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    • 3. 发明授权
    • Preparation of anhydrous 2-amino-1-methoxypropane
    • 无水2-氨基-1-甲氧基丙烷的制备
    • US5910612A
    • 1999-06-08
    • US82543
    • 1998-05-21
    • Joachim SimonAndreas HenneHeinz Lingk
    • Joachim SimonAndreas HenneHeinz Lingk
    • C07C213/02C07C213/10C07C217/08C07C209/02
    • C07C213/02C07C213/10
    • The process for preparing anhydrous 2-amino-1-methoxypropane proceeds by(a) admixing a 2-amino-1-methoxypropane-containing water-containing reaction mixture, obtainable from the reaction of 1-methoxy-2-propanol with ammonia on a catalyst, with sodium hydroxide solution, forming an aqueous phase containing sodium hydroxide solution and a 2-amino-1-methoxypropane-containing phase,(b) separating off the 2-amino-1-methoxypropane-containing phase from the aqueous phase and(c) distilling the 2-amino-1-methoxypropane-containing phase, an azeotrope of water and 2-amino-1-methoxypropane, which is recycled to step (a) or (b), first being produced and anhydrous 2-amino-1-methoxypropane then being produced.
    • 制备无水2-氨基-1-甲氧基丙烷的方法是:(a)将可从1-甲氧基-2-丙醇反应得到的含2-氨基-1-甲氧基丙烷的含水反应混合物与氨混合, 催化剂,用氢氧化钠溶液,形成含有氢氧化钠溶液和含2-氨基-1-甲氧基丙烷的相的水相,(b)从水相中分离出含2-氨基-1-甲氧基丙烷的相和( c)蒸馏出含有2-氨基-1-甲氧基丙烷的相,再循环至步骤(a)或(b)的水和2-氨基-1-甲氧基丙烷的共沸物,首先制得无水2-氨基-1-甲氧基丙烷, 然后生产1-甲氧基丙烷。