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1. 发明授权

US07797029B2 Auditory midbrain implant 有权
标题翻译：听觉中脑植入
公开(公告)号：US07797029B2
公开(公告)日：2010-09-14
申请号：US10493675
申请日：2002-10-25
申请人： Peter Gibson , Thomas Lenarz , Minoo Lenarz , Miro Mackiewicz , John Parker , James Finlay Patrick
发明人： Peter Gibson , Thomas Lenarz , Minoo Lenarz , Miro Mackiewicz , John Parker , James Finlay Patrick
IPC分类号： A61B5/04 , A61N1/18 , A61N1/05
CPC分类号： A61N1/0529 , A61F11/04 , A61N1/0541 , A61N1/36036
摘要： An electrode array that is implantable within the inferior colliculus of the midbrain and/or other appropriate regions of the brain of an implantee and adapted to provide electrical stimulation thereto. The electrode array an elongate member having a plurality of electrodes mounted thereon in a longitudinal array. A delivery cannula for delivering the electrode array comprised of two half-pipes is also described.
摘要翻译：可植入在植入物的脑的中脑和/或其他适当区域的下丘中并适于对其施加电刺激的电极阵列。电极阵列具有纵向阵列中安装有多个电极的细长构件。还描述了用于输送由两个半管构成的电极阵列的输送插管。

2. 发明申请

US20050004627A1 Auditory midbrain implant 有权
标题翻译：听觉中脑植入
公开(公告)号：US20050004627A1
公开(公告)日：2005-01-06
申请号：US10493675
申请日：2002-10-25
申请人： Peter Gibson , Thomas Lenarz , Minoo Lenarz , Miro Mackiewicz , John Parker , James Patrick
发明人： Peter Gibson , Thomas Lenarz , Minoo Lenarz , Miro Mackiewicz , John Parker , James Patrick
IPC分类号： A61F11/04 , A61N1/05
CPC分类号： A61N1/0529 , A61F11/04 , A61N1/0541 , A61N1/36036
摘要： An electrode array (10) that is implantable within the inferior colliculus of the midbrain and/or other appropriate regions of the brain of an implantee and adapted to provide electrical stimulation thereto. The electrode array (10) an elongate member (11) having a plurality of electrodes (12) mounted thereon in a longitudinal array. A delivery cannula (30) for delivering the electrode array (10) comprised of two half-pipes (31) is also described.
摘要翻译：电极阵列（10），其可植入在植入物的脑的中脑和/或其它适当区域的下丘丘内，并适于对其施加电刺激。电极阵列（10）具有以纵向阵列安装在其上的多个电极（12）的细长构件（11）。还描述了用于输送由两个半管（31）组成的电极阵列（10）的输送插管（30）。

3. 发明授权

US07822478B2 Compressed neural coding 有权
标题翻译：压缩神经编码
公开(公告)号：US07822478B2
公开(公告)日：2010-10-26
申请号：US11094769
申请日：2005-03-31
申请人： Matthijs Killian , Bas van Dijk , Andreas Buechner , Joerg Pesch , Marc Majoral , John Parker , James Finlay Patrick , Ernst Von Wallenberg
发明人： Matthijs Killian , Bas van Dijk , Andreas Buechner , Joerg Pesch , Marc Majoral , John Parker , James Finlay Patrick , Ernst Von Wallenberg
IPC分类号： A61N1/36
CPC分类号： A61N1/36036 , A61N1/0541 , H04R2225/43
摘要： An embodiment of the present invention takes masking effects into consideration when determining stimulations signals for neural stimulation. These masking effects may be modeled using user-specific models determined by taking measurements for an implant system of an implant recipient. Or, the model may correspond to a group of individuals sharing a common characteristic or the population as a whole. These models may be, for example, psycho-physical or electrophysiological models.
摘要翻译：当确定用于神经刺激的刺激信号时，本发明的实施例考虑到掩蔽效应。可以使用通过对植入物接收者的植入物系统进行测量而确定的用户特定模型来建模这些掩蔽效应。或者，该模型可能对应于一组共享特征或整体人口的个体。这些模型可能是例如心理物理或电生理模型。

4. 发明申请

US20060020318A1 Patterning of the surface of implantable devices for tissue growth management 失效
标题翻译：用于组织生长管理的可植入装置的表面的图案化
公开(公告)号：US20060020318A1
公开(公告)日：2006-01-26
申请号：US11159255
申请日：2005-06-23
申请人： Thomas Lenarz , John Parker , Dusan Milojevic
发明人： Thomas Lenarz , John Parker , Dusan Milojevic
IPC分类号： A61N1/05
CPC分类号： A61N1/0541
摘要： An implantable tissue-stimulating device for an implantee. The device comprising gate member having at least one electrode. At least a portion of the surface of the member having a configuration that at least partially controls any tissue growth on round the elongate member.
摘要翻译：用于植入物的可植入组织刺激装置。所述装置包括具有至少一个电极的栅极部件。该构件的表面的至少一部分具有至少部分地控制细长构件周围的任何组织生长的构造。

5. 发明授权

US08265773B2 Electrode assembly having a flexible tip 有权
标题翻译：具有柔性尖端的电极组件
公开(公告)号：US08265773B2
公开(公告)日：2012-09-11
申请号：US12911433
申请日：2010-10-25
申请人： Fysh Dadd , Derek Ian Darley , Peter Gibson , John Parker , Claudiu Treaba
发明人： Fysh Dadd , Derek Ian Darley , Peter Gibson , John Parker , Claudiu Treaba
IPC分类号： A61N1/05
CPC分类号： A61N1/0541 , A61F11/004
摘要： A cochlear implant electrode assembly device comprising an elongate electrode carrier member, a stiffening element, and a stiffening sheath that at least partially envelops the elongate member. The member is made of a resiliently flexible first material and has a plurality of electrodes mounted thereon. The member has a first configuration that allows it to be inserted into an implantee's cochlea. The member also has a second configuration wherein the member is curved to match an inside surface of the cochlea, and at least one intermediate configuration between the first and second configurations. Both the stiffening element and sheath are made of a material that is relatively stiffer than the member. The stiffening element and the stiffening sheath in combination bias the elongate member into the first configuration. If either the stiffening element or the stiffening sheath is removed or deactivated, the elongate member adopts an intermediate configuration.
摘要翻译：耳蜗植入电极组件装置，其包括细长的电极承载构件，加强元件和至少部分地包围细长构件的加强护套。该构件由弹性柔性的第一材料制成并且具有安装在其上的多个电极。该成员具有允许其插入到植入者的耳蜗中的第一配置。该构件还具有第二构造，其中构件弯曲以匹配耳蜗的内表面，以及在第一和第二构造之间的至少一个中间构造。加强元件和护套均由比构件相对较硬的材料制成。加强元件和加强护套组合地将细长构件偏置成第一构型。如果加强元件或加强护套被去除或去除，则细长构件采用中间构造。

6. 发明申请

US20110040364A1 ELECTRODE ASSEMBLY HAVING A FLEXIBLE TIP 有权
标题翻译：具有柔性提示的电极组件
公开(公告)号：US20110040364A1
公开(公告)日：2011-02-17
申请号：US12911433
申请日：2010-10-25
申请人： Fysh Dadd , Ian Darley , Peter Gibson , John Parker , Claudiu Treaba
发明人： Fysh Dadd , Ian Darley , Peter Gibson , John Parker , Claudiu Treaba
IPC分类号： A61F11/04 , A61N1/05
CPC分类号： A61N1/0541 , A61F11/004
摘要： A cochlear implant electrode assembly device comprising an elongate electrode carrier member, a stiffening element, and a stiffening sheath that at least partially envelops the elongate member. The member is made of a resiliently flexible first material and has a plurality of electrodes mounted thereon. The member has a first configuration that allows it to be inserted into an implantee's cochlea. The member also has a second configuration wherein the member is curved to match an inside surface of the cochlea, and at least one intermediate configuration between the first and second configurations. Both the stiffening element and sheath are made of a material that is relatively stiffer than the member. The stiffening element and the stiffening sheath in combination bias the elongate member into the first configuration. If either the stiffening element or the stiffening sheath is removed or deactivated, the elongate member adopts an intermediate configuration.
摘要翻译：耳蜗植入电极组件装置，其包括细长的电极承载构件，加强元件和至少部分地包围细长构件的加强护套。该构件由弹性柔性的第一材料制成并且具有安装在其上的多个电极。该成员具有允许其插入到植入者的耳蜗中的第一配置。该构件还具有第二构造，其中构件弯曲以匹配耳蜗的内表面，以及在第一和第二构造之间的至少一个中间构造。加强元件和护套均由比构件相对较硬的材料制成。加强元件和加强护套组合地将细长构件偏置成第一构型。如果加强元件或加强护套被去除或去除，则细长构件采用中间构造。

7. 发明申请

US20110022147A1 METHOD OF INSERTING AN ENDOSTEAL ELECTRODE 审中-公开
标题翻译：插入内皮电极的方法
公开(公告)号：US20110022147A1
公开(公告)日：2011-01-27
申请号：US12898574
申请日：2010-10-05
申请人： Peter Gibson , Ernst Lehnhardt , John Parker
发明人： Peter Gibson , Ernst Lehnhardt , John Parker
IPC分类号： A61F11/00 , A61N1/05
CPC分类号： A61N1/0541 , A61N1/36036
摘要： An implantable tissue-stimulating device comprising an elongate electrode carrier member (11) having a plurality of electrodes thereon. The carrier member (11) is preformed from a resiliently flexible biocompatible silicone and extends from a distal end (12) to a stop member (13). The carrier member (11) is adapted for intracochlear but extraluminar insertion within the cochlea of an implantee. The placement of the carrier member (11) is designed to avoid any breach of the internal ducts of the cochlea (20), such as the scala tympani (24) and scala vestibuli (25) so that the normal hydrodynamic behavior of the cochlea (20) is not affected by any intrusive device. Use of the device in a system for masking or treating the symptoms of tinnitus is also described.
摘要翻译：一种可植入组织刺激装置，包括在其上具有多个电极的细长电极载体构件（11）。载体构件（11）由弹性柔性的生物相容性硅树脂预成型，并从远端（12）延伸到止动构件（13）。载体构件（11）适于在植入物的耳蜗内进行耳内但外源性插入。载体构件（11）的放置被设计成避免耳蜗（20）的内部管道的任何破坏，例如鼓膜鼓膜（24）和沙拉前庭（25），使得耳蜗的正常流体动力学行为 20）不受任何侵入设备的影响。还描述了在用于掩蔽或治疗耳鸣症状的系统中使用该装置。

8. 发明授权

US07063708B2 Insertion tool system for an electrode array 有权
标题翻译：电极阵列插入工具系统
公开(公告)号：US07063708B2
公开(公告)日：2006-06-20
申请号：US10344400
申请日：2002-03-19
申请人： Peter Gibson , John Parker , Claudiu Treaba
发明人： Peter Gibson , John Parker , Claudiu Treaba
IPC分类号： A61B19/00
CPC分类号： A61N1/0541 , A61B17/3468 , A61B2017/00787
摘要： A device (10) used for inserting an electrode array (15) into a cochlea of a subject. Particularly, the device (10) is adapted for insertion of electrode arrays (15) having an elongate carrier member (21) and a removable stylet (22) extending through the carrier member (21). The device includes a handle (11), an elongate positioning member (12) mounted to the handle (11), an actuator member (17) movable relative to the elongate positioning member (12), and at least one anchor member (16) connected to the actuator member (17) and engageable with the removable stylet (22). On insertion of the electrode array (15) into a subject's cochlea, the actuator member (17) can be moved relative to the elongate positioning member (12) to withdraw the removable stylet (22) from the carrier member.
摘要翻译：一种用于将电极阵列（15）插入到对象的耳蜗中的装置（10）。特别地，装置（10）适于插入具有延伸穿过承载构件（21）的细长承载构件（21）和可移除探针（22）的电极阵列（15）。所述装置包括手柄（11），安装到手柄（11）的细长定位构件（12），可相对于细长定位构件（12）移动的致动器构件（17）和至少一个锚定构件（16）连接到致动器构件（17）并且可与可移除的探针（22）接合。在将电极阵列（15）插入到被检者的耳蜗中时，致动器构件（17）可以相对于细长定位构件（12）移动，以从承载构件撤回可移除的探针（22）。

9. 发明申请

US20060079950A1 Cochlear endosteal electrode carrier member 失效
标题翻译：耳蜗内膜电极载体构件
公开(公告)号：US20060079950A1
公开(公告)日：2006-04-13
申请号：US11125171
申请日：2005-05-10
申请人： Ernst Lehnhardt , Horst Hessel , Peter Gibson , John Parker , Ernst von Wallenberg
发明人： Ernst Lehnhardt , Horst Hessel , Peter Gibson , John Parker , Ernst von Wallenberg
IPC分类号： A61N1/05
CPC分类号： A61N1/0541
摘要： An elongate electrode carrier member for implantation in a location external to the cochlear canals to position at least one, and likely many, electrodes sufficiently proximate to the organ of Corti to effectively deliver stimulation signals to the auditory nerve fibers of the cochlear. Generally, the carrier member is dimensioned to be implanted in a crevice, channel or pocket formed between the spiral ligament and bony capsule of the cochlear. Embodiments of the carrier member preferably have a minimized volume to accommodate insertion into such a crevice. In addition, embodiments of the carrier member comprise an elongate bulbous central region having electrodes disposed on the medial surface thereof, and elongate tapered side regions laterally extending from the central region. The side regions have rounded edges and are preferably flexible, while the carrier is configured to coil or turn toward the medial surface. This construction facilitates implantation of the carrier member: the carrier member has sufficient longitudinal strength to maintain its form and direction while being pushed into the surgically-formed crevice, and coils in a longitudinal plane to follow the contour of the cochlear, while the side regions serve to guide the direction of travel, flexing out of the lateral plane as necessary to avoid damaging anatomical structures. Once implanted, embodiments of the carrier member are urged to remain in its implanted position due to one or more of either the side regions extending into the corners of the crevice, and/or due to the curved lateral surface of the carrier member which approximates the curvature of the endosteum along the basal turn of the cochlea.
摘要翻译：一种用于植入耳蜗通道外部位置的细长电极载体部件，以将至少一个足够靠近Corti器官的电极定位并且可能地许多，以有效地将刺激信号传递到耳蜗的听觉神经纤维。通常，载体构件的尺寸被设计成植入形成在耳蜗的螺旋韧带和骨膜之间的缝隙，通道或口袋。承载构件的实施例优选地具有最小的体积以适应插入到这样的缝隙中。此外，载体构件的实施例包括细长的球状中心区域，其具有设置在其内表面上的电极和从中心区域横向延伸的细长锥形侧区域。侧部区域具有圆形边缘并且优选地是柔性的，而载体构造成朝向内侧表面线圈或转向。这种构造便于载体构件的植入：载体构件具有足够的纵向强度以在被推入手术形成的缝隙中时保持其形状和方向，并且在纵向平面中线圈遵循耳蜗的轮廓，而侧面区域用于引导行进方向，根据需要从侧向平面弯曲，以避免损伤解剖结构。一旦被植入，承载构件的实施例被推动以保持在其植入位置，这是由于侧壁区域中的一个或多个延伸到缝隙的角部和/或由于承载构件的弯曲侧表面近似于耳蜗沿耳蜗基底转弯的曲率。

10. 发明授权

US07451000B2 Pre-curved cochlear implant electrode array 有权
标题翻译：预弯曲耳蜗植入电极阵列
公开(公告)号：US07451000B2
公开(公告)日：2008-11-11
申请号：US10332515
申请日：2001-11-28
申请人： Peter Gibson , Fysh Dadd , Claudiu Treaba , John Parker
发明人： Peter Gibson , Fysh Dadd , Claudiu Treaba , John Parker
IPC分类号： A61N1/05 , B28B5/00
CPC分类号： A61N1/0541 , A61F11/004 , B28B5/00
摘要： An implantable electrode array (30) that can adopt a first configuration selected to allow the array (30) to be inserted into a cochlea (12) of an implantee and at least a second configuration in which the array can apply tissue stimulation. The array (30) comprises an elongate carrier (31) having a proximal end (37), a distal end (34), and an inner surface (35) conformable with the inner wall of the implantee's cochlea (12). A plurality of electrodes (36) are supported within the carrier (31) at respective spaced locations thereon in a region between the proximal end (37) and the distal end (34) with at least one of the electrodes having a surface that is at least adjacent the inner surface (35) of the carrier (31). The carrier (31) is formed in the second configuration from a first layer (32) and at least a second layer (32) of resiliently flexible material. A method of forming an array (30) is also described.
摘要翻译：可植入电极阵列（30），其可以采用被选择以允许阵列（30）插入到植入物的耳蜗（12）中的第一配置和至少第二配置，其中阵列可以应用组织刺激。阵列（30）包括具有近端（37），远端（34）和与被植入物的耳蜗（12）的内壁相适合的内表面（35）的细长载体（31）。在近端（37）和远端（34）之间的区域中，多个电极（36）被支撑在载体（31）内的相应间隔位置处，其中至少一个电极具有处于最不邻近载体（31）的内表面（35）。载体（31）由第一层（32）和至少第二层（32）形成为弹性柔性材料。还描述了形成阵列（30）的方法。

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