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1. 发明申请

US20110098800A1 AXIALLY ANCHORING COLLAPSIBLE AND RE-EXPANDABLE PROSTHETIC HEART VALVES FOR VARIOUS DISEASE STATES 有权
标题翻译：对各种疾病状态进行轴向锚定和可再膨胀的预防心脏瓣膜
公开(公告)号：US20110098800A1
公开(公告)日：2011-04-28
申请号：US12737254
申请日：2009-07-15
申请人： Peter N. Braido , Julia A. Neuman , Thomas M. Benson
发明人： Peter N. Braido , Julia A. Neuman , Thomas M. Benson
IPC分类号： A61F2/82 , A61F2/24
CPC分类号： A61F2/2412 , A61F2/2418 , A61F2220/0016 , A61F2220/0075 , A61F2230/0054 , A61F2230/008
摘要： A stent (10) for use in a prosthetic heart valve has an annulus section (12) adapted for placement within the leaflets and annulus of the native heart valve. The annulus section has latch members (50) adapted to engage the leaflets of the native heart valve when prosthetic valve is implanted in the native valve. The latch members may hold the leaflets in engagement with the annulus section, and help to retain the prosthetic valve in position. The annulus section may have a non-circular cross-sectional shape.
摘要翻译：用于假体心脏瓣膜的支架（10）具有适于放置在天然心脏瓣膜的瓣叶和环状物中的环形部分（12）。环形部分具有闩锁构件（50），当人工瓣膜植入天然瓣膜时，该构件适于接合天然心脏瓣膜的小叶。闩锁构件可以将小叶保持与环形部分接合，并且有助于将假体瓣保持在适当位置。环形部分可以具有非圆形横截面形状。

2. 发明授权

US09226820B2 Axially anchoring collapsible and re-expandable prosthetic heart valves for various disease states 有权
标题翻译：用于各种疾病状态的轴向锚固可折叠和可再膨胀的假性心脏瓣膜
公开(公告)号：US09226820B2
公开(公告)日：2016-01-05
申请号：US12737254
申请日：2009-07-15
申请人： Peter N. Braido , Julia A. Neuman , Thomas M. Benson
发明人： Peter N. Braido , Julia A. Neuman , Thomas M. Benson
IPC分类号： A61F2/06 , A61F2/24
CPC分类号： A61F2/2412 , A61F2/2418 , A61F2220/0016 , A61F2220/0075 , A61F2230/0054 , A61F2230/008
摘要： A stent (10) for use in a prosthetic heart valve has an annulus section (12) adapted for placement within the ′ leaflets and annulus of the native heart valve. The annulus section has latch members (50) adapted to engage the leaflets of the native heart valve when prosthetic valve is implanted in the native valve. The latch members may hold the leaflets in engagement with the annulus section, and help to retain the prosthetic valve in position. The annulus section may have a non-circular cross-sectional shape.
摘要翻译：用于假体心脏瓣膜的支架（10）具有适于放置在天然心脏瓣膜的小叶和环形空间内的环形部分（12）。环形部分具有闩锁构件（50），当人工瓣膜植入天然瓣膜时，该构件适于接合天然心脏瓣膜的小叶。闩锁构件可以将小叶保持与环形部分接合，并且有助于将假体瓣保持在适当位置。环形部分可以具有非圆形横截面形状。

3. 发明授权

US08808366B2 Stent features for collapsible prosthetic heart valves 有权
标题翻译：支架功能可折叠假体心脏瓣膜
公开(公告)号：US08808366B2
公开(公告)日：2014-08-19
申请号：US13203627
申请日：2010-02-25
申请人： Peter N. Braido , Yousef F. Alkhatib , Thomas M. Benson , Aaron J. Chalekian , Ott Khouengboua , Julia A. Neuman
发明人： Peter N. Braido , Yousef F. Alkhatib , Thomas M. Benson , Aaron J. Chalekian , Ott Khouengboua , Julia A. Neuman
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/915 , A61F2002/91575 , A61F2220/0075 , A61F2230/0054 , A61F2230/0067 , A61F2230/008
摘要： A prosthetic heart valve includes a stent having an expanded condition and a collapsed condition. The stent includes a plurality of distal cells, a plurality of proximal cells, a plurality of support struts coupling the proximal cells to the distal cells, and at least one support post connected to a plurality of proximal cells. The proximal cells are longitudinally spaced apart from the distal cells. Various strut configurations and connections of the struts to the proximal cells and of the proximal cells to the support post improve stent flexibility and reduce stress in the valve leaflets.
摘要翻译：假体心脏瓣膜包括具有扩张状态和折叠状态的支架。支架包括多个远端细胞，多个近端细胞，将近端细胞耦合到远端细胞的多个支撑支柱以及连接到多个近端细胞的至少一个支撑柱。近端细胞与远端细胞纵向间隔开。支柱结构和连接到近端细胞和近端细胞到支撑柱的各种支柱构型和连接可改善支架的灵活性并减少瓣膜小叶中的压力。

4. 发明申请

US20120078347A1 STENT FEATURES FOR COLLAPSIBLE PROSTHETIC HEART VALVES 有权
标题翻译：可靠的前置心脏瓣膜的特点
公开(公告)号：US20120078347A1
公开(公告)日：2012-03-29
申请号：US13203627
申请日：2010-02-25
申请人： Peter N. Braido , Yousef F. Alkhatib , Thomas M. Benson , Aaron J. Chalekian , Ott Khouengboua , Julia A. Neuman
发明人： Peter N. Braido , Yousef F. Alkhatib , Thomas M. Benson , Aaron J. Chalekian , Ott Khouengboua , Julia A. Neuman
IPC分类号： A61F2/82 , A61F2/24
CPC分类号： A61F2/2418 , A61F2/915 , A61F2002/91575 , A61F2220/0075 , A61F2230/0054 , A61F2230/0067 , A61F2230/008
摘要： A prosthetic heart valve includes a stent having an expanded condition and a collapsed condition. The stent includes a plurality of distal cells, a plurality of proximal cells, a plurality of support struts coupling the proximal cells to the distal cells, and at least one support post connected to a plurality of proximal cells. The proximal cells are longitudinally spaced apart from the distal cells. Various strut configurations and connections of the struts to the proximal cells and of the proximal cells to the support post improve stent flexibility and reduce stress in the valve leaflets.
摘要翻译：假体心脏瓣膜包括具有扩张状态和折叠状态的支架。支架包括多个远端细胞，多个近端细胞，将近端细胞耦合到远端细胞的多个支撑支柱以及连接到多个近端细胞的至少一个支撑柱。近端细胞与远端细胞纵向间隔开。支柱结构和连接到近端细胞和近端细胞到支撑柱的各种支柱构型和连接可改善支架的灵活性并减少瓣膜小叶中的压力。

5. 发明授权

US09532887B2 Multi-layer stent 有权
标题翻译：多层支架
公开(公告)号：US09532887B2
公开(公告)日：2017-01-03
申请号：US14124092
申请日：2012-06-12
申请人： Thomas M. Benson , Ott Khouengboua , Peter Nicholas Braido
发明人： Thomas M. Benson , Ott Khouengboua , Peter Nicholas Braido
IPC分类号： A61F2/24 , A61F2/82
CPC分类号： A61F2/2418 , A61F2/2436 , A61F2/82 , A61F2/90 , A61F2210/0076 , A61F2220/0058 , A61F2230/005 , A61F2230/0054 , A61F2230/0067 , A61F2230/0069 , A61F2230/008 , A61F2250/0039
摘要： A collapsible prosthetic heart valve includes a stent and a valve assembly. The stent includes an annulus section and at least one foldable section. The stent is movable between an unfolded condition in which the foldable section is longitudinally spaced from the annulus section, and a folded condition in which the foldable section is at least partially positioned radially adjacent the annulus section. The valve assembly is positioned within the annulus section of the stent in the folded condition of the stent.
摘要翻译：可折叠假体心脏瓣膜包括支架和阀组件。支架包括环形部分和至少一个可折叠部分。支架可在可折叠部分与环形部分纵向间隔开的展开状态和折叠状态之间移动，其中折叠部分至少部分地位于环形部分的径向附近。瓣膜组件在支架的折叠状态下定位在支架的环形部分内。

6. 发明申请

US20140243965A1 MULTI-LAYER STENT 有权
标题翻译：多层架构
公开(公告)号：US20140243965A1
公开(公告)日：2014-08-28
申请号：US14124092
申请日：2012-06-12
申请人： Thomas M. Benson , Ott Khouengboua , Peter Nicholas Braido
发明人： Thomas M. Benson , Ott Khouengboua , Peter Nicholas Braido
IPC分类号： A61F2/82
CPC分类号： A61F2/2418 , A61F2/2436 , A61F2/82 , A61F2/90 , A61F2210/0076 , A61F2220/0058 , A61F2230/005 , A61F2230/0054 , A61F2230/0067 , A61F2230/0069 , A61F2230/008 , A61F2250/0039
摘要： A collapsible prosthetic heart valve includes a stent and a valve assembly. The stent includes an annulus section and at least one foldable section. The stent is movable between an unfolded condition in which the foldable section is longitudinally spaced from the annulus section, and a folded condition in which the foldable section is at least partially positioned radially adjacent the annulus section. The valve assembly is positioned within the annulus section of the stent in the folded condition of the stent.
摘要翻译：可折叠假体心脏瓣膜包括支架和阀组件。所述支架包括环形部分和至少一个可折叠部分。支架可在可折叠部分与环形部分纵向间隔开的展开状态和折叠状态之间移动，其中折叠部分至少部分地位于环形部分的径向附近。瓣膜组件在支架的折叠状态下定位在支架的环形部分内。

7. 外观设计

USD458679S1 Handle 失效
公开(公告)号：USD458679S1
公开(公告)日：2002-06-11
申请号：US29135732
申请日：2001-01-18
申请人： Paul J. Thompson , Thomas M. Benson
设计人： Paul J. Thompson , Thomas M. Benson

8. 发明授权

US08932343B2 Blunt ended stent for prosthetic heart valve 有权
标题翻译：用于假体心脏瓣膜的钝器支架
公开(公告)号：US08932343B2
公开(公告)日：2015-01-13
申请号：US13215893
申请日：2011-08-23
申请人： Yousef F. Alkhatib , Peter Nicholas Braido , Thomas M. Benson
发明人： Yousef F. Alkhatib , Peter Nicholas Braido , Thomas M. Benson
IPC分类号： A61F2/24 , A61F2/95
CPC分类号： A61F2/2418 , A61F2/2436 , A61F2002/9517 , A61F2002/9534 , A61F2220/0075 , A61F2230/0013 , A61F2250/0039
摘要： A collapsible prosthetic heart valve includes a stent and a valve assembly. The stent has a proximal end and a distal end and includes a plurality of struts. The struts have free ends configured to inhibit tissue penetration. The valve assembly, including a plurality of leaflets, is disposed within the stent.
摘要翻译：可折叠假体心脏瓣膜包括支架和阀组件。支架具有近端和远端，并且包括多个支柱。支柱具有构造成抑制组织穿透的自由端。包括多个小叶的阀组件设置在支架内。

9. 发明申请

US20120197390A1 BLUNT ENDED STENT FOR PROSTHETIC HEART VALVE 有权
标题翻译：用于前置心脏瓣膜的BLUNT ENDED STENT
公开(公告)号：US20120197390A1
公开(公告)日：2012-08-02
申请号：US13215893
申请日：2011-08-23
申请人： Yousef F. Alkhatib , Peter Nicholas Braido , Thomas M. Benson
发明人： Yousef F. Alkhatib , Peter Nicholas Braido , Thomas M. Benson
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/2436 , A61F2002/9517 , A61F2002/9534 , A61F2220/0075 , A61F2230/0013 , A61F2250/0039
摘要： A collapsible prosthetic heart valve includes a stent and a valve assembly. The stent has a proximal end and a distal end and includes a plurality of struts. The struts have free ends configured to inhibit tissue penetration. The valve assembly, including a plurality of leaflets, is disposed within the stent.
摘要翻译：可折叠假体心脏瓣膜包括支架和阀组件。支架具有近端和远端，并且包括多个支柱。支柱具有构造成抑制组织穿透的自由端。包括多个小叶的阀组件设置在支架内。

10. 发明授权

US06749627B2 Grip for stent delivery system 有权
标题翻译：夹持支架输送系统
公开(公告)号：US06749627B2
公开(公告)日：2004-06-15
申请号：US09765721
申请日：2001-01-18
申请人： Paul J. Thompson , Thomas M. Benson
发明人： Paul J. Thompson , Thomas M. Benson
IPC分类号： A61F206
CPC分类号： A61F2/95 , A61B17/2909 , A61F2002/9517 , A61M2025/09116 , A61M2025/09125
摘要： A stent delivery system includes inner and outer tubular members with the outer tubular member sized to pass through the body lumen to the deployment site and with the inner tubular member sized to be received within the outer tubular member. The inner and outer tubular members are axially slideable relative to one another between a transport position and a deploy position. The inner tubular member has a stent attachment location at its distal end. The stent attachment location is covered by the outer tubular member when the inner and outer tubular members are in the transport position. The stent attachment location is exposed when the inner and outer tubular members are in the deploy position. A first handle is provided rotatably connected to a proximal end of the outer tubular member for the first handle to transmit to the outer tubular member axial forces applied to the handle by an operator and to rotate freely about the axis relative to the outer tubular member.
摘要翻译：支架输送系统包括内部和外部管状构件，外部管状构件的尺寸设计成穿过体腔到达展开位置，并且内部管状构件的尺寸设置成容纳在外部管状构件内。内部和外部管状构件在运输位置和展开位置之间可相对于彼此轴向滑动。内部管状构件在其远端具有支架附接位置。当内部和外部管状构件处于运输位置时，支架附接位置被外部管状构件覆盖。当内部和外部管状构件处于展开位置时，支架附接位置被暴露。第一手柄设置成可旋转地连接到外部管状构件的近端，用于第一手柄，以便通过操作者向外部管状构件传递施加到手柄的轴向力，并相对于外部管状构件绕该轴线自由旋转。

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