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1. 发明申请

US20080015541A1 Embolectomy Catheters And Methods For Treating Stroke And Other Small Vessel Thromboembolic Disorders 有权
标题翻译：用于治疗中风和其他小血管栓塞性疾病的结肠切除术导管和方法
公开(公告)号：US20080015541A1
公开(公告)日：2008-01-17
申请号：US11773601
申请日：2007-07-05
申请人： Robert Rosenbluth , George Green , Brian Cox , Thomas Sternweiler , Sean Chow , Richard Monetti
发明人： Robert Rosenbluth , George Green , Brian Cox , Thomas Sternweiler , Sean Chow , Richard Monetti
IPC分类号： A61M25/10
CPC分类号： A61B17/22032 , A61B17/135 , A61B17/221 , A61B2017/22034 , A61B2017/22044 , A61B2017/22077 , A61B2017/22084 , A61B2017/22094 , A61B2017/2212 , A61B2017/320716 , A61F2/013 , A61F2002/016 , A61F2002/018 , A61F2230/008 , A61F2230/0091 , A61M2025/0042 , A61M2025/0183
摘要： Embolectomy catheters, rapid exchange microcatheters, systems and methods for removing clots or other obstructive matter (e.g., thrombus, thromboemboli, embolic fragments of atherosclerotic plaque, foreign objects, etc.) from blood vessels. This invention is particularly useable for percutaneous removal of thromboemboli or other obstructive matter from small blood vessels of the brain, during an evolving stroke or period of cerebral ischemia. In some embodiments, the embolectomy catheters of this invention are advanceable with or over a guidewire which has been pre-inserted through or around the clot. Also, in some embodiments, the embolectomy catheters include clot removal devices which are deployable from the catheter after the catheter has been advanced at least partially through the clot. The clot removal device may include a deployable wire nest that is designed to prevent a blood clot from passing therethrough. The delivery catheter may include telescoping inner and outer tubes, with the clot removal device being radially constrained by the outer tube. Retraction of the outer tube removes the constraint on the clot removal device and permits it to expand to its deployed configuration. An infusion guidewire is particularly useful in conjunction with the embolectomy catheter, and permits infusion of medicaments or visualization fluids distal to the clot.
摘要翻译：用于从血管中去除凝块或其他阻塞物（例如，血栓，血栓栓塞，动脉粥样硬化斑块的栓塞碎片，异物等）的系统和方法，快速交换微导管。本发明特别可用于在脑卒中或脑缺血期间经皮去除血栓栓塞或其他来自脑小血管的阻塞物质。在一些实施例中，本发明的止血栓塞导管可以在已经插入穿过凝块或围绕凝块的导丝上或之上前进。此外，在一些实施例中，止血管切除导管包括在导管至少部分地穿过血块前进之后可从导管展开的凝块移除装置。凝块移除装置可以包括被设计成防止血块从其中通过的可展开的线巢。输送导管可以包括伸缩的内管和外管，其中血块去除装置由外管径向约束。外管的收缩消除了对凝块去除装置的约束，并允许其扩展到其部署构型。输注导丝特别适用于结肠切除术导管，并且可以输送远离凝块的药物或可视化液体。

2. 发明授权

US5927282A Controlling urinary incontinence 失效
标题翻译：控制性尿失禁
公开(公告)号：US5927282A
公开(公告)日：1999-07-27
申请号：US116627
申请日：1998-07-16
申请人： Jay Lenker , Robert Rosenbluth , Brian Cox , George R. Greene
发明人： Jay Lenker , Robert Rosenbluth , Brian Cox , George R. Greene
IPC分类号： A61F2/00 , A61F5/44 , A61F5/48 , A61F13/15
CPC分类号： A61F13/471 , A61F13/47209 , A61F2/0009 , A61F2/0054 , A61F5/4401 , A61F5/48 , A61F13/82 , Y10S128/25
摘要： A device for managing urinary incontinence comprises a resilient body that engages the external genitalia and sealingly occludes the urethral meatus. In female embodiments, the body fits between the labia minora and the floor of the vulval vestibule, occluding the meatus. An adhesive on the body provides a sealing engagement with the meatus. In a first female embodiment, the body has a base with an adhesive layer that seats against the vestibule floor. A pair of flexible, lateral flaps engage the labia minora. A layer of super-absorbent material may be situated between the base and the adhesive Layer, and/or a layer of scrim material may be so situated. The body may have a longitudinal ridge with a posterior edge having a finger hole to facilitate installation and removal of the device. In a second female embodiment, the body is substantially tubular, with the adhesive on the exterior surface of the body. In a third female embodiment, the body is an elastomeric bladder, filled with a liquid or gel, that conformingly fits between the labia minora and the vestibule floor so as to occlude the meatus. The exterior surface of the bladder is coated with an adhesive to sealingly occlude the meatus. In male embodiments, the device includes a resilient pad with adhesive on one surface. The pad conforms to and adhesively attaches to the penile glans, with the adhesive sealingly occluding the meatus. Securing tabs may be provided to adhere to the glans or the penile shaft.
摘要翻译：用于管理尿失禁的装置包括与外生殖器接合并密封地封闭尿道口的弹性体。在女性实施例中，身体适合于阴唇小阴唇和外阴前庭的地板之间，阻塞肠道。身体上的粘合剂提供与口腔的密封接合。在第一女性实施例中，身体具有基部，其具有抵靠前庭地板的粘合剂层。一对柔软的外侧襟翼与小阴唇接触。一层超吸收材料可以位于基底和粘合剂层之间，和/或一层稀松布材料可以如此定位。主体可以具有纵向脊，其后边缘具有指孔，以便于装置的安装和拆卸。在第二女性实施例中，身体基本上是管状的，其中粘合剂在身体的外表面上。在第三女性实施例中，身体是充满液体或凝胶的弹性囊，其适配于阴唇小室和前庭地板之间，从而封闭肠道。膀胱的外表面涂有粘合剂以密封地堵塞肠道。在男性实施例中，该装置包括在一个表面上具有粘合剂的弹性垫。垫片符合并粘附到阴茎龟头，粘合剂密封地封闭肠管。可以提供固定突片以粘附到龟头或阴茎轴。

3. 发明申请

US20060184196A1 Microcoil vaso-occlusive device with multi-axis secondary configuration 审中-公开
公开(公告)号：US20060184196A1
公开(公告)日：2006-08-17
申请号：US11398082
申请日：2006-04-05
申请人： Dean Schaefer , Brian Cox , George Greene , David Ferrera , Matthew Fitz , Robert Rosenbluth
发明人： Dean Schaefer , Brian Cox , George Greene , David Ferrera , Matthew Fitz , Robert Rosenbluth
IPC分类号： A61M29/00
CPC分类号： A61B17/12022 , A61B17/12113 , A61B17/12145 , A61B2017/00526 , A61B2017/00867
摘要： A vaso-occlusive device includes a microcoil formed into a minimum energy state secondary configuration comprising a plurality of curved segments, each defining a discrete axis, whereby the device, in its minimum energy state configuration, defines multiple axes. In a preferred embodiment, the secondary configuration-comprises a plurality of interconnected closed loops defining a plurality of discrete axes. In a second embodiment, the secondary configuration defines a wave-form like structure comprising an array of laterally-alternating open loops defining a plurality of separate axes. In a third embodiment, the secondary configuration forms a series of tangential closed loops, wherein the entire structure subtends a first angle of arc, and wherein each adjacent pair of loops defines a second angle of arc. In a fourth embodiment, the secondary configuration forms a logarithmic spiral. In all embodiments, the device, in its secondary configuration, has a dimension that is substantially larger than the largest dimension of the vascular site (i.e., aneurysm) in which it is to be deployed. Thus, confinement of the device within an aneurysm causes it to assume a three-dimensional configuration with a higher energy state than the minimum energy state. Because the minimum energy state configuration of the device is larger (in at least one dimension) than the aneurysm, the deployed device is constrained by its contact with the walls of the aneurysm from returning to its minimum energy state configuration. The engagement of the device with the aneurysm wall minimizes shifting or tumbling due to blood flow. Furthermore, the secondary configuration is not conducive to “coin stacking,” thereby minimizing the compaction experienced.

4. 发明授权

US06461340B1 Urinary incontinence device 失效
标题翻译：尿失禁装置
公开(公告)号：US06461340B1
公开(公告)日：2002-10-08
申请号：US09638255
申请日：2000-08-14
申请人： Jay Lenker , Robert Rosenbluth , Brian Cox , George R. Greene
发明人： Jay Lenker , Robert Rosenbluth , Brian Cox , George R. Greene
IPC分类号： A61F1320
CPC分类号： A61F13/471 , A61F2/0009 , A61F2/0054 , A61F5/4401 , A61F5/48 , A61F13/47209 , A61F13/82 , Y10S128/25
摘要： A device for managing urinary incontinence comprises a resilient body that engages the external genitalia and sealingly occludes the urethral meatus. In female embodiments, the body fits between the labia minora and the floor of the vulval vestibule, occluding the meatus. An adhesive on the body provides a sealing engagement with the meatus. In a first female embodiment, the body has a base with an adhesive layer that seats against the vestibule floor. A pair of flexible, lateral flaps engage the labia minora. A layer of super-absorbent material may be situated between the base and the adhesive layer, and/or a layer of scrim material may be so situated. The body may have a longitudinal ridge with a posterior edge having a finger hole to facilitate installation and removal of the device. In a second female embodiment, the body is substantially tubular, with the adhesive on the exterior surface of the body. In a third female embodiment, the body is an elastomeric bladder, filled with a liquid or gel, that conformingly fits between the labia minora and the vestibule floor so as to occlude the meatus. The exterior surface of the bladder is coated with an adhesive to sealingly occlude the meatus. In male embodiments, the device includes a resilient pad with adhesive on one surface. The pad conforms to and adhesively attaches to the penile glans, with the adhesive sealingly occluding the meatus. Securing tabs may be provided to adhere to the glans or the penile shaft.
摘要翻译：用于管理尿失禁的装置包括与外生殖器接合并密封地封闭尿道口的弹性体。在女性实施例中，身体适合于阴唇小阴唇和外阴前庭的地板之间，阻塞肠道。身体上的粘合剂提供与口腔的密封接合。在第一女性实施例中，身体具有基部，其具有抵靠前庭地板的粘合剂层。一对柔软的外侧襟翼与小阴唇接触。一层超吸收材料可以位于基底和粘合剂层之间，和/或一层稀松布材料可以如此定位。主体可以具有纵向脊，其后边缘具有指孔，以便于装置的安装和拆卸。在第二女性实施例中，身体基本上是管状的，其中粘合剂在身体的外表面上。在第三女性实施例中，身体是充满液体或凝胶的弹性囊，其适配于阴唇小室和前庭地板之间，从而封闭肠道。膀胱的外表面涂有粘合剂以密封地堵塞肠道。在男性实施例中，该装置包括在一个表面上具有粘合剂的弹性垫。垫片符合并粘附到阴茎龟头，粘合剂密封地封闭肠管。可以提供固定突片以粘附到龟头或阴茎轴。

5. 发明授权

US6131575A Urinary incontinence device 失效
公开(公告)号：US6131575A
公开(公告)日：2000-10-17
申请号：US673174
申请日：1996-06-26
申请人： Jay Lenker , Robert Rosenbluth , Brian Cox , George R. Greene
发明人： Jay Lenker , Robert Rosenbluth , Brian Cox , George R. Greene
IPC分类号： A61F2/00 , A61F5/44 , A61F5/48 , A61F13/15
CPC分类号： A61F13/471 , A61F13/47209 , A61F2/0009 , A61F2/0054 , A61F5/4401 , A61F5/48 , A61F13/82 , Y10S128/25
摘要： A device for managing urinary incontinence comprises a resilient body that engages the external genitalia and sealingly occludes the urethral meatus. In female embodiments, the body fits between the labia minora and the floor of the vulval vestibule, occluding the meatus. An adhesive on the body provides a sealing engagement with the meatus. In a first female embodiment, the body has a base with an adhesive layer that seats against the vestibule floor. A pair of flexible, lateral flaps engage the labia minora. A layer of super-absorbent material may be situated between the base and the adhesive layer, and/or a layer of scrim material may be so situated. The body may have a longitudinal ridge with a posterior edge having a finger hole to facilitate installation and removal of the device. In a second female embodiment, the body is substantially tubular, with the adhesive on the exterior surface of the body. In a third female embodiment, the body is an elastomeric bladder, filled with a liquid or gel, that conformingly fits between the labia minora and the vestibule floor so as to occlude the meatus. The exterior surface of the bladder is coated with an adhesive to sealingly occlude the meatus. In male embodiments, the device includes a resilient pad with adhesive on one surface. The pad conforms to and adhesively attaches to the penile glans, with the adhesive sealingly occluding the meatus. Securing tabs may be provided to adhere to the glans or the penile shaft.

6. 发明申请

US20070176333A1 VASCULAR EMBOLIZATION WITH AN EXPANSIBLE IMPLANT 有权
标题翻译：具有可扩展植入物的血管嵌合
公开(公告)号：US20070176333A1
公开(公告)日：2007-08-02
申请号：US11733697
申请日：2007-04-10
申请人： George Greene , Robert Rosenbluth , Brian Cox
发明人： George Greene , Robert Rosenbluth , Brian Cox
IPC分类号： B28B3/00
CPC分类号： A61L31/146 , A61B17/12022 , A61B17/12113 , A61B17/12186 , A61B17/1219 , A61B34/10 , A61B2017/00526 , A61B2017/1205 , A61F2/06 , A61L31/145 , A61L31/18 , A61L2430/36 , B33Y50/00 , B33Y80/00 , Y10S623/901 , Y10S623/903 , Y10T29/49
摘要： A vascular implant formed of a compressible foam material has a compressed configuration from which it is expansible into a configuration substantially conforming to the shape and size of a vascular site to be embolized. Preferably, the implant is formed of a hydrophilic, macroporous foam material, having an initial configuration of a scaled-down model of the vascular site, from which it is compressible into the compressed configuration. The implant is made by scanning the vascular site to create a digitized scan data set; using the scan data set to create a three-dimensional digitized virtual model of the vascular site; using the virtual model to create a scaled-down physical mold of the vascular site; and using the mold to create a vascular implant in the form of a scaled-down model of the vascular site. To embolize a vascular site, the implant is compressed and passed through a microcatheter, the distal end of which has been passed into a vascular site. Upon entering the vascular site, the implant expands in situ substantially to fill the vascular site. A retention element is contained within the microcatheter and has a distal end detachably connected to the implant. A flexible, tubular deployment element is used to pass the implant and the retention element through the microcatheter, and then to separate the implant from the retention element when the implant has been passed out of the microcatheter and into the vascular site.
摘要翻译：由可压缩泡沫材料形成的血管植入物具有压缩构型，其可膨胀到基本上符合要栓塞的血管部位的形状和尺寸的构造。优选地，植入物由亲水的大孔泡沫材料形成，具有血管部位的缩小模型的初始构型，从而可压缩成压缩构型。通过扫描血管部位来创建植入物以产生数字化的扫描数据集; 使用扫描数据集创建血管部位的三维数字化虚拟模型; 使用虚拟模型创建血管部位的缩小物理模具; 并使用模具以血管部位的缩小模型的形式产生血管植入物。为了栓塞血管部位，植入物被压缩并通过微导管，其远端已经进入血管部位。在进入血管部位时，植入物基本上扩张以填充血管部位。保持元件容纳在微导管内并且具有可拆卸地连接到植入物的远端。使用柔性的管状展开元件将植入物和保持元件通过微导管，然后当植入物从微导管通过并进入血管部位时，将植入物与保留元件分离。

7. 发明申请

US20050004660A1 Methods, materials and apparatus for deterring or preventing endoleaks following endovascular graft implantation 审中-公开
标题翻译：用于阻止或防止血管内移植物植入后的内漏的方法，材料和装置
公开(公告)号：US20050004660A1
公开(公告)日：2005-01-06
申请号：US10726135
申请日：2003-12-01
申请人： Robert Rosenbluth , Brian Cox , Jay Lenker
发明人： Robert Rosenbluth , Brian Cox , Jay Lenker
IPC分类号： A61B17/00 , A61B17/12 , A61F2/06 , A61F2/82 , A61L27/00 , A61L29/00
CPC分类号： A61B17/12022 , A61B17/12118 , A61B17/12145 , A61B17/1215 , A61B17/12163 , A61B17/12186 , A61B17/1219 , A61B17/12195 , A61B2017/1205 , A61F2/07 , A61F2002/077
摘要： Methods and apparatus for treating or preventing endoleaks after an endovascular graft (e.g., a stent, tubular graft, stent-graft, coated stent, covered stent, intravascular flow modifier or other endovascular implant that affects, limits or prevents blood flow into a vascular defect such as an aneurysm, arterio-venous fistula, arterio-venous malformation, vessel wall perforation, etc.) has been implanted in the vasculature of a human or veterinary patient. An expansile polymeric material, such as a swellable polymer (e.g., a hydrogel), a flexible or elastomeric polymer foam (e.g. silicone, polyurethane, etc.) or a carrier member (e.g, a coil, filament, wire, etc) that carries a quantity of such expansile polymer is delivered into a perigraft space (i.e., space between the endovascular graft and the surrounding blood vessel wall) such that the polymeric material expands in situ to substantially fill the perigraft space or a portion thereof. The expansile polymeric material is delivered into he perigraft space through a catheter and/or cannula that is placed prior to, during or after the implantation of the endovascular graft. The invention includes an injector apparatus that is useable to deliver the expansile polymeric material through the wall of a previously implanted graft. After delivery into the perigraft space, the expanded polymeric material expands so as to fill all or an intended portion of the perigraft space in a manner that substantially prevents additional blood from leaking or flowing into such perigraft space. One type of blood-absorbing, porous, expansile polymeric material useable in this invention is a super-expansile hydrogel.
摘要翻译：用于治疗或预防血管内移植物（例如，支架，管状移植物，支架移植物，涂层支架，覆膜支架，血管内流动改性剂或影响，限制或防止血液流入血管缺损的其他血管内植入物）中的内漏的方法和装置例如动脉瘤，动静脉瘘，动静脉畸形，血管壁穿孔等）已被植入人或兽医患者的脉管系统中。膨胀聚合物材料，例如可溶胀聚合物（例如，水凝胶），柔性或弹性聚合物泡沫（例如硅树脂，聚氨酯等）或载体（例如，线圈，长丝，电线等），其携带一定数量的这种膨胀聚合物被输送到一个过端口空间（即，血管内移植物和周围的血管壁之间的空间），使得聚合物材料在现场扩张，以基本上填充周围移植物空间或其一部分。通过在血管内移植物植入之前，期间或之后放置的导管和/或插管，将可膨胀的聚合物材料输送到他的围手术处。本发明包括一种可用于通过先前植入的移植物的壁递送可膨胀聚合材料的注射器装置。在递送到周边区域之后，膨胀的聚合物材料膨胀，以便充分填充所述全部或预期部分的过孔面积，以便基本上防止额外的血液泄漏或流入这种周边空间。可用于本发明的一种类型的吸收，多孔，可膨胀的聚合物材料是超膨胀水凝胶。

8. 发明申请

US20060184195A1 Microcoil vaso-occlusive device with multi-axis secondary configuration 有权
公开(公告)号：US20060184195A1
公开(公告)日：2006-08-17
申请号：US11398081
申请日：2006-04-05
申请人： Dean Schaefer , Brain Cox , George Greene , David Ferrera , Matthew Fitz , Robert Rosenbluth
发明人： Dean Schaefer , Brain Cox , George Greene , David Ferrera , Matthew Fitz , Robert Rosenbluth
IPC分类号： A61M29/00
CPC分类号： A61B17/12022 , A61B17/12113 , A61B17/12145 , A61B2017/00867
摘要： A vaso-occlusive device includes a microcoil formed into a minimum energy state secondary configuration comprising a plurality of curved segments, each defining a discrete axis, whereby the device, in its minimum energy state configuration, defines multiple axes. In a preferred embodiment, the secondary configuration comprises a plurality of interconnected closed loops defining a plurality of discrete axes. In a second embodiment, the secondary configuration defines a wave-form like structure comprising an array of laterally-alternating open loops defining a plurality of separate axes. In a third embodiment, the secondary configuration forms a series of tangential closed loops, wherein the entire structure subtends a first angle of arc, and wherein each adjacent pair of loops defines a second angle of arc. In a fourth embodiment, the secondary configuration forms a logarithmic spiral. In all embodiments, the device, in its secondary configuration, has a dimension that is substantially larger than the largest dimension of the vascular site (i.e., aneurysm) in which it is to be deployed. Thus, confinement of the device within an aneurysm causes it to assume a three-dimensional configuration with a higher energy state than the minimum energy state. Because the minimum energy state configuration of the device is larger (in at least one dimension) than the aneurysm, the deployed device is constrained by its contact with the walls of the aneurysm from returning to its minimum energy state configuration. The engagement of the device with the aneurysm wall minimizes shifting or tumbling due to blood flow. Furthermore, the secondary configuration is not conducive to “coin stacking,” thereby minimizing the compaction experienced.

9. 发明申请

US20140303719A1 PERCUTANEOUSLY IMPLANTABLE ARTIFICIAL HEART VALVE SYSTEM AND ASSOCIATED METHODS AND DEVICES 审中-公开
标题翻译： PERCUTANEOUSLY可植入人造心脏瓣膜系统及相关方法和装置
公开(公告)号：US20140303719A1
公开(公告)日：2014-10-09
申请号：US14232238
申请日：2012-06-22
申请人： Brian J. Cox , Robert Rosenbluth , Paul Lubock
发明人： Brian J. Cox , Robert Rosenbluth , Paul Lubock
IPC分类号： A61F2/24
CPC分类号： A61F2/2445 , A61F2/2418 , A61F2/2427 , A61F2/2466 , A61F2220/0008 , A61F2220/0016 , A61F2230/0065 , A61F2250/006
摘要： Expandable prosthetic valve devices for repair or replacement of a native valve in a heart of a patient and associated, systems and methods are disclosed herein. An expandable prosthetic valve device configured in accordance with a particular embodiment of the present technology can include a radially-expandable support having an expandable outer wall and a lumen defined by the outer wall. The device can also include a valve in the lumen and coupled to the support and a self-expanding retainer coupled to the outer wall. The retainer can have a structural braid configured to form a first annular flange on the outer wall of the support, and an occlusive braid configured to reduce blood flow through the retainer.
摘要翻译：用于修复或更换患者心脏中的天然瓣膜的可扩展的假体瓣膜装置以及相关联的系统和方法在此公开。根据本技术的特定实施例配置的可扩张的假体瓣膜装置可以包括具有可扩张的外壁和由外壁限定的内腔的径向可扩张的支撑件。该装置还可以包括在内腔中并且联接到支撑件的阀和联接到外壁的自扩张保持器。保持器可以具有构造成在支撑体的外壁上形成第一环形凸缘的结构编织物，以及闭合编织物，其被构造成减少通过保持器的血流。

10. 发明申请

US20140058436A1 BLOOD FLOW DISRUPTION DEVICES AND METHODS FOR THE TREATMENT OF VASCULAR DEFECTS 审中-公开
标题翻译：血液流量破坏装置及治疗血管缺损的方法
公开(公告)号：US20140058436A1
公开(公告)日：2014-02-27
申请号：US14001818
申请日：2012-02-16
申请人： Robert Rosenbluth , Brian J. Cox
发明人： Robert Rosenbluth , Brian J. Cox
IPC分类号： A61B17/12
CPC分类号： A61B17/12113 , A61B17/12036 , A61B17/12118 , A61B17/12168 , A61B17/12172 , A61B17/12177 , A61B2017/00004 , A61B2017/00477 , A61B2017/00526 , A61B2017/00867 , A61F2/07 , A61F2/90 , A61F2/962 , A61F2002/075 , A61F2002/077 , A61F2210/0014 , A61F2220/0008 , A61F2220/0016 , A61F2220/0033 , A61F2220/005 , A61F2220/0058 , A61F2230/0006 , A61F2230/0065 , A61F2250/0014 , A61F2250/0036 , D04C1/06 , D04C3/48 , D10B2509/06
摘要： A blood flow disruption device for embolizing blood flowing into a vascular defect between a proximal vascular segment and a distal vascular segment, wherein the device includes a porous inner flow disruption element configured to extend through the defect between the proximal vascular segment and the distal vascular segment, whereby a first portion of the blood flowing into the inner flow disruption element from the proximal vascular segment is directed to flow into the defect and a second portion of the blood flowing into the inner flow disruption element is directed to flow into the distal vascular segment. A porous outer flow disruption element coaxially surrounds the inner flow disruption element and is radially expansible from a collapsed state to an expanded state. The outer flow disruption element, in its expanded state, promotes sufficient hemostasis of the first portion of the blood within the defect to embolize the defect.
摘要翻译：一种血流破坏装置，用于栓塞流入近端血管段和远侧血管段之间的血管缺损的血液，其中所述装置包括多孔内部流动破坏元件，其构造成延伸穿过近端血管段和远侧血管段之间的缺陷由此，从近端血管段流入内部流动破坏元件的血液的第一部分被引导流入缺陷，并且流入内部流动破坏元件的血液的第二部分被引导流入远端血管段。多孔外流破坏元件同轴地围绕内部流动破坏元件并且可以从折叠状态径向扩展到膨胀状态。处于其膨胀状态的外部流动破坏元件促进缺陷中血液的第一部分的充分止血以使缺陷栓塞。

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