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1. 发明授权

US07894916B2 Insertion tool for a cochlear implant electrode array 失效
标题翻译：用于耳蜗植入电极阵列的插入工具
公开(公告)号：US07894916B2
公开(公告)日：2011-02-22
申请号：US10203079
申请日：2001-10-17
申请人： Peter Gibson , Ian Darley , Claudiu Treaba , John Parker , Fysh Dadd
发明人： Peter Gibson , Ian Darley , Claudiu Treaba , John Parker , Fysh Dadd
IPC分类号： A61N1/05
CPC分类号： A61N1/0541 , A61F11/004
摘要： A cochlear implant electrode assembly device (10) comprising an elongate electrode carrier member (11), and a shape element (15) formed of a memory material, such as Nitinol. The elongate member (11) is made of a resiliently flexible first material and has a length and a plurality of electrodes (12) mounted thereon adapted to apply a preselected tissue stimulation. The elongate member (11) has a pre-formed curved orientation that at least substantially matches an inside surface of a cochlea, an implantable orientation different to said pre-formed orientation that allows said member to be inserted into an implantee's cochlea, and an at least one intermediate orientation between said implantable orientation and said pre-formed orientation. The shape element (15) is removably positioned within the elongate member (11) and extends along at least a portion of the length thereof. The shape element (15) has a first shape selected for biasing the elongate member (11) into the implantable orientation when the shape element is at a first temperature, and at least a second shape that allows the elongate member (11) to adopt said at least one intermediate orientation when the shape element (15) is exposed to a temperature of the cochlea (30) being different than the first temperature.
摘要翻译：一种包括细长电极载体构件（11）的耳蜗植入电极组件装置（10）和由诸如镍钛诺的记忆材料形成的形状元件（15）。细长构件（11）由弹性柔性的第一材料制成并且具有安装在其上的长度和多个电极（12），适于施加预选的组织刺激。细长构件（11）具有预先形成的弯曲取向，其至少基本上匹配耳蜗的内表面，不同于允许所述构件插入到植入物的耳蜗中的所述预形成取向的可植入取向，以及在在所述可植入取向和所述预成形取向之间的至少一个中间取向。形状元件（15）可移除地定位在细长构件（11）内并沿其长度的至少一部分延伸。当形状元件处于第一温度时，形状元件（15）具有被选择用于将细长构件（11）偏置成可植入取向的第一形状，以及至少第二形状，其允许细长构件（11）采用所述当形状元件（15）暴露于与第一温度不同的耳蜗（30）的温度时，至少一个中间取向。

2. 发明申请

US20080269864A1 Cochlear implant electrode array 有权
标题翻译：人工耳蜗植入电极阵列
公开(公告)号：US20080269864A1
公开(公告)日：2008-10-30
申请号：US11857234
申请日：2007-09-18
申请人： Fysh Dadd , Ian Darley , Peter Gibson , John Parker , Claudiu Treaba
发明人： Fysh Dadd , Ian Darley , Peter Gibson , John Parker , Claudiu Treaba
IPC分类号： A61N1/00
CPC分类号： A61N1/0541 , A61F11/004
摘要： A cochlear implant electrode assembly (10) comprising an elongate electrode carrier member (11), a bioresorbable stiffening element (15) and an outer layer (16) surrounding the stiffening element (15). The carrier member (11) is made of a resiliently flexible first material and has a plurality of electrodes (12) mounted thereon and has a first configuration selected to allow it to be inserted into an implantee's cochlea, and at least a second configuration wherein it is curved to match a surface of the cochlea. The bioresorbable stiffening element (15) has a configuration selected for biasing the elongate member (11) into the first configuration and is made of a second material relatively stiffer than the first material and which dissolves or softens on exposure to cochlear fluids to permit the elongate member (11) to at least approach or adopt the second configuration. The outer layer (16) surrounding the stiffening element (15) is made of a material sufficiently resiliently flexible to allow the elongate member (11) to at least approach or adopt the second configuration. The outer layer (16) has a first rate of cochlear fluid ingress therethrough and has at least one fluid ingress means (21) formed therein. The rate of cochlear fluid ingress through the fluid ingress means (21) is greater than the first rate of cochlear fluid ingress through the outer layer (16).
摘要翻译：耳蜗植入电极组件（10）包括细长电极载体构件（11），生物可再吸收加强元件（15）和围绕加强元件（15）的外层（16）。载体构件（11）由弹性柔性的第一材料制成并且具有安装在其上的多个电极（12），并且具有选择为允许其插入植入物的耳蜗中的第一构型，以及至少第二构型，其中弯曲以匹配耳蜗的表面。生物可再吸收加强元件（15）具有被选择用于将细长构件（11）偏置成第一构造并由比第一材料更硬的第二材料制成并且在暴露于耳蜗流体时溶解或软化以允许细长成员（11）至少接近或采用第二种配置。围绕加强元件（15）的外层（16）由足够弹性地柔性的材料制成，以允许细长构件（11）至少接近或采用第二构型。外层（16）具有第一速率的耳蜗流体穿过其中并具有形成在其中的至少一个流体入口装置（21）。通过流体入口装置（21）进入的耳蜗流体的速率大于通过外层（16）进入的第一速率的人工耳蜗流体。

3. 发明申请

US20070073371A1 Combination stylet and sheath for an electrode array 有权
标题翻译：用于电极阵列的组合探针和护套
公开(公告)号：US20070073371A1
公开(公告)日：2007-03-29
申请号：US11604338
申请日：2006-11-27
申请人： Fysh Dadd , Ian Darley , Peter Gibson , John Parker , Claudiu Treaba
发明人： Fysh Dadd , Ian Darley , Peter Gibson , John Parker , Claudiu Treaba
IPC分类号： A61N1/36
CPC分类号： A61N1/0541 , A61F11/004
摘要： A cochlear implant electrode assembly device (10) comprising an elongate electrode carrier member (11), a stiffening element (15), and a stiffening sheath (16) that at least partially envelops the elongate member (11). The member (11) is made of a resiliently flexible first material and has a plurality of electrodes (12) mounted thereon. The member (11) has a first configuration that allows it to be inserted into an implantee's cochlea (30). The member (11) also has a second configuration wherein the member is curved to match an inside surface of the cochlea (30), and at least one intermediate configuration between the first and second configurations. Both the stiffening element (15) and sheath (16) are made of a material that is relatively stiffer than the member (11). The stiffening element (15) and the stiffening sheath (16) in combination bias the elongate member (11) into the first configuration. If either the stiffening element (15) or the stiffening sheath (16) is removed or deactivated, the elongate member (11) adopts an intermediate configuration.
摘要翻译：耳蜗植入电极组件装置（10）包括细长电极载体构件（11），加强元件（15）和至少部分地包围细长构件（11）的加强护套（16）。构件（11）由弹性柔性的第一材料制成并且具有安装在其上的多个电极（12）。构件（11）具有允许其插入到植入物的耳蜗（30）中的第一构造。构件（11）还具有第二构造，其中构件弯曲以匹配耳蜗（30）的内表面，以及在第一和第二构造之间的至少一个中间构造。加强元件（15）和护套（16）均由比构件（11）相对更硬的材料制成。加强元件（15）和加强护套（16）组合地将细长构件（11）偏置成第一构型。如果加强元件（15）或加强护套（16）被去除或停用，则细长构件（11）采用中间构造。

4. 发明授权

US07146227B2 Combination stylet and straightening coating for a cochlear implant electrode array 有权
标题翻译：用于耳蜗植入电极阵列的组合探针和矫直涂层
公开(公告)号：US07146227B2
公开(公告)日：2006-12-05
申请号：US10149643
申请日：2001-09-28
申请人： Fysh Dadd , Ian Darley , Peter Gibson , John Parker , Claudiu Treaba
发明人： Fysh Dadd , Ian Darley , Peter Gibson , John Parker , Claudiu Treaba
IPC分类号： A61N1/05
CPC分类号： A61N1/0541 , A61F11/004
摘要： A cochlear implant electrode assembly device (10) comprising an elongate electrode carrier member (11), a stiffening element (15), and a stiffening sheath (16) that at least partially envelops the elongate member (11). The member (11) is made of a resiliently flexible first material and has a plurality of electrodes (12) mounted thereon. The member (11) has a first configuration that allows it to be inserted into an implantee's cochlea (30). The member (11) also has a second configuration wherein the member is curved to match an inside surface of the cochlea (30), and at least one intermediate configuration between the first and second configurations. Both the stiffening element (15) and sheath (16) are made of a material that is relatively stiffer than the member (11). The stiffening element (15) and the stiffening sheath (16) in combination bias the elongate member (11) into the first configuration. If either the stiffening element (15) or the stiffening sheath (16) is removed or deactivated, the elongate member (11) adopts an intermediate configuration.
摘要翻译：耳蜗植入电极组件装置（10）包括细长电极载体构件（11），加强元件（15）和至少部分地包围细长构件（11）的加强护套（16）。构件（11）由弹性柔性的第一材料制成并且具有安装在其上的多个电极（12）。构件（11）具有允许其插入到植入物的耳蜗（30）中的第一构造。构件（11）还具有第二构造，其中构件弯曲以匹配耳蜗（30）的内表面，以及在第一和第二构造之间的至少一个中间构造。加强元件（15）和护套（16）均由比构件（11）相对更硬的材料制成。加强元件（15）和加强护套（16）组合地将细长构件（11）偏置成第一构型。如果加强元件（15）或加强护套（16）被去除或停用，则细长构件（11）采用中间构造。

5. 发明授权

US07272449B2 Cochlear implant electrode array 有权
标题翻译：人工耳蜗植入电极阵列
公开(公告)号：US07272449B2
公开(公告)日：2007-09-18
申请号：US10149642
申请日：2001-09-28
申请人： Fysh Dadd , Ian Darley , Peter Gibson , John Parker , Claudiu Treaba
发明人： Fysh Dadd , Ian Darley , Peter Gibson , John Parker , Claudiu Treaba
IPC分类号： A61N1/05
CPC分类号： A61N1/0541 , A61F11/004
摘要： A cochlear implant electrode assembly (10) comprising an elongate electrode carrier member (11), a bioresorbable stiffening element (15) and an outer layer (16) surrounding the stiffening element (15). The carrier member (11) is made of a resiliently flexible first material and has a plurality of electrodes (12) mounted thereon and has a first configuration selected to allow it to be inserted into an implantee's cochlea, and at least a second configuration wherein it is curved to match a surface of the cochlea. The bioresorbable stiffening element (15) has a configuration selected for biassing the elongate member (11) into the first configuratin and is made of a second material relatively stiffer than the first material and which dissolves or softens on exposure to cochlear fluids to permit the elongate member (11) to at least approach or adopt the second configuration. The outer layer (16) surrounding the stiffening element (15) is made of a material sufficiently resiliently flexible to allow the elongate member (11) to at least approach or adopt the second configuration. The outer layer (16) has a first rate of cochlear fluid ingress therethrough and has at least one fluid ingress means (21) formed therein. The rate of cochlear fluid ingress through the fluid ingress means (21) is greater than the first rate of cochlear fluid ingress through the outer layer (16).
摘要翻译：耳蜗植入电极组件（10）包括细长电极载体构件（11），生物可再吸收加强元件（15）和围绕加强元件（15）的外层（16）。载体构件（11）由弹性柔性的第一材料制成并且具有安装在其上的多个电极（12），并且具有选择为允许其插入植入物的耳蜗中的第一构型，以及至少第二构型，其中弯曲以匹配耳蜗的表面。生物可吸收加强元件（15）具有选择用于将细长构件（11）偏置到第一配置中的构造，并且由比第一材料相对更硬的第二材料制成并且在暴露于耳蜗流体时溶解或软化以允许细长成员（11）至少接近或采用第二种配置。围绕加强元件（15）的外层（16）由足够弹性地柔性的材料制成，以允许细长构件（11）至少接近或采用第二构型。外层（16）具有第一速率的耳蜗流体穿过其中并具有形成在其中的至少一个流体入口装置（21）。通过流体入口装置（21）进入的耳蜗流体的速率大于通过外层（16）进入的第一速率的人工耳蜗流体。

6. 发明授权

US08265773B2 Electrode assembly having a flexible tip 有权
标题翻译：具有柔性尖端的电极组件
公开(公告)号：US08265773B2
公开(公告)日：2012-09-11
申请号：US12911433
申请日：2010-10-25
申请人： Fysh Dadd , Derek Ian Darley , Peter Gibson , John Parker , Claudiu Treaba
发明人： Fysh Dadd , Derek Ian Darley , Peter Gibson , John Parker , Claudiu Treaba
IPC分类号： A61N1/05
CPC分类号： A61N1/0541 , A61F11/004
摘要： A cochlear implant electrode assembly device comprising an elongate electrode carrier member, a stiffening element, and a stiffening sheath that at least partially envelops the elongate member. The member is made of a resiliently flexible first material and has a plurality of electrodes mounted thereon. The member has a first configuration that allows it to be inserted into an implantee's cochlea. The member also has a second configuration wherein the member is curved to match an inside surface of the cochlea, and at least one intermediate configuration between the first and second configurations. Both the stiffening element and sheath are made of a material that is relatively stiffer than the member. The stiffening element and the stiffening sheath in combination bias the elongate member into the first configuration. If either the stiffening element or the stiffening sheath is removed or deactivated, the elongate member adopts an intermediate configuration.
摘要翻译：耳蜗植入电极组件装置，其包括细长的电极承载构件，加强元件和至少部分地包围细长构件的加强护套。该构件由弹性柔性的第一材料制成并且具有安装在其上的多个电极。该成员具有允许其插入到植入者的耳蜗中的第一配置。该构件还具有第二构造，其中构件弯曲以匹配耳蜗的内表面，以及在第一和第二构造之间的至少一个中间构造。加强元件和护套均由比构件相对较硬的材料制成。加强元件和加强护套组合地将细长构件偏置成第一构型。如果加强元件或加强护套被去除或去除，则细长构件采用中间构造。

7. 发明申请

US20110040364A1 ELECTRODE ASSEMBLY HAVING A FLEXIBLE TIP 有权
标题翻译：具有柔性提示的电极组件
公开(公告)号：US20110040364A1
公开(公告)日：2011-02-17
申请号：US12911433
申请日：2010-10-25
申请人： Fysh Dadd , Ian Darley , Peter Gibson , John Parker , Claudiu Treaba
发明人： Fysh Dadd , Ian Darley , Peter Gibson , John Parker , Claudiu Treaba
IPC分类号： A61F11/04 , A61N1/05
CPC分类号： A61N1/0541 , A61F11/004
摘要： A cochlear implant electrode assembly device comprising an elongate electrode carrier member, a stiffening element, and a stiffening sheath that at least partially envelops the elongate member. The member is made of a resiliently flexible first material and has a plurality of electrodes mounted thereon. The member has a first configuration that allows it to be inserted into an implantee's cochlea. The member also has a second configuration wherein the member is curved to match an inside surface of the cochlea, and at least one intermediate configuration between the first and second configurations. Both the stiffening element and sheath are made of a material that is relatively stiffer than the member. The stiffening element and the stiffening sheath in combination bias the elongate member into the first configuration. If either the stiffening element or the stiffening sheath is removed or deactivated, the elongate member adopts an intermediate configuration.
摘要翻译：耳蜗植入电极组件装置，其包括细长的电极承载构件，加强元件和至少部分地包围细长构件的加强护套。该构件由弹性柔性的第一材料制成并且具有安装在其上的多个电极。该成员具有允许其插入到植入者的耳蜗中的第一配置。该构件还具有第二构造，其中构件弯曲以匹配耳蜗的内表面，以及在第一和第二构造之间的至少一个中间构造。加强元件和护套均由比构件相对较硬的材料制成。加强元件和加强护套组合地将细长构件偏置成第一构型。如果加强元件或加强护套被去除或去除，则细长构件采用中间构造。

8. 发明授权

US07983767B2 Cochlear implant electrode array 有权
标题翻译：人工耳蜗植入电极阵列
公开(公告)号：US07983767B2
公开(公告)日：2011-07-19
申请号：US11857234
申请日：2007-09-18
申请人： Fysh Dadd , Derek Ian Darley , Peter Gibson , John Parker , Claudiu Treaba
发明人： Fysh Dadd , Derek Ian Darley , Peter Gibson , John Parker , Claudiu Treaba
IPC分类号： A61N1/05
CPC分类号： A61N1/0541 , A61F11/004
摘要： A cochlear implant electrode assembly (10) comprising an elongate electrode carrier member (11), a bioresorbable stiffening element (15) and an outer layer (16) surrounding the stiffening element (15). The carrier member (11) is made of a resiliently flexible first material and has a plurality of electrodes (12) mounted thereon and has a first configuration selected to allow it to be inserted into an implantee's cochlea, and at least a second configuration wherein it is curved to match a surface of the cochlea. The bioresorbable stiffening element (15) has a configuration selected for biasing the elongate member (11) into the first configuration and is made of a second material relatively stiffer than the first material and which dissolves or softens on exposure to cochlear fluids to permit the elongate member (11) to at least approach or adopt the second configuration. The outer layer (16) surrounding the stiffening element (15) is made of a material sufficiently resiliently flexible to allow the elongate member (11) to at least approach or adopt the second configuration. The outer layer (16) has a first rate of cochlear fluid ingress therethrough and has at least one fluid ingress means (21) formed therein. The rate of cochlear fluid ingress through the fluid ingress means (21) is greater than the first rate of cochlear fluid ingress through the outer layer (16).
摘要翻译：耳蜗植入电极组件（10）包括细长电极载体构件（11），生物可再吸收加强元件（15）和围绕加强元件（15）的外层（16）。载体构件（11）由弹性柔性的第一材料制成并且具有安装在其上的多个电极（12），并且具有选择为允许其插入植入物的耳蜗中的第一构型，以及至少第二构型，其中弯曲以匹配耳蜗的表面。生物可再吸收加强元件（15）具有被选择用于将细长构件（11）偏置成第一构造并由比第一材料更硬的第二材料制成并且在暴露于耳蜗流体时溶解或软化以允许细长成员（11）至少接近或采用第二种配置。围绕加强元件（15）的外层（16）由足够弹性地柔性的材料制成，以允许细长构件（11）至少接近或采用第二构型。外层（16）具有第一速率的耳蜗流体穿过其中并具有形成在其中的至少一个流体入口装置（21）。通过流体入口装置（21）进入的耳蜗流体的速率大于通过外层（16）进入的第一速率的人工耳蜗流体。

9. 发明授权

US07974712B2 Pre-curved cochlear implant electrode array 有权
标题翻译：预弯曲耳蜗植入电极阵列
公开(公告)号：US07974712B2
公开(公告)日：2011-07-05
申请号：US12250413
申请日：2008-10-13
申请人： Peter Gibson , Fysh Dadd , Claudiu Treaba , John Parker
发明人： Peter Gibson , Fysh Dadd , Claudiu Treaba , John Parker
IPC分类号： A61N1/05 , B28B5/00
CPC分类号： A61N1/0541 , A61F11/004 , B28B5/00
摘要： An implantable electrode array (30) that can adopt a first configuration selected to allow the array (30) to be inserted into a cochlea (12) of an implantee and at least a second configuration in which the array can apply tissue stimulation. The array (30) comprises an elongate carrier (31) having a proximal end (37), a distal end (34), and an inner surface (35) conformable with the inner wall of the implantee's cochlea (12). A plurality of electrodes (36) are supported within the carrier (31) at respective spaced locations thereon in a region between the proximal end (37) and the distal end (34) with at least one of the electrodes having a surface that is at least adjacent the inner surface (35) of the carrier (31). The carrier (31) is formed in the second configuration from a first layer (32) and at least a second layer (32) of resiliently flexible material. A method of forming an array (30) is also described.
摘要翻译：可植入电极阵列（30），其可以采用被选择以允许阵列（30）插入到植入物的耳蜗（12）中的第一配置和至少第二配置，其中阵列可以应用组织刺激。阵列（30）包括具有近端（37），远端（34）和与被植入物的耳蜗（12）的内壁相适合的内表面（35）的细长载体（31）。在近端（37）和远端（34）之间的区域中，多个电极（36）被支撑在载体（31）内的相应间隔位置处，其中至少一个电极具有处于最不邻近载体（31）的内表面（35）。载体（31）由第一层（32）和至少第二层（32）形成为弹性柔性材料。还描述了形成阵列（30）的方法。

10. 发明授权

US08620459B2 Pre-curved cochlear implant electrode array 有权
标题翻译：预弯曲耳蜗植入电极阵列
公开(公告)号：US08620459B2
公开(公告)日：2013-12-31
申请号：US13175853
申请日：2011-07-03
申请人： Peter Gibson , Fysh Dadd , Claudiu Treaba , John Parker
发明人： Peter Gibson , Fysh Dadd , Claudiu Treaba , John Parker
IPC分类号： A61N1/05 , B28B5/00
CPC分类号： A61N1/0541 , A61F11/004 , B28B5/00
摘要： An implantable electrode array (30) that can adopt a first configuration selected to allow the array (30) to be inserted into a cochlea (12) of an implantee and at least a second configuration in which the array can apply tissue stimulation. The array (30) comprises an elongate carrier (31) having a proximal end (37), a distal end (34), and an inner surface (35) conformable with the inner wall of the implantee's cochlea (12). A plurality of electrodes (36) are supported within the carrier (31) at respective spaced locations thereon in a region between the proximal end (37) and the distal end (34) with at least one of the electrodes having a surface that is at least adjacent the inner surface (35) of the carrier (31). The carrier (31) is formed in the second configuration from a first layer (32) and at least a second layer (32) of resiliently flexible material. Manufacturing methods include molding the first and second layers into an array such as that described above.
摘要翻译：可植入电极阵列（30），其可以采用被选择以允许阵列（30）插入到植入物的耳蜗（12）中的第一配置和至少第二配置，其中阵列可以应用组织刺激。阵列（30）包括具有近端（37），远端（34）和与被植入物的耳蜗（12）的内壁相适合的内表面（35）的细长载体（31）。在近端（37）和远端（34）之间的区域中，多个电极（36）被支撑在载体（31）内的相应间隔位置处，其中至少一个电极具有处于最不邻近载体（31）的内表面（35）。载体（31）由第一层（32）和至少第二层（32）形成为弹性柔性材料。制造方法包括将第一层和第二层模制成如上所述的阵列。

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