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1. 发明申请

US20050004627A1 Auditory midbrain implant 有权
标题翻译：听觉中脑植入
公开(公告)号：US20050004627A1
公开(公告)日：2005-01-06
申请号：US10493675
申请日：2002-10-25
申请人： Peter Gibson , Thomas Lenarz , Minoo Lenarz , Miro Mackiewicz , John Parker , James Patrick
发明人： Peter Gibson , Thomas Lenarz , Minoo Lenarz , Miro Mackiewicz , John Parker , James Patrick
IPC分类号： A61F11/04 , A61N1/05
CPC分类号： A61N1/0529 , A61F11/04 , A61N1/0541 , A61N1/36036
摘要： An electrode array (10) that is implantable within the inferior colliculus of the midbrain and/or other appropriate regions of the brain of an implantee and adapted to provide electrical stimulation thereto. The electrode array (10) an elongate member (11) having a plurality of electrodes (12) mounted thereon in a longitudinal array. A delivery cannula (30) for delivering the electrode array (10) comprised of two half-pipes (31) is also described.
摘要翻译：电极阵列（10），其可植入在植入物的脑的中脑和/或其它适当区域的下丘丘内，并适于对其施加电刺激。电极阵列（10）具有以纵向阵列安装在其上的多个电极（12）的细长构件（11）。还描述了用于输送由两个半管（31）组成的电极阵列（10）的输送插管（30）。

2. 发明授权

US07797029B2 Auditory midbrain implant 有权
标题翻译：听觉中脑植入
公开(公告)号：US07797029B2
公开(公告)日：2010-09-14
申请号：US10493675
申请日：2002-10-25
申请人： Peter Gibson , Thomas Lenarz , Minoo Lenarz , Miro Mackiewicz , John Parker , James Finlay Patrick
发明人： Peter Gibson , Thomas Lenarz , Minoo Lenarz , Miro Mackiewicz , John Parker , James Finlay Patrick
IPC分类号： A61B5/04 , A61N1/18 , A61N1/05
CPC分类号： A61N1/0529 , A61F11/04 , A61N1/0541 , A61N1/36036
摘要： An electrode array that is implantable within the inferior colliculus of the midbrain and/or other appropriate regions of the brain of an implantee and adapted to provide electrical stimulation thereto. The electrode array an elongate member having a plurality of electrodes mounted thereon in a longitudinal array. A delivery cannula for delivering the electrode array comprised of two half-pipes is also described.
摘要翻译：可植入在植入物的脑的中脑和/或其他适当区域的下丘中并适于对其施加电刺激的电极阵列。电极阵列具有纵向阵列中安装有多个电极的细长构件。还描述了用于输送由两个半管构成的电极阵列的输送插管。

3. 发明授权

US07983767B2 Cochlear implant electrode array 有权
标题翻译：人工耳蜗植入电极阵列
公开(公告)号：US07983767B2
公开(公告)日：2011-07-19
申请号：US11857234
申请日：2007-09-18
申请人： Fysh Dadd , Derek Ian Darley , Peter Gibson , John Parker , Claudiu Treaba
发明人： Fysh Dadd , Derek Ian Darley , Peter Gibson , John Parker , Claudiu Treaba
IPC分类号： A61N1/05
CPC分类号： A61N1/0541 , A61F11/004
摘要： A cochlear implant electrode assembly (10) comprising an elongate electrode carrier member (11), a bioresorbable stiffening element (15) and an outer layer (16) surrounding the stiffening element (15). The carrier member (11) is made of a resiliently flexible first material and has a plurality of electrodes (12) mounted thereon and has a first configuration selected to allow it to be inserted into an implantee's cochlea, and at least a second configuration wherein it is curved to match a surface of the cochlea. The bioresorbable stiffening element (15) has a configuration selected for biasing the elongate member (11) into the first configuration and is made of a second material relatively stiffer than the first material and which dissolves or softens on exposure to cochlear fluids to permit the elongate member (11) to at least approach or adopt the second configuration. The outer layer (16) surrounding the stiffening element (15) is made of a material sufficiently resiliently flexible to allow the elongate member (11) to at least approach or adopt the second configuration. The outer layer (16) has a first rate of cochlear fluid ingress therethrough and has at least one fluid ingress means (21) formed therein. The rate of cochlear fluid ingress through the fluid ingress means (21) is greater than the first rate of cochlear fluid ingress through the outer layer (16).
摘要翻译：耳蜗植入电极组件（10）包括细长电极载体构件（11），生物可再吸收加强元件（15）和围绕加强元件（15）的外层（16）。载体构件（11）由弹性柔性的第一材料制成并且具有安装在其上的多个电极（12），并且具有选择为允许其插入植入物的耳蜗中的第一构型，以及至少第二构型，其中弯曲以匹配耳蜗的表面。生物可再吸收加强元件（15）具有被选择用于将细长构件（11）偏置成第一构造并由比第一材料更硬的第二材料制成并且在暴露于耳蜗流体时溶解或软化以允许细长成员（11）至少接近或采用第二种配置。围绕加强元件（15）的外层（16）由足够弹性地柔性的材料制成，以允许细长构件（11）至少接近或采用第二构型。外层（16）具有第一速率的耳蜗流体穿过其中并具有形成在其中的至少一个流体入口装置（21）。通过流体入口装置（21）进入的耳蜗流体的速率大于通过外层（16）进入的第一速率的人工耳蜗流体。

4. 发明授权

US07974711B2 Double stylet insertion tool for a cochlear implant electrode array 有权
标题翻译：用于耳蜗植入电极阵列的双探针插入工具
公开(公告)号：US07974711B2
公开(公告)日：2011-07-05
申请号：US11853641
申请日：2007-09-11
申请人： Fysh Dadd , Derek I. Darley , Peter Gibson , John Parker , Claudiu Treaba
发明人： Fysh Dadd , Derek I. Darley , Peter Gibson , John Parker , Claudiu Treaba
IPC分类号： A61N1/05
CPC分类号： A61N1/0541 , A61F11/004
摘要： A cochlear implant electrode assembly device (10) comprising an elongate electrode carrier member (11), a first stiffening element (15a), and a second stiffening element (15b). The carrier member (11) is made of a resiliently flexible first material and has a plurality of electrodes (12) mounted thereon. The carrier member (11) has a first configuration selected to allow it to be inserted into an implantee's cochlea (30), a second configuration wherein it is curved in shape to match a surface of the cochlea (30), and at least one intermediate configuration between the first and second configurations. Both the first and second stiffening elements (15a,15b) are made of a material relatively stiffer than said the material and in combination bias the elongate member into the first configuration. If either the first stiffening element (15a) or the second stiffening element (15b) are removed, the elongate member (11) adopts the at least one intermediate configuration.
摘要翻译：耳蜗植入电极组件装置（10）包括细长电极载体构件（11），第一加强元件（15a）和第二加强元件（15b）。载体构件（11）由弹性柔性的第一材料制成并且具有安装在其上的多个电极（12）。载体构件（11）具有被选择为允许其插入到植入物的耳蜗（30）中的第一构型，第二构造，其弯曲形状以匹配耳蜗（30）的表面，并且至少一个中间体配置在第一和第二配置之间。第一和第二加强元件（15a，15b）都由比所述材料相对更硬的材料制成并且将细长构件组合地偏压到第一构造中。如果去除第一加强元件（15a）或第二加强元件（15b），则细长构件（11）采用至少一个中间构造。

5. 发明授权

US07962226B2 Cochlear endosteal electrode carrier member 失效
标题翻译：耳蜗内膜电极载体构件
公开(公告)号：US07962226B2
公开(公告)日：2011-06-14
申请号：US11125171
申请日：2005-05-10
申请人： Ernst Lehnhardt , Horst Hessel , Peter Gibson , John Parker , Ernst von Wallenberg
发明人： Ernst Lehnhardt , Horst Hessel , Peter Gibson , John Parker , Ernst von Wallenberg
IPC分类号： A61N1/05
CPC分类号： A61N1/0541
摘要： An elongate electrode carrier member including a longitudinally-extending central region, two side regions laterally extending from opposing sides of the central region, a lateral surface defined by the central and side regions together forming a convex circumferential surface, a medial surface defined by a convex surface of the central region and a concave surface for each of the side regions, a plurality of longitudinally-spaced electrodes disposed on or in the convex surface of the central region of the medial surface, and a support structure including a plurality of longitudinally extending wires each connected to one or more of the electrodes, wherein a subset of the plurality of wires is disposed in the central region and at least one of the plurality of wires is disposed in one of the side regions.
摘要翻译：细长电极载体构件，其包括纵向延伸的中心区域，从中心区域的相对侧横向延伸的两个侧面区域，由中心区域和侧部区域限定的侧面一起形成凸的圆周表面，由凸面中心区域的表面和每个侧面区域的凹面，设置在中间表面的中心区域的凸面上或其中的多个纵向间隔开的电极，以及支撑结构，其包括多个纵向延伸的线每个连接到一个或多个电极，其中多个电线的子集设置在中心区域中，并且多个电线中的至少一个布置在一个侧部区域中。

6. 发明申请

US20090043370A1 PRE-CURVED COCHLEAR IMPLANT ELECTRODE ARRAY 有权
标题翻译：预弯曲COCHLEAR植入电极阵列
公开(公告)号：US20090043370A1
公开(公告)日：2009-02-12
申请号：US12250413
申请日：2008-10-13
申请人： Peter Gibson , Fysh Dadd , Claudiu Treaba , John Parker
发明人： Peter Gibson , Fysh Dadd , Claudiu Treaba , John Parker
IPC分类号： A61N1/00
CPC分类号： A61N1/0541 , A61F11/004 , B28B5/00
摘要： An implantable electrode array (30) that can adopt a first configuration selected to allow the array (30) to be inserted into a cochlea (12) of an implantee and at least a second configuration in which the array can apply tissue stimulation. The array (30) comprises an elongate carrier (31) having a proximal end (37), a distal end (34), and an inner surface (35) conformable with the inner wall of the implantee's cochlea (12). A plurality of electrodes (36) are supported within the carrier (31) at respective spaced locations thereon in a region between the proximal end (37) and the distal end (34) with at least one of the electrodes having a surface that is at least adjacent the inner surface (35) of the carrier (31). The carrier (31) is formed in the second configuration from a first layer (32) and at least a second layer (32) of resiliently flexible material. A method of forming an array (30) is also described.
摘要翻译：可植入电极阵列（30），其可以采用被选择以允许阵列（30）插入到植入物的耳蜗（12）中的第一配置和至少第二配置，其中阵列可以应用组织刺激。阵列（30）包括具有近端（37），远端（34）和与被植入物的耳蜗（12）的内壁相适合的内表面（35）的细长载体（31）。在近端（37）和远端（34）之间的区域中，多个电极（36）被支撑在载体（31）内的相应间隔位置处，其中至少一个电极具有处于最不邻近载体（31）的内表面（35）。载体（31）由第一层（32）和至少第二层（32）形成为弹性柔性材料。还描述了形成阵列（30）的方法。

7. 发明申请

US20070282416A1 Endosteal electrode 失效
标题翻译：内皮电极
公开(公告)号：US20070282416A1
公开(公告)日：2007-12-06
申请号：US11802400
申请日：2007-05-22
申请人： Peter Gibson , Ernst Lehnhardt , John Parker
发明人： Peter Gibson , Ernst Lehnhardt , John Parker
IPC分类号： A61N1/05
CPC分类号： A61N1/0541 , A61N1/36036
摘要： An implantable tissue-stimulating device comprising an elongate electrode carrier member (11) having a plurality of electrodes thereon. The electrodes are preferably disposed in a linear array on the carrier member (11) and are adapted to apply a preselected tissue stimulation to the cochlea. The carrier member (11) is preformed from a resiliently flexible biocompatible silicone and extends from a distal end (12) to a stop member (13). The carrier member (11) is adapted for intracochlear but extraluminar insertion within the cochlea of an implantee. In particular, the carrier member (11) is adapted to be implanted in the crevice (21) between the spiral ligament (22) and the endosteum (23) of the lateral wall of the cochlea (20). This is a quite different location to the normal placement of the cochlear implant electrode array in the scala tympani (24) of the cochlea (20). The placement of the carrier member (11) is designed to avoid any breach of the internal ducts of the cochlea (20), such as the scala tympani (24) and scala vestibuli (25) so that the normal hydrodynamic behaviour of the cochlea (20) is not affected by any intrusive device. By preservng the normal hydrodynamic behaviour of the cochlea (20), use of the carrier member (11) maximises the possibility of also preserving any hearing of the implantee that is offered by the cochlea (20). Use of the device in a system for masking or treating the symptoms of tinnitus is also described.
摘要翻译：一种可植入组织刺激装置，包括在其上具有多个电极的细长电极载体构件（11）。电极优选以线性阵列布置在载体构件（11）上，并且适于对耳蜗施加预选的组织刺激。载体构件（11）由弹性柔性的生物相容性硅树脂预成型，并从远端（12）延伸到止动构件（13）。载体构件（11）适于在植入物的耳蜗内进行耳内但外源性插入。特别地，载体构件（11）适于植入在螺旋韧带（22）和耳蜗（20）的侧壁的内壁（23）之间的缝隙（21）中。这是与耳蜗（20）的鼓膜鼓（24）中的人工植入电极阵列的正常放置相当不同的位置。载体构件（11）的放置被设计成避免耳蜗（20）的内部管道的任何破坏，例如鼓膜鼓膜（24）和裙带前庭（25），使得耳蜗的正常流体动力学行为 20）不受任何侵入设备的影响。通过保护耳蜗（20）的正常流体动力学行为，使用载体构件（11）最大限度地延长了保留由耳蜗（20）提供的植入物的任何听力的可能性。还描述了在用于掩蔽或治疗耳鸣症状的系统中使用该装置。

8. 发明申请

US20050080473A1 Endosteal electrode 审中-公开
标题翻译：内皮电极
公开(公告)号：US20050080473A1
公开(公告)日：2005-04-14
申请号：US10473925
申请日：2002-04-05
申请人： Peter Gibson , Ernst Lehnhardt , John Parker
发明人： Peter Gibson , Ernst Lehnhardt , John Parker
IPC分类号： A61N1/36 , A61F2/18 , A61F11/00 , A61N1/05
CPC分类号： A61N1/0541 , A61N1/36036
摘要： An implantable tissue-stimulating device comprising an elongate electrode carrier member (11) having a plurality of electrodes thereon. The electrodes are preferably disposed in a linear array on the carrier member (11) and are adapted to apply a preselected tissue stimulation to the cochlea. The carrier member (11) is preformed from a resiliently flexible biocompatible silicone and extends from a distal end (12) to a stop member (13). The carrier member (11) is adapted for intracochlear but extraluminar insertion within the cochlea of an implantee. In particular, the carrier member (11) is adapted to be implanted in the crevice (21) between the spiral ligament (22) and the endosteum (23) of the lateral wall of the cochlea (20). This is a quite different location to the normal placement of the cochlear implant electrode array in the scala tympani (24) of the cochlea (20). The placement of the carrier member (11) is designed to avoid any breach of the internal ducts of the cochlea (20), such as the scala tympani (24) and scala vestibuli (25) so that the normal hydrodynamic behaviour of the cochlea (20) is not affected by any intrusive device. By preservng the normal hydrodynamic behaviour of the cochlea (20), use of the carrier member (11) maximises the possibility of also preserving any hearing of the implantee that is offered by the cochlea (20). Use of the device in a system for masking or treating the symptoms of tinnitus is also described.
摘要翻译：一种可植入组织刺激装置，包括在其上具有多个电极的细长电极载体构件（11）。电极优选以线性阵列布置在载体构件（11）上，并且适于对耳蜗施加预选的组织刺激。载体构件（11）由弹性柔性的生物相容性硅树脂预成型，并从远端（12）延伸到止动构件（13）。载体构件（11）适于在植入物的耳蜗内进行耳内但外源性插入。特别地，载体构件（11）适于植入在螺旋韧带（22）和耳蜗（20）的侧壁的内壁（23）之间的缝隙（21）中。这是与耳蜗（20）的鼓膜鼓（24）中的人工植入电极阵列的正常放置相当不同的位置。载体构件（11）的放置被设计成避免耳蜗（20）的内部管道的任何破坏，例如鼓膜鼓膜（24）和裙带前庭（25），使得耳蜗的正常流体动力学行为 20）不受任何侵入设备的影响。通过保护耳蜗（20）的正常流体动力学行为，使用载体构件（11）最大限度地延长了保留由耳蜗（20）提供的植入物的任何听力的可能性。还描述了在用于掩蔽或治疗耳鸣症状的系统中使用该装置。

9. 发明授权

US08620459B2 Pre-curved cochlear implant electrode array 有权
标题翻译：预弯曲耳蜗植入电极阵列
公开(公告)号：US08620459B2
公开(公告)日：2013-12-31
申请号：US13175853
申请日：2011-07-03
申请人： Peter Gibson , Fysh Dadd , Claudiu Treaba , John Parker
发明人： Peter Gibson , Fysh Dadd , Claudiu Treaba , John Parker
IPC分类号： A61N1/05 , B28B5/00
CPC分类号： A61N1/0541 , A61F11/004 , B28B5/00
摘要： An implantable electrode array (30) that can adopt a first configuration selected to allow the array (30) to be inserted into a cochlea (12) of an implantee and at least a second configuration in which the array can apply tissue stimulation. The array (30) comprises an elongate carrier (31) having a proximal end (37), a distal end (34), and an inner surface (35) conformable with the inner wall of the implantee's cochlea (12). A plurality of electrodes (36) are supported within the carrier (31) at respective spaced locations thereon in a region between the proximal end (37) and the distal end (34) with at least one of the electrodes having a surface that is at least adjacent the inner surface (35) of the carrier (31). The carrier (31) is formed in the second configuration from a first layer (32) and at least a second layer (32) of resiliently flexible material. Manufacturing methods include molding the first and second layers into an array such as that described above.
摘要翻译：可植入电极阵列（30），其可以采用被选择以允许阵列（30）插入到植入物的耳蜗（12）中的第一配置和至少第二配置，其中阵列可以应用组织刺激。阵列（30）包括具有近端（37），远端（34）和与被植入物的耳蜗（12）的内壁相适合的内表面（35）的细长载体（31）。在近端（37）和远端（34）之间的区域中，多个电极（36）被支撑在载体（31）内的相应间隔位置处，其中至少一个电极具有处于最不邻近载体（31）的内表面（35）。载体（31）由第一层（32）和至少第二层（32）形成为弹性柔性材料。制造方法包括将第一层和第二层模制成如上所述的阵列。

10. 发明授权

US08460315B2 Insertion tool system for an electrode array 有权
标题翻译：电极阵列插入工具系统
公开(公告)号：US08460315B2
公开(公告)日：2013-06-11
申请号：US11261763
申请日：2005-10-31
申请人： Peter Gibson , John Parker , Claudiu Treaba
发明人： Peter Gibson , John Parker , Claudiu Treaba
IPC分类号： A61B19/00 , A61N1/00
CPC分类号： A61N1/0541 , A61B17/3468 , A61B2017/00787
摘要： A device used for inserting an electrode array into a cochlea of a subject. Particularly, the device is adapted for the insertion of electrode arrays having an elongate carrier member and a removable means extending through the carrier member. The device includes a handle, an elongate positioning member mounted to the handle, an actuator member movable relative to the elongate positioning member, and at least one anchor member connected to the actuator member and engageable with the removable means. On insertion of the electrode array into a subject's cochlea, the actuator member can be moved relative to the elongate positioning member to withdraw the removable means from the carrier member.
摘要翻译：用于将电极阵列插入到受试者的耳蜗中的装置。特别地，该装置适于插入具有细长承载构件的电极阵列和延伸穿过载体构件的可移除装置。该装置包括手柄，安装到手柄的细长定位构件，可相对于细长定位构件移动的致动器构件，以及连接到致动器构件并与可移除装置接合的至少一个锚定构件。在将电极阵列插入被检体的耳蜗中时，致动器构件可以相对于细长定位构件移动，以从载体构件中抽出可移除装置。

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