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1. 发明授权

US07867452B2 Multi-well filtration device 有权
标题翻译：多孔过滤装置
公开(公告)号：US07867452B2
公开(公告)日：2011-01-11
申请号：US11801661
申请日：2007-05-09
申请人： Remo Anton Hochstrasser , Dieter Voegelin , Urs Schwitter , Pirmin Hidber
发明人： Remo Anton Hochstrasser , Dieter Voegelin , Urs Schwitter , Pirmin Hidber
IPC分类号： B01L11/00
CPC分类号： B01L3/50255 , B01L2300/0681 , B01L2300/0829 , B01L2300/0851 , Y10T436/255
摘要： A multi-well filtration device for filtering a suspension comprises a filtration plate with a filtration chamber and a collecting plate with a collecting well. The filtration chamber is connected to the collecting well and a filter element is arranged between the filtration chamber and the collecting well. A separation layer is arranged between the filtration plate and the collecting plate adjacent to the filter element. The use such of a separation layer allows an easy detachment of the filtration plate from the collecting plate. The detached filtration plate can comfortably be transferred into an analysis device, in which the solid phase of the filtration chamber can separately be analyzed through the separation layer, without any replacement of the solid phase.
摘要翻译：用于过滤悬浮液的多孔过滤装置包括具有过滤室的过滤板和具有收集井的收集板。过滤室连接到收集井，过滤室和收集井之间布置过滤元件。在过滤板和与过滤元件相邻的收集板之间布置有分离层。使用这样的分离层允许过滤板从收集板容易地分离。分离的过滤板可以舒适地转移到分析装置中，其中可以通过分离层分离过滤室的固相，而不需要更换固相。

2. 发明申请

US20070297950A1 Equilibration device 审中-公开
标题翻译：平衡装置
公开(公告)号：US20070297950A1
公开(公告)日：2007-12-27
申请号：US11818597
申请日：2007-06-14
申请人： Remo Anton Hochstrasser , Dieter Voegelin , Urs Schwitter , Pirmin Hidber
发明人： Remo Anton Hochstrasser , Dieter Voegelin , Urs Schwitter , Pirmin Hidber
IPC分类号： B01L3/00
CPC分类号： B01L3/50853 , B01L9/06 , B01L2200/141 , B01L2300/044 , B01L2300/0829 , B01L2300/0887 , B01L2300/123
摘要： An equilibration device for equilibrating a comparably economic equilibration of a fluid. A first sealing layer is adjacent to the surface side between the plate and the cover. A second sealing layer is arrangeable adjacent to the cover between the plate and the cover and a tube with an open end, which is inside the well such that the open end of the tube projects above the opening of the well. The use of two sealing layers in the equilibration device allows combining the advantages of a material of the first sealing layer, e.g. high flexibility to seal uneven areas and to compensate the step formed by the tube projecting above the opening of the well, as well as the advantages of the second sealing layer, e.g. inexpensiveness, can come to combined effect when the two sealing layers are arranged appropriately.
摘要翻译：用于平衡流体相对经济平衡的平衡装置。第一密封层邻近板和盖之间的表面侧。第二密封层可布置成邻近板和盖之间的盖，以及具有开口端的管，其在井内，使得管的开口端突出在井的开口上方。在平衡装置中使用两个密封层允许组合第一密封层的材料的优点。高度的柔性以密封不均匀区域并且补偿由突出在井的开口上方的管形成的台阶以及第二密封层的优点，例如，当两个密封层适当布置时，可以实现廉价的组合效果。

3. 发明申请

US20070264163A1 Multi-well filtration device 有权
标题翻译：多孔过滤装置
公开(公告)号：US20070264163A1
公开(公告)日：2007-11-15
申请号：US11801661
申请日：2007-05-09
申请人： Remo Anton Hochstrasser , Dieter Voegelin , Urs Schwitter , Pirmin Hidber
发明人： Remo Anton Hochstrasser , Dieter Voegelin , Urs Schwitter , Pirmin Hidber
IPC分类号： B01L11/00
CPC分类号： B01L3/50255 , B01L2300/0681 , B01L2300/0829 , B01L2300/0851 , Y10T436/255
摘要： A multi-well filtration device for filtering a suspension comprises a filtration plate with a filtration chamber and a collecting plate with a collecting well. The filtration chamber is connected to the collecting well and a filter element is arranged between the filtration chamber and the collecting well. A separation layer is arranged between the filtration plate and the collecting plate adjacent to the filter element. The use such of a separation layer allows an easy detachment of the filtration plate from the collecting plate. The detached filtration plate can comfortably be transferred into an analysis device, in which the solid phase of the filtration chamber can separately be analyzed through the separation layer, without any replacement of the solid phase.
摘要翻译：用于过滤悬浮液的多孔过滤装置包括具有过滤室的过滤板和具有收集井的收集板。过滤室连接到收集井，过滤室和收集井之间布置过滤元件。在过滤板和与过滤元件相邻的收集板之间布置有分离层。使用这样的分离层允许过滤板从收集板容易地分离。分离的过滤板可以舒适地转移到分析装置中，其中可以通过分离层分离过滤室的固相，而不需要更换固相。

4. 发明授权

US07409041B2 Methods of transmission mode X-ray diffraction analysis and apparatuses therefor 有权
$Methods of transmission mode X-ray diffraction analysis and apparatuses therefor$
标题翻译：透射模式X射线衍射分析方法及其设备
公开(公告)号：US07409041B2
公开(公告)日：2008-08-05
申请号：US11416220
申请日：2006-05-02
申请人： Olaf Grassmann , Michael Hennig , Remo Anton Hochstrasser , Urs Schwitter
发明人： Olaf Grassmann , Michael Hennig , Remo Anton Hochstrasser , Urs Schwitter
IPC分类号： G01N23/20
CPC分类号： G01N23/20
摘要： Methods for transmission mode X-ray diffraction analysis of a sample by means of apparatuses comprising an X-ray radiation source that provides X-ray radiation for irradiating the sample and a detector for detecting X-ray radiation transmitted through and diffracted by the sample. The methods include: (a) placing a sample to be analyzed on a substrate, (b) generating X-ray radiation by means of an X-ray radiation source, (c) positioning the substrate and the sample in an initial position, (d) rotating the substrate and the sample with respect to the initial position around a rotation axis over a predetermined rotation angle, (e) tilting the substrate and the sample with respect to the initial position around a tilting axis over a tilting angle, (f) detecting with a detector the X-ray radiation transmitted through and diffracted by the sample during a time interval, and (g) analyzing the X-ray radiation that is detected.
摘要翻译：透射模式X射线衍射分析方法的方法是通过包含X射线辐射源的X射线辐射源，用于照射样品的检测器和用于检测被样品透射并衍射的X射线辐射的检测器的样品。所述方法包括：（a）将待分析的样品放置在基底上，（b）通过X射线辐射源产生X射线辐射，（c）将基底和样品定位在初始位置（（d）使基板和样品相对于围绕旋转轴线的初始位置旋转预定旋转角度，（e）相对于围绕倾斜轴线的倾斜角度的初始位置倾斜基板和样品，（f ）用检测器检测在时间间隔期间由样品透射并衍射的X射线辐射，以及（g）分析检测到的X射线辐射。

5. 发明授权

US07438861B2 Heatable pipette 有权
标题翻译：可加热移液管
公开(公告)号：US07438861B2
公开(公告)日：2008-10-21
申请号：US11804279
申请日：2007-05-16
申请人： Remo Anton Hochstrasser , Dieter Voegelin , Frédéric Ran
发明人： Remo Anton Hochstrasser , Dieter Voegelin , Frédéric Ran
IPC分类号： B01L3/02
CPC分类号： B01L3/021 , B01L2200/147 , B01L2300/1827 , B01L2300/1888 , B01L2400/0487 , G01N35/10 , G01N2035/00425
摘要： A heatable pipette, with a needle has an inner channel defined by an inner wall, arranged to conduct electric current through the inner wall for resistively heating the inner wall. The needle has an outer wall, which is defined between the outer wall and the inner wall and connectable for providing pressure air into the outer channel. By conducting current directly through the inner wall, the inner wall itself operates as resistor. Particularly, if the inner wall is made of an appropriate material, for example of stainless steel, the ohmic resistance of the inner wall is not negligible even if the inner wall is very thin. Therefore, the inner wall can directly be used as resistor for resistance heating of the inner wall even if the needle is manufactured in small dimensions.
摘要翻译：具有针的可加热移液管具有由内壁限定的内部通道，其布置成将电流传导通过内壁以电阻加热内壁。该针具有外壁，该外壁限定在外壁和内壁之间，并且可连接用于将压力空气提供到外部通道中。通过直接通过内壁传导电流，内壁本身作为电阻工作。特别地，如果内壁由适当的材料制成，例如不锈钢，即使内壁非常薄，内壁的欧姆电阻也不可忽略。因此，即使在小尺寸制造针的情况下，内壁也可以直接用作内壁的电阻加热用电阻器。

6. 发明申请

US20070274870A1 Heatable pipette 有权
标题翻译：可加热移液管
公开(公告)号：US20070274870A1
公开(公告)日：2007-11-29
申请号：US11804279
申请日：2007-05-16
申请人： Remo Anton Hochstrasser , Dieter Voegelin , Frederic Ran
发明人： Remo Anton Hochstrasser , Dieter Voegelin , Frederic Ran
IPC分类号： B01L3/02
CPC分类号： B01L3/021 , B01L2200/147 , B01L2300/1827 , B01L2300/1888 , B01L2400/0487 , G01N35/10 , G01N2035/00425
摘要： A heatable pipette, with a needle has an inner channel defined by an inner wall, arranged to conduct electric current through the inner wall for resistively heating the inner wall. The needle has an outer wall, which is defined between the outer wall and the inner wall and connectable for providing pressure air into the outer channel. By conducting current directly through the inner wall, the inner wall itself operates as resistor. Particularly, if the inner wall is made of an appropriate material, for example of stainless steel, the ohmic resistance of the inner wall is not negligible even if the inner wall is very thin. Therefore, the inner wall can directly be used as resistor for resistance heating of the inner wall even if the needle is manufactured in small dimensions.
摘要翻译：具有针的可加热移液管具有由内壁限定的内部通道，其布置成将电流传导通过内壁以电阻加热内壁。该针具有外壁，该外壁限定在外壁和内壁之间，并且可连接用于将压力空气提供到外部通道中。通过直接通过内壁传导电流，内壁本身作为电阻工作。特别地，如果内壁由适当的材料制成，例如不锈钢，即使内壁非常薄，内壁的欧姆电阻也不可忽略。因此，即使在小尺寸制造针的情况下，内壁也可以直接用作内壁的电阻加热用电阻器。

7. 发明授权

US07857575B2 Stacker 有权
标题翻译：堆垛机
公开(公告)号：US07857575B2
公开(公告)日：2010-12-28
申请号：US12079756
申请日：2008-03-27
申请人： Christoph Fattinger , Thomas Zumstein , Remo Anton Hochstrasser , Dieter Voegelin
发明人： Christoph Fattinger , Thomas Zumstein , Remo Anton Hochstrasser , Dieter Voegelin
IPC分类号： B65G59/06 , B65G59/00 , B65H3/30 , G07F11/16
CPC分类号： G01N35/028 , G01N35/0099 , G01N2035/0425
摘要： A stacker (1) for storing a plurality of microplates each having a top surface side and a bottom surface side opposed to the top surface side, comprises a housing and a removal gate (13) for removing a microplate of the plurality of microplates out of the housing. The stacker (1) is arranged to accommodate the plurality of microplates inside the housing such that the top surface side of one microplate of the plurality of microplates abuts on the bottom surface side of an adjacent microplate of the plurality of microplates and such that the housing adjoins to the plurality of microplates. Using such a stacker 1, the plurality of microplates can be arranged and stored in a compact manner wherein the single microplates of the plurality of microplates can still selectively and efficiently be accessed. Further, due to the controlled access to the plurality of microplates being arranged inside the housing of the described stacker 1 via the removal gate 13, icing of the microplates can be minimized when the stacker is cooled for long term storage of samples arranged inside the microplates.
摘要翻译：一种用于存储多个微板的堆叠器（1），每个微板具有与顶表面侧相对的顶表面侧和底表面侧，包括壳体和移除栅极（13），用于将多个微孔板中的微孔板从住房。堆叠器（1）被布置成在壳体内容纳多个微孔板，使得多个微孔板中的一个微孔板的顶表面侧邻接在多个微孔板的相邻微孔板的底表面侧上，邻接多个微孔板。使用这样的堆叠器1，可以以紧凑的方式布置和存储多个微孔板，其中多个微孔板的单个微孔板仍然可以选择性地和有效地被访问。此外，由于经由去除浇口13将所述多个微孔板的控制进入布置在所述堆叠器1的壳体内部，所以当堆积器被冷却以长期储存设置在微孔板内的样品时，微板的结冰可以最小化。

8. 发明申请

US20100086440A1 System and method for robotic storage of microplates 有权
标题翻译：微孔板的机器人储存系统和方法
公开(公告)号：US20100086440A1
公开(公告)日：2010-04-08
申请号：US12587085
申请日：2009-09-30
申请人： Christof Fattinger , Remo Anton Hochstrasser , Dieter Voegelin , Thomas Zumstein
发明人： Christof Fattinger , Remo Anton Hochstrasser , Dieter Voegelin , Thomas Zumstein
IPC分类号： G01N35/10 , B01L3/00
CPC分类号： G01N35/028 , G01N35/0099 , G01N2035/00435 , G01N2035/0425
摘要： In some embodiments of the present disclosure, a robotic storage system for storing microplates carrying a plurality of sample tubes is provided and may comprise a freezer room having a plurality of freezing units and a first robot being capable of removing a microplate from and moving a microplate into a freezing unit. The first robot may be further capable of transferring the microplate to a processing station, where the microplates are stored in the freezing units such that a plurality of microplates are arranged one above the other in a microplate recipient. The robotic storage system may also include at least one processing room and means for thermally separating the processing room from the freezer room. Each processing room may include a processing station having at least one tube transfer module as well as a second robot for moving the microplates between the microplate recipients and the at least one tube transfer module. The first robot may be designed such that it is only capable of removing a microplate recipient from and moving it into a said freezing unit as well as of transferring it from a freezing unit to a processing station or vice versa.
摘要翻译：在本公开的一些实施例中，提供了一种用于存储携带多个样品管的微板的机器人存储系统，并且可以包括具有多个冷冻单元的冷冻室，以及能够从微板移除微孔板并移动微孔板的第一机器人进入冷冻单位。第一机器人可以进一步能够将微板转移到处理站，其中微孔板被存储在冷冻单元中，使得多个微孔板在微孔板接收器中彼此上下排列。机器人存储系统还可以包括至少一个处理室和用于将处理室与冷冻室热分离的装置。每个处理室可以包括具有至少一个管传送模块的处理站以及用于在微板接收器和至少一个管传送模块之间移动微孔板的第二机器人。第一机器人可以设计成使得其仅能够移除微孔板接收器并将其移动到所述冷冻单元中，以及将其从冷冻单元传送到处理站，反之亦然。

9. 发明申请

US20080260511A1 Stacker 有权
标题翻译：堆垛机
公开(公告)号：US20080260511A1
公开(公告)日：2008-10-23
申请号：US12079756
申请日：2008-03-27
申请人： Christoph Fattinger , Thomas Zumstein , Remo Anton Hochstrasser , Dieter Voegelin
发明人： Christoph Fattinger , Thomas Zumstein , Remo Anton Hochstrasser , Dieter Voegelin
IPC分类号： B65G57/00 , F25D15/00
CPC分类号： G01N35/028 , G01N35/0099 , G01N2035/0425
摘要： A stacker (1) for storing a plurality of microplates each having a top surface side and a bottom surface side opposed to the top surface side, comprises a housing and a removal gate (13) for removing a microplate of the plurality of microplates out of the housing. The stacker (1) is arranged to accommodate the plurality of microplates inside the housing such that the top surface side of one microplate of the plurality of microplates abuts on the bottom surface side of an adjacent microplate of the plurality of microplates and such that the housing adjoins to the plurality of microplates. Using such a stacker 1, the plurality of microplates can be arranged and stored in a compact manner wherein the single microplates of the plurality of microplates can still selectively and efficiently be accessed. Further, due to the controlled access to the plurality of microplates being arranged inside the housing of the described stacker 1 via the removal gate 13, icing of the microplates can be minimized when the stacker is cooled for long term storage of samples arranged inside the microplates.
摘要翻译：一种用于存储多个微板的堆叠器（1），每个微板具有与顶表面侧相对的顶表面侧和底表面侧，包括壳体和移除栅极（13），用于将多个微孔板中的微孔板从住房。堆叠器（1）被布置成在壳体内容纳多个微孔板，使得多个微孔板中的一个微孔板的顶表面侧邻接在多个微孔板的相邻微孔板的底表面侧上，邻接多个微孔板。使用这样的堆叠器1，可以以紧凑的方式布置和存储多个微孔板，其中多个微孔板的单个微孔板仍然可以选择性地和有效地被访问。此外，由于经由去除浇口13将所述多个微孔板的控制进入布置在所述堆叠器1的壳体内部，所以当堆积器被冷却以长期储存设置在微孔板内的样品时，微板的结冰可以最小化。

10. 发明授权

US09201084B2 System and method for robotic storage of microplates 有权
标题翻译：微孔板的机器人储存系统和方法
公开(公告)号：US09201084B2
公开(公告)日：2015-12-01
申请号：US12587085
申请日：2009-09-30
申请人： Christof Fattinger , Remo Anton Hochstrasser , Dieter Voegelin , Thomas Zumstein
发明人： Christof Fattinger , Remo Anton Hochstrasser , Dieter Voegelin , Thomas Zumstein
IPC分类号： G01N35/10 , G01N35/02 , G01N35/00 , G01N35/04
CPC分类号： G01N35/028 , G01N35/0099 , G01N2035/00435 , G01N2035/0425
摘要： A robotic microplate storage system includes a freezer room having freezing units and a first robot for moving and removing microplates into and out of the freezing unit. The first robot can also transfer microplates to a processing station, where the microplates are stored in a microplate recipient within the freezing unit. The storage system may also include at least one processing room which is thermally separated from the freezer room. Each processing room may include a processing station having a tube transfer module and a second robot for moving the microplates between the microplate recipients and the tube transfer module. The first robot may be designed such that it is only capable of removing a microplate recipient from and moving it into a freezing unit as well as transferring it from a freezing unit to a processing station or vice versa.
摘要翻译：机器人微板存储系统包括具有冷冻单元的冷冻室和用于移动和移出微孔板进入和离开冷冻单元的第一机器人。第一机器人还可以将微孔板转移到加工站，其中微孔板存储在冷冻单元内的微板接收器中。存储系统还可以包括与冷冻室热分离的至少一个处理室。每个处理室可以包括具有管转移模块和第二机器人的处理站，用于在微板接收器和管传送模块之间移动微板。第一机器人可以设计成使得其仅能够移除微孔板接收器并将其移动到冷冻单元中，并且将其从冷冻单元传送到处理站，反之亦然。

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