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1. 发明授权

US06222544B1 Graphical user interface for radiation therapy treatment apparatus 失效
标题翻译：放射治疗仪的图形用户界面
公开(公告)号：US06222544B1
公开(公告)日：2001-04-24
申请号：US08953780
申请日：1997-10-17
申请人： Randall V. Tarr , Mark G. Wofford
发明人： Randall V. Tarr , Mark G. Wofford
IPC分类号： G06F314
CPC分类号： A61N5/103 , A61N5/1042 , Y10S715/961 , Y10S715/97
摘要： A graphical user interface (1000) for use in a patient treatment system. The graphical user interface (1000) permits graphical display and editing of individual treatment parameters, including machine (2, 4, 6) positions and field shapes. Multiple fields grouped sequentially as an intensity modulated field (IMG) may be viewed as a superimposed graphical composite (1020, 1022, 1024, 1026). In addition, a pictorial representation of the radiation beams (1026) incident on a particular target is provided. A graphic representation of field shape (1030) is provided; the graphics change as treatment progresses. Finally, manipulation of graphics permits editing of treatment information, while allowing immediate feedback as to the result of the change.
摘要翻译：用于患者治疗系统的图形用户界面（1000）。图形用户界面（1000）允许图形显示和编辑各个处理参数，包括机器（2,4,6）位置和场形状。作为强度调制场（IMG）顺序分组的多个区域可以被视为叠加的图形复合物（1020,1022,1024,1026）。此外，提供了入射在特定目标上的辐射束（1026）的图示。提供场形（1030）的图形表示; 随着治疗进展，图形变化。最后，操纵图形允许编辑治疗信息，同时允许立即反馈关于变化的结果。

2. 发明授权

US06249565B1 Fractional monitor unit radiation delivery control using dose rate modulation 失效
标题翻译：使用剂量率调制的分数监视器单元辐射传送控制
公开(公告)号：US06249565B1
公开(公告)日：2001-06-19
申请号：US09100457
申请日：1998-06-18
申请人： Randall V. Tarr
发明人： Randall V. Tarr
IPC分类号： A61N516
CPC分类号： A61N5/1048 , H05G1/44
摘要： Method and system aspects for achieving more accurate radiation delivery during radiation treatment by a radiation-emitting system are described. In a method aspect, and system for achieving same, the method includes providing a table of dose rate values for accumulated dosages in a treatment unit of the radiation emitting system, and controlling a dose rate of radiation emitted from the radiation emitting system through utilization of the table of dose rates. Controlling further includes determining an accumulated dosage at a sampling point, and comparing the accumulated dosage to a total desired dosage. The dose rate is adjusted based on the table of dose rate values and the determined accumulated dosage, with the dose rate ramped down as the accumulated dosage nears the total desired dosage. Accumulated dosages include fractional numbers of monitor units.
摘要翻译：描述了通过辐射发射系统在辐射处理期间实现更准确的辐射传递的方法和系统方面。在方法方面和用于实现其的系统中，该方法包括提供辐射发射系统的处理单元中累积剂量的剂量率值表，以及通过利用辐射发射系统控制从辐射发射系统发射的辐射的剂量率剂量率表。控制进一步包括确定采样点的累积剂量，并将累积剂量与总的所需剂量进行比较。剂量率根据剂量率值和确定的累积剂量表进行调整，剂量率随着累积剂量接近总需要剂量而下降。累计剂量包括监视器单位的分数。

3. 发明授权

US5621779A Apparatus and method for delivering radiation to an object and for displaying delivered radiation 失效
标题翻译：用于将辐射传送到物体并用于显示递送的辐射的装置和方法
公开(公告)号：US5621779A
公开(公告)日：1997-04-15
申请号：US504722
申请日：1995-07-20
申请人： John H. Hughes , Francisco M. Hernandez , Aleksander Ustaszewski , Randall V. Tarr
发明人： John H. Hughes , Francisco M. Hernandez , Aleksander Ustaszewski , Randall V. Tarr
IPC分类号： A61N5/10 , G21F5/04 , G21K1/04 , H05G1/64
CPC分类号： G21K1/04 , A61N5/1048 , G21F5/04 , A61N5/1042
摘要： Radiation output directed toward at least one field of an object, such as a patient, is sensed, for example, during a session of radiation therapy. The accumulated dose delivered to the field is displayed and updated throughout the delivery of radiation. A prescribed dose profile may also be displayed simultaneously so the user can compare the accumulated dose with the prescribed dose profile over the irradiated field. Dose profiles--both prescribed and accumulated--are preferably stored in a memory unit. Profiles for several different fields at several different times may be stored and used to direct and monitor the course of radiation treatment.
摘要翻译：例如，在辐射治疗期间感测针对诸如患者的物体的至少一个场的射线输出。递送到现场的累积剂量在整个辐射传递过程中被显示和更新。也可以同时显示规定的剂量分布，因此用户可以将累积剂量与照射场上的规定剂量分布进行比较。规定和积累的剂量曲线优选地存储在存储单元中。在几个不同时间的几个不同领域的配置文件可以被存储并用于指导和监视辐射治疗的过程。

4. 发明授权

US06240162B1 Precision dosimetry in an intensity modulated radiation treatment system 有权
标题翻译：强度调制放射治疗系统中的精确剂量测定
公开(公告)号：US06240162B1
公开(公告)日：2001-05-29
申请号：US09178388
申请日：1998-10-23
申请人： Francisco M. Hernandez-Guerra , Edward Lewis Calderon , Simon John Forknall , David L. Pond , Hussein Alaifai , Randall V. Tarr
发明人： Francisco M. Hernandez-Guerra , Edward Lewis Calderon , Simon John Forknall , David L. Pond , Hussein Alaifai , Randall V. Tarr
IPC分类号： A61N510
CPC分类号： A61N5/1048
摘要： A system and method for radiation therapy delivery. Known errors are compensated for by applying an offset factor to the dose at the start of the beam cycle. According to one embodiment of the invention, a dosimetry controller is configured to provide the offset connection and sense radiation on (RAD ON) and monitor the dose rate at the beginning of the beam cycle.
摘要翻译：放射治疗递送的系统和方法。已知的误差通过在波束周期开始时对剂量应用偏移因子来补偿。根据本发明的一个实施例，剂量测定控制器被配置为在（RAD ON）上提供偏移连接和感测辐射，并且监测在光束循环开始时的剂量率。

5. 发明授权

US5243983A Non-invasive blood glucose measurement system and method using stimulated Raman spectroscopy 失效
标题翻译：非侵入性血液葡萄糖测量系统和使用刺激拉曼光谱的方法
公开(公告)号：US5243983A
公开(公告)日：1993-09-14
申请号：US627631
申请日：1990-12-14
申请人： Randall V. Tarr , Paul G. Steffes
发明人： Randall V. Tarr , Paul G. Steffes
IPC分类号： A61B3/10 , A61B3/12 , A61B5/00 , A61B5/145 , A61B5/1455 , G01N21/65
CPC分类号： A61B5/1455 , A61B5/14532
摘要： Stimulated Raman spectroscopy is used to non-invasively measure the concentration of an Raman active molecule, preferably D-glucose in the ocular aqueous humor of living being. The apparatus and method make use of two monochromatic laser beams, a pump laser beam and a probe laser beam. The output power of the pump laser beam is amplitude modulated, combined with the probe laser beam and directed into the ocular aqueous humor. The introduction of the laser beams into the ocular aqueous humor induces scattered Raman radiation, which causes a portion of the energy at the pump frequency to shift over to the probe frequency. The pump and probe laser beams are then detected as they exit the ocular aqueous humor. The probe laser beam is filtered, converted into an electrical signal and amplified. It is then compared to the modulation signal to generate an electrical signal representative of the concentration of D-glucose in the ocular aqueous humor.
摘要翻译：受激拉曼光谱法用于非侵入性地测量活体眼水族中的拉曼活性分子，优选D-葡萄糖的浓度。该装置和方法利用两个单色激光束，一个泵激光束和一个探针激光束。将泵激光束的输出功率进行幅度调制，并与探针激光束结合并引导到眼睛的房水中。将激光束引入眼睛房水中会引起散射的拉曼辐射，这导致泵频率下的一部分能量转移到探针频率。然后在泵和探针激光束离开眼睛房水时检测。探头激光束被滤波，转换为电信号并放大。然后将其与调制信号进行比较，以产生代表眼睛房水中D-葡萄糖浓度的电信号。

6. 发明授权

US06577709B2 Fractional monitor unit radiation delivery control using dose rate modulation 有权
标题翻译：使用剂量率调制的分数监视器单元辐射传送控制
公开(公告)号：US06577709B2
公开(公告)日：2003-06-10
申请号：US09850464
申请日：2001-05-07
申请人： Randall V. Tarr
发明人： Randall V. Tarr
IPC分类号： H05G144
CPC分类号： A61N5/1048 , H05G1/44
摘要： Method and system aspects for achieving more accurate radiation delivery during radiation treatment by a radiation-emitting system are described. In a method aspect, and system for achieving same, the method includes providing a table of dose rate values for accumulated dosages in a treatment unit of the radiation emitting system, and controlling a dose rate of radiation emitted from the radiation emitting system through utilization of the table of dose rates. Controlling further includes determining an accumulated dosage at a sampling point, and comparing the accumulated dosage to a total desired dosage. The dose rate is adjusted based on the table of dose rate values and the determined accumulated dosage, with the dose rate ramped down as the accumulated dosage nears the total desired dosage. Accumulated dosages include fractional numbers of monitor units.
摘要翻译：描述了通过辐射发射系统在辐射处理期间实现更准确的辐射传递的方法和系统方面。在方法方面和用于实现其的系统中，该方法包括提供辐射发射系统的处理单元中累积剂量的剂量率值表，以及通过利用辐射发射系统控制从辐射发射系统发射的辐射的剂量率剂量率表。控制进一步包括确定采样点的累积剂量，并将累积剂量与总的所需剂量进行比较。剂量率根据剂量率值和确定的累积剂量表进行调整，剂量率随着累积剂量接近总需要剂量而下降。累计剂量包括监视器单位的分数。

7. 发明授权

US6038284A Precision dosimetry in an intensity modulated radiation treatment system 失效
标题翻译：强度调制放射治疗系统中的精确剂量测定
公开(公告)号：US6038284A
公开(公告)日：2000-03-14
申请号：US7304
申请日：1998-01-15
申请人： Francisco M. Hernandez-Guerra , Edward Lewis Calderon , Simon John Forknall , David L. Pond , Hussein Alrifai , Randall V. Tarr
发明人： Francisco M. Hernandez-Guerra , Edward Lewis Calderon , Simon John Forknall , David L. Pond , Hussein Alrifai , Randall V. Tarr
IPC分类号： A61N5/10
CPC分类号： A61N5/1048
摘要： A system and method for radiation therapy delivery. Known delays are compensated for by applying a compensation factor to the dose at the start of the beam cycle. According to one embodiment of the invention, a dosimetry controller is configured to sense radiation on (RAD ON) and monitor the dose rate at the beginning of the beam cycle. The dosimetry controller then multiplies the dose rate by a compensation factor. Thus, for each beam cycle, the dosimetry controller resolves the magnitude of the lost dose rate data and compensates each segment accordingly.
摘要翻译：放射治疗递送的系统和方法。已知的延迟通过在波束循环开始时向剂量施加补偿因子来补偿。根据本发明的一个实施例，剂量测定控制器被配置为感测（RAD ON）上的辐射并且监测在光束循环开始时的剂量率。然后，剂量测定控制器将剂量率乘以补偿因子。因此，对于每个波束循环，剂量测定控制器解析丢失剂量率数据的大小并相应地补偿每个段。

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