device may then be adjusted prior to stent dilation. A preferred embodiment of the invention includes a bifurcated graft system for intraluminal delivery in an aortic aneurysm comprising a bifurcated graft having a distal region and two legs, an expandable stent disposed in part of the distal region, and a strippable crocheted sheath around the distal region and one of the two legs. The strippable crocheted sheath is removable by untying it to permit expansion of the graft after initial placement within the aneurysm.
摘要翻译：用于需要修复的血管内腔内输送的移植物系统，包括移植物的至少部分周围的移植物，锚定装置和可剥离护套。优选的锚定装置是球囊可扩张的支架。本发明还包括使用该装置来治疗体腔的方法。可剥离的护套可以通过拉动束带来移除，以移除它，这允许移植物膨胀。然后可以在支架扩张之前调整装置的定位。本发明的优选实施方案包括用于主动脉瘤内腔内递送的分叉移植物系统，其包括具有远侧区域和两条腿的分叉移植物，位于远端区域的一部分中的可扩张支架和围绕远端区域的可剥离钩编护套和两条腿之一。可剥离的钩编护套可以通过拆卸它来移除，以允许在初始放置在动脉瘤内之后扩张移植物。

3. 发明授权

US08048144B2 Prosthesis fixation device and method 失效
标题翻译：假体固定装置及方法
公开(公告)号：US08048144B2
公开(公告)日：2011-11-01
申请号：US10999763
申请日：2004-11-30
申请人： Robert Thistle , Kristian DiMatteo
发明人： Robert Thistle , Kristian DiMatteo
IPC分类号： A61F2/82
CPC分类号： A61B17/11 , A61B17/064 , A61B17/068 , A61B2017/1107 , A61F2/07 , A61F2/848 , A61F2002/075 , A61F2002/8486
摘要： A prosthesis anchor is adapted to convert a previously untreatable anatomy into a more typical and treatable condition. Preferably, the anchor is adapted to be transported endoluminally to a deployment site in a body lumen. The anchor includes a landing section for securing the anchor at a relatively fixed position in the lumen, and a docking section adapted to receive a mating prosthesis the landing section of the anchor may be permanently affixed to the lumen by a variety of mechanical and/or adhesive fixation means.
摘要翻译：假体锚适于将以前不可治疗的解剖结构转换成更典型和可治疗的状况。优选地，该锚适于被运送到体腔内的展开部位。锚固件包括用于将锚定件固定在内腔中的相对固定位置的着陆部分，以及适于接纳配合假体的对接部分，锚固件的着陆部分可以通过各种机械和/或胶粘剂固定装置。

4. 发明授权

US07766959B2 Variable length endovascular graft prosthesis adapted to prevent endoleaks 失效
标题翻译：适用于防止内漏的可变长度血管内移植假体
公开(公告)号：US07766959B2
公开(公告)日：2010-08-03
申请号：US11090522
申请日：2005-03-25
申请人： Kristian DiMatteo , Robert Thistle
发明人： Kristian DiMatteo , Robert Thistle
IPC分类号： A61F2/06
CPC分类号： A61F2/06 , A61F2/064 , A61F2250/006 , A61F2250/0065
摘要： A variable length endovascular prosthesis adapted to prevent endoleaks is provided that includes a substantially tubular first graft member having an interior surface, an exterior surface, and a proximal end, and a substantially tubular second graft member slidably engaged coaxially within the first graft member. The prosthesis further includes a substantially tubular fluid-tight connecting member attached at one end to the first graft member and attached at another end to the second graft member. The connecting member is axially compressible and expandable to facilitate engagement of the second graft member within the first graft member while maintaining a seal between the graft members.
摘要翻译：提供了适于防止内漏的可变长度的血管内假体，其包括具有内表面，外表面和近端的基本上管状的第一移植构件，以及基本上管状的第二移植构件，其同轴地同轴地嵌合在第一移植构件内。假体还包括基本上管状的流体密封连接构件，其一端连接到第一移植构件并且在另一端附接到第二移植构件。连接构件是轴向可压缩和可膨胀的，以便于在第一移植构件内接合第二移植构件，同时保持移植构件之间的密封。

5. 发明授权

US07320703B2 Method for inserting a prosthesis 失效
标题翻译：插入假体的方法
公开(公告)号：US07320703B2
公开(公告)日：2008-01-22
申请号：US11077890
申请日：2005-03-11
申请人： Kristian DiMatteo , Robert Thistle , John Spiridigliozzi
发明人： Kristian DiMatteo , Robert Thistle , John Spiridigliozzi
IPC分类号： A61F2/06
CPC分类号： A61F2/07 , A61F2/88 , A61F2/89 , A61F2/954 , A61F2/958 , A61F2002/065 , A61F2002/075 , A61F2002/9511 , A61F2002/9583 , Y10S623/903
摘要： A graft system for intraluminal delivery in a vessel in need of repair comprising a graft, anchoring means, and a strippable sheath around at least part of the graft. A preferred anchoring means is a balloon-expandable stent. Also included in the invention is a method of using the device to treat a body lumen. The strippable sheath is removable by pulling on a drawstring to remove it which permits expansion of the graft. The positioning of the device may then be adjusted prior to stent dilation. A preferred embodiment of the invention includes a bifurcated graft system for intraluminal delivery in an aortic aneurysm comprising a bifurcated graft having a distal region and two legs, an expandable stent disposed in part of the distal region, and a strippable crocheted sheath around the distal region and one of the two legs. The strippable crocheted sheath is removable by untying it to permit expansion of the graft after initial placement within the aneurysm.
摘要翻译：用于需要修复的血管内腔内输送的移植物系统，包括移植物的至少部分周围的移植物，锚定装置和可剥离护套。优选的锚定装置是球囊可扩张的支架。本发明还包括使用该装置来治疗体腔的方法。可剥离的护套可以通过拉动束带来移除，以移除它，这允许移植物膨胀。然后可以在支架扩张之前调整装置的定位。本发明的优选实施方案包括用于主动脉瘤内腔内递送的分叉移植物系统，其包括具有远侧区域和两条腿的分叉移植物，位于远端区域的一部分中的可扩张支架和围绕远端区域的可剥离钩编护套和两条腿之一。可剥离的钩编护套可以通过拆卸它来移除，以允许在初始放置在动脉瘤内之后扩张移植物。

6. 发明申请

US20100256745A1 VARIABLE LENGTH ENDOVASCULAR GRAFT PROSTHESIS ADAPTED TO PREVENT ENDOLEAKS 失效
标题翻译：可变长度血管内皮细胞肿瘤适应于预防内分泌
公开(公告)号：US20100256745A1
公开(公告)日：2010-10-07
申请号：US12820777
申请日：2010-06-22
申请人： Kristian DiMatteo , Robert Thistle
发明人： Kristian DiMatteo , Robert Thistle
IPC分类号： A61F2/82
CPC分类号： A61F2/06 , A61F2/064 , A61F2250/006 , A61F2250/0065
摘要： A variable length endovascular prosthesis to prevent endoleaks includes a substantially tubular first graft member having an interior surface, an exterior surface, and an open end, and a substantially tubular second graft member engaged coaxially within the first graft member, the second graft member having a proximal end. The prosthesis further includes a substantially tubular fluid-tight connecting member attached at one end to the first graft member and attached at another end to the second graft member, where the connecting member is axially compressible and expandable to facilitate engagement of the proximal end of the second graft member within the first graft member while maintaining a seal between the proximal end of the second graft member and the open end of the first graft member.
摘要翻译：用于防止内漏的可变长度的血管内假体包括具有内表面，外表面和开口端的基本上管状的第一移植件，以及同轴地接合在第一移植件内的基本管状的第二移植件，第二移植件具有近端。所述假体还包括基本上管状的流体密封连接构件，所述连接构件的一端连接到所述第一移植构件，并且在另一端附接到所述第二移植构件，其中所述连接构件是轴向可压缩且可扩张的，以便于接合所述第二移植构件的近端第二移植物件，同时保持第二移植物件的近端和第一移植物件的开口端之间的密封。

7. 发明申请

US20060217796A1 Variable length endovascular graft prosthesis adapted to prevent endoleaks 失效
标题翻译：适用于防止内漏的可变长度血管内移植假体
公开(公告)号：US20060217796A1
公开(公告)日：2006-09-28
申请号：US11090522
申请日：2005-03-25
申请人： Kristian DiMatteo , Robert Thistle
发明人： Kristian DiMatteo , Robert Thistle
IPC分类号： A61F2/06
CPC分类号： A61F2/06 , A61F2/064 , A61F2250/006 , A61F2250/0065
摘要： A variable length endovascular prosthesis adapted to prevent endoleaks is provided that includes a substantially tubular first graft member having an interior surface, an exterior surface, and a proximal end, and a substantially tubular second graft member slidably engaged coaxially within the first graft member. The prosthesis further includes a substantially tubular fluid-tight connecting member attached at one end to the first graft member and attached at another end to the second graft member. The connecting member is axially compressible and expandable to facilitate engagement of the second graft member within the first graft member while maintaining a seal between the graft members.
摘要翻译：提供了适于防止内漏的可变长度的血管内假体，其包括具有内表面，外表面和近端的基本上管状的第一移植构件，以及基本上管状的第二移植构件，其同轴地同轴地嵌合在第一移植构件内。假体还包括基本上管状的流体密封连接构件，其一端连接到第一移植构件并且在另一端附接到第二移植构件。连接构件是轴向可压缩和可膨胀的，以便于在第一移植构件内接合第二移植构件，同时保持移植构件之间的密封。

8. 发明申请

US20060116754A1 Prosthesis fixation device and method 失效
标题翻译：假体固定装置及方法
公开(公告)号：US20060116754A1
公开(公告)日：2006-06-01
申请号：US10999763
申请日：2004-11-30
申请人： Robert Thistle , Kristian DiMatteo
发明人： Robert Thistle , Kristian DiMatteo
IPC分类号： A61F2/06
CPC分类号： A61B17/11 , A61B17/064 , A61B17/068 , A61B2017/1107 , A61F2/07 , A61F2/848 , A61F2002/075 , A61F2002/8486
摘要： A prosthesis anchor is adapted to convert a previously untreatable anatomy into a more typical and treatable condition. Preferably, the anchor is adapted to be transported endoluminally to a deployment site in a body lumen. The anchor includes a landing section for securing the anchor at a relatively fixed position in the lumen, and a docking section adapted to receive a mating prosthesis the landing section of the anchor may be permanently affixed to the lumen by a variety of mechanical and/or adhesive fixation means.
摘要翻译：假体锚适于将先前不可治疗的解剖结构转换成更典型和可治疗的状况。优选地，该锚适于被运送到体腔内的展开部位。锚固件包括用于将锚定件固定在内腔中的相对固定位置的着陆部分，以及适于接纳配合假体的对接部分，锚固件的着陆部分可以通过各种机械和/或胶粘剂固定装置。

9. 发明申请

US20070027531A1 Hypotube endoluminal device and method 失效
标题翻译：低管腔内装置及方法
公开(公告)号：US20070027531A1
公开(公告)日：2007-02-01
申请号：US11541937
申请日：2006-10-02
申请人： Kristian DiMatteo , Robert Thistle
发明人： Kristian DiMatteo , Robert Thistle
IPC分类号： A61F2/06
CPC分类号： A61F2/07 , A61F2/88 , A61F2/90 , A61F2002/067 , A61F2002/075 , A61F2220/005 , A61F2220/0058 , A61F2220/0075
摘要： A self-expanding endoluminal device comprising a tubular filamentary member having a hollow core for receiving a guidewire, the tubular member having a straightened configuration with the guidewire in the hollow core, a shape memory configuration without the guidewire in the hollow core, and an extension, optionally severable, accessible from outside of the body. The hollow core may be adapted to contain and elute or permanently contain a substance, which may be injected through the extension. A delivery system includes the guidewire, and a deployment method includes deployment with a proximal end of the extension accessible from outside of the body.
摘要翻译：一种自膨胀腔内装置，包括具有用于接收导丝的中空芯的管状丝状构件，所述管状构件具有在中空芯中具有导丝的矫直构型，在中空芯中没有导丝的形状记忆构造，以及延伸部，可选地可分开，可从身体外部进入。中空芯可以适于容纳和洗脱或永久地容纳可以通过延伸部注射的物质。递送系统包括导丝，并且展开方法包括展开，其中可从身体外部进入的延伸部的近端。

10. 发明授权

US09555171B2 Methods and devices for collecting separate components of whole blood 有权
标题翻译：用于收集全血分离成分的方法和装置
公开(公告)号：US09555171B2
公开(公告)日：2017-01-31
申请号：US12894271
申请日：2010-09-30
申请人： Mehmet Ziya Sengun , William Parrish , Brooks J. Story , Kristian DiMatteo , Gregory R. Whittaker , Douglas Allen Fifolt
发明人： Mehmet Ziya Sengun , William Parrish , Brooks J. Story , Kristian DiMatteo , Gregory R. Whittaker , Douglas Allen Fifolt
IPC分类号： A01N1/02 , B01D21/26 , B01D21/00 , A61M1/02 , A61M1/36 , B01L3/00
CPC分类号： B04B11/04 , A61K35/16 , A61K35/19 , A61M1/029 , A61M1/3693 , A61M2202/0427 , B01D21/262 , B01D2221/10 , B01L3/5021 , B01L2300/028 , B01L2300/0832 , B01L2400/0409 , B01L2400/0478 , B01L2400/0622 , B04B5/0414 , B04B2011/046
摘要： A method provides for procuring platelet rich plasma (PRP) from a sample of whole blood in a vial. The method includes the steps of: separating the whole blood into layers through centrifugation with an upper layer containing platelet poor plasma (PPP) and a PRP layer below the upper layer containing PRP; adjusting an end point of a first range of motion of an extractor relative to a position of the PRP layer; moving the extractor through the first range of motion through the vial, PPP passing out from the upper layer through the extractor; and after the extractor reaches the end point of the first range of motion, extracting the PRP through the extractor and collecting the PRP.
摘要翻译：一种方法提供从小瓶中的全血样品中获得富血小板血浆（PRP）。该方法包括以下步骤：通过离心将全血分离成含有血小板不足等离子体（PPP）的上层和含有PRP的上层下方的PRP层; 调整提取器相对于PRP层的位置的第一运动范围的终点; 将提取器移动通过小瓶的第一运动范围，PPP从上层通过提取器传出; 并且在提取器到达第一运动范围的终点之后，通过提取器提取PRP并收集PRP。

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